Mycobacterium intracellulare ATCC 13950: OCU_12900
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Entry
OCU_12900 CDS
T02158
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mia
Mycobacterium intracellulare ATCC 13950
Pathway
mia00020
Citrate cycle (TCA cycle)
mia00630
Glyoxylate and dicarboxylate metabolism
mia00785
Lipoic acid metabolism
mia01100
Metabolic pathways
mia01110
Biosynthesis of secondary metabolites
mia01120
Microbial metabolism in diverse environments
mia01200
Carbon metabolism
mia01210
2-Oxocarboxylic acid metabolism
Module
mia_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mia_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mia00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
OCU_12900
00630 Glyoxylate and dicarboxylate metabolism
OCU_12900
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OCU_12900
Enzymes [BR:
mia01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
OCU_12900
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
OCU_12900
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
OCU_12900
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
OCU_12900
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AFC42509
UniProt:
H8IHT5
LinkDB
All DBs
Position
complement(1298610..1302362)
Genome browser
AA seq
1250 aa
AA seq
DB search
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGEAATATPTSGDGRP
PAAPAKPAAAAPAKPAAAAPESPKPAPPASTAPPVSTAAGNGVPARPAPVKAAAPPPAEG
DELQTLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTH
LLGYALVQAIKKFPNMNRHYAEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKGC
ETMRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIG
VGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDAFW
DEIFRELGNPYLPVRWSTDNPDSIVDKTARVMELIAAYRNRGHLMADIDPLRLDGSRFRS
HPDLEILNHGLTLWDLDRVFKVNGFAGSEYKKLRDVLGLLRDAYCRHIGVEYTHILDPEQ
QEWLQQRVETKHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESIIPMMD
AAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYH
LGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDRRAEDQGDDKAFSV
VPMMLHGDAAFAGQGVVAETLNLTHLPGYRVGGTIHIIANNQIGFTTAPEYSRSSEYCTD
VAKMIGAPIFHVNGDDPEACAWVAKLAVDFRQEFKKDVVIDMLCYRKRGHNEGDDPSMTN
PAMYDVVDIKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGALP
SESVEADQMLPAGLSTAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKID
WAFAELLALGSLVAEGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGT
PTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEA
KWGQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHAL
DGVQRPLIVFTPKSMLRNKAVVSDVKDFTEIKFRSVLEEPTYEDGIGDRSKVSRVLLTSG
KLYYELVARKAKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPSVQEYFWVQEEPANQGAW
PRFGLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFG
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacataagttcaccattcggtcaaaacgaatggctggtcgaggagatgtaccgc
aagttccgcgatgacccctcgtcggtggatccgagctggcacgagttcctcgtcgactac
aaccccgagccgacgggcgaggcggcgacggccaccccgaccagcggcgatggccgcccg
cccgcggcccccgccaagccggccgcggcggcccccgccaagccggccgcggcggccccc
gaaagccccaagcccgcgccccccgccagcacggcgccccccgtcagcacggccgccggc
aacggggtgccggcgcgccccgcgccggtgaaggccgccgcccccccgccggccgaaggc
gacgagttgcagacgctgcgcggcgccgcggcggccgtcgtcaagaacatgtcggcgtcg
ctggaggtgccgacggcgaccagcgtgcgcgccgttcccgccaagctgctgatcgacaac
cggatcgtcatcaacaaccaactcaagcgcacgcgcggcggcaagatctcgttcacccac
ctgctcgggtacgcgctggtgcaggcgatcaagaagttcccgaacatgaatcggcactac
gccgaggtcgacggcaaacccacggccgtcaccccggcgcacaccaacctgggcctagcg
atcgacctgcagggcaaggacggcaagcgttccttggtggtggccggcatcaagggctgc
gagaccatgcggttcgcgcagttcgtcaccgcctacgaagacatcgtgcggcgggcccgc
gacggcaagttgaccgccgaagactttgccggcgtgacgatttcgctgaccaacccgggc
accatcggcaccgtgcactcggtgccgcggctgatgaacggccagggcgccatcatcggc
gtcggcgccatggagtaccccgctgagttccagggcgccagcgaggaacgcatcgccgag
ctggggatcggcaagctgatcacgctgacctcgacctatgaccaccgcatcatccagggc
gcggaatccggcgacttcttgcgcacgatccacgagatgctgctctcggatgcgttctgg
gacgagatcttccgcgagctgggcaacccgtatctgccggtgcgctggagcaccgacaac
ccggactcgatcgtcgacaagaccgcccgggtgatggaattgattgcggcctaccgcaat
cgcggccacctgatggccgacatcgacccgctgcgcttggacggcagccggttccgcagc
caccccgacctcgagatcctcaaccacggcctgacgctgtgggatctcgatcgggtgttc
aaagtcaacggcttcgccggttccgagtacaagaagctgcgcgacgtgctgggcctgctg
cgcgatgcctactgccgccacatcggcgtggagtacacccacatcctcgatcccgagcag
caggagtggctgcagcagcgcgtcgagaccaagcacgtcaaaccgacggtggccgagcag
aagttcatcctgagcaaactgaacgcggccgaggccttcgagaccttcctgcagaccaaa
tacgttgggcagaaacggttttcactcgagggggcggaaagcatcattccgatgatggac
gcggcgatcgaccagtgcgccgagcacgggctcgacgaggtggtcatcgggatgccgcac
cgtggccggctcaacgtgctggccaacatcgtcggcaagccgtactcacagatcttttcg
gagttcgagggcaacctcaaccccgcgcaggcgcacggctccggcgacgtcaaataccac
ctgggcgccaccggcgtgtacctacagatgttcggcgacaacgacatccaggtgtcgctg
accgccaacccgtcgcacctggaagccgtcgacccggtgctggagggcctggtgcgcgcc
aagcaggacctgctggaccggcgggccgaggaccagggggacgacaaggccttctcggtg
gtgccgatgatgctgcacggcgacgcggcgttcgccggtcagggcgtggtcgccgagacc
ctcaacctgacccacctgcccggttaccgcgtcggcggcaccatccacatcatcgccaac
aaccagatcggcttcaccaccgcgccggagtactcacggtccagcgagtactgcaccgac
gtcgcgaaaatgatcggggcgccgatcttccacgtcaacggcgacgacccggaggcgtgc
gcgtgggtggccaagctggccgtcgacttccggcaggagttcaagaaggacgtcgtcatc
gacatgctgtgctaccgcaagcgcgggcacaacgaaggcgatgacccgtcgatgaccaac
cccgccatgtacgacgtcgtcgacatcaagcgcggggtccgcaagagctacaccgaagcc
ctgatcggccgcggcgacatctcgatgaaggaagccgaggacgccctgcgcgactaccag
ggccagctcgagcgggtgttcaacgaggtccgcgagctggagaagcacggcgcgctgccc
agcgaatcggtggaggccgaccagatgctgcccgcgggcctgtccaccgcggtggacaag
gcgctgctggcccgcatcggtgacgcgttcctggcgctacccgagggcttcacggcgcac
ccgcgggtgcagccggtcctggagaagcgccgggagatggcctacgagggcaagatcgac
tgggccttcgccgaactgctggcgctcggctcgctggtggccgagggcaagctggtgcgc
ctatcggggcaagacacccggcgcggcaccttctcgcagcgccactcggtgatcatcgac
cgcaacaccggcgaggagttcacgccgctgcagctgctggcgaccaaccccgacggcacc
cccaccggcggcaagttcctggtctacgactccccgctgtcggaatacgcggccgtcggc
ttcgagtacggctacaccgtgggcaacccggacgcgctcgtcctgtgggaagcccaattc
ggggacttcgtcaacggcgcgcagtcgatcatcgacgagttcatcagctccggcgaggcc
aagtggggccagctgtccaacgtggtgctgctgctgccgcacggccacgaaggccagggc
cccgaccacacctccggccgcatcgagcgcttcctgcagctgtgggcggagggttcgatg
acgatcgcgatgccctccacgccgtccaactatttccacttgttgcgccggcacgccctc
gacggggtgcagcgcccgctgatcgtgttcacgcccaagtcgatgctgcgcaacaaggcg
gtggtcagcgacgtcaaggacttcaccgagatcaagttccgctcggtgctcgaagagccg
acctacgaggacggcatcggcgatcgcagcaaggtcagcagggtcctgctgaccagcggc
aagctctactacgagttggtggcccgcaaggccaaggacaaccgggacgacgtggcgatc
gtgcggatcgagcagctcgccccgctgccgaagcgccggctgggcgaaacgctggaccgc
tacccgagcgtccaggagtacttctgggttcaggaagagccggccaaccagggcgcgtgg
ccgcgcttcggcctggaattgcccgagctgctgcccgacaagctgaccgggctcaagcgg
atttcccgccgggcgatgtcggccccgtcgtcgggctcgtcgaaggtgcacgccgtcgag
cagcaggagatcatcgacacggccttcggctga
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