Microbacterium sp. RG1: EHF32_01115
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Entry
EHF32_01115 CDS
T10164
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mice Microbacterium sp. RG1
Pathway
mice00020
Citrate cycle (TCA cycle)
mice00630
Glyoxylate and dicarboxylate metabolism
mice00785
Lipoic acid metabolism
mice01100
Metabolic pathways
mice01110
Biosynthesis of secondary metabolites
mice01120
Microbial metabolism in diverse environments
mice01200
Carbon metabolism
mice01210
2-Oxocarboxylic acid metabolism
Module
mice_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mice_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mice00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
EHF32_01115
00630 Glyoxylate and dicarboxylate metabolism
EHF32_01115
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EHF32_01115
Enzymes [BR:
mice01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
EHF32_01115
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
EHF32_01115
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
EHF32_01115
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
EHF32_01115
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Motif
Pfam:
2-oxoacid_dh
E1_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
SHOCT
Motif
Other DBs
NCBI-ProteinID:
QCQ15442
LinkDB
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Position
complement(248413..252087)
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AA seq
1224 aa
AA seq
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MSSQVTGVGVSNEGEFGANEWLVEELYEQFLVDRNSVDKSWWPVLEAYHSQAGSGGAAKA
APAASEPHPVTAPIPVIGSQPVARTTGKPAKPQPIPAQAPKAQPSDPAGEVQEDVVTTLK
GMTKTLAANMDESLTVPTATSVRTVPAKLMIDNRIVINNHMARTRGGKVSFTHLIGWALI
QALKEFPSQNVFYAEVDGKPSVVAPAHINLGIAIDLPKPDGTRALMVPSIKRAESLTFNE
FLASYEDLVKRARTNKLTAADFQGTTLSLTNPGGIGTVHSVPRLMKGQGCIIGAGALEYP
AEFQGSSEKTLVELGIGKTITLTSTYDHRVIQGAGSGEFLKKVHELLIGQRDFYEGIFAA
LRIPYAPIRWGSDINVDLAERIDKGARVQELINSFRVRGHLMADIDPLEYVQRTHPDLEI
ESHGLTFWDLDREFIVGGFGGKRQMKLRDILGVLRDSYCRTLGIEYMHIQDPVQRKWFQD
NVEVKYQKPGHDEQLRILSKLNQAEAFETFLQTKYVGQKRFSLEGSESVIPLLDEILQGA
ASAGLDGAAIGMAHRGRLNVLTNVAGKTYGQVFREFEGTSLPGNKRGSGDVKYHLGTEGT
FQSDAGTELPVILAANPSHLETVDGVLEGIVRAKQDRKPIGTFAWLPILVHGDAAFAGQG
VVVETLQMSQLRGYRTGGTVHVVINNQLGFTTLPVDGRTSVYATDVAKTIQAPILHVNGD
DPEAVVRAAELAFRYRQEFHRDIVIDLVSYRRRGHNEGDDPSMTQPLMTNLVEAKRSVRR
LYTESLVGRGDITEEEYEQAKRDFQDRLEVAFAETHEAETGTHPVVAESVEVERAVGEPE
TTGVSTDVVQLIGDAFVNKPDGFTVHAKLQQLLDKRHTMSRSGGIDWAFGELLAFGSLLV
EGTPVRLAGQDSRRGTFVQRHAVFHDRNNGQEWLPLTNLSEGQGRFFVYDSLLSEYAAVA
FEYGYSVERPDALVLWEAQFGDFANGAQTVIDTYLSSADQKWGQQSSVVLLLPHGYEGAG
PDHSSARIERFLQMCAQENMTVARPSTPASYFHLLRRQAYAQPRRPLVVFTPKAMLRLRD
AVSPVEAFTQGKFEPVLDDERGVDKNAVTRVLLHAGKIHWDLRSELDKNPDDRVALVRLE
QYYPAPIDELNAVIDRYPNAELVWVQEEPENQGAWPFIALEVVKHLHDRTIRVVSRAASA
SPAAGSAKMHQIEQAELLRRALTF
NT seq
3675 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgagccaggtgacgggcgtcggagtatcgaacgaaggagagttcggagccaatgag
tggctcgtcgaggaactctacgaacagttccttgtcgaccgtaactcggtcgacaagtct
tggtggccggtcctggaggcctaccactcccaggcgggatcgggcggtgccgccaaggca
gcacccgccgcatccgagccccacccggtgaccgcgccgatccccgtgatcggctcgcag
cccgtggcccgcacgaccggcaagccggccaagccgcagccgatcccggcgcaggccccc
aaggcccagccctccgacccggcgggcgaggtgcaggaggacgtcgtcacgaccctcaag
gggatgacgaagaccctcgccgccaacatggacgagtcgctgacggtgcccaccgcgacg
agcgttcgcaccgtccccgccaagctgatgatcgacaaccgcatcgtcatcaacaaccac
atggcgcggacccgtggcggcaaggtgagcttcacgcacctgatcgggtgggcgctcatc
caggcgctcaaggagttcccgagccagaacgtcttctacgccgaggtcgacggcaagccc
tcggtcgtcgctcccgcgcacatcaacctgggcatcgcgatcgatctccccaagcccgac
ggcacgcgcgcgctcatggtgccgagcatcaagcgcgcggagtcgctgacgttcaacgag
ttcctggcctcctacgaagacctggtcaagcgcgcccgcaccaacaagctgacggcggcc
gacttccagggcaccacgctctcgctcacgaatccgggcggcatcggcaccgtgcactcg
gtaccccgtctcatgaaggggcagggctgcatcatcggcgcgggcgccctcgagtacccg
gccgagttccagggctcgagcgagaagacgctcgtcgagctcggcatcggcaagacgatc
acgctcacgagcacctacgaccaccgcgtgatccagggcgccggctccggcgagttcctg
aagaaggtccacgagctgctgatcgggcagcgcgacttctacgagggcatcttcgcggcg
ctgcggatcccctacgcccccatccgctggggcagcgacatcaacgtcgacctcgcggag
cgcatcgacaagggtgcgcgcgtgcaggagctcatcaactcgttccgcgtccgcgggcac
ctgatggcggacatcgatccgcttgagtacgtgcagcgcacgcaccccgacctcgagatc
gagagccacgggctgaccttctgggacctcgaccgcgagttcatcgtcggcggcttcggc
ggcaagcgtcagatgaagctccgcgacatcctcggcgtgctgcgtgactcctactgccgc
accctcggcatcgagtacatgcacatccaggacccggtgcagcgcaagtggttccaggac
aacgtcgaggtgaagtaccagaagcccggccatgacgagcagctgcgcatcctttccaag
ctcaaccaggcagaggccttcgagacgttcctgcagaccaagtacgtcggccagaagcgc
ttcagcctggagggcagcgaatcggtcatccccctgctcgatgagatcctgcagggcgcg
gcctcggcgggtctcgacggcgccgccatcggtatggcgcaccgcggccgcctgaacgtc
ctgaccaacgtcgccggcaagacctacggccaggtcttccgcgagttcgagggcaccagc
ctccccggcaacaagcgcggctcgggcgatgtgaagtaccatctgggcaccgagggcacg
ttccagtcggatgcgggcacggagcttccggtgatcctcgccgccaacccctcgcacctc
gagaccgtcgacggcgtgctcgagggcatcgtccgcgccaagcaggaccgcaagccgatc
ggcaccttcgcctggcttcccatcctcgtccacggcgacgcggccttcgcgggccagggc
gtcgtcgtcgagacgctccagatgtcgcagctgcgcgggtaccgcaccggcggcaccgtg
cacgtcgtgatcaacaaccagctcggcttcacgacgctgcccgtcgacggacgcacctcg
gtctacgcgacggatgtggccaagaccatccaggctcccatcctccacgtgaacggcgac
gaccccgaggccgtcgtgcgcgcggccgaactcgccttccggtaccgccaggagttccac
cgcgacatcgtcatcgacctcgtcagctaccgccgccgcggtcacaacgagggcgacgac
ccgtcgatgacgcagccgctcatgacgaacctcgtcgaggcgaagcgctccgtgcgccgc
ctctacacggagtcgctagtgggtcgcggcgacatcaccgaggaagagtacgagcaggcc
aagcgcgacttccaggatcgcctcgaggtggcgttcgccgagacgcacgaggccgagacc
ggcacgcaccccgtcgtcgccgagagcgtcgaggtcgagcgggccgtcggcgagccggag
acgacaggcgtgtcgaccgacgtcgtgcagctgatcggcgacgccttcgtgaacaagccc
gacggcttcacggtgcacgccaagctccagcaactgctcgacaagcggcacaccatgagc
cgctcgggcggcatcgattgggctttcggcgagttgctcgcgttcggctcgctcctcgtc
gaggggactcccgtgcgcctggcgggccaggactcccgtcgtggaacgttcgtgcagcgc
cacgccgtgttccacgatcgcaacaacggtcaggaatggctgccgctgacgaatctcagc
gagggccagggacgcttcttcgtctacgactcgctgctcagtgagtatgcggccgtcgcg
ttcgagtacggctactcggtcgagcgcccggacgcgcttgtgctgtgggaggcgcagttc
ggcgacttcgccaacggcgcacagactgtgatcgacacctacctctcgtcggccgaccag
aagtggggccagcagtcgagcgtcgtgctgttgctgcctcacggatacgagggcgccggt
cccgaccactcctccgctcgcatcgagcgcttcctgcagatgtgcgcgcaggagaacatg
accgtcgcgcgcccgtcgacacccgcctcctacttccacctgctgcgccgccaggcttac
gcgcagccgcgccgaccgctcgtcgtgttcaccccgaaggcgatgctgcgtcttcgtgac
gcggtgagccccgtcgaggcgttcacgcagggcaagttcgagccggtgctggacgacgag
cgcggcgtcgacaagaacgccgtcacgcgggtgctgttgcacgccggcaagatccactgg
gacctgcgctcggagctcgacaagaaccccgatgaccgcgtggcgctggtgcgcctcgag
cagtactaccccgcgccgatcgacgagctgaacgcggtcatcgaccgctacccgaacgcg
gaactcgtgtgggtccaggaagagcccgagaaccagggcgcgtggccgttcatcgccctc
gaggtcgtcaagcatctgcacgaccgcacgatccgcgtggtctcccgggccgcatccgcc
tccccggcggccggctcggcgaagatgcatcagatcgagcaggcggagctgctgcgccgc
gcactcacgttctga
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