Micromonospora sp. HM134: FJK98_24870
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Entry
FJK98_24870 CDS
T06145
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00010
Glycolysis / Gluconeogenesis
mich00020
Citrate cycle (TCA cycle)
mich00620
Pyruvate metabolism
mich00785
Lipoic acid metabolism
mich01100
Metabolic pathways
mich01110
Biosynthesis of secondary metabolites
mich01120
Microbial metabolism in diverse environments
mich01200
Carbon metabolism
mich01210
2-Oxocarboxylic acid metabolism
Module
mich_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FJK98_24870 (aceE)
00020 Citrate cycle (TCA cycle)
FJK98_24870 (aceE)
00620 Pyruvate metabolism
FJK98_24870 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FJK98_24870 (aceE)
Enzymes [BR:
mich01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FJK98_24870 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QDY09985
UniProt:
A0A518WL57
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Position
5760865..5763603
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AA seq
912 aa
AA seq
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MATERKRPVITAGLPSQLPDIDPEETGEWVESLDGVIDERGTKRARYVMLSLLERARERQ
VGVPSLTTTDYINTIAPEQEPWFPGDEHIERRIRAYVRWNAAMLVHRAQRPEIGVGGHIS
TFASSASLYEVGFNHFFRGKNHPGGGDHIFYQGHASPGMYGRAFLEGRLSENQLDGFRQE
LSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNRYLQHRGIKDTSQQHVWA
FLGDGEMDEVESLGAIGVAAREELDNLTFVINCNLQRLDGPVRGNGKIMQELEAFFRGAG
WNVIKVVWGREWDPLLAADTDGALVNLMNTTPDGDYQTYKAESGAYVREHFFGRDQRTRK
MVEHLSDDEIWNLKRGGHDYRKLYAAYKAATEHTGQPTVILAKTIKGWTLGSHFEGRNAT
HQMKKLTLDDLKLFRDRLYLDIPDKVLEENPYLPPYYTPGESSDELAYLRERREQLGGYL
PTRRTSHKKLAIPGPERFADVKRGSGKQKVATTMAFVRLLKDIMKDKEFGKRWVPIIPDE
ARTFGLDSIFPTAKIYSPHGQRYTSVDRELFLSYKESTTGQILHEGINEAGSVASFTAAG
TSYATHDEPMIPMYIFYSMFGFQRTGDGFWAAADQMARGFVLGATAGRTTLNGEGLQHED
GHSLLLAATNPAVVAYDAAFGFELAHIVENGLHRMYGEAQENVFYYLTVYNEPIHQPVEP
SDVDVDGLLKGIYRYAAAPQVDGPKANILASGTGMQWALKAQQLLAQDWGVAADVWSVTS
WTELRRDAVLCEEHNLLNPGAEQRVPYIQQKLADADGPKVAVSDWMRAVPDLIARWVPGD
YTSLGTDGFGMSDTRHALRRHFHVDAESVAVATLRQLALRGTVPAGVPAEAAKKYAIDDV
NAAPVGETGGDS
NT seq
2739 nt
NT seq
+upstream
nt +downstream
nt
gtggctacggaacgcaagcgcccggtgatcaccgctggtctgccgagccagcttccggac
atcgaccctgaagagaccggcgaatgggtcgagtcgctcgacggtgtcatcgacgagcgc
ggaaccaagcgcgcccggtacgtcatgctgagcctgctggagcgggcccgtgagcggcag
gtcggggttccgtccctgaccaccaccgactacatcaacaccatcgccccggagcaggaa
ccctggttcccgggtgacgagcacatcgagcggcggatccgggcgtacgtccggtggaac
gcggcgatgctggtgcaccgggcgcagcggccggagatcggcgtcggcgggcacatctcc
accttcgccagctccgcctccctctacgaggtgggcttcaaccacttcttccggggcaag
aaccacccgggcggtggcgaccacatcttctaccagggccacgcctcccccggcatgtac
gggcgggcgttcctggagggccggctctccgagaaccagctcgacgggttccggcaggag
ctgtcgcacccgggcggcgggctgccgtcgtacccgcacccgcggctgatgccggacttc
tgggagttccccacggtctccatgggcctgggcccgatgaacgcgatctatcaggcccgg
ttcaaccgctacctccagcaccggggcatcaaggacacctcccagcagcacgtctgggcg
ttcctcggtgacggcgagatggacgaggtcgagtcgctcggcgcgatcggcgtggccgcc
cgcgaggagctggacaacctcaccttcgtgatcaactgcaacctccagcggctggacggg
ccggtccgcggcaacggcaagatcatgcaggagctggaggcgttcttccggggggccggc
tggaacgtgatcaaggtggtctggggccgggagtgggacccgctgctcgccgcggacacc
gacggcgcgctggtcaacctgatgaacaccacccccgacggtgactaccagacctacaag
gcggagtccggggcgtacgtgcgggagcacttcttcggccgcgaccagcggacccgcaag
atggtcgagcacctgtccgacgacgagatctggaacctcaagcggggcgggcacgactac
cgcaagctctacgcggcctacaaggcggccaccgagcacaccgggcagccgaccgtgatc
ctggccaagaccatcaagggctggacgctgggctcgcacttcgagggccgcaacgccacg
caccagatgaagaagctgacgctggacgacctgaagctgttccgcgaccgcctctacctg
gacatcccggacaaggtcctggaggagaacccgtacctgccgccgtactacaccccgggc
gagtcctcggacgagctggcctacctgcgggagcggcgggagcagctcggcggctacctg
ccgacccgacggaccagccacaagaagctggcgatcccggggccggagcggttcgccgac
gtcaagcgcggctcgggcaagcagaaggtggccaccacgatggccttcgtccgcctgctc
aaggacatcatgaaggacaaggagttcggcaagcgctgggtgccgatcatcccggacgag
gcacgcaccttcggcctcgactcgatcttcccgaccgcgaagatctactcgccgcacggc
cagcggtacacctcggtcgaccgggagctgttcctgtcgtacaaggagtcgaccaccggg
cagatcctgcacgaggggatcaacgaggccggttcggtcgcctcgttcaccgccgccggc
acctcgtacgccacccacgacgagccgatgatcccgatgtacatcttctactcgatgttc
gggttccagcgcaccggtgacggcttctgggcggcggccgaccagatggcccggggcttc
gtcctcggcgcgaccgccggccggaccacgctcaacggtgagggcctccagcacgaggac
ggccactccctgctgctggccgccaccaacccggcggtggtcgcctacgacgcggcgttc
gggttcgagctggcccacatcgtggagaacggcctgcaccggatgtacggcgaggcgcag
gagaacgtcttctactacctcaccgtctacaacgagccgatccaccagccggtcgagccg
tccgacgtggacgtcgacgggctgctcaagggcatctaccggtacgcggcggccccgcag
gtcgacggcccgaaggcgaacatcctggcctccggcaccggcatgcagtgggccctcaag
gcccagcagctgctcgcccaggactggggggtggccgccgacgtctggtcggtgacctcc
tggacggagctgcgccgcgacgcggtgctctgcgaggagcacaacctgctcaacccgggc
gcggagcagcgggtgccgtacatccagcagaagctggccgacgccgacggcccgaaggtc
gcggtcagcgactggatgcgcgcggtaccggacctgatcgcccgctgggtaccgggcgac
tacacctcgctcggcaccgacggcttcggcatgtcggacacccggcacgcgctgcggcgg
cacttccacgtcgacgccgagtcggtggcggtggcgacgctgcggcagctcgccctgcgc
ggcacggtgccggccggcgtcccggccgaggccgccaagaagtacgcgatcgacgacgtc
aacgccgccccggtcggcgagaccggcggggacagctag
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