KEGG   Methylocystis heyeri: H2LOC_006055
Entry
H2LOC_006055      CDS       T06290                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mhey  Methylocystis heyeri
Pathway
mhey03030  DNA replication
mhey03410  Base excision repair
mhey03420  Nucleotide excision repair
mhey03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mhey00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    H2LOC_006055 (ligA)
   03410 Base excision repair
    H2LOC_006055 (ligA)
   03420 Nucleotide excision repair
    H2LOC_006055 (ligA)
   03430 Mismatch repair
    H2LOC_006055 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mhey03032]
    H2LOC_006055 (ligA)
   03400 DNA repair and recombination proteins [BR:mhey03400]
    H2LOC_006055 (ligA)
Enzymes [BR:mhey01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     H2LOC_006055 (ligA)
DNA replication proteins [BR:mhey03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     H2LOC_006055 (ligA)
DNA repair and recombination proteins [BR:mhey03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     H2LOC_006055 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     H2LOC_006055 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     H2LOC_006055 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      H2LOC_006055 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT PTCB-BRCT DNA_ligase_ZBD Nlig-Ia HALZ Zn_Ribbon_TF Zn_ribbon_TFIIB
Other DBs
NCBI-ProteinID: QGM45291
UniProt: A0A6B8KE59
LinkDB
Position
complement(1350800..1352917)
AA seq 705 aa
MPPRSPKSSQPIEGLTPDEARAEHLRLAAEIAEHDRHYYQEDAPAVSDAEYDALRRRYDA
LEAAFPELATPESLSRKIGAAPAEKFAKVKHVVPMLSLGNVFSDEEVREFVARVRRFLGL
SEDAPLAFTAEPKIDGLSCSLRYEHGRLVSAATRGDGFEGEDVTANIRTIDQIPAELRGG
FGPVLDVRGEVYMTHRDFAALNERQAAAQKQKFANPRNAAAGSLRQLDPAVTAGRPLRFF
AYAWGEASELPAKTQKGVIEAFSHLGFPVNPLTRICANVEEMLEHYRAIEAQRATLGYDI
DGVVYKVDDIALQARLGFVSRAPRWAVAHKFPAEQATTILRGIEINVGRTGALTPVARLE
PVTVGGVVVSNATLHNEDEIERKDVRVGDTVVVQRAGDVIPQIVEVRLDKRPPDAKPYEF
PHVCPVCGSAALREIDEKTGEADVVRRCTGSLVCAAQAVERLKHFASRNAMDIEGLGDKQ
IEYFYQEGLIKTASDIFTLQARDEAGLSRLKNREGFGETSVRNLFAAIDARRRVPINKFI
YALGVRHVGETNAKRLARHFPDFQQLRAAASAAEPGGEAFAAFDEIDGLGPVVAEALHDF
FAEPHNEREIDALLEHVTLEPMPAVESSSPVAGKTVVFTGSLERLTRDEAKAQAERFGAK
ISGSVSKKTDLVVAGPGAGSKLTKAKELGVEVISEDEWFALTGQG
NT seq 2118 nt   +upstreamnt  +downstreamnt
atgccgccgcgctccccgaaatcgtcgcaaccgatagagggcctcacgcccgatgaagcg
cgcgcagagcacctgaggctcgccgcggaaatagccgagcacgaccgccactattatcaa
gaggacgcgcccgccgtttcggacgcggaatatgacgcgttgcggcgacgctacgacgcg
ctcgaagcggcctttcccgagcttgcaactcccgagtcgctgtcccggaagatcggcgcc
gcgccggcggaaaaattcgccaaggtcaagcatgtcgtgcccatgctttcgcttggcaac
gtcttctcagacgaggaggtgcgggagttcgtcgcccgcgtccgtcgtttcctcggtctc
tccgaggacgcgccgctcgcttttacggcggagcccaagatcgacggcctttcctgctcg
ctgcgatacgaacacggccgcctcgtcagcgcggccacgcgcggcgatggtttcgagggc
gaagacgtcaccgccaatattcgcacgatcgaccagattccggccgagctgcgcggcggt
tttggtcccgtgctggacgtgcgcggcgaagtttatatgactcatcgcgatttcgccgcg
ctcaatgaaagacaggccgcggcgcagaaacagaaattcgccaatccccgcaacgccgcc
gccggctccctgcgccagctcgatccggccgtgacggcgggccggccgctgcgctttttc
gcctatgcctggggcgaggccagcgagctgccggccaagacccagaaaggcgtcatcgag
gcgttttcgcacctcggctttccggtcaatcccttgacccggatctgcgccaatgtcgaa
gaaatgctggagcattaccgcgccatcgaggcgcagcgcgcgacgctcggctacgacatc
gacggcgtggtctataaggtcgacgacatcgcccttcaggcgcgtctgggtttcgtctcg
cgcgcgccgcgctgggcggtggcgcataaattcccggccgaacaggcgacgacgatcctg
cgcggcatagagatcaatgtcggccgcaccggcgccctcacgccagtggcgcggctcgag
cccgtcaccgtcggcggcgtggtggtctccaacgccactttgcataatgaggacgagatc
gagcgcaaggacgtgcgcgtcggcgatacggttgtcgtgcagcgcgccggcgacgtcatt
ccccagatcgtcgaggtccggctggacaaacggccgcctgatgcgaagccatatgaattt
ccgcatgtttgcccggtatgcggctcggcggccctgcgggaaatcgacgaaaaaaccggc
gaggccgatgtcgtcaggcgctgcacgggttcgctggtctgcgcggcgcaggcggtggag
cggctcaaacatttcgcctcgcgcaacgccatggacatagaaggcctcggcgacaagcag
atcgagtatttttaccaggaaggcctgatcaagaccgcctcggatatttttacgcttcaa
gcgcgcgacgaagccgggctgtcgcggcttaaaaaccgcgagggcttcggagaaacttcg
gtcaggaatcttttcgcggctatcgacgcgcgcaggcgcgtgccgatcaacaagttcatc
tatgcgctcggcgtcaggcatgtcggcgaaaccaacgccaagcggctggcgcggcatttt
cccgactttcagcagcttcgcgccgcagcgagcgcggccgaacccggcggcgaggctttc
gccgccttcgacgagatcgacgggctcggtcccgtcgtggccgaggcgctgcatgacttt
ttcgccgaaccgcacaatgagcgggaaatcgacgcgctgctcgaacatgtgacgctggag
ccgatgccggcggtcgaatcctcttctccggtcgcgggcaagacggtggtcttcaccggg
tcgctggagcggctcacccgtgatgaggccaaggctcaggccgagcgtttcggcgccaaa
atatcggggtcggtttcgaagaagaccgatctcgtcgtggcgggaccgggcgcgggctca
aagctcaccaaagccaaagagctgggcgtcgaggtgatatccgaagacgagtggttcgcc
ctgaccgggcaggggtga

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