KEGG   Alexandromys fortis (reed vole): 126514348
Entry
126514348         CDS       T08493                                 
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X1
  KO
K06276  3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
Organism
mfot  Alexandromys fortis (reed vole)
Pathway
mfot01524  Platinum drug resistance
mfot03320  PPAR signaling pathway
mfot04068  FoxO signaling pathway
mfot04071  Sphingolipid signaling pathway
mfot04140  Autophagy - animal
mfot04150  mTOR signaling pathway
mfot04151  PI3K-Akt signaling pathway
mfot04152  AMPK signaling pathway
mfot04210  Apoptosis
mfot04360  Axon guidance
mfot04510  Focal adhesion
mfot04660  T cell receptor signaling pathway
mfot04664  Fc epsilon RI signaling pathway
mfot04722  Neurotrophin signaling pathway
mfot04910  Insulin signaling pathway
mfot04919  Thyroid hormone signaling pathway
mfot04931  Insulin resistance
mfot04960  Aldosterone-regulated sodium reabsorption
mfot05145  Toxoplasmosis
mfot05205  Proteoglycans in cancer
mfot05208  Chemical carcinogenesis - reactive oxygen species
mfot05213  Endometrial cancer
mfot05215  Prostate cancer
mfot05223  Non-small cell lung cancer
mfot05231  Choline metabolism in cancer
mfot05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mfot00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    126514348
   04071 Sphingolipid signaling pathway
    126514348
   04151 PI3K-Akt signaling pathway
    126514348
   04152 AMPK signaling pathway
    126514348
   04150 mTOR signaling pathway
    126514348
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    126514348
  09143 Cell growth and death
   04210 Apoptosis
    126514348
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126514348
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    126514348
   04664 Fc epsilon RI signaling pathway
    126514348
  09152 Endocrine system
   04910 Insulin signaling pathway
    126514348
   03320 PPAR signaling pathway
    126514348
   04919 Thyroid hormone signaling pathway
    126514348
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    126514348
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    126514348
  09158 Development and regeneration
   04360 Axon guidance
    126514348
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126514348
   05208 Chemical carcinogenesis - reactive oxygen species
    126514348
   05231 Choline metabolism in cancer
    126514348
  09162 Cancer: specific types
   05215 Prostate cancer
    126514348
   05213 Endometrial cancer
    126514348
   05223 Non-small cell lung cancer
    126514348
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    126514348
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126514348
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    126514348
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    126514348
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mfot01001]
    126514348
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mfot04131]
    126514348
Enzymes [BR:mfot01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     126514348
Protein kinases [BR:mfot01001]
 Serine/threonine kinases: AGC group
  PDK1 family
   126514348
Membrane trafficking [BR:mfot04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    126514348
SSDB
Motif
Pfam: Pkinase PH_3 PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 Haspin_kinase APH Kdo
Other DBs
NCBI-GeneID: 126514348
NCBI-ProteinID: XP_050019202
LinkDB
Position
Unknown
AA seq 559 aa
MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTESSSAPGMPSGVTRQGPTMDGTTAEAR
PNTNPLQQHPAQLPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRH
IIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSF
DETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQA
RANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKL
EYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYEPLKAHPFFESITWENLHQQTPPK
LTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDTSLPQRSGSNIEQYIH
DLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLL
LTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCR
KIQEVWRQRYQSHPDAAVQ
NT seq 1680 nt   +upstreamnt  +downstreamnt
atggccaggaccaccagccagctgtatgatgctgttcctattcagtccagtgtggtgcta
tgttcctgcccatccccatcaatggtgaggtcccagactgagtccagttcggcccctggc
atgcctagtggtgttaccaggcagggacccaccatggatggcaccacagccgaagcccga
ccaaataccaaccccttgcagcagcaccctgcccagctgccaccacagcctcgcaagaag
cggcctgaagacttcaagtttgggaaaatccttggcgagggctctttttcgacagttgtt
ctggcccgagaactggccacttccagagaatatgctattaaaattctggagaaacgtcat
attataaaagagaacaaagtcccgtacgtaactagagagagagatgtgatgtcacgcctg
gatcacccattctttgtgaaactttactttacatttcaggacgacgaaaagttgtatttt
ggccttagttatgccaaaaatggagaattacttaaatatatccgcaaaatcggttcattt
gatgaaacctgtacccgcttttacacggctgagattgtgtctgctttagagtacttgcac
ggaaagggcatcattcacagagaccttaaaccagaaaacattttgttaaatgaagacatg
cacatccagatcacagattttggaacagcaaaagtgttatccccagagagcaaacaagcc
agggccaactcatttgtaggaacagcacagtatgtttctccagagctgctcacagagaag
tcggcgtgtaagagttcagacctttgggctcttggatgtataatctatcagcttgtggca
ggacttccaccgttcagagccggaaatgaatatcttatatttcagaagattattaagctg
gaatatgatttcccagagaaattctttcctaaggcaagagatcttgtggaaaaactcttg
gttttagatgccacaaagcgtttaggctgtgaagagatggaagggtacgagcctctcaaa
gctcatccgttctttgagtccatcacatgggagaatctgcaccagcagacacctccaaaa
cttacagcttacttgccagccatgtcagaagatgatgaagactgctatggcaactatgac
aatctcctgagtcaatttggctgcatgcaggtgtcatcctcctcctcttcccactcccta
tctgcggtggataccagcctgccccagaggtcgggcagcaacatagagcagtacatccat
gatttggacactaactcttttgaactagacttacagttttcagaagatgaaaaaaggttg
ttattggaaaagcaagccggtggaaacccttggcaccagtttgtagaaaataatctaata
ttaaaaatgggcccggtggataagcgaaagggtttatttgcaagacgacggcagttatta
ctcacagaagggccacatttatattatgttgatcctgtcaacaaagtcttgaaaggtgaa
attccatggtcacaagaacttcgaccagaggccaagaattttaaaactttttttgtccac
acgcctaacaggacgtattacctgatggatccaagcgggaatgctcacaagtggtgcaga
aagatccaggaggtttggaggcagcggtaccagagccatccagatgctgctgtgcagtga

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