Manis javanica (Malayan pangolin): 108387187
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Entry
108387187 CDS
T06054
Symbol
FASN
Name
(RefSeq) fatty acid synthase isoform X1
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00061
Fatty acid biosynthesis
mjv01100
Metabolic pathways
mjv01212
Fatty acid metabolism
mjv04152
AMPK signaling pathway
mjv04910
Insulin signaling pathway
mjv04936
Alcoholic liver disease
Module
mjv_M00082
Fatty acid biosynthesis, initiation
mjv_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
108387187 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
108387187 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
108387187 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
108387187 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
mjv01004
]
108387187 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mjv04147
]
108387187 (FASN)
Enzymes [BR:
mjv01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
108387187 (FASN)
Lipid biosynthesis proteins [BR:
mjv01004
]
Fatty acid synthase
Animal type
108387187 (FASN)
Exosome [BR:
mjv04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
108387187 (FASN)
Exosomal proteins of breast milk
108387187 (FASN)
Exosomal proteins of colorectal cancer cells
108387187 (FASN)
Exosomal proteins of bladder cancer cells
108387187 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
KAsynt_C_assoc
Ketoacyl-synt_C
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
PP-binding
Methyltransf_12
Methyltransf_23
adh_short
PS-DH
Methyltransf_11
Thiolase_N
Methyltransf_31
ACP_SdgA_C
Methyltransf_17
Motif
Other DBs
NCBI-GeneID:
108387187
NCBI-ProteinID:
XP_017500875
LinkDB
All DBs
Position
Unknown
AA seq
2510 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSKF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPASLRGTDTGVWVGVSGSEASEAL
SRDPETLLGYSMVGCQRAMMANRLSFCFDFKGPSIALDTACSSSLLALQNAYQAIRRGQC
SAAIVGGINLLLKPNTSVQFMKLGMLSTEGSCKSFDAGGEGYCRSEAILAVLLTRKSLAR
RVYATILNASTNTDGYKEQGVTFPSGEAQKQLLCSMYEPAGVAPESLEYIEAHGTGTKVG
DPQELNSIAQALCASRQDPLLIGSIKSNMGHPEPASGLAALAKVLLCLEHGLWAPNLHFH
SPNPKIPGLQDGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILQPNSQARLAPAAHTTL
PRLLRASGRTPEAVQALLEQGHQHSQDLAFVSLLNDIAATPTSSMPFRGFAVLGGRGSSQ
EVQQVPPGERPPLWFICSGMGTQWCRMGLSLMRLDSFHKSILRSDEIVRPLGVQVSDLLL
STDESTFDDIVHAFVSLTAIQIALIDLLTSMGLTPDGIIGHSLGEVACGYADGCLSQEEA
VLSAYWRGQCIKEANILPGAMVAVGLSWEESKRRCPPGVVPACHNSKDTVTISGPEAAVL
EFMEQLKQEGVFAKEVHTGGMAFHSYFMEPIAPSLLQALQKVIREPKPRSARWLSTSIPE
AQWQGSLARTFSAEYNVNNLVSPVLFQEALQHVPKHAVVLEIAPHALLQAVLKRGLKSSC
TIIPLMKKGHNDNLEFFLSNVGRLHLAGLNANPNGLFPPVELPVPRGTPLISPHIKWDHS
QTWDVPTAEDFPNGSSCSSATVYNIDTSPESPDHYLVDHCIDGRVIFPATGYLCLVWRTL
ARTLNLNVEQVPVVFEDVTLYQATILPKAGTVSLEVRLLEASHTFEVSENGNVIASGKVH
QWKDPNPKLFNSQDGLDPANPADPTAGFRLAQRDVYKLLRLHGYDYGPHFQGILEASLEG
STGQLLWKDNWVTFLDTMLQMSILDSEQRGLRLPTRITSIHIDPATHRQNVQALQGEAQA
DVVVDRCLSCTVAGGARISWLHTSVAPRRQQEQVAPVLEKLCFTPHMEDGCLAGSSALQE
ELQLCRGLARVLQTKVAQQGLKMVVPGLDGAQAPCEPPQQGLPRLLAVACQVQLSGNLPL
ELAHERPLLHEDPLLSGLLESPALKACVDTVLENTAGLRMRVVEVLAGDGRLYSHIPELL
NTQPLLQLDYTATDRHPEVLGAAQDKLQQHHVALGQWDPMGPAPGGLGAADLVVCNCAAT
TFGDPATVLGHMAAALKEGGFLLLHTLLGGHTLGETVAFLTCPEPQRGGRSLLSQDKWES
LFAGASLHLVALKKSFYGSALFLCRRPALQDCPIFLPVEDASFQWVDSLKGILADGTSQP
VWLTALGCATSGVVGMVNCLRKEPGGHRIRCILVSNLSGTSPIPRMDLGSPELQQVLRGD
LVMNVHRDGAWGAFRHFLLEQGLPEEQTEHAFVNILTRGDLSSIRWVCSPLCHAPPASPG
VQLCTIYYASLNFRDVMLATGKLSVDAIPGKWSAEDCMLGMEFSGRDASGKRVMGLVPAQ
GLATSVLLSQDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRLQRRETVLIHSGSGGV
GQAAIAIALSLGCRVFTTVGSAEKKAYLQARFPQLSETSFANSRDTSFEQHVLRHTAGKG
VDLVLNSLAEEKLQASLRCLAQHGRFLEIGKYDLSNNHLLGMAVFLKNVTFHGILLDMLF
NEASTSWREVAALLQGGIQDGVVQPLQCTVFPKARVEDAFRYMAQGKHVGKVVIQVREEE
QLALLQRPEPTLVTAMAKTFCPAHKSYIVAGGLGGFGLELAQWLVLRGAQKLVLTSRSGI
RTGYQAKQVREWRRQGVRVLVSTSNASSLEGARALITEATQLGPIGGVFNLAMVLRDAML
ENQTPDSFQDVSKPKYSGTLNLDRVTRESCPELDYFVAFSSVSCGRGNAGQTNYGFANST
MERICEKRRHDGLPGLAVQWGAIGDVGVLLETMGTNDIVVGGTLPQRIASCLEVLDIFLH
QPYPVLSSFVLARKKAIAHSDSRGPRDLVKSVAHILGIRNLATVSMDSSLVDLGLDSLMG
VEVRHMLEREFDLTLSTRDIRQLTLQRLQELSSKASPELTASVPREESPTQHQAQLNLRS
LLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLAARLSIPTYGLQCTQAAPLDS
IQSLAAYYIGCIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSH
TYVLAYTQSYRAKMTPGCEAEAETEAICFFVQQFTDMEHSRVLEALLPLKGLEERVAAAV
DLISHSHAGLDRGELSFAARSFYHKLRAAEQYQPQATYHGNVTLLRAKTGSSYGEDLGAD
YNLSQVCDGKVSVHVIEGDHHSLLEGLGLEAILSIIHGSLAEPRVSVREG
NT seq
7533 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgattgccggcatgtctgggaagctccccgagtcagagaatttggag
gagttctgggccaacctcatcggcggcgtggacatggtgacagatgacgacaggcgatgg
aaggctgggctctacggcctgcccaggcggtctggcaagctcaaggacctgtctaagttc
gatgcctctttcttcggggtccacccaaagcaagcgcacacgatggaccctcagctgcgc
ttgctgctggaggtcacctacgaggccatcgtggatggaggcatcaacccagcctcgctc
cgagggacggacactggcgtctgggtgggcgtgagtggctccgaggcctcagaggctctg
agccgagaccccgagacgcttctgggctacagcatggtgggctgccagcgtgccatgatg
gccaaccgcctttccttctgctttgacttcaaagggcccagcatagctctggacacagca
tgctcctccagcctgctggctctgcagaacgcctaccaggccatccgcagggggcagtgc
tccgcggccatcgtgggcggcatcaacctgctgctgaaacccaacacctccgtgcagttc
atgaagctgggcatgctcagcaccgagggctcctgcaaatccttcgacgcaggcggggaa
ggctactgccgctcggaggccatactggctgtgctgctgaccaggaagtccctggcccgg
cgggtgtacgccaccatcctgaatgccagcaccaacacagatggctacaaggagcaaggc
gtgaccttcccctccggggaggcccagaagcagctgttgtgctccatgtatgagccggcc
ggggtggcgcccgagtccctcgagtacattgaagcccacggcacaggcaccaaggtgggt
gacccccaggagctgaacagcatcgcccaagccttgtgtgccagccgccaagacccactg
ctcatcggctccatcaagtcaaacatggggcacccagagcccgcctccgggctcgcagcc
ctggccaaggtgctgctgtgcttggagcacgggctctgggcccccaacctgcacttccac
agccccaaccccaagatcccagggctgcaggatgggcggctacaggtggtagaccggccc
ctgcccgtccgagggggcaacgtgggcatcaactccttcggctttggtggctccaatgtg
catgtcatcctgcaacccaactcgcaagcacgcctggcacccgctgcacacaccaccctg
ccgcgcctgctgcgggccagcgggcgcacccctgaggctgtgcaggcgctcctggagcag
ggccaccagcatagccaggacctggcctttgtgagcttgctcaacgacattgcggccaca
cccacctcctccatgcccttccggggctttgctgtgcttgggggcaggggcagcagccag
gaggtgcagcaggtgccccccggtgagcgcccaccgctctggttcatctgctccgggatg
gggacacagtggtgcaggatggggctcagcctcatgcgcctagacagcttccacaagtcc
attctgcggtctgacgagatcgtgaggcccttgggggtgcaggtgtcagacctgctactg
agcacggatgagtccaccttcgatgacatcgtccatgcgtttgtgagcctcacagccatc
cagatcgcactcatagacctgctgacctccatgggcctgacgcccgacggcatcattggg
cactccctgggcgaggtggcttgtggctacgccgacggctgcctctctcaagaggaggcc
gtcctctcagcctattggcggggccagtgcatcaaggaggccaacatcctgcctggggcc
atggtggctgtaggcttgtcctgggaggagagcaaacggcgctgcccaccgggagtcgtt
cctgcctgccacaactccaaggacacagtgaccatctcggggcctgaggctgccgtgctg
gagttcatggagcagctcaagcaggagggcgtgtttgccaaggaggtgcacacaggaggg
atggccttccactcctacttcatggagcccatcgccccctctctgctgcaggccttgcag
aaggtgattcgggagccaaaaccccgctctgcgcgctggctcagcacctccatccccgag
gcccagtggcagggcagcctggcccgcaccttctcggccgagtacaacgtcaacaacctg
gtgagccccgtgctcttccaggaggctctgcagcacgtgcccaagcatgccgtggtgctg
gagatcgccccacacgccctgctgcaggctgtcctaaagagaggcctcaagtccagctgc
accatcatccccctgatgaagaagggccacaatgacaacctggagttcttcctcagcaat
gtgggcaggctccacctggcaggcctcaacgccaaccccaatggcctgttcccgcccgtg
gagctccctgttccccgaggaaccccgctcatctccccccacatcaagtgggaccacagc
cagacctgggacgtgcccactgccgaggacttccccaacggctccagctgttcctctgcc
accgtctataacatcgacaccagccctgagtcgccggaccactacctggtggaccactgc
atcgacggccgagtcatcttccccgccactggctacctgtgcctggtctggaggaccctg
gcacgcaccctgaacttaaacgtggagcaagtgcctgtggttttcgaggacgtgacactg
taccaggccaccatcctgcccaaggcggggaccgtgtccctggaggtgcggctcctggag
gcttcccacaccttcgaggtatctgagaacggcaacgtgatcgccagcgggaaggtacac
cagtggaaggaccccaaccccaagctcttcaatagccaggatggcctggaccctgcgaac
cctgcagacccaacagcggggttccgcctagcccagagggacgtgtacaagttgctccga
ctgcatggctacgactatggccctcacttccagggcatccttgaggccagccttgaaggc
agcacaggccagctgctgtggaaggacaactgggtgaccttcctggacaccatgctgcag
atgtccatcctggactccgagcagcgtggtctgcgcctgcccacccgcatcacctccatc
cacatcgaccccgccacccaccggcagaacgtgcaggcgctgcagggcgaggcccaagcc
gacgtggtggtggaccgctgtctgagctgcacagtggccggcggcgcccgcatctcatgg
ctccacacctcggtggccccgcggaggcagcaggaacaggtcgcccctgtcctcgagaag
ctctgcttcacgccgcacatggaggacgggtgcctggccgggagctcagccctacaggag
gagctgcagctatgcagggggctggcacgagtactgcagaccaaggtggcccagcagggg
ctgaagatggtggtgcccgggctggatggggcccaggccccctgtgagcccccgcagcag
ggcctgcctcggctgctggcagttgcctgccaggtgcagctcagtgggaacctgccgctg
gagctggcccacgagaggccccttctacatgaagaccccctgctcagtggtcttctcgag
tccccagcgctcaaggcctgtgtggacactgtcctggagaatacggccggcctgaggatg
agggtggtggaggtgctggccggcgacggccgcctgtactcgcacatcccggagctactc
aacacccagcccttgctgcagctggactacacggccactgaccgccaccctgaggtcctg
ggggctgcccaggacaagctgcagcagcatcacgtggccctgggccagtgggaccccatg
ggccctgccccaggcggcctgggcgcagctgacctggttgtgtgcaactgtgccgccacc
acctttggggacccagccacagtcctcggccacatggcagctgccctcaaggagggtggc
ttcctgctgcttcacactctgctcggaggacataccctcggggagacggtcgccttcctc
acctgcccagagccacagcggggcgggcggagcctcctgagccaggacaagtgggagagc
ctgtttgccggggcgtcactgcacctggtggccctgaagaagtctttctacgggtctgct
ctcttcctgtgccgccggccagccctgcaggactgccccatcttcctgcccgtggaggac
gccagcttccaatgggtagactcgctgaagggcatcctggccgacggcacctcccagccg
gtgtggctcacagccctgggctgtgccacctccggggtcgtgggcatggtgaactgtctc
cggaaggagcctggtgggcaccggattcggtgtatcctggtgtccaacctcagcggcaca
tccccaatccctcggatggacctgggctccccagagctgcagcaggtgctgcgtggggac
ctcgtgatgaacgtgcaccgggacggggcctggggggccttccgccactttctgctggag
cagggcctgccggaggagcaaacggagcacgccttcgtgaacatcctcaccaggggggac
ctctcctccatccgctgggtctgctcccctctgtgccacgccccacctgccagccctggc
gtccaactctgcaccatctactatgcctccctcaacttccgagacgtgatgctggccacg
ggcaagctgtctgtcgacgccatcccaggcaagtggtctgctgaggactgcatgctgggc
atggagttctccggccgagatgccagcggcaagcgcgtgatggggctggtgcccgcccag
ggtctggccacatccgtattgctgtctcaggacttcctgtgggacgttccctccagctgg
accctggaggaggcggcctccgtgcccgtcgtctacaccactgcctactactcgctggtg
gtgcgcggacgcctgcagcgcagggagacggtgctcatccactcgggctccggcggcgtg
ggccaggccgccatcgccatcgccctcagcctgggctgccgtgtcttcaccaccgtgggg
tcagctgagaagaaggcatacctccaggcccggttcccccagctcagcgagacaagcttt
gccaactcccgggacacgtccttcgagcagcatgtgctgcggcacacagcggggaagggt
gttgacctggtcctgaactccctggccgaagagaagctgcaggccagcttgcggtgcctg
gcccagcatggccgattcctggaaatcggcaaatacgacctttccaacaaccacctgctg
ggcatggctgtcttcctgaagaacgtgaccttccacgggatcctgctggacatgctcttc
aacgaggcgtccaccagctggcgggaggtggcggcactcctgcagggcggcatccaggac
ggcgtggtgcagcccctccagtgcaccgtgttccccaaggcccgcgtggaggatgccttc
cgttacatggcccaggggaagcacgtcggcaaagtggtcatccaggtgcgtgaggaagag
cagctggcactgctgcagaggcccgaacccaccctagtaacagccatggccaagaccttc
tgcccagcccacaagagctacatcgtggctgggggcctggggggctttggcctcgagctg
gcccagtggcttgtgctgcggggagcccagaagctcgtgctgacctcccgctctgggatc
cgcacaggctaccaggccaagcaggtacgggagtggaggcgccagggtgtgcgggtcctg
gtgtccaccagcaacgccagctcgctggaaggggcccgggcgctcatcaccgaggccact
cagctcgggcccatcggaggtgtcttcaacctggccatggtgctgagagatgcaatgctg
gagaaccagaccccggattccttccaggacgtcagcaagccaaagtacagcggcacgctg
aacctggacagggtgacccgggagtcgtgccctgagctggactacttcgtggccttctcc
tcggtgagctgcgggcgcggcaacgccggccagaccaactacggcttcgccaactccacc
atggagcgcatatgcgagaagcgccggcacgatggcctcccaggcctcgccgtgcagtgg
ggtgccattggtgacgtgggcgtcctcctggaaacgatgggcaccaatgacattgtcgtc
ggcgggacgctgccccagcgtatcgcctcctgcctggaggtgctcgacatcttcctgcac
cagccctaccctgtcctgagcagcttcgtgctggccaggaagaaggccatagcccacagt
gacagccgtggcccgcgggacctcgtgaagtccgtggcccatatcctcggcatccgcaac
ttggccacggtcagcatggacagctcgctggtggacctgggcctggactcgctcatgggt
gtggaggttcgccacatgctggagcgcgagttcgacctgactctgtccacgcgggacatc
cggcagctcacgctccagaggctccaagaactgtcctccaaggccagcccggagctgacg
gcctccgtgcccagggaggagagccccacccagcaccaggcccagctgaacctgcgctct
ctgctggtgaaccccgagggcccgaccttgactcggctcaattcggtgcagagctccgag
cggcccctgttcctcgtgcaccccatcgagggctccaccaccgtcttccacagcctggcc
gccaggctcagcatccccacctatggcctgcagtgcacgcaggccgcccccctggacagt
atccagagcctggccgcctactacatcgggtgcatcaggcaggtgcagcccgagggcccc
taccgcatcgccggctactcctacggggcctgtgtggcctttgagatgtgctcacagctg
caggcgcagcagagcccggcccccacgcacaacagcctcttcctgtttgacggctcccac
acctatgtgctggcctacacgcagagctaccgcgccaagatgacccctggctgtgaggcg
gaggcggagaccgaggccatctgcttcttcgtgcagcagttcacagacatggaacacagc
agggtgctggaggccctgctgcccctcaagggcctggaggagcgcgtggcagccgccgtg
gacctgatctctcacagccacgcgggcctggaccgtggtgagctcagctttgctgcacgg
tccttctaccacaagctgcgtgctgccgagcagtaccagccccaggccacctaccacggc
aacgtgacactgctgcgtgccaagacgggcagctcctacggcgaggacctgggtgctgac
tacaacctgtcccaggtgtgcgacggcaaggtgtccgtgcacgtcattgagggggaccac
cactcgctgctggagggcctaggtctggaggccatcctcagcattatccacggctccctg
gctgagcctcgcgtcagtgtgcgggagggctag
DBGET
integrated database retrieval system
