KEGG   Micromonospora sp. SH-82: WHN02_10285
Entry
WHN02_10285       CDS       T11153                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
micn  Micromonospora sp. SH-82
Pathway
micn03030  DNA replication
micn03410  Base excision repair
micn03420  Nucleotide excision repair
micn03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:micn00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    WHN02_10285 (ligA)
   03410 Base excision repair
    WHN02_10285 (ligA)
   03420 Nucleotide excision repair
    WHN02_10285 (ligA)
   03430 Mismatch repair
    WHN02_10285 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:micn03032]
    WHN02_10285 (ligA)
   03400 DNA repair and recombination proteins [BR:micn03400]
    WHN02_10285 (ligA)
Enzymes [BR:micn01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     WHN02_10285 (ligA)
DNA replication proteins [BR:micn03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     WHN02_10285 (ligA)
DNA repair and recombination proteins [BR:micn03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     WHN02_10285 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     WHN02_10285 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     WHN02_10285 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      WHN02_10285 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden OB_DNA_ligase Nlig-Ia HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT HHH BRCT_2 Auto_anti-p27
Other DBs
NCBI-ProteinID: XXG10470
LinkDB
Position
2218849..2220984
AA seq 711 aa
MPEEAIGGQVSAAQEAAAGAEPTPLARDRHATLSQELTEHQYRYYVLDAPTVSDADFDRQ
LRELEALEEQFPALRTPDSPTQRVGGTFSTDFTPVTHAERMMSLDNAFADEELAAWAERV
ERDAGGTVPYLCELKVDGLAINLTYEGGRLVRAATRGDGRTGEDVTANVRSIRDVPARLT
ASAEFAEVPEFVEVRGEIYFPVAAFADLNATLVEQGKAPFANPRNAAAGSLRQKDPRVTA
SRPLRLVVHGIGARRGFQPRTQSESYAALRAWGLPVSDRSRVVPDLTGVAEYIAHYAQHR
HDVEHEIDGVVVKVDPVSIQGRLGSTSRAPRWAIAFKYPPEEVNTKLLDIDVNVGRTGRV
TPFAVLEPVRVAGSTVALATLHNAREVERKGVLIGDTVVLRKAGDVIPEVLGPVVELRPA
DARPFVMPTTCPACGTPLAPAKEADVDIRCPNSRSCPAQLRERVFHLAGRGAFDIEVLGY
KGASALLDAQVITDEGDLFTLDAGQLARSEFFVNKDGSLGSNATKLLDNLAVARERDLWR
VLVALSIRHVGPTAAQALARHFRSMGAIEQAGEAELSSVDGVGPTIAVSIREWFAVDWHR
EVVRKWAEAGVRMVEEGGDEGPRPLEGLTVVVTGTLTGFSRDQAAEAIQTRGGKVTGSVS
KKTGFVVVGDNPGSKADKAATLKVPILDEAGFQVLLDAGPDAAREVARIEG
NT seq 2136 nt   +upstreamnt  +downstreamnt
gtgccggaggaggccatcggcgggcaggtcagtgcggcacaggaggcggctgccggcgcg
gagccgacgcccctggcccgggaccggcacgcgacgttgagccaggagctcaccgagcac
cagtaccgctactacgtgctcgacgcgccgaccgtctccgacgccgacttcgacaggcag
ctgcgcgagctggaggcgctggaggagcagttccccgcgctgcggaccccggactcgccg
acgcagcgggtcgggggcaccttctccaccgacttcaccccggtcacccacgccgagcgg
atgatgtcgctggacaacgccttcgccgacgaggagctggcggcctgggccgagcgggtc
gagcgggacgccggcgggacggtcccctacctgtgcgagctgaaggtcgacggcctggcg
atcaacctgacctacgaggggggtcggctggtccgggcggcgacccggggggacggacgc
acaggtgaggacgtgacagccaacgtccgcagcatccgcgacgtaccggcccggctcacc
gcgtcggccgagttcgcggaggtgccggagttcgtcgaggtccggggggagatctacttc
ccggtggccgccttcgccgacctgaacgccaccctggtcgagcagggcaaggcgccgttc
gccaacccccgtaacgccgccgccggcagcctgcgccagaaggacccccgggtcaccgcg
tcccggccgctgcgcctggtggtgcacggcatcggcgcccggcgcggcttccaaccccgg
acccagtccgagtcgtacgcggcgctgcgggcctggggactgcccgtcagcgaccggtcc
cgggtggtccccgacctgaccggggtggccgagtacatcgcccactacgcccaacaccgg
cacgacgtcgagcacgagatcgacggggtggtggtgaaggtcgacccggtctccatccag
ggtcggctcggctccaccagtcgggcaccacgctgggcgatcgccttcaagtaccccccg
gaggaggtcaacaccaagctcctcgacatcgacgtcaacgtcggccggaccggccgggtc
acccccttcgccgtcctggagccggtccgggtggcggggtccacggtggcgctggcgacc
ctgcacaacgcccgcgaggtggaacgcaagggcgtcctgatcggtgacacagtggtcctg
cgcaaggccggggacgtgatccccgaggtgctcggcccggtggtggagctgcgtccggcc
gacgcccgaccgttcgtcatgccgaccacctgtccggcgtgtgggaccccgctggccccg
gccaaggaggcggacgtcgacatccgctgccccaacagccggtcctgccccgcccagctg
cgtgagcgggtcttccacctcgccgggcggggtgccttcgacatcgaggtgctcggctac
aagggggcgtccgccctgctggacgcgcaggtcatcaccgacgagggggacctgttcacc
ctcgacgccgggcagctggcccgctcggagttcttcgtcaacaaggacggcagtctgggc
agcaacgccaccaagctgctggacaacctcgccgtcgccagggaacgcgacctgtggcgg
gtgctcgtcgcactctccatcagacacgtcgggccgaccgccgcacaggccctggccagg
cacttccggtcgatgggggcgatcgagcaggccggtgaggccgaactctcctccgtggac
ggcgtcggcccgaccatcgcggtgagcatcagggagtggttcgccgtcgactggcaccgc
gaggtggtccgcaagtgggccgaggcgggcgtacggatggtcgaggagggcggcgacgag
ggaccccgaccgttggaggggctgacggtggtggtcaccggcaccctgaccgggttcagc
cgggaccaggcggccgaggcgatccagacgcgcgggggcaaggtgaccggttcggtgtcc
aagaagaccggtttcgtggtggtcggcgacaaccccggctccaaggccgacaaggcggcc
accctcaaggtcccgatcctcgacgaggcgggtttccaggtcctgctcgacgccggtccc
gatgcggcccgggaggtggcccggatcgaggggtga

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