Micromonospora sp. HM134: FJK98_27280
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Entry
FJK98_27280 CDS
T06145
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00020
Citrate cycle (TCA cycle)
mich00630
Glyoxylate and dicarboxylate metabolism
mich00785
Lipoic acid metabolism
mich01100
Metabolic pathways
mich01110
Biosynthesis of secondary metabolites
mich01120
Microbial metabolism in diverse environments
mich01200
Carbon metabolism
mich01210
2-Oxocarboxylic acid metabolism
Module
mich_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mich_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
FJK98_27280
00630 Glyoxylate and dicarboxylate metabolism
FJK98_27280
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FJK98_27280
Enzymes [BR:
mich01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
FJK98_27280
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
FJK98_27280
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
FJK98_27280
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
FJK98_27280
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
OHCU_decarbox
SHOCT-like_DUF2089-C
Motif
Other DBs
NCBI-ProteinID:
QDY10392
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Position
6296832..6300605
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AA seq
1257 aa
AA seq
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MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDSAWHDFFADYRPAPGAATPRPAD
GKAAPAATPEPAEQQEPVATVATGPAAKAATATTKPAATAKPAAAPKPAAAKTATRSAAK
PAATEKAAPVKPAAKAPTASAAGTTPLRGVAARIVQNMDASLSVPTATSVRAVPAKLLVD
NRIVINNHLARGRGGKVSFTHLIGYALVRAVVEHPELNNSYAEVDGKPAMVRPEHVNLGI
AIDLTKPDGTRNLVVPSIKGCEQMDFRQFWQAYEDVVRRARRNELTMEDHSGTTISLTNP
GGIGTVHSIPRLMQGQSAIIGVGAMEYPAPYQGMSEATLAELAVSKIITLTSTYDHRIIQ
GAQSGEFLKVMHELMLGERGFYDQIFTSLRIPYEPVRWVRDVAVDSEGQINKTARVHELI
HAYRVRGHLMADTDPLEFTIRKHPDLDVLQHGLTLWDLDRTFPVNGFAGKQRMKLREILG
VLRDSYCRRLGIEYMHIQDPEERRWIQERIERRYEKPAADEQKHVLNRLNAAEAFETFLQ
TKYVGQKRFSLEGGESLIPLLGEVLEASAEDGLDEVVIGMAHRGRLNVLANIVGKPYEKI
FSEFEGHLDPRSTQGSGDVKYHLGQNGKFTTPDGDHSVKVSVVANPSHLEAVDPVLEGIV
RAKQDRIDLKLEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVG
FTTAPEYSRSSLYSTDVARMIQAPIFHVNGDDPETVVRVARLAFEYRQAFNKDVVIDMVC
YRRRGHNEGDDPSMSNPQMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQSQLE
RVFKATRDAATTPRQVGRPSRQEEPEPQVQTATDAAVVKAIGEAHVNLPEGFTPHKRIQQ
LLDRRAKMSVEGNIDWGYGEIIAFGALLHDGITVRLAGQDSRRGTFVQRHASIVDAKTGE
DHLPLKSLTADGERSRFFVHDSLLSEYAAMGFEYGYSVENVNALVCWEAQFGDFVNGAQS
VIDEFISSGEVKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQMCAEDNMRVAIPTTPA
NYFHLLRRQALSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFAPVLADTAAPAPEQVK
RVLLCSGKVYYDLFQARQERGVTDTAIIRIEQLYPLPVQEIRDALAAYPNAEDFAWVQEE
PANQGAWSFVALNLLEHLTDVRLRRISRPAAAAPAVGSAKMHEVEQTALIDAALPRP
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgctacctcgccgacccgtcgagcgtcgactcggcctgg
cacgacttcttcgccgactaccgacccgcccccggcgccgcgaccccgcgtccggctgac
ggcaaggccgcgccggccgcgacgccggagccggccgagcagcaggagccggtcgccacc
gtcgcgaccgggcccgccgcgaaggcggcgacggccaccaccaagccggccgccaccgcc
aagccggccgccgcgccgaagccggccgccgcgaagaccgccaccaggtccgccgcgaag
ccggcggccacggagaaggccgccccggtcaagccggcggcgaaggcgccgacggccagc
gccgccggcaccacgccgctgcgcggggtggccgcccggatcgtgcagaacatggacgcc
tcgctgtccgtgccgaccgccaccagcgtgcgcgcggtcccggccaagctgctggtcgac
aaccgcatcgtgatcaacaaccacctcgcccgggggcgcggtggcaaggtcagcttcacc
cacctgatcgggtacgcgctggtccgcgccgtggtcgagcacccggagctgaacaactcc
tacgccgaggtcgacggcaagccggcgatggtccgcccggagcacgtcaacctgggcatc
gccatcgacctgaccaagcccgacggcacccgcaacctggtggtgccgtccatcaagggc
tgcgagcagatggacttccggcagttctggcaggcgtacgaggacgtggtccggcgcgcc
cgccgcaacgagctgaccatggaggaccactccggtacgacgatctcgctgaccaacccg
ggcggcatcggcacggtgcactcgatcccccggctgatgcaggggcagagcgcgatcatc
ggggtcggcgcgatggagtaccccgcgccgtaccaggggatgagcgaggcgaccctggcc
gagctggcggtcagcaagatcatcacgctgaccagcacgtacgaccaccggatcatccag
ggcgcgcagtccggcgagttcctcaaggtgatgcacgagctgatgctcggcgagcgcggc
ttctacgaccagatcttcacctcgctgcgcatcccgtacgagccggtgcgctgggtgcgg
gacgtggccgtcgactccgaaggccagatcaacaagaccgcgcgggtgcacgagctgatc
cacgcctaccgggtccggggccacctgatggccgacaccgacccgctggagttcaccatc
cgcaagcaccccgacctggacgtcctccagcacgggctgaccctgtgggacctcgaccgc
accttcccggtcaacggcttcgccggcaagcagcggatgaagctgcgcgagatcctcggc
gtgctccgtgactcgtactgccggcggctcggcatcgagtacatgcacatccaggacccg
gaggagcgccgctggatccaggagcggatcgagcgccgttacgagaagccggccgccgat
gagcagaagcacgtgctcaaccggctcaacgccgccgaggcgttcgagaccttcctgcag
accaagtacgtcggccagaagcggttctcgctggagggcggcgagtcgctgatcccgctg
ctcggcgaggtgctggaggcgtccgccgaggacgggctggacgaggtcgtcatcggcatg
gcgcaccggggccggctcaacgtgctggccaacatcgtcggcaagccgtacgagaagatc
ttctcggagttcgaggggcacctcgacccgcggtccacccagggttcgggtgacgtgaag
taccacctgggccagaacggcaagttcaccaccccggacggcgaccactcggtcaaggtg
tcggtggtggcgaacccgtcgcacctggaggcggtggacccggtgctggagggcatcgtc
cgggccaagcaggaccggatcgacctcaagctggagggttacaccgtgctgccgctggcg
gtgcacggtgacgccgcgttcgccgggcagggggtcgtcgccgagacgctcaacctgtcc
cagctgcgcggctaccgcaccggcggcaccgtgcacgtggtggtcaacaaccaggtcggt
ttcaccaccgccccggagtacagccggtccagcctctacagcaccgacgtggcccggatg
atccaggcgccgatcttccacgtcaacggcgacgacccggagaccgtggtccgggtggcc
cggctggcctttgagtaccggcaggcgttcaacaaggacgtcgtgatcgacatggtctgc
taccgccggcgcgggcacaacgagggcgacgacccgtcgatgtccaacccgcagatgtac
aagatcatcgactcgaagcggtcggtccgcaagctctacaccgaggagctgatcggccgg
ggcgacatcaccgtcgaggacgccgaggaactgctgcgcgactaccagtcgcagctggag
cgggtcttcaaggccacccgggacgcggccaccaccccgcgtcaggtcggccggcccagc
cgccaggaggagccggagccgcaggtgcagacggccaccgacgccgccgtggtcaaggcc
atcggcgaggcgcacgtcaacctgcccgagggcttcaccccgcacaagcgcatccagcag
ttgctcgaccggcgggccaagatgtccgtcgagggcaacatcgactgggggtacggcgag
atcatcgcgttcggcgcgctgctgcacgacgggatcaccgtccggctcgccggccaggac
tcccgccggggcaccttcgtccagcggcacgcctcgatcgtcgacgccaagaccggcgag
gaccacctgccgctgaagtcgctcaccgccgacggcgagcggtcccgcttcttcgtgcac
gactcgctgctgtccgagtacgccgcgatgggcttcgagtacggctactcggtggagaac
gtcaacgcgctggtgtgctgggaggcccagttcggtgacttcgtcaacggcgcccagtcg
gtcatcgacgagttcatctcctccggcgaggtgaagtggggtcagcgttccgcggtcacc
ctgctgctgccgcacggccacgaggggcagggcccggaccacacctccggccgcccggag
cggttcctccagatgtgcgccgaggacaacatgcgggtggccatcccgaccaccccggcg
aactacttccacctgctgcgccgccaggccctgtcgcccaagcgcaagccgctggtggtg
ttcacgccgaagtcgctgctgcggcacaagctctgcgtcagcccggtggaggacttcacc
accggcacgttcgccccggtgctggccgacaccgccgcgcccgccccggagcaggtcaag
cgggtgctgctctgctcgggcaaggtctactacgacctcttccaggcccgtcaggagcgc
ggcgtcaccgacaccgcgatcatccggatcgagcagctctacccgctgccggtgcaggag
atccgggacgcgctggcggcgtacccgaacgcggaggacttcgcctgggtgcaggaggaa
ccggccaaccagggggcgtggagcttcgtcgcgctcaacctgctggagcacctgaccgac
gtccggctgcgccgcatctcccggccggccgccgccgccccggcggtcggctcggccaag
atgcacgaggtggagcagaccgcgctgatcgacgccgcgctgccccgcccctga
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