Microcella humidisoli: NNL39_00935
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Entry
NNL39_00935 CDS
T09551
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mhum
Microcella humidisoli
Pathway
mhum00020
Citrate cycle (TCA cycle)
mhum00630
Glyoxylate and dicarboxylate metabolism
mhum00785
Lipoic acid metabolism
mhum01100
Metabolic pathways
mhum01110
Biosynthesis of secondary metabolites
mhum01120
Microbial metabolism in diverse environments
mhum01200
Carbon metabolism
mhum01210
2-Oxocarboxylic acid metabolism
Module
mhum_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mhum_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mhum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
NNL39_00935
00630 Glyoxylate and dicarboxylate metabolism
NNL39_00935
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NNL39_00935
Enzymes [BR:
mhum01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
NNL39_00935
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
NNL39_00935
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
NNL39_00935
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
NNL39_00935
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
SHOCT
Motif
Other DBs
NCBI-ProteinID:
UTT62718
UniProt:
A0ABY5FXB6
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All DBs
Position
211134..214907
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AA seq
1257 aa
AA seq
DB search
MSSQVTGVGPDGNAAGEFGANEWLVDELYEQYKVDKNTVDPSWWPILEKYHQSSTAGAVD
APPPSTIPIDAPPPAESSAAAVPSAAVPSASSASVPSAAVPATGSQPVARTTSIAPQPTP
IPAQAPAPTTGAMTLPVDADGDGELDDIVTPLKGMAKTLATNMDASLSVPTATSVRTIPA
KLMIDNRIVINNHLKRARGGKVSFTHLIAWAMVRALREFPSQNVYYDEVDGKPVVVTPAH
INLGIAIDLPKPDGTRSLLVPGIKRCEGMGFGDFIAAYEDVVKRARDNKLTATDFQGNTI
SLTNPGGIGTVHSVPRLMKGQGAIIGAGALEYPAEFQGMSQATLADLGIGKTITLTSTYD
HRVIQGAGSGEFLKKVHELLIGERRFYEDIFADLRIPYDPIHWAQDIHVDLADQINKTAR
VHELINAYRVRGHLMADVDPLEYRQRSHPDLDISSHGLTFWDLDREFVTAGFGGRRTMLL
REVLGVLRDTYCRTVGIEYMHIQEPEQRRWFQERLEKPYQKPTHDEQMRILGKLNQAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDELLQGAAEQGLDEVAIGMAHRGRLNVLANIAGK
TYGQIFREFEGTQDPKSVQGSGDVKYHLGTEGVFTSAAGQEVGVYLAANPSHLEAVNGVL
EGIVRAKQDRKNDGAFSTLAVLVHGDAAMAGQGVVVETLQLSMLRGYRTGGTIHVVVNNQ
VGFTTPPGEGRTSIYSTDVAKTIQAPIFHVNGDDPEAVVRVAELAFAYRQQFKRDVVIDL
VCYRRRGHNEGDDPSMTQPLMYNLIEAKRSVRTLYTEALVGRGDITEEEFEAAHRDFQDR
LEVAFAETHAAQTGSMPVITGTPAPETDDLAGEPESTGVDQAVIQHIGDAHDNPPAGFTV
HTKLQAMLKKRVEMSRTGQIDWGFGELLALGSLLMEGTPVRMAGQDSRRGTFVQRHAVLH
DRVNGQEWLPLANLSESQAKFWIYDSLLSEYAAMGFEYGYSVERPDALVLWEAQFGDFAN
GAQTIIDEFISSAEQKWNQRSSVVLLLPHGYEGQGPDHSSARIERFLQLAAEENMTIARP
STPASYFHLLRRQAYARPRRPLIVFTPKAMLRLRGATSEVADFTSGRFEPVIDDATIVDA
GAVRRVLLHAGKIHYDLKAEVEKRGTTGVALVRLEQYHPLPEAQLRAVLDRYPNAEVVWV
QDEPENQGAWPFLALEGQKRGMRPMRVVSRHASASPATGSSKRSAQEHADIMDAALS
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
gtgtcaagccaagtgaccggagtcggccctgacggcaacgccgcgggcgaattcggagcc
aacgagtggctcgttgacgaactctacgagcagtacaaggtcgacaagaacacggtcgat
ccctcctggtggccgattctcgagaagtaccaccagtcgtcgaccgcgggtgcggtcgac
gcgccgccgccctcgacgatccccatcgacgcgccgccgcccgcggagtcctccgccgca
gccgtgccgagcgccgcagtgccgtccgcctcgtcggcgtcggtcccctccgccgccgtg
cccgccaccggcagccagcccgtcgcacgcaccacctcgatcgccccgcagcccacgcct
attccggcccaggcgcccgcgccgacgaccggcgccatgacgctgcccgtcgacgccgac
ggcgacggcgagctcgacgacatcgtcacgcccctcaagggcatggccaagaccctcgcg
accaatatggatgcgagcctctcggtgcccaccgcgacgagcgtgcgcaccatccccgcg
aagctgatgatcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcgcgcggcggc
aaggtcagcttcacgcacctcatcgcctgggcgatggtgcgcgcgctgcgcgagttcccc
agccagaacgtctactacgacgaggtcgacggcaagcccgtcgtcgtcacccccgcccac
atcaacctgggcatcgcgatcgacctgcccaagcccgacggcacgcgctcgctgctggtt
cccggcatcaagcgctgcgagggcatgggcttcggcgacttcatcgccgcctatgaagac
gtcgtcaagcgcgcccgcgacaacaagctcacggccaccgacttccagggcaacacgatc
tcgctgacgaacccgggcggcatcggcaccgtgcactcggtgccgcggctcatgaagggc
cagggcgccatcatcggcgccggtgcgctcgagtacccggccgagttccagggcatgtcg
caggcgaccctcgccgacctcggcatcggcaagaccatcacgctcacgagcacctatgac
caccgcgtcatccagggcgccggctcgggcgagttcctcaagaaggtgcacgagctgctc
atcggcgagcgccgcttctacgaagacatcttcgccgacctgcgcattccctacgacccg
atccactgggcgcaagacatccacgtcgatctggccgaccagatcaacaagaccgcgcgc
gtgcacgagctcatcaacgcctaccgcgtgcgtggccacctcatggccgacgtcgacccg
ctcgagtaccgccagcgcagccaccccgacctcgacatctcgagccacggcctgaccttc
tgggatctcgaccgcgagttcgtcacggcgggcttcggcggccggcgcacgatgctgctg
cgcgaggtgctcggcgtgctgcgtgacacctactgccgcacggtcggcatcgagtacatg
cacattcaggagccggagcagcgccgctggttccaggagcgcctcgagaagccgtaccag
aagccgacgcacgacgagcagatgcgcatcctcggcaagctcaaccaggccgaggcgttc
gagaccttcctgcagaccaagtacgtcggtcagaagcgcttcagcctcgagggcggcgag
agcgtcatcccgctgctcgatgagctgctgcagggcgccgccgagcaggggctcgacgag
gtcgccatcggcatggcgcaccgcgggcgcctcaacgtgctcgccaacatcgccggaaag
acctacggccagatcttccgcgagttcgagggcacgcaagaccccaagtcggtgcagggc
tcgggcgacgtcaagtaccacctcggcaccgagggcgttttcacgtcggccgcgggccaa
gaggtcggcgtgtatctcgccgcgaacccctcgcacctcgaagccgtcaacggcgtgctc
gagggcatcgtgcgggcgaagcaggaccgcaagaacgacggcgcgttcagcaccctcgcg
gtgctcgtgcacggcgacgccgcgatggccggtcagggcgtcgtggtcgagacgctgcaa
ctcagcatgctgcgcggctaccgcacgggcggcaccatccacgtggtcgtcaacaaccag
gtgggcttcacgacgcctcccggcgagggccgcacgtcgatctactcgaccgatgtcgcc
aagaccatccaggcgccgatcttccacgtcaacggcgacgaccccgaggccgtcgtgcgc
gtggccgagctggctttcgcctaccgtcagcagttcaagcgcgatgtcgtcatcgacctg
gtctgctaccgccgccgcggccacaacgagggcgacgacccctcgatgacgcagccgctc
atgtacaacctcatcgaggccaagcgctcggtgcgcacgctctataccgaggcgctcgtc
ggccgcggcgacatcaccgaggaggagttcgaggccgcgcaccgcgacttccaagaccgc
ctcgaagtcgctttcgccgagacgcacgccgcccagacgggctccatgcccgtcatcacg
ggcacgccggctcccgagaccgacgacctcgccggcgagcccgagtcgacgggcgtcgat
caggcggtcatccagcacatcggcgacgcgcacgacaacccgcccgccgggttcaccgtg
cacaccaagctgcaggcgatgctcaagaagcgcgtcgagatgagccgcaccggccagatc
gactggggcttcggcgaactgctcgctctcggctcgctgctcatggagggcacgcccgtg
cgcatggccgggcaggactctcgtcgcggcaccttcgtgcagcgccacgccgtgctgcac
gatcgcgtcaacggccaggaatggctgccgctcgccaacctcagcgagagccaggcaaag
ttctggatctacgactcgctgctgagcgagtacgcggccatgggcttcgagtacggctac
tcggtcgagcgccccgacgcgctcgtgctgtgggaggcccagttcggcgacttcgccaac
ggcgcccagacgatcatcgacgagttcatctcgtcggccgagcagaagtggaaccagcgc
tcgagcgtcgtgctgctgctgccgcacggctacgagggccaggggcccgaccactcctcg
gcgcgcatcgagcggttcctgcagctcgcggccgaagagaacatgacgatcgcgcggccc
tcgacgcccgcctcgtacttccacctgctgcgccgtcaggcctacgcgcgcccgcgccgc
ccgctcatcgtcttcaccccgaaggccatgctgcggctgcggggtgcgacgagcgaggtc
gccgacttcacgagcggtcgcttcgagcccgtcatcgacgacgcgacgatcgtggatgcc
ggcgccgtgcgccgggtgctgctgcacgccggcaagatccactacgacctcaaggccgag
gtcgagaagcggggaacgaccggagtcgccctcgtgcgcctcgagcagtaccacccgctg
ccggaggcccagctgcgcgccgtactcgaccgctaccccaacgccgaggtcgtgtgggtg
caggacgagcccgagaaccagggcgcctggccgttcctcgcgctcgagggtcagaagcgc
ggcatgcggccgatgcgcgtggtctcgcggcacgcgtcggcctcgccggcgacgggctcg
agcaagcgcagcgcgcaggagcacgccgacatcatggatgcggcgctgagctga
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