Micromonospora sp. L5: ML5_3070
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Entry
ML5_3070 CDS
T01379
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mil
Micromonospora sp. L5
Pathway
mil00020
Citrate cycle (TCA cycle)
mil00630
Glyoxylate and dicarboxylate metabolism
mil00785
Lipoic acid metabolism
mil01100
Metabolic pathways
mil01110
Biosynthesis of secondary metabolites
mil01120
Microbial metabolism in diverse environments
mil01200
Carbon metabolism
mil01210
2-Oxocarboxylic acid metabolism
Module
mil_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mil_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ML5_3070
00630 Glyoxylate and dicarboxylate metabolism
ML5_3070
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ML5_3070
Enzymes [BR:
mil01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ML5_3070
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ML5_3070
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ML5_3070
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ML5_3070
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
SHOCT-like_DUF2089-C
Motif
Other DBs
NCBI-ProteinID:
ADU08587
LinkDB
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Position
complement(3216802..3220545)
Genome browser
AA seq
1247 aa
AA seq
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MSTQQTSQENPLAGFGPNEWIVEEMYQRYLADPSSVDSAWHDFFADYRPAPGAATPRPDG
QAKPAAKPEPAEQQEAVATVTAQPAKAEPKAAPKAAPAPAKPAAKPAAKAPEPAKKSAPA
KPAAKAPTASAAGTTPLRGVAAKIVQNMDASLAVPTATSVRAVPAKLLVDNRIVINNHLT
RGRGGKVSFTHLIGYALVRAVVEHPEMNNSFAEVDGKPAMVRPEHVNLGIAIDLVKPDGS
RNLVVPSIKGCEQMDFRQFWQAYEDVVRRARRNELTMEDYSGTTISLTNPGGIGTVHSIP
RLMQGQSAIIGVGAMEYPAPYQGMSEATLAQLAVSKVITLTSTYDHRIIQGAQSGEFLKV
MHGLLLGERGFYDDIFTSLRIPYEPVRWMRDVAVDSEGQINKTARVHELIHAYRVRGHLM
ADTDPLEFKIRKHPDLDVLQHGLTLWDLDRVFPVNGFAGQQRMKLRSILGVLRDSYCRRV
GIEYMHIQDPEERRWIQERVERKYEKPSSDEQKHVLNRLNAAEAFETFLQTKYVGQKRFS
LEGGESLIPLLGEVLECSAEAGLDEVVIGMAHRGRLNVLANIVGKPYEKIFSEFEGHLDP
RSTQGSGDVKYHLGQNGKFTTPDGEHAVKVSVVANPSHLEAVDPVLEGIVRAKQDRIDLK
LEGYTVLPLAVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEYSRS
SLYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQAFNKDVVIDMVCYRRRGHNEGD
DPSMSNPEMYKIIDSKRSVRKLYTEELIGRGDITVEDAEELLRDYQGQLERVFKATRDAA
TTPRQLSRPAREEEPEPQVDTATDAAVVKAIGEAHVNLPEGFTPHKRIQQLLERRRKMSV
EGGIDWGFAEIIAFGTLLHDGVTVRLAGQDSRRGTFVQRHASVVDAKTGEDYLPLKSLTA
DGERSRFFVHDSLLSEYAAMGFEYGYSVENINALVAWEAQFGDFVNGAQSVIDEFISSGE
VKWGQRSAVTLLLPHGHEGQGPDHTSGRPERFLQLCAEDNMRVAIPTTPANYFHLLRRQA
LSPKRKPLVVFTPKSLLRHKLCVSPVEDFTTGTFQPVLADTAAPAPEQVKRVLLCSGKVY
YDLFQARQERGVTDTAILRMEQLYPLPVEEVRAALAQYPNAEDFAWVQEEPANQGAWSFV
ALNLLEHLPEVRLRRISRPAAAAPAVGSAKMHEVEQNALIEAALPRP
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcaggagaacccactggcgggtttcggcccgaacgagtgg
atcgtcgaggagatgtaccagcgctacctcgccgacccctcgagcgtcgattcggcctgg
cacgacttcttcgccgactaccggccggccccgggcgccgccacaccgcgcccggacggg
caggccaagccggccgcgaagccggagccggccgagcagcaggaggcggtggcgaccgtc
accgcgcagcccgccaaggccgagccgaaggccgcccccaaggccgcgcccgctccggcc
aagcccgccgccaagccggcggcgaaggcgcccgagccggccaagaagtccgccccggcc
aagccggccgccaaggcgccgaccgcgagcgccgcgggcaccacgccgctgcgcggcgtc
gccgccaagatcgtgcagaacatggacgcgtcgctcgccgtcccgaccgccacgagcgtg
cgcgccgtcccggccaagctgctcgtcgacaaccgcatcgtgatcaacaaccacctgacc
cgcggtcgcggtggcaaggtcagcttcacccacctgatcgggtacgcgctcgtccgcgcg
gtcgtcgagcacccggagatgaacaactccttcgccgaggtcgacggcaagccggcgatg
gtccgcccggagcacgtcaacctgggcatcgcgatcgacctggtcaagccggacggctcg
cgcaacctggtggtgccgtccatcaagggctgcgagcagatggacttccggcagttctgg
caggcgtacgaggacgtggtccggcgcgcccgccgcaacgagctgaccatggaggactac
tccggcaccacgatctcgctgaccaacccgggcggcatcggcacggtgcactcgatcccg
cgcctgatgcaggggcagagcgccatcatcggcgtcggggcgatggaatacccggccccc
taccagggcatgagcgaggccaccctggcccagctcgcggtcagcaaggtcatcacgctg
accagcacgtacgaccaccggatcatccagggcgcgcagtccggcgagttcctgaaggtc
atgcacgggctgctgctcggcgagcgcggcttctacgacgacatcttcacctcgctgcgc
atcccgtacgagccggtgcgctggatgcgcgacgtggccgtcgacagcgaaggccagatc
aacaagaccgctcgggtgcacgagctgatccacgcgtaccgggtgcgcggccacctgatg
gccgacaccgacccgctggagttcaagatccggaagcacccggacctggacgtgctccag
cacgggctcacgctctgggacctcgaccgcgtcttcccggtcaacggcttcgccggccag
cagcggatgaagctgcggtcgatcctcggcgtgctgcgcgactcgtactgccgccgggtc
ggcatcgagtacatgcacatccaggacccggaggagcggcgctggatccaggagcgggtc
gagcgcaagtacgagaagcccagctccgacgagcagaagcacgtgctgaaccggctcaac
gccgccgaggcgttcgagacgttcctccagaccaagtacgtcggccagaagcgcttctcg
ctggagggcggcgagtcgctgatcccgctgctcggcgaggtgctggagtgctccgccgag
gccgggctggacgaggtcgtcatcggcatggcccaccgcggccggctcaacgtgctggcg
aacatcgtcggcaagccgtacgagaagatcttctccgagttcgaggggcacctcgacccg
cggtccacgcagggctcgggcgacgtgaagtaccacctcggccagaacggcaagttcacc
accccggacggcgagcacgcggtcaaggtgtcggtggtggcgaacccgtcgcacctggag
gccgtggacccggtgctggagggcatcgtccgggccaagcaggaccgcatcgacctcaag
ctggagggctacaccgtgctgccgctggcggtgcacggtgacgccgccttcgccggccag
ggcgttgtggccgagacgctcaacctgtcccagctgcgcggctaccgcaccggcggcacc
gtgcacgtggtcgtcaacaaccaggtcggcttcaccaccgctccggagtacagccggtcc
agcctctacagcaccgacgtggcccggatgatccaggcgccgatcttccacgtgaacggc
gacgacccggaggccgtggtccgggtggcccggctcgcgttcgagtaccggcaggcgttc
aacaaggacgtcgtgatcgacatggtctgctaccgccggcgcgggcacaacgagggcgac
gacccgtcgatgtccaacccggagatgtacaagatcatcgactcgaagcggtccgtccgg
aagctctacaccgaggagctgatcgggcgcggcgacatcaccgtggaggacgcggaggag
ctgctgcgcgactaccaggggcagcttgagcgggtcttcaaggccacccgggacgccgcg
accaccccgcgtcagctcagccgcccggcgcgggaggaggagccggagccgcaggtcgac
accgccaccgacgccgcagtggtcaaggcgatcggcgaggcgcacgtcaacctgccggag
ggcttcaccccgcacaagcggatccagcagctgctggagcggcgccgcaagatgtccgtc
gagggcggcatcgactggggcttcgccgagatcatcgcgttcggcacgctgctgcacgac
ggggtcaccgtccggctcgccgggcaggactcgcgccgcggcacgttcgtccagcggcac
gcctcggtggtcgacgccaagaccggcgaggactacctgccgctgaagtcgctcaccgcc
gacggcgagcggtcgcgcttcttcgtccacgactcgctgctctccgagtacgcggccatg
ggcttcgagtacggctactcggtggagaacatcaacgcgctggtggcctgggaggcccag
ttcggtgacttcgtcaacggcgcccagtcggtgatcgacgagttcatctcctccggcgag
gtgaagtggggccagcgctccgcggtgaccctgctgctgccgcacggccacgagggccag
ggcccggaccacacctccggccgcccggagcggttcctccagctctgcgccgaggacaac
atgcgggtggccatcccgaccaccccggcgaactacttccacctgctgcgccgccaggcc
ctgtcgcccaagcgcaagccgctggtggtgttcacgccgaagtcgctgctgcggcacaag
ctctgcgtgtcgccggtggaggacttcaccaccgggacgttccagccggtgctggccgac
accgcggctccggcgccggagcaggtcaagcgggtgctgctctgctcgggcaaggtctac
tacgacctgttccaggcccggcaggagcggggcgtcaccgacaccgcgatcctccggatg
gagcagctctacccgctgcccgtcgaggaggtccgagccgcgctggcgcagtacccgaac
gccgaggacttcgcctgggtccaggaggagccggccaaccagggcgcctggtcgttcgtc
gcgctcaacctgctggagcacctgcccgaggtccggctgcgccgcatctcccgcccggcc
gccgccgccccggcggtcggctcggcgaagatgcacgaggtcgagcagaacgcgctgatc
gaggcggctctcccccgcccgtga
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