KEGG   Mannheimia haemolytica M42548: MHH_c19240
Entry
MHH_c19240        CDS       T02635                                 
Symbol
acrB
Name
(GenBank) AcrB RND-type permease
  KO
K18138  multidrug efflux pump
Organism
mhx  Mannheimia haemolytica M42548
Pathway
mhx01501  beta-Lactam resistance
mhx01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:mhx00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    MHH_c19240 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    MHH_c19240 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mhx02000]
    MHH_c19240 (acrB)
   01504 Antimicrobial resistance genes [BR:mhx01504]
    MHH_c19240 (acrB)
Transporters [BR:mhx02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   MHH_c19240 (acrB)
Antimicrobial resistance genes [BR:mhx01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    MHH_c19240 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C Macro
Other DBs
NCBI-ProteinID: AGK02371
LinkDB
Position
1795066..1798233
AA seq 1055 aa
MKFTDIFIKRPVLAVCISLLITILGLQAIEKLQVREYPEMTVSIVTVSVNYSGADARLMQ
TLVTSQLEEAVAQADNIDYMTSSSSPSTTTVTAKMKLNTDPNAALSDISAKVNAVRSNLP
SGIDDPSIRVSTGSNDALMYIRFVSDELNTSQVTDYINRVVKPQFFTVNGVSSVDVYGSV
FGLRIWLDPDKMASNNLSGAAVLSALSANNLQTAAGNSNGYYTVYRNKVLSTTPSVTELE
EVTVSTTKDGKTIKLKDIATVELDKYQDAARATVGGKDAVVLAVSVAATANSLTVAKDIY
PMFEQVLKNLPSTIQGDIVYDKTIAIDSSIKEVIKTIGEATVIVLVVIILFLGSLRAMIV
PVITIPISLIGVLFFLQMFGFSINLLTLLALVLAIGLVVDDAIVVLENVERHVKEGKTPF
DAAIIGTREIALPVISMTITLGAVYSPMALMTGVTGTLFKEFALTLAGAVFISGIAALTL
SPMMSSRILKEHKEGEESAFARVVHRSLDKMTSCYTNMLSGIMAVRGFVLFFAVLIFASL
PMLFGSLSSEVAPTEDRGFVVGISNGPSNTNLDYTEAALAQFNQEVTKLPEVSSLMTVSG
FNGANSALSIIALKDWNDRSRERAAISNDVAAIGKKVVGMDVNAIAFPEISTGENDLPFS
LVITTADSYEKLAIVASEFLKKAQTSGQFFFANLDLKFDTVTMNMKFDREKMGAYGVTMQ
QVSGTLGAFLSGAIITRVDIDSRAYPIVSQAVRNDRLNPEDLMNYYVTTATGQSIPLGSF
VTMELKTSPSSLPRMSQLNSATIGGVVSGSIGDAVNWAKAELDRTLPSGYQYDFRGESRQ
FVQEGNAMAMTFALAVIIIYLVLAIQFESWRDPLVILVSVPLAVSGALLVMNIPTAMKGL
FMGIAAGTGSKDMMAFANGIWTAGYTLNIYSQVGLITLVGLITKHGILMCEVAKEEQLLH
GKSRYEAIFHAATIRLRPIMMTTAAMIAGLIPLLFAVGAGAIARFSMGMVIVAGLAIGTL
FTLFILPVIYTFLGQEHKPLREFDEEKYFPTTKEA
NT seq 3168 nt   +upstreamnt  +downstreamnt
gtgaaatttactgacatctttattaaacgtcctgttttggcagtttgtatcagcctattg
attacgatcctaggcttgcaagcaatcgaaaaattgcaggtgcgtgaatatccggagatg
acggtctcgattgtaaccgtgagtgttaactattcaggtgcagatgcacgtttaatgcag
acactggttacctcacagttagaagaggctgttgctcaagcggataatattgactatatg
acttcatcaagctctccaagtaccactacggtaacggcaaaaatgaagttaaataccgat
ccgaatgccgcactttccgatatttcggcaaaagtgaatgcggtacgctcaaatttaccg
agcggtattgatgatccgtcaattagagtctcaaccggttcaaatgatgcgttaatgtat
atccgatttgtctctgatgaacttaatacatcacaagttaccgattatattaaccgtgta
gtaaaaccacagttctttacggtaaatggtgtttctagcgttgatgtgtatggctctgtt
tttggcttacgcatctggcttgatccggataaaatggcgagcaataacctatcaggggcg
gctgtattatcggcattaagtgccaataacttgcaaaccgctgcgggtaattctaacggt
tactatacggtttatagaaacaaagtactttctaccacgccttctgtgacagagttagaa
gaggttacggtttcaaccaccaaagatggaaaaaccatcaaattaaaagatattgcgact
gttgagctggataaataccaagatgcagcaagagcaacggttggcggtaaagatgcagtt
gtgcttgctgtttcggtagccgcaacggcaaactctttaaccgtagcgaaagatatttat
ccgatgtttgagcaggtattaaaaaatctaccaagcaccattcaaggagatattgtttac
gataaaaccattgcgattgatagttctatcaaagaagtaattaaaactattggtgaggca
accgtcattgtattggtagtaattatcctgttcttaggttcattacgagcaatgattgta
ccggtgattaccattccgatttccttaatcggggtattattcttcctgcaaatgtttggt
ttctcgatcaacttgcttactttgctggcgttggtattagcgatcggcttggtagtggac
gatgcgattgtcgtacttgaaaacgtagaacgtcacgttaaagaaggtaaaacgccattt
gatgcagcgattatcggtacacgtgaaattgctttaccggttatttcaatgactattact
ctgggtgcagtatattcaccaatggcattaatgaccggggtaacagggacactatttaaa
gagttcgctttaacgcttgccggtgcggtatttatttcggggattgcggcattaaccctt
tcgccgatgatgtctagccgaatattaaaagaacataaagaaggggaagagtcagcattt
gcccgcgtggtgcatagatcactagataaaatgaccagctgctataccaatatgctaagc
ggtattatggctgttcgtggtttcgtcttattctttgcggtgctgatcttcgccagttta
ccgatgttatttggctcactttccagtgaagttgcaccgacagaagaccgtggctttgtg
gttggtatttctaatggaccttcaaacaccaatttagattataccgaagcagcgttagcc
caatttaatcaggaagtaactaaattacctgaagtatcttccttaatgacagtttcaggc
tttaatggtgcaaatagtgcattatcgattattgcattaaaagattggaatgatcgtagc
cgtgaacgtgctgcgatttctaatgatgtggctgcaatcggtaaaaaagtggtgggtatg
gacgtgaatgcaattgcattccctgaaatttcaaccggtgaaaatgatctaccattctca
ttagtgattactaccgctgatagctatgaaaaattggcaatcgttgcctctgaattcttg
aaaaaagcccaaacttccggtcagttcttctttgcgaatttagatttgaaatttgatacg
gtcacgatgaatatgaaattcgaccgtgaaaaaatgggtgcttatggcgtgacaatgcag
caggtgagtggcacattaggggcattcttatccggtgcgattattactcgtgtcgatatt
gactctcgtgcttacccgattgtgtcgcaagcggtgcgtaatgatcgtttaaatcctgaa
gatttaatgaattactatgtcacgactgcaacagggcaatctatcccgttaggttcattt
gtgacgatggaattaaaaacatcaccatcttctttacctcgtatgagccaattaaactcg
gccaccattggtggggtagtatctggctcaatcggcgatgcggtaaattgggcgaaagca
gaattagatcgcactttaccatcaggttatcaatatgacttccgtggtgaatctcgccag
ttcgttcaagaaggtaatgcgatggcaatgactttcgctctagcagttatcattatctat
cttgtacttgcaattcaatttgaatcttggcgtgacccattagtaattttggtttctgtg
ccgttagctgtgagtggtgcattgttggtaatgaacattccaaccgcaatgaaaggcttg
tttatggggattgcagcaggcactggctcgaaagatatgatggcattcgccaacggtatt
tggacggcaggttataccttaaatatctattcacaagtaggtctaattacccttgtcggc
ttaattactaaacacggtatcttgatgtgtgaagtggcgaaagaagagcagttactgcac
ggcaaatcacgctatgaagctattttccacgcagccacgattcgtttacgcccaattatg
atgacaacggcagcaatgattgcaggcttaattccgcttctgtttgcggtgggtgccggt
gcaatcgcccgcttcagtatgggtatggtaatcgtagcaggcttggcaatcgggacattg
tttactctgtttatcttgccggttatctacactttcttagggcaagaacacaagccatta
cgtgaatttgacgaggaaaaatatttcccaacgacaaaagaagcatag

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