KEGG   Methylococcus geothermalis: GNH96_07615
Entry
GNH96_07615       CDS       T06585                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
metu  Methylococcus geothermalis
Pathway
metu00270  Cysteine and methionine metabolism
metu00450  Selenocompound metabolism
metu00670  One carbon pool by folate
metu01100  Metabolic pathways
metu01110  Biosynthesis of secondary metabolites
metu01230  Biosynthesis of amino acids
metu04980  Cobalamin transport and metabolism
metu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:metu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    GNH96_07615 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    GNH96_07615 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    GNH96_07615 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    GNH96_07615 (metH)
   04980 Cobalamin transport and metabolism
    GNH96_07615 (metH)
Enzymes [BR:metu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     GNH96_07615 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding MtrH
Other DBs
NCBI-ProteinID: QJD29852
UniProt: A0A858Q7H3
LinkDB
Position
1578926..1582639
AA seq 1237 aa
MTIAVTAAERSSLLRSLLKERILFLDGAMGTMIQRYKLEEADYRGERFADWPQDVKGNND
LLSLTRPDVIEAIHWAYLEAGADILETNTFNATRISMADYGMEELVYEINVTSARLARGA
ADRMSEQTPDRPRFVAGVLGPTSRTASISPSVNDPGFRNISFDELVASYTEAVRGLVDGG
ADIVLIETIFDTLNAKAAVFAVDQFFERQGFSLPVMISGTITDASGRTLSGQTVEAFWNS
LRHARPLSIGLNCALGAKQLRQHVEELSRIADTHVSAHPNAGLPNEFGEYDESPEAMARE
IADWAEQGFLNIIGGCCGTTPPHIKAIHDAVEHFPPRRIPAIPPACRLAGLEPCNITADS
LFVNVGERTNVTGSAAFRRLIRDEKYDEALDIARQQVESGAQIIDVNMDEGMLDSRAAMV
QFLNLIASEPDIARVPVMIDSSKWDILEAGLKCIQGKGIVNSISLKEGEAVFLHHARLVR
RYGAAVIVMAFDEQGQADTRERKIEICERAYKLLTEQVGFPAEDIIFDPNIFAVATGIDE
HNRYGLDFIEAVAEIKARLPHALISGGVSNVSFSFRGNNPVREAIHAVFLYHAIRAGMDM
GIVNAGQLAIYEEVPAELREAVEDVILARREDATERLLAIADRYRGEEGAVGERKADLAW
RALPVDKRLEHALVKGIDEFIEADTEEARQRFERPLHVIEGPLMAGMNVVGDLFGAGKMF
LPQVVKSARVMKKAVAYLMPYMDAERNGGVASSNGKILMATVKGDVHDIGKNIVGVVLQC
NGFEVVDLGVMVPCDRILQTAREENVDIIGLSGLITPSLDEMVHVAKEMERLGFEIPLMI
GGATTSRAHTAVKIEPNYRGPTVYVSDASRSVGVASSLLSGDLKDEFTATVRKEYEEVRR
HHAGRRAQGTLLSLEQARAKAFHTDWAHYAPPVPRLLGLEVFDAYPLEEIADYIDWSPFF
HTWELAGSYPKILDDEVVGDHARTLLQDARAMLALLIEQRWLTARGVIGFFPANSEGDDI
VLWTDENRREWLAVLHHLRQQQEKPGGQPDYCLADFIAPVGSGVADYLGGFAVTAGHGIE
GHLERFARAHDDYSGIMLKALADRLAEAFAELMHRRVRREFWGYAPDESLGNDALIAEEY
RGIRPAPGYPACPDHTEKATLFRLLDAEANTGIALTESFAMYPASSVSGWYFSHPTAKYF
NVGKLGRDQVEDYARRKGMAVREVERWLASSLGYDAD
NT seq 3714 nt   +upstreamnt  +downstreamnt
atgaccattgccgttaccgctgcggagcgctcctcgctcctaagaagcctgctcaaggag
cgcatcctgtttctcgatggcgccatgggcaccatgattcagcgctacaagctggaggag
gccgattaccggggcgagcgcttcgccgactggccgcaggatgtcaagggcaacaacgac
ctcttgtcgctgacccgtccggacgtgatcgaggccatccactgggcctatctcgaagcc
ggcgccgacatcctggaaaccaataccttcaacgccacccgcatcagcatggcggattat
ggcatggaagagctggtgtacgagatcaacgtgacttccgcccgcctggcccgcggagca
gcggaccgcatgagcgagcagaccccggatcggccgcgcttcgtcgccggcgtgctgggg
ccgaccagccgaaccgcgtcgatttcgccctcggtgaacgatcccggcttccgcaacatc
agcttcgacgagctggtggcgtcctataccgaggccgtgcgtggcctggtcgacggtggc
gccgacatcgtactgatcgagacgatcttcgacaccctcaacgccaaggcggcggttttc
gcggtggatcagttcttcgagcggcaaggcttcagcctgccggtgatgatttccggcacc
atcaccgacgcttcggggcgtacgctttcgggacagaccgtggaagccttctggaattcg
ctgcgccatgcccggccgctttcgatcggcctgaactgcgcactcggcgccaagcaactg
cggcagcacgtcgaggaactgtcgcgcatcgccgatacccatgtctcggcccatcccaac
gcgggcctgccgaacgaattcggcgagtacgacgaatcgcccgaggccatggcgcgcgag
atcgccgactgggccgagcagggcttcctcaacatcatcggcggctgctgcggcaccacg
ccgccacacatcaaggcgatccatgatgcggtcgaacatttcccgccgcggcggatcccc
gcgattcccccggcctgccggttggccggactggaaccctgcaacatcaccgcggactcg
ctgttcgtcaacgtcggcgagcgcaccaacgtcaccggttcggcggcgttccggcgcctg
atccgcgacgagaaatacgacgaggcgctggacatcgcccgccagcaggtcgagagcggc
gcccagatcatcgacgtcaacatggacgaaggcatgctggattcgcgtgccgcgatggtg
caattcctcaatctcatcgcctccgagcccgacatcgcgcgggtaccggtgatgatcgat
tcgtccaagtgggacatcctggaggccgggctcaagtgcatccagggcaagggcatcgtc
aactcgatctcgctcaaggagggggaggcggtctttctccaccatgcgcggctggtacgg
cgctacggcgcggcggtgatcgtcatggccttcgacgagcagggccaggccgatacccgt
gagcgcaagatcgagatttgcgagcgggcctacaaactgctgaccgaacaggtcggcttc
ccggccgaagacatcatcttcgatccgaatattttcgcggtggcgaccggcatcgatgag
cacaaccgttacggcctggatttcatcgaagccgtcgccgagatcaaggcccgcctgccg
catgcgctgatttccggcggcgtgtccaacgtgtcgttctcgttccgcggcaacaacccg
gtgcgcgaggcgatccatgcggtgttcctgtatcacgccatccgcgccgggatggacatg
ggcatcgtcaatgccggtcagctcgcgatctacgaagaggtgccggcggaattgcgggag
gcggtggaggacgtcatcctcgcccgccgcgaggatgccaccgaacgcctgctcgccatc
gccgaccgttaccggggcgaggagggcgccgtgggcgagcgcaaggccgacctggcctgg
cgtgccctgccggtggacaagcgcctggagcacgccctggtcaagggcatcgacgaattc
atcgaagccgataccgaagaggcccggcagcggttcgagcgaccgctgcacgtcatcgag
gggccgctgatggccgggatgaacgtggtcggcgacctgttcggcgccggcaagatgttc
ctgccccaggtggtcaaatcggcgcgggtgatgaagaaggccgtggcctacctgatgccg
tacatggacgcggagcggaacggtggcgttgcgagttccaacggcaagatcctgatggcg
acggtgaagggcgacgtccacgacatcggcaagaacatcgtcggcgtggtgctgcaatgc
aacggctttgaggtggtcgacctgggtgtgatggtgccatgcgacaggatattgcagacc
gcccgcgaggagaacgtcgacatcatcggcctgtccggcctgatcacgccttcgctggac
gagatggtgcacgtcgccaaggaaatggagcggctgggattcgagattccgctcatgatc
ggcggcgcgacgacttcgcgggcgcacacggcggtcaagatcgagcccaattaccggggg
ccgacggtctacgtctcagacgcctcgcgcagcgtcggtgtggcgagcagcctgctgagc
ggcgatctcaaggacgaattcaccgccacggtgcgcaaggaatacgaggaggtgcggcgt
catcacgccgggcgccgcgcccaagggaccctattgagcctggagcaggcgcgggccaag
gctttccataccgactgggcccattacgcgccgcccgtgccgcgcctgttggggctggag
gtgttcgatgcctatccgctggaagagatcgccgactacatcgactggtcgccgttcttc
catacctgggagctggccggcagttatccgaagatattggacgacgaagtggtgggcgat
catgcccgcacgctgctgcaggacgcccgcgccatgctggcgctcttgatcgaacagcgc
tggctcacggcccgcggcgtgatcggttttttcccggccaattcggaaggggacgacatc
gtgctgtggaccgacgaaaaccgcagggaatggctggcggtgttgcaccatctgcgccag
caacaggaaaagccgggcggccagccagactattgcctcgcggatttcatcgcgccggtc
ggcagcggggtggcggattatctgggcggcttcgccgtgaccgccggccatggcatcgag
gggcatcttgaacgcttcgcccgggcccacgacgactacagcggcatcatgttgaaggcc
cttgccgatcggctggccgaggctttcgcggagctgatgcaccggcgggtgcggcgggaa
ttctggggctatgcgccggacgaatctttgggcaacgatgcgctgattgccgaggaatat
cgcggcatccggccggcgccgggctatccggcctgccccgaccacaccgaaaaggccacg
ctgttccgcctgctggacgccgaagccaacaccggcatcgccttgaccgaaagcttcgcc
atgtatccggcatcgtccgtcagcggctggtatttctcgcatcctacggcgaaatatttc
aatgtcggcaagctcggccgcgaccaggtcgaggactacgcccggcgcaaggggatggcg
gtacgcgaggtcgagcgctggctggcgtccagtctcggctacgatgccgactga

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