Mycolicibacter heraklionensis: K3U94_06735
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Entry
K3U94_06735 CDS
T07612
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mher
Mycolicibacter heraklionensis
Pathway
mher00020
Citrate cycle (TCA cycle)
mher00630
Glyoxylate and dicarboxylate metabolism
mher00785
Lipoic acid metabolism
mher01100
Metabolic pathways
mher01110
Biosynthesis of secondary metabolites
mher01120
Microbial metabolism in diverse environments
mher01200
Carbon metabolism
mher01210
2-Oxocarboxylic acid metabolism
Module
mher_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mher_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mher00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
K3U94_06735
00630 Glyoxylate and dicarboxylate metabolism
K3U94_06735
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K3U94_06735
Enzymes [BR:
mher01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
K3U94_06735
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
K3U94_06735
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
K3U94_06735
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
K3U94_06735
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QZA08963
UniProt:
A0A9X7WIS4
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Position
complement(1407558..1411265)
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AA seq
1235 aa
AA seq
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MSGISSPFGQNEWLVEEMYRKFREDPASVDPSWHEFLADYSPDAQRGDGAAAPAAPPAPP
AQPAPPAPAAPAPAAPAAAAPAPAAPAPAPAAKPTPSQAPAPLADDELQVLRGAAAAVVK
NMSTSLEVPTATSVRAVPAKLMIDNRIVINNQLKRTRGGKISFTHLLGYAIVQAVKQFPN
MNRHFAEVDGKPNAVTPAHTNLGLAIDLQGAGGKRSLVVAAIKGSESLRFAQFVDAYEDI
VRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASE
QRIAELGVGKVITLTSTYDHRIIQGAESGDFLRTVHEMLLSDAFWDEIFFELSIPYEPVR
WRTDNPDSVVDKNARVVELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVQSHGLTLWD
LDREFKVTGLPGSDIRKLREILSVLRDAYCRHVGVEYTHILEPEQQQWLQERIEVKHVKP
TVAQQKYILSKLNAAEAFESFLQTKYVGQKRFSLEGAETVIPMMDAAIDQCAEHGLDEVV
IGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPAEAHGSGDVKYHLGATGVYLQMFGDND
IQVSLTANPSHLEAVDPVLEGLVRARQDLLGRGALGTDEDPPFSVVPMMLHGDAAFAGQG
VVAETLNMALLPGYRVGGTIHIVVNNQIGFTTAPDYSRSSEYCTDVAKMIGAPIFHVNGD
DPEACDWVARLAVDFRQKFHKDVIIDMLCYRRRGHNEGDDPSMTNPYMYDVIGTKSGVRK
SYTEDLIGRGDISLKEAEDALRDYHGQLERVFNEIRELEKHAALPSESVESEQQVPRGLN
TAVDKAMLARIGDAFMTIPEGFTVHPRVLPVLERRREMAYEGKVDWAFGELLALGSLVAE
GKLIRLSGQDTRRGTFSQRHSVIIDQANGAEFSPLQLLATNADGTPTGGKFLVYDSPLSE
FAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHG
HEGQGPDHTSGRIERFLQLWAEGSMTIAVPSTPSNYFHLLRRHALDGIQRPLIVFTPKSM
LRNKAAISDIKDFTDVKFRSVLEEPTYEDGVGDRSKVTRVLLTSGKLYYELVARKAKDGR
DDIAIVRIEQLAPLPKRRLGDTLDRYPNAQQFFWVQEEPANQGAWPRFGLELPELLPEKL
TGIKRISRRAMSAPSSGSSKVHAVEQQEIIDSAFS
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
gtgagcggtatcagttcacccttcggtcagaacgagtggctagtcgaggagatgtaccgc
aaattccgcgaggatcccgcctcggtggacccgagctggcacgagttcctggccgactac
tcccccgacgcgcagcgcggtgacggtgcggctgcacccgcggccccgcccgctcccccg
gcgcaaccggctccccccgctcctgcggcacccgcccccgcagcaccggccgctgccgcc
ccggctcctgctgctccggcgccggccccggccgccaagcccaccccctcgcaagctccc
gcgccgctcgccgacgacgagctgcaggtgttgcgtggcgccgcggcagcagtggtcaag
aacatgtccacctccctggaggtgccgacggccaccagcgtgcgcgccgtgccggccaaa
ctgatgatcgacaaccgcatcgtcatcaacaaccagctcaagcggacccgcggcggcaag
atctcgttcacccacctgctgggttacgcgatcgtgcaggcggtcaagcagttccccaac
atgaaccggcatttcgccgaggtcgacggcaagccgaacgccgtcacgccggcccacacc
aacctgggactggccatcgacctgcagggcgccggcggcaagcggtccctggtggtggct
gccatcaagggctcggaatcgctgcgcttcgcgcagttcgtcgacgcctacgaagacatc
gtgcgtcgggcccgggacggcaagctcaccgccgaggacttcgccggcgtgacgatctcg
ctgaccaaccccggaaccatcggcaccgtgcactcggtgccccggctgatggccggccag
ggcgcgatcatcggcgtcggcgcaatggaatatcccgccgagttccaaggggccagcgaa
cagcgcatcgccgagctgggcgtcggcaaggtgatcaccctcacctcgacctatgaccac
cgcatcatccagggcgcggaatcgggcgacttcctgcgcaccgtgcacgagatgctgctg
tcggacgcgttctgggacgagatcttcttcgagctgtccatcccctacgagccggtgcgg
tggcgcacggacaacccggactcggtggtggacaagaacgcccgcgtcgtcgagctgatc
gccgcctaccgcaaccgcggccacctgatggccgacatcgacccgctgcgactggacaac
acccggttccgcagccaccccgacctggacgtgcagagccacggcctgacattgtgggac
ctggaccgggagttcaaagtcaccggcctgccgggcagcgatatccgtaagctgcgcgag
atcctgtcggtgctgcgcgacgcctactgccgccacgtgggcgtggagtacacccacatc
ctcgagcccgagcagcagcagtggctgcaggagcgcatcgaggtcaagcacgtcaaaccc
actgtggcgcagcagaagtacattctgagcaagctcaacgccgccgaggcgttcgaaagc
ttcctgcagaccaaatacgtcggccagaagcggttctccctcgaaggcgccgaaaccgtc
atcccgatgatggacgcggccatcgaccagtgcgccgagcacggcctcgacgaggtcgtc
atcgggatgccgcaccgcggccggctcaatgtgctggccaacatcgtcggcaagccctac
tcgcagatcttcaccgagttcgagggcaacctcaacccggccgaggcgcacggctccggc
gacgtcaagtaccacctgggcgccaccggggtgtacctgcagatgttcggcgacaacgac
attcaggtgtcgctgaccgccaacccgtcacacctggaggcggtggacccggtgctggag
ggcctggtccgggcccgccaggacctgctgggccgcggcgccctgggcaccgacgaagac
ccacccttctcggtggtgccgatgatgctgcacggcgacgccgcgttcgccggtcagggc
gtggtggccgagacgctcaacatggcactgctgcccggctaccgggtcggcggcaccatc
cacatcgtcgtcaacaaccagatcggtttcaccacagcgccggactactcgcgttccagc
gaatactgcaccgacgtggccaagatgatcggcgcgccgatcttccacgtcaacggcgat
gacccggaagcctgcgactgggtggcccggctggcagtggacttccggcagaagttccac
aaggacgtcatcatcgacatgctgtgctaccgccgccgcgggcacaacgagggcgacgac
ccgtcgatgacgaacccgtacatgtacgacgtgatcggcaccaagagcggtgtccgcaag
agctacaccgaagacctgatcggccgcggcgacatctcgctgaaggaggccgaggacgcg
ctgcgtgactaccacggccagctggagcgggtgttcaacgagatccgcgaactggagaag
catgccgcgctgcccagcgagtcggtggagtccgagcagcaggtgccgcgcggcctgaac
accgcggtcgacaaggcaatgctggcccgcatcggcgacgcgttcatgacgatccccgag
ggcttcaccgtgcacccgcgggtgctgccggtgctggagcgacgccgcgaaatggcgtac
gagggcaaggtggactgggcgttcggcgagctgttggcgctgggctcgctggtcgccgag
ggcaagctcatccggttgtccgggcaggacacccgccgaggcaccttctcgcagcggcat
tcggtgatcatcgaccaggccaacggcgcggagttcagcccgttgcagctgctggccacc
aatgccgacggcaccccgaccggcggcaagttcctggtctatgactcgccgctgtcggag
ttcgccgccgtcggcttcgagtacggctacaccgtcggcaacccggacgccctggtgctg
tgggaggcgcagttcggcgacttcgtcaacggcgcccagtcgatcatcgacgagttcatc
agttccggcgaggccaagtggggtcagctgtccaacgtggtgctgctgctgccgcacggc
cacgagggccagggcccggaccacacctccgggcgcatcgagcgcttcctgcagctgtgg
gcggagggctcgatgacgatcgcggtgccctcgaccccgtcgaactacttccacctgctg
cgccgccacgccctcgacgggatccagcggccgctgatcgtgttcaccccgaagtcgatg
ctgcgcaacaaggcggcgatcagcgacatcaaggacttcaccgacgtcaagttccgctcg
gtgctcgaggaacccacctacgaggacggcgtgggcgaccgcagcaaggtcacccgggtg
ctgctgaccagcggcaagctctactacgagctggtcgcgcgtaaggccaaggacggccgt
gacgacatcgcgatcgtgcggatcgaacagctggccccgctgcccaagcgccgcctcggt
gacaccctggaccgctacccgaacgcgcagcagttcttctgggtgcaggaggagccggcc
aaccagggggcatggccgcggttcggcctggagctgccggagctgctgccggagaagctg
accgggatcaagcggatctcgcgccgcgccatgtcggcgccgtcgtcggggtcgtcgaag
gtgcacgcggtcgagcagcaggagatcatcgactcggccttcagctga
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