Methylobacterium sp. 4-46: M446_6347
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Entry
M446_6347 CDS
T00679
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
met
Methylobacterium sp. 4-46
Pathway
met00909
Sesquiterpenoid and triterpenoid biosynthesis
met01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
met00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
M446_6347
Enzymes [BR:
met01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
M446_6347
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
M446_6347
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
TED_complement
Motif
Other DBs
NCBI-ProteinID:
ACA20611
LinkDB
All DBs
Position
complement(6973249..6975240)
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AA seq
663 aa
AA seq
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MGKVETLHRTSTQDITLDDVERRVTLASKALMRLANADGHWCFELEADATIPSEYILYHH
FRGSIPTAELEGKIAAYLRRTQSAQHDGWALIHDGPFDMSATVKAYFALKMVGDPIDAPH
MRRARDAILRRGGAAHANVFTRIMLALYGEVPWTAVPVMPVEVMLLPRWFPFHLDKVSYW
ARTVMVPLFVLQAKKPRARNPRGIGIRELFVEAPERVKRWPAGPQESSPWRPVFAAIDKV
LQKVEGFFPAGSRARAIDKAVAFVSERLNGEDGLGAIFPAMVNTVLMFEALGYPDDHPFA
VTARSSVEKLVTVKEHEAYVQPCLSPVWDTALAAHALMEAGGTEAERHAKRAMDWLKPLQ
VLDIKGDWAASKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRVQSRRSPGPDAADYGL
SIARAREWVEGLQSRDGGWAAFDADNTYHYLNYIPFSDHGALLDPPTADVTARCVSMLSQ
LGETRETCPPLDRGVAYLLADQEADGSWYGRWGMNYIYGTWSVLCALNAAGIDPACEPVR
RAVTWLTAIQNPDGGWGEDASSYKLEYRGYERAPSTASQTAWALLALMAAGEADNPAVAR
GINYLTRTQGADGLWAEDRYTATGFPRVFYLRYHGYAKFFPLWALARYRNLQRGNSLKVA
VGM
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
gtgggcaaggtcgagacgctccaccgcacgagcacgcaggacatcacgctcgacgacgtc
gagcggcgcgtcacgctcgcgtcgaaggctctcatgcggctcgcgaacgcggacgggcac
tggtgcttcgagctggaggccgacgccaccattccgtccgagtacatcctctaccatcat
ttccgcggctcgatcccgacggccgaattggaggggaagatcgccgcctacctgcgccgc
acccagagcgcgcagcacgacggctgggccctgatccatgacggccccttcgacatgagc
gcgaccgtcaaggcctacttcgccctcaagatggtcggcgacccgatcgacgcgccccac
atgcgccgggcccgcgacgcgatcctgcgccggggcggcgccgcccacgccaacgtcttc
acccggatcatgctcgccctctacggcgaggtgccgtggaccgccgtgccggtgatgccg
gtcgaggtgatgctgctgccgcggtggttccccttccacctcgacaaggtctcctactgg
gcccgcaccgtgatggtgccgctcttcgtcctgcaggccaagaagccgcgggcccgcaac
ccgcgcggcatcggcatccgcgaactcttcgtcgaggcgcccgagcgcgtgaagcgctgg
ccggccggcccgcaggaatcctcgccctggcgcccggtcttcgcggccatcgacaaggtg
ctgcagaaggtcgagggcttcttcccggccggctcgcgggcgcgggcgatcgacaaggcg
gtggccttcgtcagcgagcgcctgaacggcgaggacgggctcggcgcgatcttcccagcc
atggtcaacaccgtgctgatgttcgaggcgctcggctacccggacgaccaccccttcgcg
gtcacggcccgctcttcggtcgagaagctcgtcaccgtcaaggagcacgaggcctacgtc
cagccctgcctgtccccggtctgggacacggcgctcgccgcccacgccctgatggaagcc
ggcgggaccgaggcggagcgccacgccaagcgcgccatggactggctgaagcccctgcag
gtgctcgacatcaagggcgactgggcggcctccaagccggacgtgcggccgggcggctgg
gccttccagtacgccaacccgcactacccggacctcgacgacaccgcggtcgtggtgatg
gccatggaccgggtgcagagccgccgcagccccgggcccgacgcggccgattacgggctc
tcgatcgcccgcgcccgcgaatgggtcgagggcctgcagagccgcgacggcggctgggcg
gccttcgacgcggacaacacctaccactacctcaactacattccgttctcggatcacggg
gcgctgctcgacccgccgaccgccgacgtgacggcgcgctgcgtctcgatgctgtcccag
ctcggcgagacccgggagacctgcccgcccctcgaccgcggcgtcgcctacctgctcgcc
gatcaggaggcggatggcagctggtacggccgctggggcatgaactacatctacgggacg
tggtcggtgctctgcgccctcaacgcggccgggatcgaccccgcctgcgagccggtgcgg
cgggcggtgacctggctcaccgcgatccagaaccccgacggcggctggggcgaggacgcg
tcgagctacaagctcgaatatcgcggctacgagcgggcgccgagcacggcctcgcagacc
gcctgggcgctgctcgcgctgatggcggccggcgaggcggacaacccggccgtggcgcgc
ggcatcaactacctgacccgcacccagggggcggacgggctctgggccgaggaccgctac
acggcgaccgggttcccgcgcgtcttctacctgcgctaccacggctacgcgaagttcttc
cccctctgggcgctggcccgctaccgcaacctccagcggggcaacagcctcaaggtggcg
gtggggatgtga
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