Mycolicibacterium holsaticum: K3U96_10670
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Entry
K3U96_10670 CDS
T07607
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mhol
Mycolicibacterium holsaticum
Pathway
mhol00010
Glycolysis / Gluconeogenesis
mhol00020
Citrate cycle (TCA cycle)
mhol00620
Pyruvate metabolism
mhol00785
Lipoic acid metabolism
mhol01100
Metabolic pathways
mhol01110
Biosynthesis of secondary metabolites
mhol01120
Microbial metabolism in diverse environments
mhol01200
Carbon metabolism
mhol01210
2-Oxocarboxylic acid metabolism
Module
mhol_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mhol00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K3U96_10670 (aceE)
00020 Citrate cycle (TCA cycle)
K3U96_10670 (aceE)
00620 Pyruvate metabolism
K3U96_10670 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
K3U96_10670 (aceE)
Enzymes [BR:
mhol01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
K3U96_10670 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QZA14520
LinkDB
All DBs
Position
complement(2222472..2225261)
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AA seq
929 aa
AA seq
DB search
MTTEFARQDLAQNSSTPAEPDRVRVIREGVASYLPDIDPEETGEWLESFDQLVERSGPAR
ARYLMLRLLERSREKRVAIPALTSTDYVNTIPTESEPWFPGDEEVERRFRTWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKAHPGGGDQVFVQGHASPGIYARAF
LEGRLTADDLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHY
LHNRGIKDTSDQHVWAFLGDGEMDEPESRGLAHVAALEGLDNLTFVVNCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLQADKDGALVNLMNVTPDGDYQTYKANDG
GYVREHFFNRDPRTKQLVQHLSDQEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALEDLKYFRDAMRVPVSDAQLDEDPYLPPYYHPGPEAP
EIRYLLERRRALGGWVPERRNKGKVLALPGRDTYKSLKKGSGNQEVATTMATVRTFKELL
RDKEIGWRIVPIIPDEARTFGMDSWFPNLKIYNPNGQLYTSVDAELMLAYKESEVGQILH
EGINEAGSSGSFIAVGTSYSTHNEPMIPVYIFYSMFGFQRTGDNLWAAGDQMTRGFLLGA
TAGRTTLVGEGLQHADGHSPLLASTNPAVVAYDPAFAYEIAYIIESGLDRMYGEKQENVF
FYITIYNEPYKQPAEPENLDVEGLLHGIYRYRPAPQQRANVAQILASGVAMPEALRAAEL
LATDWDVAADVWSVTSWGELNRDGVAIEKQRLRHPDRPAETAYVTKALADAAGPVVAVSD
WMRAVPEQIRPWVPGTYITLGTDGFGFSDTRPAARRFYNTDAESIAVAVLEGLARDGNID
QSVAVDAANRYQIDDVLAAPEQTSDPGVA
NT seq
2790 nt
NT seq
+upstream
nt +downstream
nt
ttgaccaccgagttcgcgcgccaggacctggcccaaaactccagcaccccagcagaaccc
gatcgggttcgagtgatccgcgaaggggtcgcgtcttacctgcccgatatcgatcccgaa
gagaccggcgaatggctcgagtcgttcgatcagctggtggaacgctcggggcccgcgcgg
gcccgctacctgatgctgcgcctgctggagcgctcccgcgagaagcgcgttgccattccg
gcgctgacgtccactgactacgtcaacacgatccccaccgaatccgagccctggttcccc
ggtgacgaggaagtcgaacgccgcttccggacctggatccggtggaacgccgcgatcatg
gtgcaccgcgcgcaacgtccgggagtcggtgtcggaggccatatttcgacgtatgcgtcc
tccgcggcgctgtacgaggtgggcttcaaccacttcttccgcggcaaggcccaccccggc
ggcggggaccaggtgttcgtccaggggcacgcctcgccggggatctacgcccgggcgttc
ctggagggccggctgaccgccgacgacctcgacgggttccgccaggaacacagccatccc
ggcggcgggctgccgtcctatccgcacccgcggctgatgccggacttctgggagttcccc
acggtgtcgatggggttgggcccgatgaacgccatctaccaggcccggttcaaccattac
ctgcacaaccgcggcatcaaggacacctccgaccagcacgtgtgggcgtttctgggcgac
ggcgagatggacgagcccgaaagccgcgggctggcccacgtggcggcgttggagggtttg
gacaatctgaccttcgtcgtcaactgcaacctgcagcgcctggacggcccggtgcgcggc
aacggcaagatcatccaggaactggagtcgttcttccgcggcgcgggctggaacgtcatc
aaggtggtgtggggccgcgagtgggatgcgctgctgcaggccgacaaggacggcgccctg
gtgaacctgatgaacgtcacccccgacggcgactaccagacctacaaggccaacgacggc
ggctacgtccgtgagcacttcttcaaccgcgacccgcgcaccaagcaactggtgcagcac
ctgtccgatcaggagatctggaacctcaagcgcggtgggcacgactaccgcaaggtgtat
gccgcctaccgcgccgcgatggagcacaagggccagccgacggtcatattggccaagacc
atcaagggctattcgctgggcgcccacttccagggccgcaacgccacccatcagatgaaa
aagcttgcgctggaagacctcaagtacttccgcgacgcgatgcgggttccggtcagcgac
gcccaactcgacgaggacccgtacctgccgccgtactaccacccgggtccggaggccccc
gagatccggtatctgctcgaacgccgccgggcgctgggcggctgggtgccggagcgacgc
aacaagggcaaggtgctggctctgcccgggcgcgacacctacaagtcgctcaagaagggg
tcgggcaaccaagaggtggccaccaccatggccaccgtgcgcacgttcaaagaactgttg
cgcgacaaggagatcggctggcgcatcgttccgatcattcccgacgaggcccgcacgttc
gggatggactcgtggttcccgaacctcaagatctacaaccccaacgggcagctgtacacc
tcggtggacgccgagttgatgttggcctacaaggaaagcgaagtgggccagatcctgcac
gagggcatcaacgaagccggctcgtcgggcagcttcatcgccgtcggcacgtcgtactcg
acgcacaacgagccgatgatcccggtctacatcttctattcgatgttcgggttccagcgc
accggcgacaacctgtgggccgccggtgaccagatgacgcgcggtttcttgctgggcgcg
acggccgggcgcaccaccctggtcggcgagggcctgcagcacgccgacgggcactcgccg
ctgctggcctcgaccaacccggcggtggtggcctacgacccggcgttcgcctacgagatc
gcctacatcatcgaaagcggcctggaccgcatgtacggcgagaagcaggagaacgtcttc
ttctacatcaccatctacaacgagccctacaagcagcccgccgagccggagaacctcgac
gtcgagggcctgctgcacggcatctaccggtaccggcccgcgccgcagcagcgggccaac
gtcgcgcagatcctggcctcgggggtggccatgcccgaggccctgcgcgcggccgagctg
ctggccaccgactgggacgtcgccgccgacgtctggtcggtcaccagctggggcgagctc
aaccgcgacggcgtggcgatcgagaagcaacggctgcgccatcctgaccgtccggccgag
accgcctacgtcacaaaggcgctcgccgatgcggccgggccggtggtcgcggtcagcgac
tggatgcgcgcggtgcccgaacagatccggccctgggtgccgggcacctacatcacgctg
ggcaccgacggcttcggcttctccgacacccgccccgccgcgcgccgcttctacaacacc
gacgccgagtcgatcgccgtcgcggtgctcgaggggctggcccgcgacggcaacatcgac
cagtcggtcgccgtcgacgccgcgaaccggtaccagatcgacgatgtcctggccgcaccc
gagcagacgtcggaccccggagtggcgtag
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