Microtus fortis (reed vole): 126492018
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Entry
126492018 CDS
T08493
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3 isoform X1
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
mfot
Microtus fortis (reed vole)
Pathway
mfot01521
EGFR tyrosine kinase inhibitor resistance
mfot04010
MAPK signaling pathway
mfot04012
ErbB signaling pathway
mfot04020
Calcium signaling pathway
mfot04151
PI3K-Akt signaling pathway
mfot05205
Proteoglycans in cancer
mfot05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mfot00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
126492018
04012 ErbB signaling pathway
126492018
04020 Calcium signaling pathway
126492018
04151 PI3K-Akt signaling pathway
126492018
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
126492018
05205 Proteoglycans in cancer
126492018
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
126492018
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mfot01001
]
126492018
Enzymes [BR:
mfot01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
126492018
Protein kinases [BR:
mfot01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
126492018
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
TM_ErbB1
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
126492018
NCBI-ProteinID:
XP_049984067
LinkDB
All DBs
Position
Unknown
AA seq
1337 aa
AA seq
DB search
MKATLQVLGFLLSLARGSEMGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYDRCEVVMGN
LEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVMLN
YNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWSDIVRVRGADIVVKNNGKN
CPPCHEACKGRCWGPGPEDCQILTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQDTD
CFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCV
RACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLD
FLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMQNFSVFSNLTTIGGRS
LYNRGFSLLIMKNLNVTSLGLRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPPEDRL
DIKYNRPRRDCVAEGKVCDPLCSSGGCWGPGPAQCLSCRNYSREGVCVTHCHFLEGEPRE
FAQEGECFSCHPECLPMEGISTCNGSGSDACARCAHFRDGPHCVNSCPNGILGAKGPIYK
YPDAQNECRPCHENCTQGCKGPELQDCLGQTEVLMSKTHLAMAGMVGLPVALLILGGSFL
YWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKEPELRKLKVLGSGVFGTVH
KGIWIPEGESIKIPVCIKVIEDKSGRQSFQSVTDHMLAIGSLDHAHIVRLLGLCPGSSLQ
LVTQYLPLGSLLDYVRQHRAALGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVLLKS
PSQVQVADFGVADLLPPEDKQLLHSEAKTPIKWMALECIHFGKYTHQSDVWSYGVTVWEL
MTFGAEPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANE
FTRMARDPPRYLVIKRESGPGIPPGAEPSALTNKELEEVELEPELDLDLDLEAEEDSLVT
TLGSALSLPVGTLTRPRGSQSLLSPSSGYMPMNQNNLGEACLDSAVLGGSEQCPRPISLH
PIPRGRLTSESSEGHVTGSEAELQDKVLMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTP
VSPPGLEEEDANGYVMPDTHLKGTSSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRKRR
NSPPRPPRPGSLEELGYEYMDVGSELSASLGSTQSCPLHPMAIVPSAGTTPDEDYEYMNR
RRGVGGAGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVRYARLKTLRSLEATDSAFDN
PDYWHSRLFPKANAQRT
NT seq
4014 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcgactctgcaggtgctgggcttccttctcagcctggcccggggttccgagatg
ggcaactctcaggcagtgtgtcctgggacactgaatggcctgagcgtgacgggtgacgcg
gagaatcagtaccagacgttgtacaagctctacgaccggtgtgaggtggtgatgggcaac
ctggagattgtgctcacggggcacaacgctgacctctccttcctgcagtggatccgagaa
gtgacaggctatgtcctcgtggcaatgaatgaattctctacactacccttgcctaacctc
cgagtggtccggggaacccaggtgtatgacgggaagtttgccatctttgtcatgttgaat
tacaacaccaactccagccatgccctacgccagctccgcttcactcagctaactgagatt
ctgtcggggggcgtttatatcgagaagaatgacaaactttgccatatggatacaattgat
tggagtgacatcgtgagggtccgaggggccgacatcgtggtgaagaacaacgggaaaaac
tgtccaccctgtcatgaggcctgcaagggacgatgctgggggcctggaccagaagactgc
cagatattgaccaagaccatctgtgcccctcagtgtaacggtcattgctttgggcccaac
cccaaccagtgctgccatgacgagtgtgcagggggctgctctggaccccaggacacggat
tgctttgcctgccgacacttcaatgacagtggggcctgtgtgcctcgctgtccacaacct
cttgtgtacaacaagctaacgttccagcttgagcccaacccccacaccaagtatcagtac
ggaggggtctgcgttgccagctgtccccataactttgtggttgatcagacatcttgtgtc
agggcctgccctcctgacaagatggaagtagataaaaatggactcaagatatgtgagcct
tgtggaggattgtgcccaaaagcctgtgaggggacaggctctggaagccgctaccagact
gtggactctagcaacatcgatgggtttgtgaactgcaccaagatcctgggcaacctggac
ttccttatcactggcctcaacggagacccctggcacaagatccctgctctggacccggag
aagctcaatgttttcaggacagtacgggagatcacagggtacctgaacatccagtcctgg
cccccacacatgcagaacttcagtgttttctccaacctgacaaccatcgggggaagaagc
ctctacaaccggggcttctccttgctgatcatgaagaacttgaacgtcacctcgctgggc
ctccggtccctgaaggaaatcagtgctgggcgtgtctacatcagtgctaatcagcagctc
tgctaccaccactctctcaactggacgaggctgcttcggggccctccggaagacagactc
gacatcaagtataaccggcctcgaagagactgtgtggcagagggtaaagtgtgtgacccg
ctctgctcctctgggggatgctggggcccaggccctgctcagtgcctgtcttgtcgaaac
tacagccgagaaggcgtctgtgtgactcactgccactttctggaaggggaacctcgtgag
tttgcccaggagggcgaatgtttctcctgccaccccgaatgcctacccatggagggcatc
agcacgtgcaatggctcgggctctgacgcctgtgctcgctgtgcccatttccgtgacggc
ccccactgtgtgaacagctgccccaatgggatcctaggtgccaagggtccaatctacaag
tatccagatgctcagaatgaatgtcggccctgccacgagaactgcacccaggggtgtaag
ggaccagaactacaagattgtttaggccaaacagaggtattaatgagcaaaacccatctg
gccatggctgggatggtcggactgcccgtggctcttctgattctgggaggctcttttctc
tattggcgtggacgcaggattcagaataagagggctatgaggcgctacctggaacggggt
gagagcatcgagcctctggaccccagcgagaaggcaaacaaagtcttggccagaatcttc
aaagagccagagctgaggaagcttaaagtgctgggttctggtgtctttggaactgtacac
aaggggatttggatccctgagggtgaatccatcaagattccagtctgcattaaagtcatc
gaggacaagagtgggcggcaaagtttccagtctgtgactgaccatatgctggccatcggt
agcctagaccacgcccacatcgtgcggctcctgggactgtgcccaggatcatcactgcag
ctagtcactcagtacttgcctctgggctccctccttgactacgtgagacagcaccgcgca
gccctgggaccacagctgctgctcaactggggagtacaaattgccaagggtatgtattac
ctcgaggaacacagcatggtgcacagggacctggcgctccgcaatgtgctgctcaagtca
cctagtcaggtgcaggtggccgacttcggtgtggctgacctgctgccacctgaagacaag
cagttactacacagtgaggccaagactcctattaagtggatggccctcgagtgtatccac
ttcgggaaatacacacaccagagtgatgtctggagttacggtgtcaccgtctgggagttg
atgacttttggggcagagccctatgcggggctgagactggctgagataccagacctgctg
gagaagggcgagcggctggcacagcctcagatctgcaccattgacgtctacatggtcatg
gtcaagtgctggatgattgatgagaatattcgcccgacctttaaagagctagccaatgag
ttcaccaggatggcccgtgacccaccgcgatatctggtgataaagagagagagtgggcct
ggaatacctcctggggcagaaccctctgctctcacaaacaaagagctggaggaagtagaa
ctggagcctgaactggacctcgacctagacctggaggcagaggaggacagcctggtcacc
acactgggttctgccctcagcttaccagtgggaacacttacccggccacgtgggagccag
agtcttttaagcccctcgtctggatacatgcccatgaaccagaataatctcggggaggct
tgtctggattctgcagttttggggggtagtgaacagtgccctcgtcccatctctctgcac
ccaatcccacggggacgtctgacatcagagtcatcagagggccatgtgacaggctctgag
gctgaactccaggataaagtattgatgtgtagaagccggagccgaagtcggagccctcgg
ccacgtggagacagtgcctaccattcccagcgacacagcctgctgactcctgtcacccca
gtgtccccaccagggttagaggaagaggatgccaatggctatgtcatgccagatacacac
ctcaaaggtacatcctcctcccgggaaggtacgctttcttcagtaggcctcagttctgtg
ctgggtaccgaagaggaagacgaagatgaggagtatgagtacatgaaccggaagagaagg
aacagtccaccacggccccctaggcccggttcccttgaggagctgggttacgagtacatg
gatgtgggctcagagctcagtgcctctctgggcagtacgcagagctgcccactgcatcct
atggccatcgtgccatccgctggtacaactccagatgaggactacgagtatatgaaccgc
aggcgtggtgtaggtggtgccgggggtgattacgccgccatgggggcctgcccagcagcg
gaacaaggctatgaggagatgcgagccttccaggggcctggacatcatgccccccatgtt
cgttatgcccgcctcaaaactctgcgcagtttagaagccactgactctgcctttgacaac
cctgactactggcatagcaggcttttccccaaggctaatgcccagagaacttaa
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integrated database retrieval system
