KEGG   Melaminivora suipulveris: C6568_16825
Entry
C6568_16825       CDS       T05358                                 
Symbol
dfrA
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA6
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
mela  Melaminivora suipulveris
Pathway
mela00670  One carbon pool by folate
mela00790  Folate biosynthesis
mela01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mela00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    C6568_16825 (dfrA)
   00670 One carbon pool by folate
    C6568_16825 (dfrA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:mela01504]
    C6568_16825 (dfrA)
Enzymes [BR:mela01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     C6568_16825 (dfrA)
Antimicrobial resistance genes [BR:mela01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    C6568_16825 (dfrA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AVO50703
UniProt: A0A2R3QFZ4
LinkDB
Position
complement(3570618..3571091)
AA seq 157 aa
MKISLMAAVSENGVIGSGLDIPWHVQGEQLLFKAMTYNQWLLVGRKTFDSMGKLPNRKYA
VVTRSKIISNDPDVVYFASVESALAYLNNATAHIFVSGGGEIYKALIDQADVIHLSVIHK
HISGDVFFPPVPQGFKQTFEQSFSSNIDYTYQIWAKG
NT seq 474 nt   +upstreamnt  +downstreamnt
atgaaaatatctcttatggcagctgtttccgagaatggagtaattggctctggattggat
ataccttggcatgtacaaggcgagcagctcctattcaaagccatgacttacaatcaatgg
cttctagttggtcgtaaaaccttcgactcaatgggtaaacttccgaatagaaaatatgca
gtggttactcgttctaaaattatctcgaatgaccctgatgttgtgtatttcgcaagtgtt
gaatcggcattagcttacctaaacaatgcgacagcacatatctttgtttctggtggtggt
gaaatatataaagctttaatcgatcaagcagatgttatccatctttcagtgattcacaag
catatctctggcgatgtgttttttcctccagttccacagggcttcaagcaaacatttgag
caaagtttcagttcaaatattgattacacgtaccaaatttgggcaaagggctaa

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