KEGG   Mycolicibacter sinensis: JDM601_1775
Entry
JDM601_1775       CDS       T01512                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase MetH
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mjd  Mycolicibacter sinensis
Pathway
mjd00270  Cysteine and methionine metabolism
mjd00450  Selenocompound metabolism
mjd00670  One carbon pool by folate
mjd01100  Metabolic pathways
mjd01110  Biosynthesis of secondary metabolites
mjd01230  Biosynthesis of amino acids
mjd04980  Cobalamin transport and metabolism
mjd04981  Folate transport and metabolism
Module
mjd_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mjd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    JDM601_1775 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    JDM601_1775 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    JDM601_1775 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    JDM601_1775 (metH)
   04980 Cobalamin transport and metabolism
    JDM601_1775 (metH)
Enzymes [BR:mjd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     JDM601_1775 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: AEF35775
UniProt: F5Z1U9
LinkDB
Position
1932475..1936203
AA seq 1242 aa
MTNFEPNIQPDCTEELTAALRRRIVVIDGAMGTAIQRDRPDEAGYRGERFSEWPTPLQGN
NDLLTLTQPEIIEGIHREYLEAGADILETNTFNANAISLSDYDMADLSYELNYAGAALAR
KAADEYSTGDKPRYVAGTIGPTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVDGG
ADIILIETIFDSLNAKAAVFAVETLFEERGRRWPVIISGTITDASGRTLSGQVTEAFWNS
IRHARPIAVGLNCALGAPEMRPYIAEMARIADTHVSCYPNAGLPNAFGEYDEDPERQASY
IAEFAEAGLVNLVGGCCGTAPEHIAEIAKVVEGKPPRELPTIEVATRLAGLEPLNITDDS
LFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMD
RFTKLIASEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIVNSISMKEGEEKFIREARLCR
KYGAAVVVMAFDEQGQADNLERRKEICGRAYRVLTEQVGFPAEDIIFDPNCFALATGIEE
HATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHAVFLYHAIKAGLDM
GIVNAGALVPYDSIDSELRERIEDVVLNRRPDAAERLLEIAERFNSSGEGTRDADLAEWR
NLPARERITHALVKGIDAHVDEDTEELRAEIAAAGGRPIEVIEGPLMDGMNVVGDLFGAG
KMFLPQVVKSARVMKKAVAYLLPYIEAEKQPGEDDHTNGTIVMATVKGDVHDIGKNIVGV
VLQCNNYTVVDLGVMVPAEKILTAAREYDADMIGLSGLITPSLEEMAGFAAEMEREGLEI
PLLIGGATTSSAHTAVKIAPRRSAPVIWVKDASRSVPVVAALLDDKQRPALLESTAADYA
SLRERHAQKNERPMVPLEKARANRTPIEWDGYTPPVPVIGTGVWEFLDYDLAELREYIDW
QPFFNAWEMKGRFPDILNNPASGEAARKLYNEAQQMLDTAIEEKWLTANAVIGFFPANAV
GDDVEVYTDDTRTEVLTMFHNLRQQGAHRPGIPNRSLGDYIAPKETGLADYIGAFAVTAG
LGSGEKIAEFKEALDDYSAILLESVADRLAEAFAERMHQRVRKEFWGFQPDEALDNDALI
AEKYQGIRPAPGYPACPEHTEKATIWKLMDVQERTRIELTDSMAMWPGAAVSGLYFSHPQ
SQYFVIGRLAQDQVADYAKRKGWTLAEAERWLGSNLGYNPED
NT seq 3729 nt   +upstreamnt  +downstreamnt
gtgactaactttgagcccaacatccagcctgactgcaccgaggagctgacggctgcgctg
cgacggcggatcgtggtgatcgacggcgcgatgggcacggcgatccagcgcgaccggccg
gatgaggccggttaccgcggcgagcggttcagcgagtggcccaccccgctgcagggcaac
aacgacctgctcaccttgacgcaaccggagatcatcgagggcatccaccgcgagtatctc
gaggcgggcgccgacatcttggagaccaacaccttcaacgcgaacgcgatctcgctgtcg
gactacgacatggcggacctcagctatgagctgaactatgcgggcgccgccctggcccgc
aaggccgcagacgaatacagcaccggcgacaagccccgctacgtggccggcaccatcggg
ccgacgacgcggaccgcgtcgatctcgccggacgtcaacgaccccggcgcccgcaacgtc
tcctacgaccagttggtcgctgcctacctcgaagccgccaacggcctggtcgacggtggc
gccgacatcatcctcatcgagacgatcttcgactcgctcaacgccaaggcagcggtgttc
gccgtcgagacgttgttcgaggaacgtggacgccgctggccggtcatcatctccggcacc
atcaccgatgcgtccgggcgcaccttgtcgggtcaggtcaccgaggcgttctggaactcg
atccggcacgcgaggcccatcgcggtgggcctcaactgcgccctgggcgcgccggagatg
cggccctacatcgccgagatggcgcggatcgccgacacccacgtgtcctgctatcccaac
gccggcctgcccaacgccttcggcgagtacgacgaggacccggagcgtcaggccagctac
atcgccgagttcgccgaggccggcctggtcaacctggtcggaggttgctgcggaacggcg
cccgagcacatcgccgagatcgccaaggtcgtcgagggcaagccgccacgtgagctgccg
accatcgaggtggccacccggctcgcgggcctggaaccgctcaacatcaccgacgactcg
ctgttcgtcaacatcggcgagcgcaccaacatcaccggttcggcccggttccgcaacctg
atcaaggccgaggactacgacaccgcgctgtcggtcgcgctgcaacaggtcgaggtcggt
gcgcaggtcatcgacatcaacatggacgagggcatgatcgacggcgtcgccgcgatggac
cggttcaccaaactgatcgccagcgaaccggatatcagccgcgtcccggtgatgatcgac
tcctccaagtgggaggtcatcgaggcgggcctgaagaacgtgcagggcaagccgatcgtc
aactcgatctccatgaaggagggcgaggagaagttcatccgcgaggcacggctgtgccgc
aaatacggcgccgccgtcgtcgtgatggccttcgacgagcaggggcaggccgacaacctg
gagcgccgcaaggagatctgcgggcgcgcctaccgggtgctgaccgagcaggtcggcttc
ccggccgaggacatcatcttcgacccgaactgcttcgcgttggcgaccggcatcgaggag
cacgccacctacgggatcgacttcatcgaggcctgcgcctggatcaaggagaacctgccc
ggggtgcacatctccggcggcatctcgaacgtgtcgttctcgttccggggcaacaacccg
gtccgcgaggccatccatgcggtgttcctgtaccacgcgatcaaggccggcctggacatg
ggcatcgtgaacgccggagcgctggtgccctacgactcgatcgactccgagctgcgggag
cggatcgaggacgtcgtgctgaaccgtcgcccggatgcggccgagcggctgctggagatc
gccgaacggttcaactcctccggggaaggaacccgcgacgcggatcttgcggagtggcgc
aacctcccggcccgcgagcggatcacgcacgccctggtcaagggcatcgacgcccacgtc
gacgaggacaccgaggagctgcgggccgagatcgccgccgccggcggccggccgatcgag
gtcatcgagggcccgctgatggacggcatgaacgtcgtcggcgacctcttcggcgccggc
aagatgttcctgccccaggtcgtgaagtcggcccgggtgatgaagaaggccgtggcctac
ctgctgccctacatcgaggccgagaaacagcccggcgaagacgaccacaccaacggcacc
atcgtgatggcgacggtcaagggcgacgtccacgacatcggcaagaacatcgtcggggtc
gtgctgcagtgcaacaactacaccgtcgtcgacctcggggtgatggtgcccgccgagaag
atcctgaccgcggcccgggagtacgacgccgacatgatcggcctctccggcctgatcacc
ccgtcactggaggagatggccggcttcgccgccgagatggaacgcgaaggcctggagatc
ccgcttttgatcggcggcgcgaccacctcgagcgcccacacggccgtcaagatcgcgccg
cgtcgtagcgctccggtcatctgggtcaaggacgcgtcgcgctcggttccggtggttgcg
gcgctgctcgacgacaagcaacgcccggcgctgttggaatcgaccgcggccgactacgcg
tcgctgcgggaacggcacgcccagaagaacgagcggccgatggtgccgctggagaaggcc
cgcgccaaccggacccccatcgagtgggacggctacacgccgccggtgcccgttataggg
accggagtgtgggaatttcttgattacgacctcgccgagttgcgcgagtacatcgactgg
cagccgttcttcaacgcctgggagatgaagggccgctttcccgacatcctcaacaacccg
gcttccggcgaggccgcgcgcaagctgtacaacgaggcccagcagatgctcgacaccgcg
atcgaggagaagtggctgacggccaacgcggtgatcgggttcttcccggccaacgcggtc
ggtgacgacgtcgaggtctacaccgacgacacccgtaccgaggtgttgaccatgttccac
aacttgcgccagcagggcgcgcaccggccgggtatcccgaaccggtcgctgggcgactac
atcgcccccaaagaaacgggtctggccgactacatcggcgccttcgccgtcaccgcgggg
ctgggcagcggcgagaagatcgcggagttcaaggaggcgctcgacgactacagcgcgatc
ctgctggagtcggtcgccgaccggctggcggaggcgttcgccgaacggatgcaccagcgg
gttcgcaaggagttctggggattccagccggacgaggccttggacaatgacgccctgatc
gccgagaagtatcaggggatccgccctgccccgggctacccggcctgcccggagcacacc
gagaaggcgacgatctggaagttgatggacgtccaggagcggacccgcatcgagctgacc
gactcgatggcgatgtggcccggtgccgccgtcagcggcctgtatttctcgcacccgcag
tcgcagtatttcgtgatcggccggttggcccaggaccaggtcgccgactacgcgaagcgc
aagggctggacgctggccgaagccgagcgctggctcggctccaacctcggctacaacccg
gaggactga

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