Methylorubrum extorquens AM1: Mex_1p1494
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Entry
Mex_1p1494 CDS
T00921
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mea
Methylorubrum extorquens AM1
Pathway
mea00270
Cysteine and methionine metabolism
mea00450
Selenocompound metabolism
mea00670
One carbon pool by folate
mea01100
Metabolic pathways
mea01110
Biosynthesis of secondary metabolites
mea01230
Biosynthesis of amino acids
mea04980
Cobalamin transport and metabolism
mea04981
Folate transport and metabolism
Module
mea_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mea00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Mex_1p1494 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
Mex_1p1494 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Mex_1p1494 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
Mex_1p1494 (metH)
04980 Cobalamin transport and metabolism
Mex_1p1494 (metH)
Enzymes [BR:
mea01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
Mex_1p1494 (metH)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Cas_Csm6_6H
Motif
Other DBs
NCBI-ProteinID:
ACS39356
UniProt:
C5AZM2
LinkDB
All DBs
Position
1559814..1563566
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AA seq
1250 aa
AA seq
DB search
MTAFPPVDGTEIERALRQRASEKILVLDGAMGTVIQRLKYTEEDFRGERFKDHSHDQKGN
NDLLILTQPNAIRQIHLDYFLAGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAR
EAAKLAEEQDGRRRFVAGAIGPTNRTLSISPDVNNPGYRAVTFDGVKQAYVEQVRGLIDG
GAELILIETIFDTLNAKAAIAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWN
SLRHSSPLTFGLNCALGAKEMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGK
LVGEFAASGLVNMVGGCCGTTPDHIRAIAEAVADKKPREIPEIPRLMRLSGLEPFVLTKE
IPFVNVGERTNVTGSAKFRKLITNNDYAAALDVARDQVAAGAQVIDVNMDEGLLDSEKAM
VEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEAKFIEAAKIC
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYKILTEQVGFPPEDIIFDPNIFAVATGIE
EHNPYGVAFIEATRTIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMD
MGIVNAGQLAVYDEIPAELRELCEDVVLNRREDSTERLLEAAERFKTGASAQAKTADLTW
REAPVAKRIEHALVNGITEYIVADTEEARKEAARPLHVIEGPLMAGMNVVGDLFGSGKMF
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGV
VLACNNYEIIDLGVMVPAAKILETAKRENVDIVGLSGLITPSLDEMVHVAAEMEREGMEM
PLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVSSLISKETRGATVEKVRAEY
AKVADAHRRSEADKQRLPLAKARANAFKVDWSAYKPAKPSFTGTRVYGSYEVADLVPYID
WTPFLQTYEFKGRYPAILDDPEQGPAARALFEDAQVMLKQIVEERWFNPKAVIGFWPANS
VGDDIRLFTGESRQETLATFHGLRQQLSKRDGRANTCISDFVAPAETGIADYVGAFVVTA
GLEEVRIAERFERANDDYRSILVKALADRIAEAFAERMHERVRKEFWGYAPDEAYAPEEL
VSEKYDGIRPAPGYPAQPDHTEKVQLFDLLKAESRIGVKLTESYAMWPGSSVSGLYLAHP
DAHYFGVAKVERDQVEDYALRKGMDVSEVERWLGPILNYDPVRYLKAAAE
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
atgaccgctttcccccccgtcgacggcaccgagatcgagcgcgccctgcgccagcgcgcg
tcggaaaagatcctcgtcctcgacggggcaatgggcacggtgatccagcggctcaaatac
acggaagaggatttccggggtgagcgcttcaaggatcacagccacgatcagaagggcaac
aacgacctcctgatcctgacgcagcccaacgcgatccggcagatccacctcgactacttc
ctcgccggcgccgacgtctgcgagacgaacacgttttccggcaccacgatcgcccaggcc
gattacggcatggaatcgatcatccacgagctgaacgccgaaggcgcccgcctcgcccgc
gaggccgccaagctggccgaagaacaggacggccgccgccgcttcgtcgccggcgccatc
ggcccgaccaaccgcacgctgtcgatctcgcccgacgtgaacaatcccggctaccgcgcc
gtgaccttcgatggggtgaagcaggcctatgtcgagcaggtgcgcggcctcatcgacggc
ggcgccgaactcatcctgatcgagacgatcttcgacacgctcaacgccaaggcggcgatc
gccgccgcgtggcaggtgttcgacgagaccggcatccgcctgccgatccagatctccggc
accatcaccgatctctccggccgcaccctgtcgggccagacgccggcggcgttctggaat
tcgctgcgccattcgagcccgctcaccttcggcctcaactgcgcgctcggcgccaaggag
atgcgcggccacatcgccgaactgtcgcgcatctgcgacacgctggtctgtgcctatccg
aatgccggcctgcccaacgagttcggtctctacgacgagagcccggaagccatgggcaag
ctcgtgggcgagttcgccgcctcgggcctcgtcaacatggtcggcggctgctgcggcacg
acaccggaccacatccgcgccatcgccgaggccgtggccgacaagaagccgcgcgagatc
cccgagatcccgcgcctgatgcgcctgtccggcctcgagcccttcgtgctgacgaaggag
attcccttcgtgaacgtgggcgagcgcaccaacgtcaccggctcggccaaattccgcaag
ctcatcaccaacaacgattacgccgccgcgctcgatgtcgctcgcgatcaggtcgcggcc
ggcgcccaggtcatcgacgtcaacatggatgagggcctgctcgacagcgagaaggcgatg
gtcgagttcctcaacctcgtcgccgccgagcccgacatcgcccgcgtgccggtgatggtc
gattcctcgaagttcgaggtgatcgaggccggcctgaaatgcatccagggcaagccgatc
gtgaactcgatctccatgaaggagggcgaggcgaagttcatcgaggccgccaagatctgc
cgctcctacggcgcggcggtggtcgtcatggccttcgacgagcagggccaggccgattcc
tacgagcgcaaggtcgagatctgcaccaaggcctacaagatcctcaccgagcaggtcggc
ttcccgcccgaggacatcatcttcgacccgaacatctttgctgtcgccacgggtatcgaa
gagcataacccctacggcgtcgccttcatcgaggcgacccgcacgatccgcgagaccctg
ccccacgcccacatctccggcggcgtctcgaacctgtccttcgccttccgcggcaacgag
ccggtgcgcgaggcgatgcacgcggtgttcctgttccactgcatcaaggccggcatggat
atgggcatcgtcaatgccggccagttggccgtctacgacgagatcccggccgaactgcgc
gaactgtgcgaggacgtggtcctcaaccgccgcgaggactcgaccgagcgcctgctggag
gccgccgagcgcttcaagaccggcgcctcggcccaggccaagaccgccgacctgacgtgg
cgcgaggcgcccgtcgccaagcgcatcgagcacgcgctggtcaacggcatcaccgagtac
atcgtcgccgacaccgaggaggcacgcaaagaggccgcgcgtccgctccacgtcatcgaa
ggcccgctgatggccggcatgaacgtggtcggcgacctgttcggctcgggcaagatgttc
ctgccgcaggtggtgaagtccgcccgcgtgatgaagcaggcggtggcctatctcgaaccc
ttcatggaggaggagaagcgggccaatggcggcgacggcaagcgccaggccgccggcaag
gtgctgatggccaccgtgaagggcgacgtccacgacatcggcaagaacatcgtcggcgtg
gttctggcctgcaacaattacgagatcatcgatctcggcgtgatggtgccggcggccaag
atcctcgagacggccaagcgcgagaacgtcgacatcgtcggcctgtcgggcctcatcacc
ccctcgctcgacgagatggtgcatgtcgccgccgagatggagcgcgagggcatggaaatg
ccgctgctgatcggcggcgccaccaccagccgcgtccacaccgcggtgaagatccacccg
gcctacgccaagggtcaggcggtctacgtcaccgatgcgagccgcgcggtcggcgtggtg
tcgagcctgatctcgaaggagacccgcggggccaccgtggagaaggtgcgcgccgaatac
gccaaggtcgccgacgcccatcgccgctccgaggccgacaaacagcgcctgccgctcgcc
aaggcgcgggcgaacgctttcaaagtggattggtcggcctacaagccggccaagcccagc
ttcaccggcacccgcgtctacggttcctacgaggtggcggacctcgtcccctacatcgac
tggacgccgttcctgcagacctacgagttcaagggccgctaccccgcgatcctcgacgat
cccgagcagggcccggcggcgcgtgcgctgttcgaggacgcgcaggtgatgctcaagcag
atcgtggaggagcgctggttcaacccgaaggcggtgatcggcttctggccggccaacagc
gtcggcgacgacatccggctcttcaccggcgagagccggcaggagacgctcgcgaccttc
cacggcctgcgccagcagctctcgaagcgcgacgggcgcgccaacacctgcatctccgac
ttcgtggcgccggccgagaccggcatcgcggactatgtcggcgccttcgtggtgacggcg
ggcctggaggaggtgcgcatcgccgagcgcttcgagcgggccaacgacgattaccgctcg
atcctcgtgaaggcgctcgccgaccgcatcgccgaggccttcgccgagcggatgcacgag
cgcgtccgcaaggagttctggggctatgcgccggacgaggcttacgcccccgaggagctg
gtctcggaaaagtacgacggcatccggcccgcgccgggctacccggcccagcccgaccat
acggaaaaggtgcagttgttcgatctgctcaaggcggagagccgcatcggcgtgaagctc
accgagtcctacgccatgtggccgggctcctcggtctcgggcctctacctcgcccatccc
gacgcccattacttcggcgtcgccaaggtggagcgggatcaggtcgaggactacgccctg
cgcaagggcatggatgtgagcgaggtcgagcgctggctcgggccgatcctcaactacgac
ccggtccgctacctcaaggccgcggccgagtag
DBGET
integrated database retrieval system
