Mannheimia haemolytica M42548: MHH_c12100
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Entry
MHH_c12100 CDS
T02635
Symbol
metH1
Name
(GenBank) cobalamin-dependent methionine synthase MetH
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mhx
Mannheimia haemolytica M42548
Pathway
mhx00270
Cysteine and methionine metabolism
mhx00450
Selenocompound metabolism
mhx00670
One carbon pool by folate
mhx01100
Metabolic pathways
mhx01110
Biosynthesis of secondary metabolites
mhx01230
Biosynthesis of amino acids
mhx04981
Folate transport and metabolism
Module
mhx_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mhx00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MHH_c12100 (metH1)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
MHH_c12100 (metH1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
MHH_c12100 (metH1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
MHH_c12100 (metH1)
04980 Cobalamin transport and metabolism
MHH_c12100 (metH1)
Enzymes [BR:
mhx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
MHH_c12100 (metH1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
AGK01663
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All DBs
Position
1146564..1150280
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AA seq
1238 aa
AA seq
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MNTQHRTELLQNALTERILILDGAMGTMIQKYKLTESDFRGERFKNSTIDLKGNNDLLTL
TQPLLISAIHEKYLAAGADIIETNTFSATTIAQADYELESIAYELNLVGAKLARLAADKF
SIPEKPRFVAGILGPTNRTCSISPDVNDPGFRNITFMQLVEAYAEATRGLIEGGADLIMI
ETIFDTLNAKAAVFAIETVFDELGVKLPIMISGTITDASGRTLSGQTTEAFYNSLRHAKP
LTFGLNCALGPKELRPYVEMMSKISETFVSVHPNAGLPNAFGGYDLGAEEMATYIKEWAE
LGWLNIVGGCCGTTPEHIQAFAEATKGVAPRKLPEIPTAMRLSGLEPLTIDDNSLFVNVG
ERNNVTGSAKFKKLIKEEKFAEAIEIAISQVENGAQVIDVNMDEALLDSKKCMTRFLNIL
ATEPEAAKVPIMIDSSKWEVIEAGLQTVQGKPIVNSISLKEGEEKFIHQAKLCRRYGAAV
VVMAFDEVGQADTEERKVEICTRAYRILVDQLGFPPEDIIFDPNIFAIATGIEEHNNYGV
DFIQACERIKRDLPHAKISGGVSNVSFSFRGNNVVREAIHAVFLYYAIKAGMDMGIVNAG
QLAIYDDLDPELREAIEDAVLNHRHDTTDRLLEISEKYRGVKVESADESAAEWRNLPVAE
RLKHALVKGITTYIIEDTEEARQQFASPLEVIEGPLMAGMDVVGDLFGDGKMFLPQVVKS
ARVMKQSVAYLEPYINATKQKGSSNGKMVIATVKGDVHDIGKNIVSVVLQCNNFEVIDLG
VMVPADVIIETAIREKADLIGLSGLITPSLDEMEYFLGEMNRLKLDIPVLIGGATTSKEH
TAIKLYPKYNYPVVYTANASRCVTVCATLMNPEAKAEFWEKTKAEYEEIQRKFAVRKPLR
NGLSIEEARANRFDGFSGEWADYVPPTPKQTGIIEYKNVPIATLRKFIDWSPFFMLWGLM
GGYPDAFDYPEGGEEARRVYNDAQRVLDEFEQNGKLNPSGIMGIFPAVREGDDIAILNED
RTACIGKSYHLRQQSERGKNSKSPYNLCLSDFIADRESGQQDWFGMFAVCAGIEEHYLVE
SYKAAGDDYNAILLQAVGDRLAEAMAEYLHFELRTKVWGYTVEDEDNGRLIREEYIGIRP
APGYPSCPEHTEKQIIWDLLEVEQRIGMKLTESYAMWPAASVCGWYFTHPTSNYFTLGKI
DEDQVLDYAKRKGWDELTAKKWLSVAMKQDVKSQAENI
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atgaacacgcagcatagaaccgaattacttcaaaatgcccttaccgaacgcattcttatc
ttagacggtgcgatgggaacgatgatccaaaaatataaactaaccgaatctgatttccga
ggtgaacgttttaaaaacagtaccatcgatcttaaaggcaataacgacctactcacactc
acccagccactcctgatttctgctattcacgagaaatatttagccgccggtgcggatatt
atcgaaactaatacctttagtgcgacgaccattgctcaagcagattatgaacttgaaagt
attgcttatgagctgaatcttgtgggggcaaaacttgcccgtcttgccgccgataaattc
tccatccctgaaaaacctcgttttgttgccggtattcttgggccgactaaccgtacttgt
tcgatttcccctgatgttaatgaccccggtttccgtaacattacctttatgcaactggtg
gaagcctatgccgaggcaacccgtggtttgattgaaggtggggcggatctgattatgatc
gaaaccattttcgataccctgaatgccaaagcggcggtgtttgcaattgaaacggtgttt
gatgaactgggcgtgaaattgccgataatgatctccggcaccattaccgatgcctcaggg
cgaacgctgtcagggcagaccacggaggcgttttataactcgctccgccacgccaaaccg
ctgacgttcggcttgaactgtgcgctcgggccgaaggaactccgcccttatgtagagatg
atgtcgaaaatcagtgagacttttgtttcggttcacccgaatgccggcttgccaaacgct
tttggcgggtacgatttaggggcggaagagatggcgacttacatcaaagagtgggcagaa
ctcggctggctgaatattgtcggcggctgttgtggcaccacgccggagcatatccaagcc
tttgccgaagcaaccaaaggcgttgcgcctcgtaaattacctgaaattccaaccgctatg
cgtttgtcgggcttagaaccgctgacgattgacgataattcgctgtttgtgaatgtgggc
gaacgcaataacgtcaccggttcggcaaaatttaagaagctgattaaagaagaaaaattt
gcggaagcgattgaaattgccatcagccaagtggaaaacggggcgcaggtgattgacgtg
aatatggacgaggcgttgctcgattccaaaaaatgtatgacccgtttcctcaacattctt
gctaccgaacctgaggcggcaaaagtgccgattatgattgactcctcgaaatgggaggtg
atcgaggcgggcttgcaaacggtgcagggcaagccgatagtgaactccatttcactcaaa
gagggcgaagagaaatttattcaccaagccaaactctgccgccgctatggggctgcggtg
gtggtgatggcatttgacgaagtcgggcaagcggataccgaagaacgcaaggtagaaatt
tgtacccgagcttatcggattttggttgatcagctcggcttcccaccggaagacattatt
ttcgacccgaacatttttgcgattgccaccggtattgaagaacacaataactacggcgtg
gattttatccaagcctgtgagcggattaaacgagacttgccacacgccaaaatttccggc
ggggtgtcgaatgtctctttctctttccgaggcaacaatgtggtgcgtgaggctattcac
gccgtgttcctctactatgcgatcaaagccggaatggatatggggatcgtgaacgcaggg
cagttggcgatttatgacgacctcgaccctgaactgcgagaggcgattgaagatgcggtg
ctgaaccaccgtcatgacactaccgaccgcctgttggaaatttccgaaaaatatcggggc
gtaaaagtagaaagtgccgatgaaagtgccgccgagtggcgaaatttacctgtggcagag
cgtttaaaacacgccctcgtaaaaggcataacgacctacattattgaagataccgaagag
gctcgccagcaatttgcctctccgctggaagtgattgaagggccgctcatggcgggtatg
gacgtggtgggcgacctgttcggagacggcaaaatgttcctgccgcaagtggtgaaatcg
gctcgggtaatgaaacagtccgttgcctatttagagccgtacatcaacgccaccaagcag
aaaggatcgagcaacggcaaaatggtgatcgccaccgtgaaaggtgatgtacacgacatc
ggcaaaaacatcgttagcgtggtgttgcagtgcaataactttgaagtgatagacttaggc
gtgatggtgcctgccgatgtaattatcgaaactgctattcgggagaaagccgatctcatt
gggttaagcggactaattaccccatcgctggacgaaatggagtattttttaggtgaaatg
aaccgcttgaagctcgatattccggtgctgattggcggcgcaacgacctcaaaagagcat
acggcgatcaaactttatccgaaatataactaccccgtagtctataccgccaacgcttca
cgttgcgtaaccgtctgtgcgaccttgatgaaccctgaggcaaaagccgaattttgggaa
aaaaccaaagccgaatacgaagaaattcagcgtaaatttgccgttcgcaaaccacttcgc
aacggtttatctattgaggaggctcgagccaatcgttttgacggatttagtggcgaatgg
gcagactatgtgccgccaacgccaaaacagaccggcattatcgagtacaaaaatgtaccg
attgccaccctacgcaaatttatcgactggtcgccgttctttatgctctggggcttaatg
ggcggttatcctgatgcctttgattatccggaaggcggcgaagaggcacgccgtgtctat
aacgatgcccaacgggtgctggacgaatttgagcaaaacggcaagctcaacccaagtggg
attatgggcattttccctgccgtgcgtgagggcgatgatattgcaattttaaacgaagat
cgcaccgcttgtatcggcaaatcctaccacctccgccaacaatccgaacgaggcaaaaac
agcaaaagcccgtacaacctctgtttaagcgattttatcgccgaccgagaaagcggacaa
caagactggttcggaatgttcgccgtttgtgccggcattgaagaacactatttagttgaa
agctacaaagcggcaggcgatgactacaacgccattttgctccaagccgttggcgaccgc
ttggcagaagcaatggcggaatacctacactttgagctacgtaccaaagtctggggctac
accgtggaagacgaagacaacggacgcttaatccgtgaagaatacatcggcatccgccct
gcgcccggctacccaagctgcccggaacacaccgagaaacagataatttgggacttgtta
gaggtggaacaacgcatcggcatgaaactcaccgaaagctatgccatgtggccggcagca
agtgtctgcggctggtacttcacccaccctaccagcaactacttcactctcggcaagatt
gatgaagatcaggtgttggattacgccaaacgcaaaggctgggacgaactcacggcgaag
aaatggttaagtgtggcgatgaaacaagatgtcaagtcgcaggctgaaaacatttaa
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