KEGG   Candidatus Methylacidiphilum fumarolicum: MFUM_1676
Entry
MFUM_1676         CDS       T09357                                 
Symbol
acrB
Name
(GenBank) Cation/multidrug efflux pump
  KO
K18138  multidrug efflux pump
Organism
mfh  Candidatus Methylacidiphilum fumarolicum
Pathway
mfh01501  beta-Lactam resistance
mfh01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:mfh00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    MFUM_1676 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    MFUM_1676 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mfh02000]
    MFUM_1676 (acrB)
   01504 Antimicrobial resistance genes [BR:mfh01504]
    MFUM_1676 (acrB)
Transporters [BR:mfh02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   MFUM_1676 (acrB)
Antimicrobial resistance genes [BR:mfh01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    MFUM_1676 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL
Other DBs
NCBI-ProteinID: CAI9086007
LinkDB
Position
MFUM:complement(1614099..1617290)
AA seq 1063 aa
MTLSDLSIRRPVFAWMLMIGLIFFGIVALFRLGISQLPEIDFPIITINLQWNGASPEILE
TELVDPIEQAVISAQGLKGISSYIQLGQASIILEFELGRNIDSALTEVQSKISSVKLPMD
PTQQVGMQQVPTPVPQPILVKDNPEEQPILLVGVFGEHKTLHDLVTFVDLVLHDELQIVP
GVGQIVLAGYNVRNLRIWADSKKLAQYQLTVQDLQTAIMQEHVEVAAGDLENPHKQFNVR
AMGEGLSPEEVGNIQIKKRGSELIYRSNIRIKDVAKVEDGLDDIRRIAASNGQTIIGVGI
KKQPGANSVEVARLVKKKLSEIQPFLPKGIHLSVVYDRTKHIEDSIKETLFTLGLSAVIT
SLVCYLFLGSWTATLNVLLSIPTSVLGTFIVIYFLGFTLNFFTLLGLSLAIGIIVDDAIM
VLENIYRHRDMKKTRVMAARDGAREITFAAMAATVAIIAIFLPVAFMKGVIGKYFYQFGL
TISAAVALSLLEAITLTPMRCSQIMDDSYQRKGLAYIVDYSFKSLAKVYKYLLKFCIFYP
WLVILGALSVFLYSLKLFSFLPQELIPTQDESSFIIRIQTPVGSSIYYTEEKLKECEKLI
LSHQEVEKVFGEVGGMIQRTGATDGNLVDSEVNVGTIYVTLKDKKERVLSQRILMDTLRE
ELNKLKDLRATPQDLSIRGFTTGRGFPIELTIRGEDYKVLEKIVQEDIEEMKKSGYFVDL
DTDFRDGMPEVRVYPDRFAANACSIPIQNIANTVAIAIGGIAQGQFTNGERRYDIRIRLR
GDERVGPEDIARLGIRTNTNEFMPITSVAKLQTVQTYQTLTRKMRERAITIFANVASGKS
QAQALVVAKKICSKNLPKGYRLFLSGGAASFEETFQSLVFAIWVGVVIAYMVLASQFNSF
VHPFSVLLALPFSLSGALLALWFTHQSINLYSMIGLVLLMGIAKKNSILLVEFTNQLRYK
GLSIKEAILEAAPIRLRPILMTSMATIAAAIPPALALGPGAESRIPMAITLLGGIAVSTV
FTLFVVPAAYLLLSRFEKSRPFLIQPQTAPVGKEEESLVEKKD
NT seq 3192 nt   +upstreamnt  +downstreamnt
atgaccctttctgatctttccattcgcaggcctgtatttgcgtggatgttgatgattggg
ttaattttttttggtattgttgctctttttagattaggaattagtcagcttcctgagatc
gatttcccgattattactataaacctgcaatggaatggggcttctcccgaaattcttgaa
acagaacttgtcgatcccattgaacaagcagtgatttcggcacaagggcttaaagggata
agttcctatattcaattggggcaggcatccatcatcttagagtttgaacttggcaggaac
atcgattcagccttgaccgaagtacaatcgaagataagctcggtcaaattaccaatggat
ccaactcagcaggtgggcatgcaacaggtccctactcctgttccacaaccaattcttgtc
aaagataatcctgaagagcagcctattttattggttggagtctttggagagcacaagact
cttcatgatcttgtcacttttgtggatcttgtgctgcatgacgagttacaaattgttcca
ggtgttggtcagattgtcttagctgggtataatgtcagaaatttaagaatttgggcggat
agtaaaaagttggcgcagtaccaattgaccgttcaagatcttcaaacggcgatcatgcag
gaacacgtggaagtggctgcaggggatcttgaaaacccacataagcaattcaatgtgaga
gccatgggtgaaggactaagtcctgaagaagtaggcaatattcaaattaaaaaaaggggc
tcagaactcatttatagatcgaacatacggataaaggatgtagcaaaggtagaggacgga
ttggatgatattcgacgcattgcggctagcaatggacagactattattggtgtcggtata
aaaaagcaacccggagcaaattccgtggaagtggctcgattggtcaaaaaaaagttatcg
gaaattcaaccctttcttccaaaaggaatccatctcagcgtagtctatgatagaacaaaa
catatagaagattcgattaaggaaaccttatttacccttgggctttcagctgttatcacc
agcttggtctgttatctgttcctcggaagctggactgccacccttaatgtgttgctttct
atacccacttctgttcttggaacctttattgtcatttactttttaggttttactttgaat
ttctttactctccttggcctttccttggccattgggattattgtcgatgacgcgatcatg
gttcttgaaaatatctataggcatcgggatatgaaaaagacaagggtgatggcagccaga
gatggggctagagaaatcacctttgctgctatggctgctactgtggctattatcgccatt
tttcttcctgttgcttttatgaagggggtcataggcaagtatttttatcaatttggtctt
acgatttcggctgcagtagccctctcgctgttggaagccatcaccctaacacctatgcgc
tgttcccaaattatggatgactcttaccaaagaaaaggcttagcctatatcgtcgattac
tccttcaaaagtcttgccaaagtgtataagtatcttttgaagttttgtatcttttatccc
tggcttgtgatcctgggagctttaagtgtttttctttattcgttgaagcttttcagtttt
ctacctcaggaactgattcccactcaagacgaatcttctttcattattcggattcaaacc
ccggtaggctcgtcgatttactataccgaagaaaagctcaaagaatgtgaaaaactcatt
ctttcgcatcaagaagtcgagaaagtctttggcgaagtcggaggaatgattcaaaggaca
ggagcgactgatgggaatcttgtagacagcgaagtcaatgttggaactatttatgtcacc
ttaaaagataaaaaagaaagggtactttctcaaaggattttgatggacaccttaagagaa
gaattaaataagcttaaggatcttcgggctaccccacaagatctttccattcgaggattt
accactgggaggggatttcctatcgaattaactattcgtggggaagactacaaagtgctg
gaaaaaatagtacaggaagacatcgaagaaatgaaaaaaagcggctattttgttgatctg
gacacagactttagagatggaatgcctgaagtcagagtctatcccgataggtttgcagca
aatgcttgttcgattcccattcagaacattgctaatacagtagcgatcgccattggaggc
atcgcccaaggacaattcactaatggagaaagacggtatgatatccggataaggttacgg
ggcgatgaaagagtaggaccagaagatatcgcccggttggggatccgaaccaataccaat
gagttcatgcccataacttccgtagctaagcttcagactgtccaaacctatcaaacactg
acaagaaaaatgcgagaaagagcaattactatctttgcgaatgttgcttctggaaaatcc
caggctcaagccttggtagtggctaaaaagatatgcagcaaaaatcttcccaaaggctat
agactttttctgagtggtggagctgcctccttcgaggaaacattccaaagccttgtcttc
gctatttgggttggcgttgtcatcgcctacatggttttagcctcccagtttaacagtttt
gtccatcctttttctgtgctccttgccttaccatttagtttgagtggggctctgttggct
ctatggtttactcaccaatccatcaacctttacagtatgattggccttgttttgttaatg
ggtattgccaagaaaaattcgattcttttggttgagtttacaaatcagcttaggtataaa
gggctctctattaaagaggccatattagaagcggccccaattcggctgagacctatcctt
atgacttcgatggcgacgattgctgccgccatccctccggctcttgccttaggccctggg
gctgaaagccgtatccccatggcgattaccttacttggcggcattgctgtctcaacggta
tttacgttgtttgttgtgcctgcagcttatcttttactttctcgttttgaaaagtctagg
ccctttttgatccagcctcagactgctcctgttggaaaagaagaagaaagtttagtagag
aaaaaggattaa

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