Alexandromys fortis (reed vole): 126511842 Help Entry 126511842         CDS       T08493                                  Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism mfot  Alexandromys fortis (reed vole) Pathway mfot01524   Platinum drug resistance mfot04115   p53 signaling pathway mfot04210   Apoptosis mfot04215   Apoptosis - multiple species mfot04217   Necroptosis mfot04620   Toll-like receptor signaling pathway mfot04621   NOD-like receptor signaling pathway mfot04622   RIG-I-like receptor signaling pathway mfot04623   Cytosolic DNA-sensing pathway mfot04625   C-type lectin receptor signaling pathway mfot04657   IL-17 signaling pathway mfot04668   TNF signaling pathway mfot04932   Non-alcoholic fatty liver disease mfot04936   Alcoholic liver disease mfot05010   Alzheimer disease mfot05016   Huntington disease mfot05022   Pathways of neurodegeneration - multiple diseases mfot05132   Salmonella infection mfot05134   Legionellosis mfot05142   Chagas disease mfot05145   Toxoplasmosis mfot05152   Tuberculosis mfot05160   Hepatitis C mfot05161   Hepatitis B mfot05162   Measles mfot05163   Human cytomegalovirus infection mfot05164   Influenza A mfot05165   Human papillomavirus infection mfot05167   Kaposi sarcoma-associated herpesvirus infection mfot05168   Herpes simplex virus 1 infection mfot05169   Epstein-Barr virus infection mfot05170   Human immunodeficiency virus 1 infection mfot05200   Pathways in cancer mfot05203   Viral carcinogenesis mfot05416   Viral myocarditis mfot05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mfot00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     126511842  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     126511842    04215 Apoptosis - multiple species     126511842    04217 Necroptosis     126511842    04115 p53 signaling pathway     126511842  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     126511842    04621 NOD-like receptor signaling pathway     126511842    04622 RIG-I-like receptor signaling pathway     126511842    04623 Cytosolic DNA-sensing pathway     126511842    04625 C-type lectin receptor signaling pathway     126511842    04657 IL-17 signaling pathway     126511842  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     126511842    05203 Viral carcinogenesis     126511842   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     126511842    05161 Hepatitis B     126511842    05160 Hepatitis C     126511842    05164 Influenza A     126511842    05162 Measles     126511842    05168 Herpes simplex virus 1 infection     126511842    05163 Human cytomegalovirus infection     126511842    05167 Kaposi sarcoma-associated herpesvirus infection     126511842    05169 Epstein-Barr virus infection     126511842    05165 Human papillomavirus infection     126511842   09171 Infectious disease: bacterial    05132 Salmonella infection     126511842    05134 Legionellosis     126511842    05152 Tuberculosis     126511842   09174 Infectious disease: parasitic    05145 Toxoplasmosis     126511842    05142 Chagas disease     126511842   09164 Neurodegenerative disease    05010 Alzheimer disease     126511842    05016 Huntington disease     126511842    05022 Pathways of neurodegeneration - multiple diseases     126511842   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     126511842    05416 Viral myocarditis     126511842   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     126511842    04932 Non-alcoholic fatty liver disease     126511842   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     126511842  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:mfot01002]     126511842 Enzymes [BR:mfot01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      126511842 Peptidases and inhibitors [BR:mfot01002]  Cysteine peptidases   Family C14: caspase family    126511842 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  126511842 NCBI-ProteinID:  XP_050015246 LinkDB All DBs Position Unknown AA seq 481 aa AA seqDB search MDFNSCLYKIAEQLCSSEVAALKFLCLDYIPQKKQEPINDALMLFQGLQEKEMLEEGNLS FLKELLFLICRLDLLTHDLNSSKDEMKKELYDLDKAQVSAYRVMLFKLSEHVSDLELKEF KFFLERKIPKCKLHDNASLLDVFVEMEKRLILGEDNLDSLKSIFEHVNKSLLRYIEEFEE SNRERRMSLEYGAEASGSFSDGQSCITMQEMYDSLREEDIDSQVSDRIYQMKSKPRGYCL IVNNYNFSEARERVPRLRKMKDRKGTERDEDALTETFQKLHFEVVSHKDCTVSKIHAILR AFQRLDHESKDCFICCILSHGDKGIIYGTDGKEASIRELTSYFTGSNCPSLAGKPKVFFI QACQGDSFHKAVPVETDSERDNYLDMDSSSQKNYIPDEADFLLGMATVKYCVSYREPMRG SWYIQSLCESLRERCPLGDDILSILTGVNYDVSNKDDRRNMGKQMPQPIFTLRKKLFFPL N NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atggatttcaacagctgcctttataaaattgccgaacagctgtgcagtagtgaagtggcc gccctcaagtttctgtgtttggactacataccacagaagaaacaggagcccatcaacgat gccctgatgctctttcaggggctgcaggagaaggaaatgttggaggaaggcaatctgtcc ttcctgaaggagttgcttttcctcatctgtcggctggacctgctgacccacgacctaaac agcagtaaggatgagatgaagaaagagctgtatgatctagacaaagctcaggtttctgcc tacagggtaatgctctttaagctctcagaacacgtgagtgatttggagttgaaagagttt aagtttttcttggaaaggaagatccccaaatgtaagctgcacgataacgcgagcctgctg gatgtttttgtggaaatggagaagaggctcatcctaggggaagacaacttggacagcctg aagtcaatctttgaacatgtcaacaaaagtctgctgcggtacatcgaagagtttgaagaa tcaaacagagagagaagaatgagcctggaatacggggcagaggcgtcaggttcattttcg gatggacagagctgcatcacaatgcaggaaatgtatgactccctaagagaagaagacatc gactcccaggtatcagatagaatatatcaaatgaagagcaaacctcgcggatactgtctg atcgtcaacaattacaatttcagcgaggcgcgtgagagagtacccagactccgcaagatg aaggacaggaagggaacagaacgtgatgaagacgcgttgactgagacctttcaaaagctt cattttgaggtcgtgtctcacaaagactgcacagtcagtaagatccatgcgatcctaaga gccttccagagactggaccacgagagcaaagactgcttcatctgctgcatcctctcccac ggagacaagggcatcatctacggcaccgatgggaaggaagcctccatccgagagctgaca tcgtatttcactggttcaaattgtccttctctggctggaaaacccaaagtctttttcatt caggcttgtcaaggggatagcttccataaagctgtacctgttgagaccgactcggagagg gacaactacttagacatggattcatcatctcaaaagaactatattccagatgaggctgac tttctgctggggatggctactgtgaaatattgtgtttcctaccgagaacccatgcgcgga agctggtacatccagtcactttgcgagagcctgcgagaaagatgtcctctaggtgacgat attctcagcatcctgactggtgtaaactatgatgtgagcaataaagatgacaggaggaac atggggaaacagatgccccagcccatcttcacgctacggaagaagctgttcttccctctc aactga

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