KEGG   Methylobacterium sp. XJLW: A3862_20210
Entry
A3862_20210       CDS       T05508                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
metx  Methylobacterium sp. XJLW
Pathway
metx00270  Cysteine and methionine metabolism
metx00450  Selenocompound metabolism
metx00670  One carbon pool by folate
metx01100  Metabolic pathways
metx01110  Biosynthesis of secondary metabolites
metx01230  Biosynthesis of amino acids
metx04980  Cobalamin transport and metabolism
metx04981  Folate transport and metabolism
Module
metx_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:metx00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    A3862_20210
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    A3862_20210
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    A3862_20210
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    A3862_20210
   04980 Cobalamin transport and metabolism
    A3862_20210
Enzymes [BR:metx01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     A3862_20210
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AWV19620
LinkDB
Position
4418801..4422553
AA seq 1250 aa
MTDFAPVDGTAIAQALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGN
NDLLILTQPDAIRQIHLDYFLAGADVCETNTFSGTTIAQADYGMESIIHELNREGARLAR
EAARLAEETDGRRRFVAGAIGPTNRTLSISPDVNNPGFRAVTFDQVKQAYVEQVRGLIDG
GAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWH
ALRHSDPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGK
LVGEFAESGLVNMVGGCCGTTPDHIRAIAEAVAGKAPRPIPEIPRLMRLSGLEPFVLTPE
IPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSQKAM
VEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVC
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIE
EHNGYGVAFIEATRTIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIQAGMD
MGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLEAAERFKTGASAQAKTADLTW
REAPVGKRIEHALVNGITEYILADTEEARQGVERPLHVIEGPLMAGMNVVGDLFGAGKMF
LPQVVKSARVMKQAVAYLEPYMEAEKLANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGV
VLACNNYEIIDLGVMVPAAKILETAKREQVDIVGLSGLITPSLDEMVHVAGEMEREGMDV
PLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVSSLISKETRGPTIEKVRAEY
AKVADAHKRSEVDKQRLPLAKARANAFKVDWSGYKPAKPTFTGTRVYGSYEVADLVPYID
WTPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQAMLKQIVEERWFNPKAVIGFWPANS
VGDDIALYTGESRSERLATFHGLRQQLSKRDGRANTCLSDFVAPSETGIADYVGGFVVTA
GLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHERVRKEFWGYATEEAYAPEEL
VLEKYDGIRPAPGYPAQPDHTEKTTLFDLLRAESRIGVKLTESYAMWPGSSVSGIYIAHP
EAHYFGVAKVERDQVEDYAVRKGMDVREVERWLGPILNYDPARYLAQAAE
NT seq 3753 nt   +upstreamnt  +downstreamnt
atgaccgattttgcccccgtcgacggtaccgcgatcgcacaggcgctgcgccagcgcgcg
gcggagaagatcctcgtcctcgacggtgcgatgggcaccgtgatccagcggctgaagttc
tcggaagaggattttcgcggcgaccggttcaaggatcacggccacgatcagaagggcaac
aacgacctcctgatcctgacccagcccgacgcgatccggcagatccacctcgactacttc
ctggccggcgccgacgtctgcgagaccaacaccttctcgggcaccaccatcgcccaggcc
gattacggcatggagtcgatcatccacgagttgaaccgggagggcgcgcgtctcgcccgc
gaggccgccaggctcgccgaggagacggacggccgccgccgcttcgtggccggcgccatc
ggcccgacgaaccgcaccctgtcgatctcgccggacgtgaacaacccgggcttccgggcc
gtcaccttcgatcaggtcaagcaggcctacgtggagcaggtccgcggcctgatcgacggg
ggcgccgagctgatcctgatcgagaccatcttcgacacgctcaacgccaaggccgcggtg
gcggcggcgtggcaggtcttcgacgagaccggcatccggctgccgatccagatctccggc
acgatcacggatctctcgggccgcaccctgtcgggtcagaccccggcggccttctggcac
gccctgcgccattccgatccgctgaccttcggcctcaattgcgcgctgggcgcccgcgag
atgcgcggccacatcgccgagctgtcgcggatctgcgacacgctggtctgcgcctatccg
aatgccggcctgcccaacgagttcggcctctacgacgagagcccggaggccatgggcaag
ctcgtcggcgagttcgccgaatccggcctcgtcaacatggtcggcggctgctgcggcacc
accccggaccatatccgcgccatcgcggaggccgtcgccggcaaggcgccgcggccgatc
cccgagatcccccgcctgatgcggctgtcgggcctcgagcccttcgtgctcacgccggaa
atccccttcgtgaacgtcggcgagcgcacgaacgtcaccggctcggccaagttccgcaag
ctcatcaccaacggcgactacgcggcggcgctcgacgtcgcccgcgatcaggtggcggcc
ggcgcccaggtgatcgacgtcaacatggacgagggcctgctcgactcccagaaggcgatg
gtcgagttcctcaacctcgtcgccgccgagcccgacatcgcccgggtgcccgtgatggtc
gattcctcgaagttcgaggtgatcgaggcggggctcaagtgcatccagggcaagccgatc
gtgaactcgatctccatgaaggagggcgaggagaagttcatcgaggccgccaaggtctgc
cgctcctacggcgccgccgtggtggtgatggccttcgacgagcaggggcaggcggattcc
tacgagcgcaaggtcgagatctgcaccaaggcctaccggatcctgaccgagcaggtcggc
ttcccgcccgaagacatcatcttcgacccgaacatcttcgcggtcgccaccggcatcgag
gagcataacggctacggcgtcgccttcatcgaggcgacccgcacgatccgcgagaccctg
ccgcacgcccacatctcgggcggcgtctcgaacctgtccttcgcgttccgcggcaacgag
ccggtgcgcgaggcgatgcacgcggtgttcctgttccactgcatccaggcgggcatggac
atgggcatcgtcaatgccggccagctcgccgtctacgacgagatcccggcggagctccgc
gagctctgcgaggacgtggtcctcaaccggcgcgacgattccaccgagcgcctgctggag
gccgccgagcggttcaagaccggcgcctcggcccaggccaagaccgccgacctgacctgg
cgcgaggcgccggtcgggaagcgcatcgagcacgccctggtcaacggcatcaccgagtac
atcctggccgacaccgaggaggcccgccagggcgtggagcggccgctccacgtcatcgag
ggcccgctgatggccggcatgaacgtggtcggcgacctgttcggcgcgggcaagatgttc
ctgccgcaggtggtgaaatccgcccgggtgatgaagcaggcggtggcctatctcgagccc
tacatggaggccgagaagctcgccaatggcggcgacggcaagcgccaggccgccggcaag
gtgctgatggccaccgtgaagggcgacgtccacgacatcggcaagaacatcgtcggcgtc
gtgctggcctgcaacaactacgagatcatcgatctcggcgtgatggtgccggccgccaag
atcctggagaccgccaagcgcgagcaggtcgacatcgtcggcctgtccggcctgatcacc
ccgtcgctcgacgagatggtccacgtggcgggcgagatggagcgcgagggcatggacgtg
ccgctgctgatcggcggcgccaccacgagccgcgtccacacggcggtgaagatccacccg
gcctacgccaaggggcaggccgtctacgtcaccgacgcgagccgggcggtcggcgtggtg
tcgagcctgatctccaaggagacccgtgggcccacgatcgagaaggtccgggccgagtac
gccaaggtcgccgacgcccataagcgctcggaggtcgacaagcagcggctgccgctggcc
aaggcgcgggccaacgccttcaaggtcgactggtcgggctacaagccggccaagccgacc
ttcaccggcacccgggtctacggctcctacgaggtcgccgacctcgtgccctacatcgac
tggacgccgttcctgcagacctacgagttcaagggccgctttccggcgatcctggacgat
cccgagcagggaccggccgcccgcgccctctacgaggacgcgcaggcgatgctgaagcag
atcgttgaggagcgctggttcaacccgaaggcggtgatcggcttctggccggccaacagc
gtcggcgacgacatcgcgctctacaccggcgagagccggtcggagcggctcgccaccttc
cacggcctgcgccagcagctctcgaagcgcgacgggcgcgccaacacctgcctgtcggac
ttcgtggcgccttccgagaccggcatcgccgactatgtcggtggcttcgtggtgacggcc
ggcctggaggaagtgcggatcgccgagcgcttcgagcgggccaacgacgattaccgggcg
atcctggtcaaggcgctcgccgaccgcatcgccgaggccttcgccgagcggatgcacgag
cgggtgcgcaaggagttctggggctacgcgacggaggaggcctacgcccccgaggagctg
gtgctggagaaatacgacggcatccgcccggctcccggctacccggcccagcccgaccac
accgagaagacgaccctgttcgacctgctgcgggccgagagccggatcggcgtgaagctc
accgaatcctacgccatgtggccgggctcgtcggtgtcggggatctacatcgcccacccg
gaggcgcactatttcggcgtcgccaaggtggagcgggatcaggtcgaggattacgccgtc
cgcaagggcatggatgtccgcgaggtcgagcgctggctcgggccgatcctgaactacgat
ccggcgcggtacttggcgcaggcggcggagtag

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