Myotis daubentonii (Daubenton's bat): 132234815
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Entry
132234815 CDS
T10294
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mdt Myotis daubentonii (Daubenton's bat)
Pathway
mdt01521
EGFR tyrosine kinase inhibitor resistance
mdt01522
Endocrine resistance
mdt01524
Platinum drug resistance
mdt04012
ErbB signaling pathway
mdt04014
Ras signaling pathway
mdt04015
Rap1 signaling pathway
mdt04024
cAMP signaling pathway
mdt04062
Chemokine signaling pathway
mdt04066
HIF-1 signaling pathway
mdt04068
FoxO signaling pathway
mdt04070
Phosphatidylinositol signaling system
mdt04071
Sphingolipid signaling pathway
mdt04072
Phospholipase D signaling pathway
mdt04081
Hormone signaling
mdt04140
Autophagy - animal
mdt04150
mTOR signaling pathway
mdt04151
PI3K-Akt signaling pathway
mdt04152
AMPK signaling pathway
mdt04210
Apoptosis
mdt04211
Longevity regulating pathway
mdt04213
Longevity regulating pathway - multiple species
mdt04218
Cellular senescence
mdt04360
Axon guidance
mdt04370
VEGF signaling pathway
mdt04380
Osteoclast differentiation
mdt04510
Focal adhesion
mdt04550
Signaling pathways regulating pluripotency of stem cells
mdt04611
Platelet activation
mdt04613
Neutrophil extracellular trap formation
mdt04620
Toll-like receptor signaling pathway
mdt04625
C-type lectin receptor signaling pathway
mdt04630
JAK-STAT signaling pathway
mdt04650
Natural killer cell mediated cytotoxicity
mdt04660
T cell receptor signaling pathway
mdt04662
B cell receptor signaling pathway
mdt04664
Fc epsilon RI signaling pathway
mdt04666
Fc gamma R-mediated phagocytosis
mdt04668
TNF signaling pathway
mdt04670
Leukocyte transendothelial migration
mdt04722
Neurotrophin signaling pathway
mdt04725
Cholinergic synapse
mdt04750
Inflammatory mediator regulation of TRP channels
mdt04810
Regulation of actin cytoskeleton
mdt04910
Insulin signaling pathway
mdt04914
Progesterone-mediated oocyte maturation
mdt04915
Estrogen signaling pathway
mdt04917
Prolactin signaling pathway
mdt04919
Thyroid hormone signaling pathway
mdt04923
Regulation of lipolysis in adipocytes
mdt04926
Relaxin signaling pathway
mdt04929
GnRH secretion
mdt04930
Type II diabetes mellitus
mdt04931
Insulin resistance
mdt04932
Non-alcoholic fatty liver disease
mdt04933
AGE-RAGE signaling pathway in diabetic complications
mdt04935
Growth hormone synthesis, secretion and action
mdt04960
Aldosterone-regulated sodium reabsorption
mdt04973
Carbohydrate digestion and absorption
mdt05010
Alzheimer disease
mdt05017
Spinocerebellar ataxia
mdt05020
Prion disease
mdt05100
Bacterial invasion of epithelial cells
mdt05135
Yersinia infection
mdt05142
Chagas disease
mdt05146
Amoebiasis
mdt05160
Hepatitis C
mdt05161
Hepatitis B
mdt05162
Measles
mdt05163
Human cytomegalovirus infection
mdt05164
Influenza A
mdt05165
Human papillomavirus infection
mdt05166
Human T-cell leukemia virus 1 infection
mdt05167
Kaposi sarcoma-associated herpesvirus infection
mdt05168
Herpes simplex virus 1 infection
mdt05169
Epstein-Barr virus infection
mdt05170
Human immunodeficiency virus 1 infection
mdt05171
Coronavirus disease - COVID-19
mdt05200
Pathways in cancer
mdt05203
Viral carcinogenesis
mdt05205
Proteoglycans in cancer
mdt05206
MicroRNAs in cancer
mdt05207
Chemical carcinogenesis - receptor activation
mdt05208
Chemical carcinogenesis - reactive oxygen species
mdt05210
Colorectal cancer
mdt05211
Renal cell carcinoma
mdt05212
Pancreatic cancer
mdt05213
Endometrial cancer
mdt05214
Glioma
mdt05215
Prostate cancer
mdt05218
Melanoma
mdt05220
Chronic myeloid leukemia
mdt05221
Acute myeloid leukemia
mdt05222
Small cell lung cancer
mdt05223
Non-small cell lung cancer
mdt05224
Breast cancer
mdt05225
Hepatocellular carcinoma
mdt05226
Gastric cancer
mdt05230
Central carbon metabolism in cancer
mdt05231
Choline metabolism in cancer
mdt05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mdt05415
Diabetic cardiomyopathy
mdt05417
Lipid and atherosclerosis
mdt05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mdt00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
132234815 (PIK3R2)
04014 Ras signaling pathway
132234815 (PIK3R2)
04015 Rap1 signaling pathway
132234815 (PIK3R2)
04370 VEGF signaling pathway
132234815 (PIK3R2)
04630 JAK-STAT signaling pathway
132234815 (PIK3R2)
04668 TNF signaling pathway
132234815 (PIK3R2)
04066 HIF-1 signaling pathway
132234815 (PIK3R2)
04068 FoxO signaling pathway
132234815 (PIK3R2)
04070 Phosphatidylinositol signaling system
132234815 (PIK3R2)
04072 Phospholipase D signaling pathway
132234815 (PIK3R2)
04071 Sphingolipid signaling pathway
132234815 (PIK3R2)
04024 cAMP signaling pathway
132234815 (PIK3R2)
04151 PI3K-Akt signaling pathway
132234815 (PIK3R2)
04152 AMPK signaling pathway
132234815 (PIK3R2)
04150 mTOR signaling pathway
132234815 (PIK3R2)
09133 Signaling molecules and interaction
04081 Hormone signaling
132234815 (PIK3R2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
132234815 (PIK3R2)
09143 Cell growth and death
04210 Apoptosis
132234815 (PIK3R2)
04218 Cellular senescence
132234815 (PIK3R2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
132234815 (PIK3R2)
04550 Signaling pathways regulating pluripotency of stem cells
132234815 (PIK3R2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132234815 (PIK3R2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132234815 (PIK3R2)
04613 Neutrophil extracellular trap formation
132234815 (PIK3R2)
04620 Toll-like receptor signaling pathway
132234815 (PIK3R2)
04625 C-type lectin receptor signaling pathway
132234815 (PIK3R2)
04650 Natural killer cell mediated cytotoxicity
132234815 (PIK3R2)
04660 T cell receptor signaling pathway
132234815 (PIK3R2)
04662 B cell receptor signaling pathway
132234815 (PIK3R2)
04664 Fc epsilon RI signaling pathway
132234815 (PIK3R2)
04666 Fc gamma R-mediated phagocytosis
132234815 (PIK3R2)
04670 Leukocyte transendothelial migration
132234815 (PIK3R2)
04062 Chemokine signaling pathway
132234815 (PIK3R2)
09152 Endocrine system
04910 Insulin signaling pathway
132234815 (PIK3R2)
04923 Regulation of lipolysis in adipocytes
132234815 (PIK3R2)
04929 GnRH secretion
132234815 (PIK3R2)
04915 Estrogen signaling pathway
132234815 (PIK3R2)
04914 Progesterone-mediated oocyte maturation
132234815 (PIK3R2)
04917 Prolactin signaling pathway
132234815 (PIK3R2)
04926 Relaxin signaling pathway
132234815 (PIK3R2)
04935 Growth hormone synthesis, secretion and action
132234815 (PIK3R2)
04919 Thyroid hormone signaling pathway
132234815 (PIK3R2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
132234815 (PIK3R2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
132234815 (PIK3R2)
09156 Nervous system
04725 Cholinergic synapse
132234815 (PIK3R2)
04722 Neurotrophin signaling pathway
132234815 (PIK3R2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
132234815 (PIK3R2)
09158 Development and regeneration
04360 Axon guidance
132234815 (PIK3R2)
04380 Osteoclast differentiation
132234815 (PIK3R2)
09149 Aging
04211 Longevity regulating pathway
132234815 (PIK3R2)
04213 Longevity regulating pathway - multiple species
132234815 (PIK3R2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132234815 (PIK3R2)
05206 MicroRNAs in cancer
132234815 (PIK3R2)
05205 Proteoglycans in cancer
132234815 (PIK3R2)
05207 Chemical carcinogenesis - receptor activation
132234815 (PIK3R2)
05208 Chemical carcinogenesis - reactive oxygen species
132234815 (PIK3R2)
05203 Viral carcinogenesis
132234815 (PIK3R2)
05230 Central carbon metabolism in cancer
132234815 (PIK3R2)
05231 Choline metabolism in cancer
132234815 (PIK3R2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
132234815 (PIK3R2)
09162 Cancer: specific types
05210 Colorectal cancer
132234815 (PIK3R2)
05212 Pancreatic cancer
132234815 (PIK3R2)
05225 Hepatocellular carcinoma
132234815 (PIK3R2)
05226 Gastric cancer
132234815 (PIK3R2)
05214 Glioma
132234815 (PIK3R2)
05221 Acute myeloid leukemia
132234815 (PIK3R2)
05220 Chronic myeloid leukemia
132234815 (PIK3R2)
05218 Melanoma
132234815 (PIK3R2)
05211 Renal cell carcinoma
132234815 (PIK3R2)
05215 Prostate cancer
132234815 (PIK3R2)
05213 Endometrial cancer
132234815 (PIK3R2)
05224 Breast cancer
132234815 (PIK3R2)
05222 Small cell lung cancer
132234815 (PIK3R2)
05223 Non-small cell lung cancer
132234815 (PIK3R2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
132234815 (PIK3R2)
05170 Human immunodeficiency virus 1 infection
132234815 (PIK3R2)
05161 Hepatitis B
132234815 (PIK3R2)
05160 Hepatitis C
132234815 (PIK3R2)
05171 Coronavirus disease - COVID-19
132234815 (PIK3R2)
05164 Influenza A
132234815 (PIK3R2)
05162 Measles
132234815 (PIK3R2)
05168 Herpes simplex virus 1 infection
132234815 (PIK3R2)
05163 Human cytomegalovirus infection
132234815 (PIK3R2)
05167 Kaposi sarcoma-associated herpesvirus infection
132234815 (PIK3R2)
05169 Epstein-Barr virus infection
132234815 (PIK3R2)
05165 Human papillomavirus infection
132234815 (PIK3R2)
09171 Infectious disease: bacterial
05135 Yersinia infection
132234815 (PIK3R2)
05100 Bacterial invasion of epithelial cells
132234815 (PIK3R2)
09174 Infectious disease: parasitic
05146 Amoebiasis
132234815 (PIK3R2)
05142 Chagas disease
132234815 (PIK3R2)
09164 Neurodegenerative disease
05010 Alzheimer disease
132234815 (PIK3R2)
05017 Spinocerebellar ataxia
132234815 (PIK3R2)
05020 Prion disease
132234815 (PIK3R2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132234815 (PIK3R2)
05418 Fluid shear stress and atherosclerosis
132234815 (PIK3R2)
05415 Diabetic cardiomyopathy
132234815 (PIK3R2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
132234815 (PIK3R2)
04932 Non-alcoholic fatty liver disease
132234815 (PIK3R2)
04931 Insulin resistance
132234815 (PIK3R2)
04933 AGE-RAGE signaling pathway in diabetic complications
132234815 (PIK3R2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132234815 (PIK3R2)
01524 Platinum drug resistance
132234815 (PIK3R2)
01522 Endocrine resistance
132234815 (PIK3R2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mdt04131
]
132234815 (PIK3R2)
Membrane trafficking [BR:
mdt04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
132234815 (PIK3R2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH3_1
SH3_9
Ribosomal_L22e
Motif
Other DBs
NCBI-GeneID:
132234815
NCBI-ProteinID:
XP_059552222
LinkDB
All DBs
Position
5:complement(19470970..19483339)
Genome browser
AA seq
727 aa
AA seq
DB search
MAGAEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQGLGVAEGSERCPQNVGWIPGL
NERTRQRGDFPGTYVEFLGPVTLARPGPRPRGPRPLPARPQEGPPEPGLTLPDLSEQFSP
PDVAPPLLVKLVEAIERTGLDSESLYRPELPPPCTDWSLSDLEQWDSAALADGIKGFLLA
LPAPVVTLEAAAEACRALREAAGPVGPTLEPPTLPLHHALTLRFLLQHLSRAARRAPAPG
PAVRALGVAFGPLLLRAPPPSPPPPGVPPVGTEPNPDFPALLVEKLLQEHLAEQEVAPPA
LPPKPPKVKPAPAGLANGGSPPSLQDAEWYWGDISREEVNDKLRDTPDGTFLVRDASSKI
QGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLITHYRHESLAQYNAKLDTRL
LYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAI
EAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTK
LEQELRTQALDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNET
EDQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLNGKRDGTFLIRESSQRGCYACSVVV
DGDTKHCVIYRTATGLGFAEPYNLYGSLKELVLHYQHTSLVQHNDALTVTLAHPVRAPGP
GPPPAAR
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atggctggcgccgaaggcttccagtaccgtgcactgtacccgttccgccgggagcggcca
gaagacctggagctgttgccgggtgacgtgctggtggtgagccgggccgccctgcagggg
ctgggtgtggccgagggcagcgagcgctgcccgcagaacgtgggctggatacctggcctc
aatgagcgaacccggcagcgcggtgacttccctggtacctacgtggagttcctggggcct
gtgaccctggcccggcctggccctcgcccccgcggcccccgcccactgcctgccaggccc
caagaggggccccctgagccaggcctcacactccctgacctatctgagcagttctcccca
cctgatgtggctcccccactgctggtaaagcttgtggaggccattgagcggacagggcta
gacagcgaatccctctacaggcccgagctgccgcccccgtgcacagactggtccctgagc
gacctagagcagtgggactcggcagccctggccgatggcatcaagggcttcctgctggca
ctgcctgcgcccgttgtgacgctggaagcggctgcagaggcctgccgtgccctgcgagag
gccgcggggcccgtggggccaactcttgagcccccgacgctgcccctgcaccacgcgctc
acgctgcgcttcctgctccagcacctgagccgggcggcccggcgcgcccctgccccaggt
cctgctgtgcgcgccctgggcgtcgccttcgggcctctgctgctgcgcgcgccgcctccc
tcgccgccaccgccaggggtcccaccggtcgggactgagcccaaccccgacttcccagct
ctgctggtggagaagttgcttcaggagcacctggcggagcaggaggtcgcacccccagct
ctgccacctaaaccacctaaagtcaagcccgccccagcagggctggccaatggggggagc
ccgccctctctgcaggatgctgagtggtactggggtgacatttccagggaggaggtgaac
gacaaactccgggacacacctgacggcaccttcctggtccgagatgcctccagcaagatt
cagggagagtataccctgacccttaggaaaggtggaaacaacaagctaattaaggtcttc
caccgtgatgggcattatggcttctcggagccgctcaccttctgctccgtcgtggacctc
atcacccactaccgccatgagtccctggcccagtacaatgccaaactagacacacggctc
ctgtaccccgtgtccaagtaccagcaggaccagattgtcaaggaagacagcgtggaggca
gtgggcgcccagctcaaagtctaccatcagcagtaccaggacaagagccgcgagtacgac
cagctctacgaggagtacacacgcacctcccaggaactgcagatgaagcgcaccgcaatc
gaggccttcaatgaaaccatcaagatcttcgaagagcagggccagactcaagagaagtgc
agcaaggagtatctggaacgcttccggcgtgagggcaatgagaaggagatgcagaggatc
ctgctgaactcagaacggctcaagtctcgcatcgccgagatccacgagagccgcacaaag
ctggaacaggagctgcggacacaggccttggacaaccgggagatcgataagcgcatgaac
agcctgaagccagacctcatgcagctgcgcaagatccgagaccagtacttggtatggctc
acccagaaaggcgcccggcagaagaaaatcaacgagtggttgggaatcaaaaatgagact
gaagaccagtacgcactgatggaggatgaggatgacctcccccaccatgaggaacgaacc
tggtatgtgggcaagatcaaccgcacgcaggctgaggaaatgctgaacggcaagcgggat
gggaccttcctcatccgtgagagcagccagcggggctgctacgcctgctctgtggtggtg
gacggcgataccaagcactgtgtcatctaccgcacggccactggcttgggttttgccgag
ccctacaacctgtacgggtctctgaaggagctggtgctgcattaccagcacacctccctc
gtgcaacacaacgacgcacttaccgtcacactggcacatcccgtgcgcgccccgggcccc
ggtccacccccggccgcccgctga
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