Alexandromys fortis (reed vole): 126513995
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Entry
126513995 CDS
T08493
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
mfot
Alexandromys fortis (reed vole)
Pathway
mfot00590
Arachidonic acid metabolism
mfot01100
Metabolic pathways
mfot01523
Antifolate resistance
mfot04726
Serotonergic synapse
mfot04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
mfot00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
126513995
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
126513995
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
126513995
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
126513995
Enzymes [BR:
mfot01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
126513995
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
126513995
NCBI-ProteinID:
XP_050018598
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All DBs
Position
Unknown
AA seq
663 aa
AA seq
DB search
MGRYRVRVVTGAWLFSGSLNRVELWLVGAHREVKLELPLRPARGKEEEFDFDVPEDLGPL
QFVKLHKQHTVVDDAWFCNLITVQGPGTSAEAVFPCYRWVQGDGELSLPEGTARLAGDNA
LDVFQKHREKELKERQQAYCWATWKEGLPQTIAADCKDDLPLNMRFHEDKRLDFEWTLKA
GVLEMGLKRVYTLLRSWNRLEDFDQIFWGQKSALAEKVHRCWQDDELFGYQFLNGANPML
LRRSTSLPPRLVLPSGAEELQAQLEKELKNGSLFEVDFILLDGIPANVIRGEQQYLAAPL
VMLRMDPSGKLLPMAIQIQPPSPSSPVPTLFLPSDPPLAWLLAKIWVRSSDFQLQELQFH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQVVST
GGGGHVQLLTRAMAQMTYCSLCPPDDLANRGLLRIPSALYAQDAIQLWKVTARYVEGMVH
LFYQSDEIVRGDPELQAWCWEITEVGLCHAQDRGFPVSFQTRAQLCHFLTMCVFTCTSQH
AAINQGQLDWYGWVPNAPCTMRMPPPTNKEEVTMEMVMGSLPDIQKSCLQMTITWHLGRL
QPDMVPLGQHKEKYFSDPRTKTVLSRFQADLGNLEREIIARNEQLDLPYEYLKPSRIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcgtccgtgtggtcactggggcctggctcttctccggatccctcaac
cgagtggagctgtggctggttggggcgcatcgggaggtgaagctggagctaccgctgagg
cccgcgcggggcaaggaggaagagtttgacttcgatgttcctgaggacttggggccactg
cagtttgtgaagctgcacaaacagcacacagtggtggacgacgcctggttctgcaacctc
attacagttcaggggcccggaacaagtgcagaggcggtgtttccctgctaccgctgggtg
cagggagacggagaactgagcctgccagaggggactgcccgcctggcaggagacaatgcc
ttggatgtcttccagaagcatcgagaaaaggaactgaaggaaagacaacaggcctactgc
tgggccacctggaaggaaggcttaccccagaccatagccgcagactgtaaggacgaccta
cctctgaatatgagattccatgaggataagaggctggactttgaatggacgctgaaggca
ggggttctggaaatgggtctcaaacgtgtttacaccctcctgagaagctggaaccgtctg
gaagactttgatcagatcttctggggccagaagagtgccttggctgagaaggttcaccgg
tgctggcaggacgatgagctttttggctaccagttcctcaatggtgccaaccccatgctg
ttgagacgctctacctctctgccccccaggctggtactgccctctggggcagaggagctc
caagcgcagttggaaaaagaactaaagaatggttccctgtttgaagttgacttcattctg
ctggatgggattccagccaatgtgatccggggagagcagcagtacctggctgcccctctt
gtcatgctgaggatggatcctagtgggaagctgctgcccatggcgatccagattcagcct
cccagtcccagctccccagttccaacattgttcctgccctcagatcctccactggcctgg
ctcttggctaagatatgggtccgaagttcagatttccagctgcaggagctccagttccac
ttgctgaacactcatctggtggccgaggtcattgctgtcgccaccatgaggtgcctcccg
ggactgcaccctatcttcaagctcctagttccccacatccgttacactatggaaatcaac
acacgaagccggacccagctcatctcagatgggggaatatttgatcaggtagtgagcaca
ggtggagggggccatgttcagttgctcactcgggcaatggcccaaatgacttactgctcc
ctctgtcctcctgatgacctggccaaccgaggcctgctgagaatcccaagtgctctctat
gctcaggacgcaatacagctctggaaagtcactgccaggtacgtggaggggatggtccac
ctcttctaccagagtgatgagattgtgaggggagacccagagctgcaggcctggtgttgg
gagatcactgaggtgggactgtgccatgcccaggacagaggtttccctgtctccttccag
acccgggctcagctctgccatttccttacaatgtgtgtcttcacatgcacgtctcagcac
gccgccatcaaccagggccagctggactggtatggctgggtacccaatgctccgtgcacc
atgaggatgcctccgcccaccaacaaggaagaggtgactatggagatggtgatggggtcg
ctacctgacattcagaagtcctgtcttcaaatgaccatcacatggcatctgggtcgcctc
cagccagacatggtacctctaggacaacacaaagaaaaatatttctcagaccccaggacc
aaaactgtgctcagtcgatttcaagcagatctgggaaatttggaaagagagatcatagcc
cggaatgagcaactcgacctgccctatgaatacctcaagcccagccgcatagagaacagc
atcaccatctga
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