Manis javanica (Malayan pangolin): 108389977 Help Entry 108389977         CDS       T06054                                  Symbol HK2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv00010   Glycolysis / Gluconeogenesis mjv00051   Fructose and mannose metabolism mjv00052   Galactose metabolism mjv00500   Starch and sucrose metabolism mjv00520   Amino sugar and nucleotide sugar metabolism mjv00524   Neomycin, kanamycin and gentamicin biosynthesis mjv01100   Metabolic pathways mjv01200   Carbon metabolism mjv01250   Biosynthesis of nucleotide sugars mjv04066   HIF-1 signaling pathway mjv04910   Insulin signaling pathway mjv04930   Type II diabetes mellitus mjv04973   Carbohydrate digestion and absorption mjv05230   Central carbon metabolism in cancer Module mjv_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mjv_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:mjv00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     108389977 (HK2)    00051 Fructose and mannose metabolism     108389977 (HK2)    00052 Galactose metabolism     108389977 (HK2)    00500 Starch and sucrose metabolism     108389977 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     108389977 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     108389977 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     108389977 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     108389977 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     108389977 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     108389977 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     108389977 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mjv04131]     108389977 (HK2) Enzymes [BR:mjv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      108389977 (HK2) Membrane trafficking [BR:mjv04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     108389977 (HK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  108389977 NCBI-ProteinID:  XP_017504015 LinkDB All DBs Position Unknown AA seq 904 aa AA seqDB search MRLSDETLLEISKRFRKEMEKGLGATTHPTASVKMLPTFVRSTPDGTEHGEFLALDLGGT NFRVLRVRVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKL PLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGKDVVTLIRKAIQRRGDFDIDIVAVVN DTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDG VLDDFRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPEL LTTGHFETKDVSDIEGELDMCPPAAFLFPREKDGVRTAREVLVRLGMDPTQEDCVATHRI CQIVSTRSASLCAATLAAVLQRIKENKAGKERLRSTIGVDGSVYKKHPHFAKRLHKTVRR LVPDCDVRFLRSEDGSGKGAAMVTAVAHRLADQHRVRQKTLEPLKLSREQLLEVKRRMKV EMERGLSKETHATAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGV EMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDE SILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCE VGLIVGTGSNACYMEEMRNMELVDGDEGQMCVNMEWGAFGDNGCLDDLRTEFDVAVDELS LNPGKQKFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESD CLALLQVRAILHHLGLEGTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDT LKVTVGVDGTLYKLHPHFAKVMHETVKDLAPRCDVSFLESEDGSGKGAALITAVACRIRE AGQR NT seq 2715 nt NT seq  +upstreamnt  +downstreamnt atgcgtctttctgatgagacccttctggagatctctaagcggttccgcaaggagatggag aaagggcttggagccaccacccaccctactgcttctgtgaaaatgctgcccaccttcgtg aggtccactccagatgggacagaacatggagagttcttggctttggaccttggaggaacc aacttccgtgtgcttcgggtgagagtaacggacaacgggctccagaaggttgagatggag aaccagatatacgccatccctgaggacatcatgcgaggcagtggcacccagctatttgac cacattgccgaatgcctggctaacttcatggataagctgcaaatcaaagagaagaagctc cccttgggttttaccttctcattcccctgccaccagacgaaactagacgagagtttcctg gtgtcgtggaccaaggggttcaagtccagtggtgtggaaggtaaagatgtggttactctg atccgaaaagccatccagaggagaggggactttgatattgatattgtggctgtggtgaat gacaccgttgggaccatgatgacctgtggctatgatgaccagaactgcgagatcggcctc attgtgggtacgggcagcaatgcctgctacatggaggagatgcggcacatcgacatggtg gagggtgacgaggggcggatgtgtatcaacatggagtggggggcctttggtgatgacggc gtgcttgacgacttccgtactgagtttgaccaggagatcgacatgggctccctgaaccct gggaagcagctatttgagaagatgatcagtgggatgtacatgggggaattggtgaggctt atcctggtgaaaatggccaaggaggagctgcttttcggggggaagctcagcccggaactc ctcaccactggccactttgagaccaaagatgtttccgatattgaaggggaattggacatg tgcccacctgctgccttcctgtttcccagggagaaggatggtgtccggacggcccgtgag gtcctggtgaggctgggcatggacccgacacaggaggactgtgtggccactcaccggatc tgccagatcgtgtctacacgctcagccagcctgtgcgccgccacgctggcggctgtgctg cagcgcatcaaggagaacaaggccggcaaggagcggctgcgctctaccattggggttgac ggctctgtctacaagaagcaccctcatttcgccaagcgccttcacaagaccgtgcggcgc ctggtacccgactgtgatgtccgcttcctccgctccgaagatggcagtggcaagggggca gccatggtgacggcagtggcccaccggctggctgaccaacatcgagttcgccagaagacc ctggagcctctgaagctgagccgtgagcagctgctggaggtcaagaggaggatgaaagta gaaatggagcggggtctgagcaaggagactcatgccactgcccccgtcaagatgctgccc acctacgtgtgtgctacccctgatggcacagagaaaggtgacttcctggccttggacctc gggggaaccaatttccgggtcctgctggtgcgtgtgcgaaatgggaagcgacgtggcgtg gagatgcacaacaagatctactctatcccacaggaggtcatgcatggcactggggatgag ctctttgaccacattgtccagtgcatcgctgacttccttgagtacatgggcatgaagggt gtgtcactgcctctgggcttcactttctctttcccctgccagcagaacagcctggatgag agcattctcctcaagtggactaaaggcttcaaggcgtctggttgcgagggtgaggatgtg gtcaccctgctgaaggaagccatccaccggcgagaggagtttgacctggatgttgttgct gtggtgaatgacacagtcgggactatgatgacctgtggctatgaagaccctcactgtgaa gtcggtctcattgtgggcacaggcagcaatgcctgctacatggaggagatgcggaacatg gagctggtggacggcgacgaggggcagatgtgtgtcaacatggagtggggggcctttggg gacaacggatgcctagatgacttacgcacagagtttgatgtggctgtggatgagctttct ctcaaccctggcaaacagaagttcgaaaaaatgatcagtggcatgtacttgggtgagatt gtccgaaacatcctcattgattttaccaaacgtgggctgctcttccgtggccgcatctca gagcggctcaagacaaggggaatctttgaaaccaagttcctgtctcagattgagagcgac tgcctggccctgctgcaggtccgcgccattctgcaccacttggggctcgagggcacctgt gacgacagcatcattgtgaaggaggtgtgcactgtggtggcacggcgggcagcccagctt tgtggcgcaggcatggccgccgttgtggacaaaatacgagaaaaccgggggctggacact ctcaaagtgacagtgggcgtggatgggactctctacaagctacatcctcacttcgccaag gtgatgcatgagactgtaaaggacctggctccgagatgtgatgtgtccttcctggagtca gaggatggcagtgggaagggtgcagctctcatcactgctgtggcctgccgcatccgtgag gctggacagcgataa

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