KEGG   Micromonospora sp. HM134: FJK98_19485
Entry
FJK98_19485       CDS       T06145                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mich  Micromonospora sp. HM134
Pathway
mich00270  Cysteine and methionine metabolism
mich00450  Selenocompound metabolism
mich00670  One carbon pool by folate
mich01100  Metabolic pathways
mich01110  Biosynthesis of secondary metabolites
mich01230  Biosynthesis of amino acids
mich04980  Cobalamin transport and metabolism
mich04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:mich00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    FJK98_19485 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    FJK98_19485 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    FJK98_19485 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    FJK98_19485 (metH)
   04980 Cobalamin transport and metabolism
    FJK98_19485 (metH)
Enzymes [BR:mich01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     FJK98_19485 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CM_2
Other DBs
NCBI-ProteinID: QDY11765
UniProt: A0A518WRA4
LinkDB
Position
complement(4546701..4550204)
AA seq 1167 aa
MRDVLADRILIADGAMGTMLQAADLSLDDFEGLEGCNEILNVTRPDVVRGVHEAYLAAGA
DCVETNTFGANLANLAEYDIPQRIRELSEAGARIAREVADAYATAQRPRFVLGSIGPGTK
LPTLGHAPYATLRDAYQENAAGLIAGGSDALIIETCQDLLQVKAAVVGSKRAMAELGQQV
PIICHVAVETTGTMLVGSEIGAALAAIEPLGVDLIGLNCSTGPAEMGEHLRYLSQHSRIP
LSVMPNAGLPVLTADGAYFPLSPVELADALERFVADYGVGLIGGCCGTTPEHIRALAERL
HGATPAAREPRHEAGVSSIYHPVPFAQDASVLMVGERTNANGSKAFRESMLAADWQACVE
VARSQARDGSHLLDLCVDYVGRDGTQDMRELAGRFATASTLPIMLDSTEPAVIEAGLEML
GGRCVVNSVNFEDGDGPDSRYARVMPVIAEHGAAVVALLIDEEGQARTREWKVRVAARLI
DDLTGRWGMDRSDILIDALTFPIATGQEETRRDGIETIEAIREIAARYPGVNFTLGISNV
SFGLNPAARQVLNSVFLHECVQAGLTSAIVHASKILPMSKIPEAQREVALDLIYDRRREG
YDPVQRFIEAFEGVDAASARATRAEELAGLPLDERLKRRIIDGERNGLEADLDTAMAQGR
SPLSIINDILLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEAVEDGGKGRI
VLATVRGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIGAILDAAEEHRADAIGMSGLLVK
STVIMKENLAEMASRGVAERWPVLLGGAALTRAYVEDDLRAMFPGQVHYARDAFEGLALM
DRVMTAKRGGAPVIDPEREAALAARRARREKQRTMVTEVLPELHDSSVRSDVATDVGVPT
PPFFGTRVVKGVPLAEYAALLDERATFLGQWGLRGSRGGQGPSYEELVETEGRPRLRYWL
DRLIADQVLEAAVVYGYFPAYSEGNDLVVLDENGNSERARFSFPRQRQERRLCLADFFRP
KDDGLDVVALQLVTVGQPISDYTAKMFAANEYRDYLEVHGLSVQLTEALAEYWHRRIRSE
LTLPGGGTVATGDPTDLAGLLRNDYRGCRYAFGYPACPDLEDRAKIVELLGAERIGVQLS
EEFQLVPEQATDAIVVHHPEANYFNAK
NT seq 3504 nt   +upstreamnt  +downstreamnt
ttgcgggatgtgctggccgaccggattctcatcgccgacggcgcgatggggacaatgctc
caggctgccgacctgagcctcgacgacttcgaggggctggaaggctgcaacgagatcctc
aacgtgacccggcccgacgtggtgcgcggcgtgcacgaggcctacctggcggccggcgcg
gactgcgtcgagacgaacacgttcggcgcgaacctcgccaacctcgccgagtacgacatc
ccgcagcgcatccgggagctgtccgaggccggcgcgcggatcgcccgggaggtcgccgac
gcgtacgccacggcgcagcgcccccggttcgtgctcggctcgatcggccccggcaccaag
ctgcccaccctcggccacgccccgtacgcgacgttgcgcgacgcgtaccaggagaacgcg
gccgggctcatcgccggtgggtcggacgcgctgatcatcgagacctgccaggacctgttg
caggtcaaggcggccgtggtcgggtcgaagcgggcgatggccgagctgggccagcaggtg
ccgatcatctgtcacgtggccgtggagaccaccggcaccatgctggtgggcagcgagatc
ggggcggcgctggcggccatcgagccgctgggggtggacctgatcgggctgaactgctcg
accggcccggccgagatgggcgagcacctgcgctacctgtcgcagcactcccggattccg
ctgtcggtgatgccgaacgcgggcctgccggtgctgaccgccgacggggcgtacttcccg
ctgagcccggtggagctggccgacgccctggaacggttcgtggccgactacggcgtgggg
ctgatcggtggctgctgcggcaccaccccggagcacatccgggcgttggccgagcggttg
cacggcgcgaccccggcggcgcgggagccccggcacgaggcgggtgtctcgtcgatctac
cacccggtgccgttcgcccaggacgcctcggtgctgatggtgggggaacggaccaacgcc
aacggctccaaggcgttccgtgagtcgatgctcgccgccgactggcaggcgtgcgtcgag
gtggcccgcagccaggcccgcgacggctcgcacctgctggacctgtgcgtcgactacgtc
ggccgggacggcacgcaggacatgcgggagctggccggccggttcgccaccgcgtccacc
ctgccgatcatgctggactccaccgagccggcggtgatcgaggccgggttggagatgctc
ggcgggcgttgcgtggtcaactcggtcaacttcgaggacggcgacggccccgactcccgc
tacgcgcgggtgatgccggtgatcgccgagcacggggcggccgtggtggcgctgctcatc
gacgaggaggggcaggcccgtacccgggagtggaaggtccgggtggcggcccggctgatc
gacgacctgaccggccggtgggggatggaccggtcggacatcctcatcgacgcgctgacc
ttcccgatcgccaccggccaggaggagacccgccgggacggcatcgagacgatcgaggcg
atccgggagatcgccgcccgctacccgggggtcaacttcaccctgggcatctcgaacgtc
tcgttcgggctcaacccggcggcccggcaggtgctcaactcggtgttcctgcacgagtgc
gtgcaggccgggctgacctcggcgatcgtgcacgccagcaagatcctgccgatgtcgaag
atccccgaggcgcagcgcgaggtcgccctcgacctgatctacgaccggcggcgcgagggc
tacgacccggtgcagcggttcatcgaggcgttcgagggcgtcgacgccgcgtcggcgcgg
gccacccgggccgaggagctggccgggctgccgttggacgaacggctcaagcggcggatc
atcgacggcgagcgcaacggcctggaggccgacctggacaccgcgatggcgcagggccgg
tccccgctgtccatcatcaacgacatcctgctcgacggcatgaaggtcgtcggtgagctg
ttcggctccgggcagatgcagttgccgttcgtgctccagtccgccgaggtgatgaagacg
gcggtggcctacctggagccgcacatggaggcggtcgaggacggcggcaagggccggatc
gtgctggccaccgtacgcggcgacgtgcacgacatcggcaagaacctggtcgacatcatc
ctgtccaacaacggctacgaggtcgtcaacatcggcatcaagcagccgatcggcgcgatc
ctcgacgccgccgaggagcaccgggccgatgcgatcgggatgtccgggctgctggtcaag
agcacggtcatcatgaaggagaacctcgccgagatggcgtcgcgcggggtcgccgagcgg
tggccggtgctgttgggcggggcggcgctgacccgcgcgtacgtcgaggacgacctgcgg
gcgatgttccccggccaggtccactacgcgcgggacgccttcgaggggctggccctgatg
gaccgggtgatgaccgccaagcgtggcggcgcacccgtgatcgacccggagcgggaggcg
gccctggcggcccggcgggcccgccgggagaagcagcgcacgatggtcaccgaggtgctg
ccggaactgcacgactcctcggtccgctccgacgtggccaccgacgtgggggtgcccacc
ccgccgttcttcggcacccgggtggtcaagggggtgccgctggccgagtacgcggcgctg
ctggacgaacgggccaccttcctcggccagtgggggctgcgcgggtcgcggggcggccag
ggcccgtcgtacgaggaactggtggagaccgaggggcggccccggctgcgctactggctg
gaccggctcatcgccgaccaggtgctggaggcggccgtggtgtacggctacttcccggcg
tactccgagggcaacgacctggtggtgctggacgagaacggcaacagcgagcgggcccgg
ttctcgttcccccggcagcggcaggagcggcggctctgcctggccgacttcttccgcccg
aaggacgacgggctcgacgtggtggcgttgcagctggtcaccgtcggccagccgatcagc
gactacaccgcgaagatgttcgccgccaacgagtaccgcgactacctggaggtgcacggg
ttgtcggtgcagctcaccgaggcgctcgccgagtactggcaccggcgtatccgctccgag
ctgaccctgccgggcggcggcacggtcgccaccggcgacccgaccgaccttgccgggctg
ctgcgcaacgactaccggggctgccggtacgcgttcggctacccggcctgcccggatctg
gaggaccgggcgaagatcgtggagctgctcggggcggagcggatcggggtgcagttgtcg
gaggagttccagctggtgccggagcaggccaccgacgcgatcgtggtgcaccacccggag
gcgaactacttcaacgccaagtga

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