KEGG   MODULE: mhi_M00836
Entry
mhi_M00836        Pathway   Module                                 
Name
Coenzyme F430 biosynthesis, sirohydrochlorin => coenzyme F430
Definition
K22011 K22012 (K21610+K21611) K21612
Diagram
mhi_M00836  Coenzyme F430 biosynthesis, sirohydrochlorin => coenzyme F430
mhi_M00836

Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
mhi00860  Porphyrin metabolism
mhi01240  Biosynthesis of cofactors
mhi01100  Metabolic pathways
mhi01120  Microbial metabolism in diverse environments
Organism
Methanothrix harundinacea [GN:mhi]
Gene
Mhar_0046  Cobyrinic Acid a,c-diamide synthase [KO:K22012]
Mhar_0047  Nitrogenase iron protein 1 [KO:K21610]
Mhar_2389  Sirohydrochlorin cobaltochelatase [KO:K22011]
Mhar_2390  Mur ligase, middle domain protein [KO:K21612]
Mhar_2391  Putative methanogenesis marker 13 metalloprotein [KO:K21611]
Reaction
R11626  
R11627  
R11628  
R11629  
Compound
C05778  Sirohydrochlorin
C21510  Nickel-sirohydrochlorin
C21511  Nickel-sirohydrochlorin a,c-diamide
C21512  15,17(3)-Seco-F430-17(3)-acid
C05777  Coenzyme F430
Reference
PMID:27846569
  Authors
Zheng K, Ngo PD, Owens VL, Yang XP, Mansoorabadi SO
  Title
The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea.
  Journal
Science 354:339-342 (2016)
DOI:10.1126/science.aag2947
Reference
PMID:28225763
  Authors
Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C, Chivers PT, Howard MJ, Rigby SE, Layer G, Warren MJ
  Title
Elucidation of the biosynthesis of the methane catalyst coenzyme F430.
  Journal
Nature 543:78-82 (2017)
DOI:10.1038/nature21427
KO module
M00836
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