Alexandromys fortis (reed vole): 126498321 Help Entry 126498321         CDS       T08493                                  Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism mfot  Alexandromys fortis (reed vole) Pathway mfot04022   cGMP-PKG signaling pathway mfot04068   FoxO signaling pathway mfot04081   Hormone signaling mfot04140   Autophagy - animal mfot04152   AMPK signaling pathway mfot04211   Longevity regulating pathway mfot04213   Longevity regulating pathway - multiple species mfot04910   Insulin signaling pathway mfot04920   Adipocytokine signaling pathway mfot04923   Regulation of lipolysis in adipocytes mfot04930   Type II diabetes mellitus mfot04931   Insulin resistance mfot04932   Non-alcoholic fatty liver disease mfot04935   Growth hormone synthesis, secretion and action mfot05010   Alzheimer disease mfot05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:mfot00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     126498321    04022 cGMP-PKG signaling pathway     126498321    04152 AMPK signaling pathway     126498321   09133 Signaling molecules and interaction    04081 Hormone signaling     126498321  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     126498321  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     126498321    04923 Regulation of lipolysis in adipocytes     126498321    04920 Adipocytokine signaling pathway     126498321    04935 Growth hormone synthesis, secretion and action     126498321   09149 Aging    04211 Longevity regulating pathway     126498321    04213 Longevity regulating pathway - multiple species     126498321  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     126498321   09164 Neurodegenerative disease    05010 Alzheimer disease     126498321   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     126498321    04932 Non-alcoholic fatty liver disease     126498321    04931 Insulin resistance     126498321 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  126498321 NCBI-ProteinID:  XP_049992818 LinkDB All DBs Position Unknown AA seq 1323 aa AA seqDB search MASAPLPGAPAPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDDA AAAGGSPPLPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRSGDGGSGTAATGGSCSASLPGVLGGSAGAAGSD DNYGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRV RTASEGDGGAAAGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSGGCGGRPSKVTLAPA GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLPHPLHHPQGQRP SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGY MSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR ATFSGSSGRLCPSFPVSSPKVAYHPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAAL RSVGPSSCKSDDYMPMSPTSVSAPKQILQPPSGAAVPAPPSGAGRTFPVNGGSYKASSPA ESSPEDSGYMRMWCGSKLSMENTDPKLLPNGDYLNMSPSEAGTAGTPPDFFSAALRGGGE GLKGVPGHCYSSLPRSYKAPYCSGDSDQYVLMSSPVGRILEEERLEPQPTSGTSQLAGTF GAAGGGHTQPHHSAVPSSMRPSGGSGRPEGFLGQRCRAVRPTRLSLEGLQTLPSMQEYPL PSEPKSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDS RQRSPLSDYMNLDFSSPKSPKPVAHSGDTVGSMDGLLSPEVSSPHPPLPPRPSASPSSLQ QPLPPAPGELYRLPPASVATAQGPTAGSSTPSEPGDNGDYTEMAFGVAATPPQPIAAPPK PEGARVTSPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRRHSSETF SSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSCILGGSDEAPTSPGQAQPSLAVP PAPQARPWNPGQPGALIGCPGGGSSPMRRETSVGFQNGLNYIAIDVRDEQGSLPPSQPQH PQPGDKSSWGRTRSLGGLLSTVGSTGTGGVCGGPGPGALPSASTYASIDFLSHHLKEATV VKE NT seq 3972 nt NT seq  +upstreamnt  +downstreamnt atggctagcgcgcccctacccggggcccccgcgccggcgggcggggatggcccgaacctc aataacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcggccccggcacgggcggcgacgatgca gccgcggctggggggtcgccgccgctgccaccgaggctggagtactatgagagcgagaag aagtggaggagcaaggcgggcgcgccgaagcgagtgatcgcgctagactgctgcctgaac atcaacaagcgcgcggacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggcagcggagaacgagcaggagcaagagggctggtaccgcgcgctcacc gacttggtcagcgagggtcgctctggcgatgggggctcgggcaccgcggccaccggcggg tcctgcagtgcctctctcccgggcgtgctgggcggctcggcgggtgccgctggctccgat gacaactacgggctcgtgacgcccgccacggcagtctaccgtgaggtgtggcaggtgaac ctgaagcccaagggcctgggtcagagcaaaaacctgactggtgtataccgtctatgtctg tctgcgcgcaccatcggcttcgtgaagctcaattgcgaacagccgtcggtgacactgcag cttatgaacattcgccgctgcggccactcagacagcttcttcttcatcgaagtgggccgc tcggccgtcaccggccccggcgagctgtggatgcaagccgacgactcggtggtggcgcag aacatccacgagaccatcctggaggccatgaaggcgctcaaggagctctttgagttccgg ccccgcagcaagagtcagtcgtccgggtcgtcggccacgcaccccatcagtgtgccgggc gcgcgccgccaccaccacctggtcaacctgccccctagccagaccggcctggtgcgccgc tcacgcaccgacagcctggcggccaccccgccagcagccaagtgcacctcatgtcgggtc cgtacggccagcgagggcgatggcggcgcggcagccggggccgggacagcgggaggcagg ccgatgtcggtggccgggagccccctgagtcctgggccggtgcgcgcgcccctgagtcgc tcgcacaccctgagcggcggctgcggaggccgcccgagcaaagtgacgctggcgccggca gggggcgccctgcaacacagccgttccatgtccatgcccgtggcgcactcaccgcccgct gccaccagccccggcagcctatcctccagcagtgggcatggctcgggctcctacccgctg cctccaggcccccacccgcatctgcctcatccgctgcaccacccccaaggccagcgtccg tccagcggcagtgcctctgcctccggctcccccagtgaccctggttttatgtcccttgat gagtatggctccagccctggcgacctgagggccttcagtagccacaggagcaacacgccc gagtcaatcgcggagaccccgccagccagggacggcagtgggggcgagctctatgggtac atgagcatggatagacccctgagccactgtggccgcccttaccgtagggtctctggggat ggggcccaggacctggacagagggctgaggaagaggacttattccttgaccacacctgcc cgacagcggccagtaccccagccttcctctgcctcccttgatgagtatactctcatgcgg gccaccttctctggcagttcaggtcgcctctgcccatccttccccgtgtcttctcccaaa gtggcctatcacccttacccagaggactatggagacattgagattggctcccacaagagt tccagcagtaacctgggggcagatgatggttacatgcccatgacccctggggctgccctc aggagtgttggccccagtagctgcaagagtgatgactacatgcccatgagccccaccagc gtgtctgcccccaagcagatcctgcagccaccctcgggagctgcagtgccagcaccccct tcaggggcaggcaggaccttccccgtgaacggaggcagctacaaagccagctccccagcc gagagctctccggaggatagcgggtacatgcgaatgtggtgtggctccaagctgtctatg gagaacacagacccaaagctgctccccaacggggactacctcaacatgtcccccagcgag gctggcaccgcgggcacgccacccgacttcttctcagcagctttgcgtggagggggagag ggcctcaagggtgtgcctggacactgctacagctctctgccccgctcttacaaggccccc tattgtagtggggacagtgaccaatatgtgctcatgagctcccctgtggggcgaatcttg gaagaggagaggctggaaccccagcccacctctggaacctcccagttggctggcaccttt ggggcagctgggggtggccatacccagcctcaccactcagcagtgccttcctccatgagg ccaagtggtggcagtggccgccctgagggcttcctgggccagcgctgtcgggcagtgcga cccacgcgcctgtcgctggagggactgcagacccttcccagcatgcaagagtacccttta ccctcggagcccaaaagccctggcgagtatatcaacattgactttggtgaggcgggtgcc cgtctgtccccgcctgcccccccactgctggcatcagcggcttcatcctcttcattgctt tcagccagtagtcctgcttcatccctgggttcaggtaccccaggcaccagcagtgacagc cggcagcgctccccgctctctgactatatgaacttggacttcagttctcccaagtcccct aaacctgtcgcccatagtggagacacagtaggctccatggatggccttctctccccagag gtctcatctccacacccacctctgcccccacgtccttctgcctccccctcttccctgcag cagcctctgccccctgccccaggagagctctaccgcctgcctccagcatcagttgccact gcccagggccccactgctggctcctcaacaccctcagagcctggggataatggtgactat accgagatggcctttggtgtggctgctaccccgccacaacctatcgcagcgcccccaaag ccagaaggtgcccgagtgaccagtcccacatctggcttgaagcgcctaagtctcatggat caagtgtctggggtggaggcctttcttcaagtcagccagccccctgatccccaccggggt gccaaggtcatccgtgcagacccacagggggggcggcgtcgccacagctcagagaccttc tcctccaccaccacagtcaccccagtgtccccctccttcgcccacaactctaagcgccac aattcggcctctgtggaaaacgtctctctcaggaaaagcagcgaaggtagctgcatcctg ggaggaagtgatgaggcacccacatccccaggacaggcacagccatcgttggctgtgcca ccagccccgcaggctaggccatggaacccaggtcaacctggggctttgattggctgtcct ggtggcggcagttctcccatgcgcagagagacctctgtgggtttccagaacggcctcaac tacatcgccattgacgtgagggatgagcaggggtccctgccgccatctcagccgcagcac ccacagcctggagacaagagttcctggggccggacccgtagccttgggggacttctcagc accgtgggaagcactggcaccggcggggtgtgtggaggcccaggccctggagccttgccc tctgccagcacctacgcaagcattgacttcttgtcccaccacttgaaggaagccacagtc gtgaaagagtga

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