Mycolicibacterium frederiksbergense: EXE63_26480
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Entry
EXE63_26480 CDS
T10436
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mfre Mycolicibacterium frederiksbergense
Pathway
mfre00010
Glycolysis / Gluconeogenesis
mfre00020
Citrate cycle (TCA cycle)
mfre00620
Pyruvate metabolism
mfre00785
Lipoic acid metabolism
mfre01100
Metabolic pathways
mfre01110
Biosynthesis of secondary metabolites
mfre01120
Microbial metabolism in diverse environments
mfre01200
Carbon metabolism
mfre01210
2-Oxocarboxylic acid metabolism
Module
mfre_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mfre00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EXE63_26480 (aceE)
00020 Citrate cycle (TCA cycle)
EXE63_26480 (aceE)
00620 Pyruvate metabolism
EXE63_26480 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EXE63_26480 (aceE)
Enzymes [BR:
mfre01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EXE63_26480 (aceE)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QIV84031
UniProt:
A0A6H0SBS1
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All DBs
Position
complement(4839531..4842320)
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AA seq
929 aa
AA seq
DB search
MTTEFARQDLAQNSGTTGEPDRVRVIREGVASYLPDIDSEETAEWMESFDQLVERSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNSIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSASLYEVGFNHFFRGKSHPGGGDQIFIQGHASPGVYARAF
LEGRLSTDQLDGFRQEHSHAGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARYNHY
LNDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVVNCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVDPMTDKEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTIILAKT
IKGYTLGQHFEGRNATHQMKKLALEDLKAFRDVTRVPISDADLEKDPYLPPYYHPGPNAP
EIRYLLDRRRTLGGFLPERRTKSKALKLPPGDTYKALKKGSGKQPVATTMATVRTFKELL
RDKNIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDSELMLAYKESEIGQILH
EGINEAGSTASFTAVATSYATHNEPMIPIYIFYSMFGFQRTGDGFWAAADQMARGFVLGA
TAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEIAHIVESGLTRMYGENPENVF
FYITIYNEPYVQPAEPENFDPEGVLRGMYRFRAAPEKRSSTAQILASGVSMPEAIKAADM
LAEKWDVAADVWSVTSWGELNRDGVAVEKQRLRHPDQPAPTAYVTQVLADATGPVVAFSD
WMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLEALARDGEID
PSVAIAAAKEYQIDDVKAAGVSYADTGSA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgcgcgccaagacctggcccaaaactctggcaccacaggcgaaccc
gaccgggttcgcgtgatcagggagggcgttgcctcctatctgcccgatatcgattccgag
gagaccgcggagtggatggagtcgttcgaccagttggttgaacggtccggtcccgctcgg
gcgcgctacctgatgttgcgtctgctggaacgcgccggcgagcagcgtgtcgccattccc
gccttgacctccaccgactacgtcaacagcatccccaccgaactggagccctggtttccc
ggtgacgaggatgtcgaacgacgctaccgggcctggatccgctggaacgccgccatcatg
gtgcaccgcgcgcagcgcccgggagtcggtgtgggcggccacatttcgacgtacgcatcg
tcggcgtcgctgtacgaggtggggttcaaccacttcttccgcggcaagtcccaccccggt
ggtggcgatcagatcttcatccagggccacgcctcccccggcgtctacgcacgcgccttc
ctggaaggccggctgtcgaccgaccaactggacggtttccgccaggagcactcccatgcc
ggcggcggactgccgtcctatccgcacccgcggctgatgcccgacttctgggaattcccc
accgtgtcgatgggcctgggcccgatgaacgcgatctatcaggcgcgctacaaccattac
ctcaacgaccgcggcatcaaggacacctccgatcagcacgtgtgggcgttcctcggcgac
ggtgagatggacgaacccgaaagccgcggcctgatccaggtggccgccaacgaggcgctg
gacaacctgaccttcgtggtcaactgcaacctgcagcgcctggacggcccggtccgcggc
aacggcaagatcatccaggaactggaatcgttcttccgcggtgccggctggaacgtcatc
aaggtggtgtggggccgcgaatgggatgccctgttgcatgccgaccgcgacggcgcgctg
gtcaacctgatgaacaccacgcccgacggcgactaccagacctacaaggccaacgacggc
gcctacgtccgcgatcacttcttcggtcgggacccgcgcaccaaggcactggtggatccg
atgaccgacaaggagatctggaacctcaagcgcggcggccacgactaccgcaaggtgtac
gcggcctaccgggcggcgatggagcacaagggccagcccacgatcatcctggccaagacc
atcaagggctacacgctgggccagcacttcgagggccgcaacgccacgcaccagatgaaa
aagcttgccctggaagacctcaaggcgttccgcgatgtcacccgggtaccgatcagcgat
gccgatctggagaaggatccctatctgccgccgtactaccaccccgggcccaacgccccc
gagatccgctacctgctggaccggcggcgcaccctgggtgggttcctgcccgagcgccgc
accaagtccaaggcgctcaagctcccgcccggcgacacctacaaggccttgaagaagggt
tcgggcaagcaaccggtggccaccaccatggcgaccgtgcgtacgttcaaggaactgttg
cgcgacaagaacatcgggccgcgcatcgtgccgatcatcccggacgaggcccgcacgttc
gggatggactcgtggttcccgagcctgaagatctacaaccgcaacgggcagctctacacc
gcggtggactccgagctgatgctggcctacaaggaatccgagatcggccagatcctgcac
gagggcatcaacgaggccggctcgacggcatcgttcaccgcggtggccacctcgtacgcc
acgcacaacgagccgatgatcccgatctacatcttctattcgatgttcgggttccagcgc
accggtgacgggttctgggcggccgccgatcagatggcccgcggcttcgtgctgggcgcc
accgccggtcgcaccacgctgaccggcgagggactgcagcacgccgacgggcactcgctg
ctgctcgcctcgacgaacccggcggcggtcacctatgacccggcgttcgcctacgagatc
gcgcacatcgtcgagagtggcctcacgcggatgtacggggagaacccggagaacgtgttc
ttctacatcaccatctacaacgagccctacgtgcagcccgccgagccggagaacttcgat
cccgagggtgtgctgcgcgggatgtaccggttccgggccgccccggagaagcgcagcagc
accgcgcagatcctggcgtccggggtgtcgatgcccgaagccatcaaggccgcggacatg
ctggccgagaaatgggatgtcgccgccgacgtctggtcggtgaccagctggggcgagctc
aaccgcgacggtgtcgcggtggagaagcaacggctgcgccaccccgatcagcccgcaccg
acggcgtatgtcacccaggtgctcgccgatgccaccggaccggtcgtggcgttctcggac
tggatgcgtgcggtgcccgagcagatccggccctgggtgccgggcacctatgtgacgctg
gggaccgacgggttcggcttctccgacacccggccggcggcacgccgctacttcaacacc
gacgccgagtcggtggtggtggctgtattggaggcgctggcccgcgacggtgagatcgat
ccgtcggtggccatcgccgcggccaaggagtaccagatcgacgacgtgaaggccgccggc
gtctcctacgccgacaccggaagcgcctag
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