KEGG   Mycobacterium heckeshornense: JMUB5695_00600
Entry
JMUB5695_00600    CDS       T07325                                 
Symbol
cyp51
Name
(GenBank) lanosterol 14-alpha demethylase
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
mhek  Mycobacterium heckeshornense
Pathway
mhek00100  Steroid biosynthesis
mhek01100  Metabolic pathways
mhek01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:mhek00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    JMUB5695_00600 (cyp51)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mhek00199]
    JMUB5695_00600 (cyp51)
Enzymes [BR:mhek01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     JMUB5695_00600 (cyp51)
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     JMUB5695_00600 (cyp51)
Cytochrome P450 [BR:mhek00199]
 Cytochrome P450, animal type
  CYP51 family
   JMUB5695_00600 (cyp51)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-ProteinID: BCQ07183
LinkDB
Position
complement(643986..645353)
AA seq 455 aa
MTSQGLKDVPRVSGGHEEHGHLEEFRTDPIGLMKRVRDECGDVGWFQLAGKQVVLLSGAQ
ANEFFFRASDDDLDQAEAYPFMTPIFGKGVVFDASPERRKEMLHNAALRGEQMKGHATTI
EGEVRRMIAGWGETGEIDLLDFFAELTIYTSSACLIGKKFRDELDGRFARLYHELERGTD
PLAYVDPYLPIESFRRRDQARKGLVALVQAIMDNRIANPPADKSDRDMLDVLITVKDEHG
NPRFSADEITGMFISMMFAGHHTSSGTAAWTLIELMRHPDIYAGVIKELDELYADGQPVS
FHALRQIPRLENVLKETLRLHPPLIILMRVAKGEFEVEGYPIHKGDLVAASPAVSNRIPE
DFPDPDEFVPQRYDEPRQEDLINRWTWIPFGAGRHRCVGAAFATMQIKAIFSVLLREYEF
EMTQPPESYRNDHSKMVVQLAQPAKVRYRRRNGGR
NT seq 1368 nt   +upstreamnt  +downstreamnt
gtgacaagtcaaggactaaaggatgttccgcgtgtctccggcggtcacgaggaacacggg
cacctagaggagttccgcaccgatccgatcgggctgatgaaacgggtccgcgacgaatgc
ggtgacgtcggctggttccagttggccggcaagcaggtggtgttgttgtcgggtgcgcag
gccaacgagttcttcttccgcgccagcgacgacgacctcgaccaggctgaggcgtacccg
ttcatgacaccgattttcggcaaaggtgtggttttcgacgccagccccgagcggcgaaag
gaaatgctgcacaacgcggcgctgcgcggcgagcagatgaaaggtcacgccaccaccatc
gaaggtgaagtgcgccggatgatcgccggctggggggaaaccggcgagatcgacctgttg
gacttcttcgccgagctgaccatctacacctcttcggcctgcttgatcggaaagaagttc
cgcgacgagctcgacgggcggttcgcccggctctaccacgagctggagcgcggcaccgac
ccgctggcctatgtcgacccgtacctgccgatcgaaagcttccgccggcgcgaccaggct
cgaaaaggattggtggcgctggtccaagcgatcatggacaaccggatcgccaacccgccg
gcagacaaaagcgaccgcgacatgctcgacgtgctgatcaccgtcaaagacgagcacggc
aatccccggttcagcgccgacgagatcaccggcatgttcatctcgatgatgttcgccggc
catcacaccagctcaggcaccgcggcgtggacgctgatcgagttgatgcgccaccctgac
atctacgccggcgtaatcaaggagctcgacgagctttacgccgatggtcagccggtgagt
ttccatgcgctgcgccagattccgcggctggagaacgtgctcaaggagacgctgcggttg
cacccgccgctgatcatcctgatgcgggtggccaagggcgagttcgaggtggaaggctat
cccatccacaagggtgacctggtggcggcatcgccggccgtctccaaccgcatcccggag
gacttcccggaccccgacgagttcgtaccgcaacgctacgacgagccgcgtcaggaagac
ctgatcaaccggtggacgtggattccgttcggcgccggtcggcatcgttgcgtaggagcc
gcgttcgccaccatgcagatcaaggctatcttctcggtgctgttgcgggaatacgagttc
gagatgacgcaaccgcccgaaagttaccgcaacgaccattccaagatggtggtgcagctg
gcccaaccggccaaggtgcgctaccgccgccgcaatggaggtcgatga

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