KEGG   Methylobacterium radiodurans: DK427_23335
Entry
DK427_23335       CDS       T05919                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
meti  Methylobacterium radiodurans
Pathway
meti00270  Cysteine and methionine metabolism
meti00450  Selenocompound metabolism
meti00670  One carbon pool by folate
meti01100  Metabolic pathways
meti01110  Biosynthesis of secondary metabolites
meti01230  Biosynthesis of amino acids
meti04980  Cobalamin transport and metabolism
meti04981  Folate transport and metabolism
Module
meti_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:meti00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    DK427_23335
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    DK427_23335
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    DK427_23335
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    DK427_23335
   04980 Cobalamin transport and metabolism
    DK427_23335
Enzymes [BR:meti01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     DK427_23335
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AWN38313
UniProt: A0A2U8VWZ5
LinkDB
Position
4974656..4978408
AA seq 1250 aa
MTDFPPVDGTEIERALRQRASEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHAHDQKGN
NDLLILSQPDAIRQIHLDYFLAGADVCETNTFSGTTIAQADYGMESIIHELNAQGARLAR
EAAKLAQEKDGRRRFVAGAIGPTNRTLSISPDVNNPGYRAVTFDQVRQAYVEQVRGLIDG
GAELILIETIFDTLNAKAAVAAAWQVFEETGIRLPIQISGTITDLSGRTLSGQTPAAFWN
SLRHSSPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGK
LVGEFAESGLVNMVGGCCGTTPDHIRAIAEAVADKKPRAIPEIPRLMRLSGLEPFVLTKE
IPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSQKAM
VEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCLQGKPIVNSISMKEGEEKFIHDAKVC
RSYGAAVVVMAFDEQGQADTFERKVEICTRAYKVLTEQVGFPPEDIIFDPNIFAVATGIE
EHNPYGVAFIEATRKIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLYHCINAGMD
MGIVNAGQLAVYDEIPAELRELCEDVVLNRREDSTERLLEAAERFKTGASAQAKTADLSW
REGPVEKRIEHALVNGITEYIVADTEEARQAAERPLHVIEGPLMAGMNVVGDLFGSGKMF
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGTGQRQAAGKVLMATVKGDVHDIGKNIVGV
VLACNNYEIIDLGVMVPAAKILETAKREKVDIVGLSGLITPSLDEMVHVASEMEREGLEV
PLLIGGATTSRVHTAVKIHPAYERGQAVYVTDASRAVGVVSSLISKETRGATIDKVRAEY
AKVADAHRRSEADKQRLPLAKARANAFKIDWSGYKPTKPSFTGTRVYGSYEVADLVPYID
WTPFLQTYEFKGRFPAILDDPEQGPAARALFEDAQAMLKQIVEERWFNPKAVIGFWPANS
VGDDIALYTGESRQERLATFHGLRQQLSKRDGRPNTCLSDFVAPEGTGIADYVGGFVVTA
GLEEVRIAERFERANDDYRSILVKALADRIAEAFAERMHERVRKEFWGYAPDESFTADDL
VHEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAESRIGVKLTESYAMWPGSSVSGIYIGHP
EAHYFGVAKVERDQVEDYAARKGMDVAQVERWLGPILNYDPARYLAAAAE
NT seq 3753 nt   +upstreamnt  +downstreamnt
atgaccgacttcccccccgtcgacggcaccgagatcgagcgcgcgctgcgccagcgcgcc
tccgagaagatcctcgtcctcgacggggcgatgggcacggtgatccagcgcctgaagttc
tcggaagaggactttcgcggagatcgcttcaaggaccacgcgcacgaccagaagggcaat
aacgacctcctgatcctgtcgcagcccgacgcgatccggcagatccacctcgactacttt
ctggccggcgccgacgtctgcgagaccaatacgttctccggcaccacgatcgcccaggcc
gattacggcatggaatcgatcatccacgagctgaacgcgcaaggcgcccggctcgcccgc
gaggccgccaagctggcgcaggagaaggacggccgccgccggttcgtggccggcgccatc
ggcccgacgaaccgcacgctctcgatctcgccggacgtcaacaaccccggctaccgggcc
gtgaccttcgaccaggtccgccaagcctatgtcgagcaggtgcgcggcctgatcgacggc
ggcgccgagctgatcctgatcgagacgatcttcgacacgctgaacgccaaggccgcggtc
gccgccgcgtggcaggtcttcgaggagaccggcatccgattgccgatccagatctcgggc
acgatcacggacctgtccggccgcaccctgtcgggccagacgcccgccgccttctggaac
tcgctccgccattcgagcccgctcaccttcgggctgaactgcgcgctcggcgcgcgtgag
atgcgcggccacatcgccgagctgtcgcgcatctgcgacaccctggtctgcgcctacccg
aatgccggcctgcccaacgagttcggcctctacgacgagagcccggaggcgatgggcaag
ctcgtcggcgagttcgcggaatccggcctcgtcaacatggtcggcggctgctgcggcacc
acgccggaccacatccgggcgatcgcagaggccgtcgccgacaagaagccccgggcgatc
cccgagattccgcgcctgatgcggctgtcgggcctggagcccttcgtgctcacgaaggaa
atccccttcgtgaacgtgggcgagcgcacgaacgtcacggggtcggccaagttccgcaag
ctcatcaccaacggcgactacgcggccgcgctcgacgtcgcccgcgaccaggtcgcggcg
ggagcccaggtcatcgacgtcaacatggacgagggcctgctggattcccagaaggcgatg
gtcgagttcctcaacctcgtcgccgccgagcccgacatcgctcgcgtgccggtaatggtc
gattcctcgaagttcgaggtgattgaggccggcctgaagtgcctgcagggcaagccgatc
gtgaactcgatctccatgaaggagggcgaggagaagttcatccacgacgcgaaggtctgc
cgctcctacggcgccgcggtcgtcgtgatggccttcgacgagcagggccaggccgacacg
ttcgagcgcaaggtcgagatctgcacccgcgcctacaaggtgctgaccgagcaggtcggc
ttcccgcccgaggacatcatcttcgatccgaacatcttcgcggtcgcgaccggcatcgag
gagcacaacccctacggcgtcgccttcatcgaggccacgcgcaagatccgcgagaccctg
ccgcacgcccacatctcgggcggcgtctcgaacctgtccttcgccttccgcggcaacgag
ccggtgcgcgaggcgatgcacgcggtcttcctgtaccactgcatcaacgccggcatggac
atgggcatcgtgaatgccggccagctcgccgtgtacgacgagatcccggcggagctgcgc
gagctctgcgaggacgtcgtcctcaaccggcgcgaggactcgaccgagcgcctcttggag
gccgccgagcgcttcaagaccggcgcctccgcccaggccaagaccgccgacctctcctgg
cgcgagggaccggtcgagaagcgcatcgagcacgctctggtcaacggcatcaccgagtac
atcgtcgcggacacggaggaggcgcggcaagcggccgagcgcccgctccacgtcatcgag
ggtccgctgatggccggcatgaacgtggtcggcgacctgttcgggtcgggcaagatgttc
ctgccccaggtcgtgaagtcggcccgggtgatgaaacaggcggtggcctatctcgaaccc
ttcatggaggaggagaagcgggccaacggcggcaccggccagcgccaggccgccggcaag
gtgctgatggcgaccgtgaagggcgacgtccacgacatcggcaagaacatcgtcggcgtg
gttctggcctgcaacaactacgagatcatcgatctcggcgtgatggtgccggccgccaag
atcctggagacggccaagcgcgagaaggtcgacatcgtcggcctctcagggctgatcacg
ccctccctcgacgagatggttcacgtcgcctccgagatggagcgcgagggtctggaggtg
ccgctcctcatcggcggcgctacgacgagccgcgtccacaccgccgtgaagatccacccg
gcctacgagcgcggccaggcggtctacgtgacggatgcgagccgcgcggtcggcgtcgtc
tccagcctgatctcgaaggagacccgcggggcgacgatcgacaaggtgcgggccgagtac
gccaaggtggccgacgcccatcgccgctccgaggccgacaagcagcgcctgccgctggcc
aaggcgcgggccaacgccttcaagatcgactggtcgggctacaagccgacgaagccgagc
tttaccggaacgcgcgtctacgggtcgtacgaggtggcggacctcgtcccctacatcgac
tggacgcccttcctgcagacctacgagttcaagggccgctttcccgcgatcctcgacgat
cccgagcagggcccggccgcccgcgccctgttcgaggacgcgcaagccatgctcaagcag
atcgtggaggagcgctggttcaacccgaaggcggtgatcggcttctggccggccaacagc
gtcggcgacgatatcgcgctctataccggcgagagccggcaggagcggcttgcgaccttc
cacggcctgcgccagcagctctcgaagcgcgacgggcgcccgaatacctgcctgtcggac
ttcgtggcgccggaggggaccggcatcgccgattacgtgggcggcttcgtcgtgacggcg
ggcctggaggaggtgcgcatcgccgagcgcttcgagcgggcgaacgacgattaccgctcg
atcctcgtcaaggcgctcgccgaccgcatcgccgaggccttcgccgagcgcatgcacgag
cgggtgcgcaaggagttctggggctacgcgcccgacgagagcttcaccgccgacgatctc
gtgcacgagaagtacgatggcatccgcccggcacccggctacccggcccagcccgaccac
accgagaagacgactttgttcgacctcctcaaggctgagagccgcatcggcgtgaagctc
accgaatcctacgcgatgtggcccggttcctccgtgtcgggcatctatatcggccatccg
gaggcgcactatttcggcgtcgccaaggtcgagcgcgatcaggtcgaggactacgccgcc
cgcaagggcatggacgtggcgcaagtcgagcgctggctcgggccgatcctgaactacgac
ccggcccgctacctcgcggctgccgccgaatag

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