KEGG   Mycobacterium paraintracellulare: OCQ_22340
Entry
OCQ_22340         CDS       T01755                                 
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mir  Mycobacterium paraintracellulare
Pathway
mir00270  Cysteine and methionine metabolism
mir00450  Selenocompound metabolism
mir00670  One carbon pool by folate
mir01100  Metabolic pathways
mir01110  Biosynthesis of secondary metabolites
mir01230  Biosynthesis of amino acids
mir04980  Cobalamin transport and metabolism
mir04981  Folate transport and metabolism
Module
mir_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mir00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    OCQ_22340
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    OCQ_22340
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    OCQ_22340
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    OCQ_22340
   04980 Cobalamin transport and metabolism
    OCQ_22340
Enzymes [BR:mir01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     OCQ_22340
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: AFC53746
LinkDB
Position
2367373..2371167
AA seq 1264 aa
MHMTAVETKTSATNTSASDAFAPNIRPDCTDELTAALRQRIMVIDGAMGTAIQRDRPDEA
GYRGDRFTEWPTALQGNNDLLNLTQPQIIEGIHREYLEAGADILETNTFNANAISLSDYD
MADLAYELNYAGAALARKAADEYSTPEKPRYVAGAIGPTTRTASISPDVNDPGARNVSYD
QLVAAYLEAANGLVDGGADLLIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGTITD
ASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMSRIADTFVSCYPNAGL
PNAFGEYDETPERQAGYIADFAEAGLVNLVGGCCGTAPPHIAEIAKVVEGKPPREVPKIE
VATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQV
IDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSI
SMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPPE
DIIFDPNCFALATGIEEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVRE
AIHAVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRDRIEDVVLNRREDAAERLLEIAER
FNKSEKSEDPAAAEWRSLPVRERITHALVKGIDAHVDDDTEELRAEIAAAGGRPIEVIEG
PLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEKEKEQNGTAAAKDTNGTI
VMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPAEKILAAAREHDADIIGLSGLITP
SLDEMSNFAVEMEREGLEIPLLIGGATTSRAHTAVKISPRRSGPVVWVKDASRSVPVAAA
LLDDKQRPGLLEATEKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPAQGL
GVREFKEYDLAELREYIDWQPFFNAWEMKGRFPDILNNPATGEAARKLYDDAQEMLDTLI
KEKWLTANAVIGFFPANAVGSGIEDIEVYTDDTRTEVLTTLHHLRQQGEHREGIPNRSLS
DYIAPKDTGLADYIGAFAVTAGLGSGEKIAEFKAALDDYSAILLESLADRLAEAFAERMH
QRVRKEFWGFKPDEHLDNDALIAEKYQGIRPAPGYPACPEHTEKATLWKLMDVHERTGIE
LTESMAMWPGAAVSGWYFSHPQSQYFVVGRMAQDQVADYARRKGWTLKEGERWLSSNLAY
NPED
NT seq 3795 nt   +upstreamnt  +downstreamnt
atgcacatgacggccgttgagacgaagacttccgcgacgaacacttccgcgtcggatgcc
ttcgcgccgaacatccgccccgactgcaccgacgaactgacggcggccctgcgccagcgg
atcatggtgatcgacggcgcgatgggcacggcgatccagcgggaccggccggacgaggcc
ggctaccgcggcgatcggttcacggaatggccgaccgccctgcagggcaacaacgacctg
ctcaacctgacgcaaccgcagatcatcgagggcatccaccgcgagtacctcgaggcgggc
gccgacatcctggaaaccaacacgttcaacgcgaacgccatctcgctctccgattacgac
atggccgacctggcctacgagctcaactacgccggcgccgccctggcccgcaaggcggcc
gacgagtacagcaccccggagaagccccgctacgtggccggcgcgatcgggccgacgacg
cggaccgcgtcgatctcgccggacgtcaacgatcccggcgcccgcaacgtctcctacgac
cagctggtcgccgcctacctggaagccgccaacggcctggtcgacggcggtgcagacctg
ctcatcatcgagacgatcttcgactcgctgaacgccaaggcggcggtgttcgccgtcgag
acgctgttcgaggaccgcggacgccgctggccggtgatcatctcgggcaccatcaccgat
gcctccgggcggacgctgtccggtcaggtcaccgaagcattctggaacgcgatcaggcac
gcgaagccgatcgcggtcggcctcaactgcgccctgggcgcgccggagatgaggccctac
atcgccgagatgtcgcggatcgcggacacctttgtctcctgctatccgaacgccggcctg
cccaacgccttcggcgagtacgacgagaccccggagcgtcaggccggctacatcgccgac
ttcgccgaggcgggcctggtcaacttggtcggcgggtgctgcggaacggcgccgccgcac
atcgccgagatcgccaaggtcgtcgagggcaaaccgccgcgcgaggtgccgaagatcgag
gtggccacccgtctgtcgggcctggagccgctcaacatcaccgacgattccctgttcgtg
aacatcggtgagcgcaccaacatcaccggttccgcccggttccgcaacctgatcaaggcc
gaggactacgacaccgcgctgtcggtcgccctgcagcaggtcgaggtcggtgcgcaggtc
atcgacatcaacatggacgaaggcatgatcgacggcgtcgccgcgatggaccggttcacc
aagctgatcgcggccgagccggacatcagccgcgtcccggtgatgatcgactcctccaag
tgggaggtcatcgaggccggcctgaagaacgtgcagggcaagccgatcgtcaactcgatc
tccatgaaggagggcgaggagaaattcattcgtgaggcgcggctgtgccgcaagtacggc
gccgccgtcgtcgtgatggcgttcgacgagcagggtcaggccgacaacctggagcgccgc
aaggagatctgcgggcgcgcctaccggatcctgaccgaggaggtcggcttcccgcccgag
gacatcatcttcgacccgaactgcttcgcgctggcgaccggaatcgaggagcacgcgacg
tacgggatcgacttcatcgaggcctgcgcctggatcaaggagaaccttcccggggtgcac
atctccggcggcatctcgaacgtgtcgttctcgttccgcggcaacaacccggtccgcgag
gcgatccacgcggtgttcctgtttcacgccatcaaggccggcctggacatgggcatcgtc
aacgccggcgcgctggtgccctacgactcgatcgaccccgagctgcgcgaccgcatcgag
gacgtcgtcctgaaccgccgcgaggacgcggccgaacggctgctcgagatcgccgagcgg
ttcaacaagtcagagaaatccgaagaccccgccgcggccgaatggcgcagccttccggtc
cgcgagcggatcacccacgctttggtcaagggcatcgacgcccacgtcgacgacgacacc
gaggaattgcgggccgagatcgccgccgccgggggccgcccgatcgaggtgatcgagggc
ccgctgatggacggcatgaacgtcgtcggtgacctgttcggctcgggcaagatgtttttg
ccccaggtggtgaagtcggcccgggtgatgaagaaggccgtggcgtacctgctgccgttc
atcgagaaagagaaagaacagaacggtacggcagcggcgaaggacaccaacggcacgatc
gtgatggcgaccgtgaaaggcgacgtccacgacatcggcaagaacatcgtcggggtcgtc
ttgcagtgcaacaacttcgaagtgatcgaccttggggtgatggtgcccgccgagaagatc
ctggccgcggccagggagcacgacgccgacatcatcggactgtccggactgatcaccccg
tccctggatgagatgtccaacttcgccgtcgagatggaacgtgaaggcctcgagatcccg
ctgctcattggcggcgcgaccacctcgcgcgctcacacggccgtgaagatatcgccgcgc
cggtccggtccggtggtgtgggtcaaggacgcgtcccgctcggtgccggtcgccgcggcc
ctcctcgatgacaagcagcggccgggcctgctggaagccaccgagaaggactacgcatcg
ctgcgagagcggcacgctcagaagaacgagcgcccgatgctcacgctggagaaggcccgc
gccaaccggaccccgatcgagtgggacggctacacgccgccggtgcccgcccagggcctc
ggggtgcgggagttcaaggagtacgacctcgccgagttgcgcgagtacatcgattggcag
ccgttcttcaatgcctgggagatgaagggccgcttccccgatatcctcaacaacccggcc
accggcgaggccgcccgcaagctgtacgacgatgcgcaggagatgctcgacaccctgatc
aaggagaagtggctgaccgccaacgcggtgatcgggttcttcccggccaacgcggtcggc
tcgggtatcgaagacatcgaggtctacaccgacgacacccgcaccgaggtgctgaccacg
ctgcaccacctgcgtcagcagggggagcaccgggagggcatcccgaaccggtcgctaagc
gactacatcgcgcccaaggacaccggcctggccgactacatcggcgcgttcgccgtcacc
gccgggctcggcagcggtgaaaagatcgcggagttcaaggcggccctcgacgactacagc
gcgatcctgctggagtcgctcgccgaccggctggccgaggcgttcgccgaacggatgcac
cagcgggtccgcaaggagttctggggattcaagcccgacgagcacttggacaacgacgca
ctcatcgccgagaagtaccaggggatccgccccgccccgggctacccggcgtgcccggag
cacaccgagaaggcgacgctctggaagttgatggacgtccacgagcgcaccggaatcgag
ctcaccgagtcgatggcgatgtggcccggcgcggccgtcagcggctggtatttctcgcac
ccgcagtcgcagtacttcgtggtcggccggatggcccaggaccaggtcgccgactacgcg
aggcgcaagggctggaccctgaaggaaggtgagcgctggctcagctccaacctcgcctac
aacccggaggactga

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