Mannheimia haemolytica USMARC_2286: N220_03275
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Entry
N220_03275 CDS
T02758
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mhal
Mannheimia haemolytica USMARC_2286
Pathway
mhal00270
Cysteine and methionine metabolism
mhal00450
Selenocompound metabolism
mhal00670
One carbon pool by folate
mhal01100
Metabolic pathways
mhal01110
Biosynthesis of secondary metabolites
mhal01230
Biosynthesis of amino acids
mhal04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mhal00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
N220_03275 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
N220_03275 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
N220_03275 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
N220_03275 (metH)
04980 Cobalamin transport and metabolism
N220_03275 (metH)
Enzymes [BR:
mhal01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
N220_03275 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
AGR74405
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Position
638925..642641
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AA seq
1238 aa
AA seq
DB search
MNTQHRTELLQNALTERILILDGAMGTMIQKYKLTESDFRGERFKNSTIDLKGNNDLLTL
TQPLLISAIHEKYLAAGADIIETNTFSATTIAQADYELESIAYELNLVGAKLARLAADKF
SIPEKPRFVAGILGPTNRTCSISPDVNDPGFRNITFMQLVEAYAEATRGLIEGGADLIMI
ETIFDTLNAKAAVFAIETVFDELGVKLPIMISGTITDASGRTLSGQTTEAFYNSLRHAKP
LTFGLNCALGPKELRPYVEMMSKISETFVSVHPNAGLPNAFGGYDLGAEEMATYIKEWAE
LGWLNIVGGCCGTTPEHIQAFAEATKGVAPRKLPEIPTAMRLSGLEPLTIDDNSLFVNVG
ERNNVTGSAKFKKLIKEEKFAEAIEIAISQVENGAQVIDVNMDEALLDSKKCMTRFLNIL
ATEPEAAKVPIMIDSSKWEVIEAGLQTVQGKPIVNSISLKEGEEKFIHQAKLCRRYGAAV
VVMAFDEVGQADTEERKVEICTRAYRILVDQLGFPPEDIIFDPNIFAIATGIEEHNNYGV
DFIQACERIKRDLPHAKISGGVSNVSFSFRGNNVVREAIHAVFLYYAIKAGMDMGIVNAG
QLAIYDDLDPELREAIEDAVLNHRHDTTDRLLEISEKYRGVKVESADESAAEWRNLPVAE
RLKHALVKGITTYIIEDTEEARQQFASPLEVIEGPLMAGMDVVGDLFGDGKMFLPQVVKS
ARVMKQSVAYLEPYINATKQKGSSNGKMVIATVKGDVHDIGKNIVSVVLQCNNFEVIDLG
VMVPADVIIETAIREKADLIGLSGLITPSLDEMEYFLGEMNRLKLDIPVLIGGATTSKEH
TAIKLYPKYNYPVVYTANASRCVTVCATLMNPEAKAEFWEKTKAEYEEIQRKFAVRKPLR
NGLSIEEARANRFDGFSGEWADYVPPTPKQTGIIEYKNVPIATLRKFIDWSPFFMLWGLM
GGYPDAFDYPEGGEEARRVYNDAQRVLDEFEQNGKLNPSGIMGIFPAVREGDDIAILNED
RTACIGKSYHLRQQSERGKNSKSPYNLCLSDFIADRESGQQDWFGMFAVCAGIEEHYLVE
SYKAAGDDYNAILLQAVGDRLAEAMAEYLHFELRTKVWGYTVEDEDNGRLIREEYIGIRP
APGYPSCPEHTEKQIIWDLLEVEQRIGMKLTESYAMWPAASVCGWYFTHPTSNYFTLGKI
DEDQVLDYAKRKGWDELTAKKWLSVAMKQDVKSQAENI
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atgaacacgcagcatagaaccgaattacttcaaaatgcccttaccgaacgcattcttatc
ttagacggtgcgatgggaacgatgatccaaaaatataaactaaccgaatctgatttccga
ggtgaacgttttaaaaacagtaccatcgatcttaaaggcaataacgacctactcacactc
acccagccactcctgatttctgctattcacgagaaatatttagccgccggtgcggatatt
atcgaaactaatacctttagtgcgacgaccattgctcaagcagattatgaacttgaaagt
attgcttatgagctgaatcttgtgggggcaaaacttgcccgtcttgccgccgataaattc
tccatccctgaaaaacctcgttttgttgccggtattcttgggccgactaaccgtacttgt
tcgatttcccctgatgttaatgaccccggtttccgtaacattacctttatgcaactggtg
gaagcctatgccgaggcaacccgtggtttgattgaaggtggggcggatctgattatgatc
gaaaccattttcgataccctgaatgccaaagcggcggtgtttgcaattgaaacggtgttt
gatgaactgggcgtgaaattgccgataatgatctccggcaccattaccgatgcctcaggg
cgaacgctgtcagggcagaccacggaggcgttttataactcgctccgccacgccaaaccg
ctgacgttcggcttgaactgtgcgctcgggccgaaggaactccgcccttatgtagagatg
atgtcgaaaatcagtgagacttttgtttcggttcacccgaatgccggcttgccaaacgct
tttggcgggtacgatttaggggcggaagagatggcgacttacatcaaagagtgggcagaa
ctcggctggctgaatattgtcggcggctgttgtggcaccacgccggagcatatccaagcc
tttgccgaagcaaccaaaggcgttgcgcctcgtaaattacctgaaattccaaccgctatg
cgtttgtcgggcttagaaccgctgacgattgacgataattcgctgtttgtgaatgtgggc
gaacgcaataacgtcaccggttcggcaaaatttaagaagctgattaaagaagaaaaattt
gcggaagcgattgaaattgccatcagccaagtggaaaacggggcgcaggtgattgacgtg
aatatggacgaggcgttgctcgattccaaaaaatgtatgacccgtttcctcaacattctt
gctaccgaacctgaggcggcaaaagtgccgattatgattgactcctcgaaatgggaggtg
atcgaggcgggcttgcaaacggtgcagggcaagccgatagtgaactccatttcactcaaa
gagggcgaagagaaatttattcaccaagccaaactctgccgccgctatggggctgcggtg
gtggtgatggcatttgacgaagtcgggcaagcggataccgaagaacgcaaggtagaaatt
tgtacccgagcttatcggattttggttgatcagctcggcttcccaccggaagacattatt
ttcgacccgaacatttttgcgattgccaccggtattgaagaacacaataactacggcgtg
gattttatccaagcctgtgagcggattaaacgagacttgccacacgccaaaatttccggc
ggggtgtcgaatgtctctttctctttccgaggcaacaatgtggtgcgtgaggctattcac
gccgtgttcctctactatgcgatcaaagccggaatggatatggggatcgtgaacgcaggg
cagttggcgatttatgacgacctcgaccctgaactgcgagaggcgattgaagatgcggtg
ctgaaccaccgtcatgacactaccgaccgcctgttggaaatttccgaaaaatatcggggc
gtaaaagtagaaagtgccgatgaaagtgccgccgagtggcgaaatttacctgtggcagag
cgtttaaaacacgccctcgtaaaaggcataacgacctacattattgaagataccgaagag
gctcgccagcaatttgcctctccgctggaagtgattgaagggccgctcatggcgggtatg
gacgtggtgggcgacctgttcggagacggcaaaatgttcctgccgcaagtggtgaaatcg
gctcgggtaatgaaacagtccgttgcctatttagagccgtacatcaacgccaccaagcag
aaaggatcgagcaacggcaaaatggtgatcgccaccgtgaaaggtgatgtacacgacatc
ggcaaaaacatcgttagcgtggtgttgcagtgcaataactttgaagtgatagacttaggc
gtgatggtgcctgccgatgtaattatcgaaactgctattcgggagaaagccgatctcatt
gggttaagcggactaattaccccatcgctggacgaaatggagtattttttaggtgaaatg
aaccgcttgaagctcgatattccggtgctgattggcggcgcaacgacctcaaaagagcat
acggcgatcaaactttatccgaaatataactaccccgtagtctataccgccaacgcttca
cgttgcgtaaccgtctgtgcgaccttgatgaaccctgaggcaaaagccgaattttgggaa
aaaaccaaagccgaatacgaagaaattcagcgtaaatttgccgttcgcaaaccacttcgc
aacggtttatctattgaggaggctcgagccaatcgttttgacggatttagtggcgaatgg
gcagactatgtgccgccaacgccaaaacagaccggcattatcgagtacaaaaatgtaccg
attgccaccctacgcaaatttatcgactggtcgccgttctttatgctctggggcttaatg
ggcggttatcctgatgcctttgattatccggaaggcggcgaagaggcacgccgtgtctat
aacgatgcccaacgggtgctggacgaatttgagcaaaacggcaagctcaacccaagtggg
attatgggcattttccctgccgtgcgtgagggcgatgatattgcaattttaaacgaagat
cgcaccgcttgtatcggcaaatcctaccacctccgccaacaatccgaacgaggcaaaaac
agcaaaagcccgtacaacctctgtttaagcgattttatcgccgaccgagaaagcggacaa
caagactggttcggaatgttcgccgtttgtgccggcattgaagaacactatttagttgaa
agctacaaagcggcaggcgatgactacaacgccattttgctccaagccgttggcgaccgc
ttggcagaagcaatggcggaatacctacactttgagctacgtaccaaagtctggggctac
accgtggaagacgaagacaacggacgcttaatccgtgaagaatacatcggcatccgccct
gcgcccggctacccaagctgcccggaacacaccgagaaacagataatttgggacttgtta
gaggtggaacaacgcatcggcatgaaactcaccgaaagctatgccatgtggccggcagca
agtgtctgcggctggtacttcacccaccctaccagcaactacttcactctcggcaagatt
gatgaagatcaggtgttggattacgccaaacgcaaaggctgggacgaactcacggcgaag
aaatggttaagtgtggcgatgaaacaagatgtcaagtcgcaggctgaaaacatttaa
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