Manis javanica (Malayan pangolin): 108391264
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Entry
108391264 CDS
T06054
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04120
Ubiquitin mediated proteolysis
mjv04144
Endocytosis
mjv04330
Notch signaling pathway
mjv04668
TNF signaling pathway
mjv04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
108391264 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
108391264 (ITCH)
04668 TNF signaling pathway
108391264 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
108391264 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
108391264 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mjv04131
]
108391264 (ITCH)
04121 Ubiquitin system [BR:
mjv04121
]
108391264 (ITCH)
Enzymes [BR:
mjv01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
108391264 (ITCH)
Membrane trafficking [BR:
mjv04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
108391264 (ITCH)
Ubiquitin system [BR:
mjv04121
]
Ubiquitin ligases (E3)
HECT type E3
108391264 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
108391264
NCBI-ProteinID:
XP_036868653
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPNPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAELDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNDDGSRPMDETRVNTNGS
DDPEDAGSGENRRINGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRMDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEYDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECCL
EMYFSVDKEILGEIKSHDLKPNGGDILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagataactgtcatttcagcaaagcttaaagaaaataaaaagaattggtttggaccaaat
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaagtgcaacaacaca
aacagtcctaaatggaaacagccccttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccaaacattgaaatctgatgttttgctgggaactgctgaattg
gatatctatgagacattaaagtcaaacaatatgaaacttgaggaagtagtagtgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcaatttgtcttgat
gggctacaattagagtctgaagttgttaccaatggtgaaactacctgttcagaaagtgct
tcacagaatgatgatggttccagacccatggatgaaacaagagtgaacacaaatggatca
gatgaccctgaggacgcagggtctggtgaaaataggagaatcaatgggaataattctcca
tcactctcaaatggtggtttcaaaccttctaggcctccaagaccttcacgtccacctcca
cctaccccacgtagaccagcatctgtgaatggttcaccatctgccacttctgaaagtgat
ggatctagtacaggctctctgccaccaacaaatacaaattcaaacacatctgagggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaggctcccctaccacctggttgggagcagagaatggaccaacatggacga
gtttactatgtagatcacattgaaaaaaggacaacatgggatagaccagaacctctacct
cctggctgggaacggcgagttgacaacatgggacgtatttattatgttgatcacttcaca
agaacaacaacgtggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcaacttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatatgatccccttggtcccttgcca
cctggatgggagaagagaacagacagcaatggtagagtgtattttgtcaaccacaacact
cgtattacacaatgggaagatcccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggaattccatattttgtggaccacaataga
agaaccaccacctatatagatccccgtaccggaaaatctgccctagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaagattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcaaataaatcccgcttcttatatcaatccagatcacctgaaatattttcgttttatt
ggacggtttattgccatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatcaatagat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgttgtttg
gaaatgtacttctctgttgataaggaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggcggcgatattcttgtaacagaagaaaacaaagaggaatatattagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggtttt
aatgaaattcttccccagcaatatttgcagtactttgatgcaaaggagttagaggtgctt
ttatgcggcatgcaagagattgatttgaatgactggcagagacacgccatctaccgtcac
tatactaggacaagcaaacagatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttttgcagtttgttactggaacttgtcgattgccagttggagga
tttgctgatctcatggggagcaatggaccgcagaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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