Micromonospora sp. HM134: FJK98_19485
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Entry
FJK98_19485 CDS
T06145
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00270
Cysteine and methionine metabolism
mich00450
Selenocompound metabolism
mich00670
One carbon pool by folate
mich01100
Metabolic pathways
mich01110
Biosynthesis of secondary metabolites
mich01230
Biosynthesis of amino acids
mich04980
Cobalamin transport and metabolism
mich04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FJK98_19485 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
FJK98_19485 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
FJK98_19485 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
FJK98_19485 (metH)
04980 Cobalamin transport and metabolism
FJK98_19485 (metH)
Enzymes [BR:
mich01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
FJK98_19485 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
CM_2
Motif
Other DBs
NCBI-ProteinID:
QDY11765
UniProt:
A0A518WRA4
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All DBs
Position
complement(4546701..4550204)
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AA seq
1167 aa
AA seq
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MRDVLADRILIADGAMGTMLQAADLSLDDFEGLEGCNEILNVTRPDVVRGVHEAYLAAGA
DCVETNTFGANLANLAEYDIPQRIRELSEAGARIAREVADAYATAQRPRFVLGSIGPGTK
LPTLGHAPYATLRDAYQENAAGLIAGGSDALIIETCQDLLQVKAAVVGSKRAMAELGQQV
PIICHVAVETTGTMLVGSEIGAALAAIEPLGVDLIGLNCSTGPAEMGEHLRYLSQHSRIP
LSVMPNAGLPVLTADGAYFPLSPVELADALERFVADYGVGLIGGCCGTTPEHIRALAERL
HGATPAAREPRHEAGVSSIYHPVPFAQDASVLMVGERTNANGSKAFRESMLAADWQACVE
VARSQARDGSHLLDLCVDYVGRDGTQDMRELAGRFATASTLPIMLDSTEPAVIEAGLEML
GGRCVVNSVNFEDGDGPDSRYARVMPVIAEHGAAVVALLIDEEGQARTREWKVRVAARLI
DDLTGRWGMDRSDILIDALTFPIATGQEETRRDGIETIEAIREIAARYPGVNFTLGISNV
SFGLNPAARQVLNSVFLHECVQAGLTSAIVHASKILPMSKIPEAQREVALDLIYDRRREG
YDPVQRFIEAFEGVDAASARATRAEELAGLPLDERLKRRIIDGERNGLEADLDTAMAQGR
SPLSIINDILLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEAVEDGGKGRI
VLATVRGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIGAILDAAEEHRADAIGMSGLLVK
STVIMKENLAEMASRGVAERWPVLLGGAALTRAYVEDDLRAMFPGQVHYARDAFEGLALM
DRVMTAKRGGAPVIDPEREAALAARRARREKQRTMVTEVLPELHDSSVRSDVATDVGVPT
PPFFGTRVVKGVPLAEYAALLDERATFLGQWGLRGSRGGQGPSYEELVETEGRPRLRYWL
DRLIADQVLEAAVVYGYFPAYSEGNDLVVLDENGNSERARFSFPRQRQERRLCLADFFRP
KDDGLDVVALQLVTVGQPISDYTAKMFAANEYRDYLEVHGLSVQLTEALAEYWHRRIRSE
LTLPGGGTVATGDPTDLAGLLRNDYRGCRYAFGYPACPDLEDRAKIVELLGAERIGVQLS
EEFQLVPEQATDAIVVHHPEANYFNAK
NT seq
3504 nt
NT seq
+upstream
nt +downstream
nt
ttgcgggatgtgctggccgaccggattctcatcgccgacggcgcgatggggacaatgctc
caggctgccgacctgagcctcgacgacttcgaggggctggaaggctgcaacgagatcctc
aacgtgacccggcccgacgtggtgcgcggcgtgcacgaggcctacctggcggccggcgcg
gactgcgtcgagacgaacacgttcggcgcgaacctcgccaacctcgccgagtacgacatc
ccgcagcgcatccgggagctgtccgaggccggcgcgcggatcgcccgggaggtcgccgac
gcgtacgccacggcgcagcgcccccggttcgtgctcggctcgatcggccccggcaccaag
ctgcccaccctcggccacgccccgtacgcgacgttgcgcgacgcgtaccaggagaacgcg
gccgggctcatcgccggtgggtcggacgcgctgatcatcgagacctgccaggacctgttg
caggtcaaggcggccgtggtcgggtcgaagcgggcgatggccgagctgggccagcaggtg
ccgatcatctgtcacgtggccgtggagaccaccggcaccatgctggtgggcagcgagatc
ggggcggcgctggcggccatcgagccgctgggggtggacctgatcgggctgaactgctcg
accggcccggccgagatgggcgagcacctgcgctacctgtcgcagcactcccggattccg
ctgtcggtgatgccgaacgcgggcctgccggtgctgaccgccgacggggcgtacttcccg
ctgagcccggtggagctggccgacgccctggaacggttcgtggccgactacggcgtgggg
ctgatcggtggctgctgcggcaccaccccggagcacatccgggcgttggccgagcggttg
cacggcgcgaccccggcggcgcgggagccccggcacgaggcgggtgtctcgtcgatctac
cacccggtgccgttcgcccaggacgcctcggtgctgatggtgggggaacggaccaacgcc
aacggctccaaggcgttccgtgagtcgatgctcgccgccgactggcaggcgtgcgtcgag
gtggcccgcagccaggcccgcgacggctcgcacctgctggacctgtgcgtcgactacgtc
ggccgggacggcacgcaggacatgcgggagctggccggccggttcgccaccgcgtccacc
ctgccgatcatgctggactccaccgagccggcggtgatcgaggccgggttggagatgctc
ggcgggcgttgcgtggtcaactcggtcaacttcgaggacggcgacggccccgactcccgc
tacgcgcgggtgatgccggtgatcgccgagcacggggcggccgtggtggcgctgctcatc
gacgaggaggggcaggcccgtacccgggagtggaaggtccgggtggcggcccggctgatc
gacgacctgaccggccggtgggggatggaccggtcggacatcctcatcgacgcgctgacc
ttcccgatcgccaccggccaggaggagacccgccgggacggcatcgagacgatcgaggcg
atccgggagatcgccgcccgctacccgggggtcaacttcaccctgggcatctcgaacgtc
tcgttcgggctcaacccggcggcccggcaggtgctcaactcggtgttcctgcacgagtgc
gtgcaggccgggctgacctcggcgatcgtgcacgccagcaagatcctgccgatgtcgaag
atccccgaggcgcagcgcgaggtcgccctcgacctgatctacgaccggcggcgcgagggc
tacgacccggtgcagcggttcatcgaggcgttcgagggcgtcgacgccgcgtcggcgcgg
gccacccgggccgaggagctggccgggctgccgttggacgaacggctcaagcggcggatc
atcgacggcgagcgcaacggcctggaggccgacctggacaccgcgatggcgcagggccgg
tccccgctgtccatcatcaacgacatcctgctcgacggcatgaaggtcgtcggtgagctg
ttcggctccgggcagatgcagttgccgttcgtgctccagtccgccgaggtgatgaagacg
gcggtggcctacctggagccgcacatggaggcggtcgaggacggcggcaagggccggatc
gtgctggccaccgtacgcggcgacgtgcacgacatcggcaagaacctggtcgacatcatc
ctgtccaacaacggctacgaggtcgtcaacatcggcatcaagcagccgatcggcgcgatc
ctcgacgccgccgaggagcaccgggccgatgcgatcgggatgtccgggctgctggtcaag
agcacggtcatcatgaaggagaacctcgccgagatggcgtcgcgcggggtcgccgagcgg
tggccggtgctgttgggcggggcggcgctgacccgcgcgtacgtcgaggacgacctgcgg
gcgatgttccccggccaggtccactacgcgcgggacgccttcgaggggctggccctgatg
gaccgggtgatgaccgccaagcgtggcggcgcacccgtgatcgacccggagcgggaggcg
gccctggcggcccggcgggcccgccgggagaagcagcgcacgatggtcaccgaggtgctg
ccggaactgcacgactcctcggtccgctccgacgtggccaccgacgtgggggtgcccacc
ccgccgttcttcggcacccgggtggtcaagggggtgccgctggccgagtacgcggcgctg
ctggacgaacgggccaccttcctcggccagtgggggctgcgcgggtcgcggggcggccag
ggcccgtcgtacgaggaactggtggagaccgaggggcggccccggctgcgctactggctg
gaccggctcatcgccgaccaggtgctggaggcggccgtggtgtacggctacttcccggcg
tactccgagggcaacgacctggtggtgctggacgagaacggcaacagcgagcgggcccgg
ttctcgttcccccggcagcggcaggagcggcggctctgcctggccgacttcttccgcccg
aaggacgacgggctcgacgtggtggcgttgcagctggtcaccgtcggccagccgatcagc
gactacaccgcgaagatgttcgccgccaacgagtaccgcgactacctggaggtgcacggg
ttgtcggtgcagctcaccgaggcgctcgccgagtactggcaccggcgtatccgctccgag
ctgaccctgccgggcggcggcacggtcgccaccggcgacccgaccgaccttgccgggctg
ctgcgcaacgactaccggggctgccggtacgcgttcggctacccggcctgcccggatctg
gaggaccgggcgaagatcgtggagctgctcggggcggagcggatcggggtgcagttgtcg
gaggagttccagctggtgccggagcaggccaccgacgcgatcgtggtgcaccacccggag
gcgaactacttcaacgccaagtga
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