KEGG T08493: 126511195

Alexandromys fortis (reed vole): 126511195

Entry

126511195         CDS       T08493

Name

(RefSeq) 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform X1

K13373

17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]

Organism

mfot Alexandromys fortis (reed vole)

Pathway

mfot00100

Steroid biosynthesis

mfot00140

Steroid hormone biosynthesis

mfot01100

Metabolic pathways

mfot04913

Ovarian steroidogenesis

Module

mfot_M00101

Cholesterol biosynthesis, FPP => cholesterol

Brite

KEGG Orthology (KO) [BR:mfot00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    126511195
   00140 Steroid hormone biosynthesis
    126511195
09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    126511195
Enzymes [BR:mfot01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     126511195
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     126511195

SSDB

Motif

Pfam:

adh_short adh_short_C2 KR Epimerase GDP_Man_Dehyd NAD_binding_10 Eno-Rase_NADH_b Sacchrp_dh_NADP

Other DBs

NCBI-GeneID:

126511195

NCBI-ProteinID:

XP_050014167

LinkDB

Position

Unknown

AA seq 334 aa
MRKVVLITGASSGIGLALCSRLLAKDDELHLCLACRNLSKAGAVRDALLASHPSAQVSIV
QMDVSSLRSVVQGAKEVKQKFQRLDYLYLNAGIMPNPQLNFKAFFLGIFSRNVVHMFSTA
EGLLTQNDKVTADGFQEVFETNLFGHFILIRELEPLLCHSDSPSQLIWTSSRNAKKSNFS
LEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVICPGVVLTNLTYGILPPFVW
TLLLPLLWLIRFFANAFTLTPYNGAEALVWLFHQKPESLNPLTKYLSSTTGFGTNYVKDQ
KMDIDEDTAEKFYQTLLELEKRVRITMEKSDHPS

NT seq 1005 nt +upstreamnt +downstreamnt
atgcggaaggtggttttgatcaccggggcgagcagtggcattgggctggccctctgcagt
cggctgctggcaaaagacgacgagcttcacctgtgtttggcgtgtaggaacctgagcaaa
gccggagccgttcgtgatgccctgctggcctctcacccctccgcccaagtcagcattgtg
cagatggatgtcagcagcctgcggtcggtggtccagggtgcaaaggaagtcaagcaaaag
tttcaaagattagactacttatatctgaatgctgggatcatgcctaatccccagctaaat
ttcaaagcgtttttcttgggcatcttttcaagaaatgtggttcatatgttctccacagcg
gaaggactgttgacccagaatgacaaggtcactgctgatgggttccaggaggtgtttgaa
accaatctctttggccactttatcctgatccgggaactggaaccccttctctgccacagc
gacagcccctcccagctcatctggacctcttctcgtaatgccaagaaatctaacttcagc
cttgaggatatccagcacagcaaaggcccggaaccctacagctcctccaaatacgctact
gaccttctgaatgtggctttgaacaggaatttcaaccagaagggtctgtattccagtgtg
atttgcccaggcgtagtactgaccaatctgacatacggaattctgccgccctttgtgtgg
acattgctcttgccgctgttatggctgattcgcttttttgcaaacgctttcactctgaca
ccgtacaatggagcagaagcgctggtgtggcttttccaccaaaaacctgagtctctcaac
cctctgaccaaatacctgagctccaccacaggcttcgggactaattacgtcaaggaccaa
aagatggacatagacgaagacaccgccgaaaaattttatcaaaccttattggaactggaa
aaacgcgttaggatcaccatggaaaaatcggatcaccccagctga

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