Manis javanica (Malayan pangolin): 108392617
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Entry
108392617 CDS
T06054
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04010
MAPK signaling pathway
mjv04020
Calcium signaling pathway
mjv04151
PI3K-Akt signaling pathway
mjv05200
Pathways in cancer
mjv05216
Thyroid cancer
mjv05223
Non-small cell lung cancer
mjv05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
108392617 (RET)
04020 Calcium signaling pathway
108392617 (RET)
04151 PI3K-Akt signaling pathway
108392617 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108392617 (RET)
05230 Central carbon metabolism in cancer
108392617 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
108392617 (RET)
05223 Non-small cell lung cancer
108392617 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108392617 (RET)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
108392617 (RET)
Protein kinases [BR:
mjv01001
]
Receptor tyrosine kinases (RTK)
RET family
108392617 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
Pkinase
RET_CLD3
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
108392617
NCBI-ProteinID:
XP_036858798
LinkDB
All DBs
Position
Unknown
AA seq
1113 aa
AA seq
DB search
MAKATAGAVGLRVLLLLLLGEAPLGLYFTRDAYWEKLYVGQPAGMPLLYVHALRDIPEEV
PSFRLGPHLYGSAYRTRLHENDWILIQEDTGLLYLNRSLDPNSWEKLSMRNGGYPLLTIY
LQVFLSPTSLREGECQWPGCARVYFSFINTSFPACGSLKPRELCFPETGLSFRIRENRPP
GTFYQFRLLPVHFFCPNVSVAYRLLGGESLPFRCAADSLEVSARWALDRELREKYELVAA
CTVRVGPREEEVMVPFPVTVYDEDDSAPTFLGGLDTASATVEFKRKEGTVVATIRVFDAD
VVPASGELLRRYTSTLLPGDTWALQTFRVEHSPNETLVQANDSFVRATIHDYKLVLNRSL
PISEGRALQLTVLVNDSDFQGPGEGVLLLHFNVSVLPVSLSLPSAYSFTVSRRAHRFAQI
GKVCVEHCQEFSGIHVQYKLQPSSTNCSALGMVTSAEDTMGTLFVNDTEALRRLECVQLQ
YMVVAADRPTRKQAQALLLVTVEGMYTAEEPGCPLSCAVSKRRPECEECGGLGSLTGRCE
WRQGDGKGISRNFSTCSPSIKTCPDGHCDAVESRDANVCPQDCLRGGSIIGGHEPGERRG
IKAGHGICNCFPEERKCFCEPEDSQDPLCDELCRTVIAAAVLFSFVVSMLLSTFCIHRYH
KNAHKPPIASAEMTFRRPAQAFPVSYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEFPR
KNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQ
VNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGSAGSRNSSYLDNP
EERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYE
EDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLF
NLLKTGYRMERPDNCSEEMYDLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLDLAAS
TPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPLTRAD
GTNTGCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcaacggccggcgccgtggggttgcgggtgctgctactgctgttgctcggc
gaagcaccactgggactctacttcaccagggatgcttactgggagaagctgtatgtgggc
cagccagctggcatgcccctgctctatgtgcacgcccttcgggacatccctgaggaggtg
cccagcttccgcctgggcccacacctctacggcagcgcttaccgcacacggctgcatgag
aacgactggatcctcatccaggaggacacgggccttctctaccttaaccggagcctggac
cccaactcctgggagaagctcagcatgcgcaatggcggctaccctctgctcaccatctac
ctccaggtcttcctgtcacccacgtccctgcgagagggcgagtgccagtggccaggctgt
gcccgcgtgtacttctccttcatcaacacctccttcccggcttgtggctccctcaaaccc
cgggagctctgcttccctgagacaggcctgtcctttcgcattcgggagaaccggcctcct
ggcaccttctatcaattccgcctgctgcctgtgcacttcttctgccccaacgtcagtgtg
gcctacaggctcctgggaggtgagagtctgcccttccgctgcgccgcggacagcctggag
gtgagcgcgcgctgggcgctggaccgggaactccgggagaagtatgagctggtggccgcg
tgcaccgtgcgtgtcggcccgcgcgaggaggaggtgatggtgccgttccccgtgaccgtg
tacgacgaagacgactcggcgcccactttcctcgggggcttggacaccgccagcgccact
gtggagttcaagcggaaggagggcaccgtggtggccacaatacgtgtcttcgatgcggat
gtggtgccagcatctggggaacttctcaggcggtacacaagcacactgctccctggggac
acctgggccctccaaaccttccgtgtggagcactcacccaacgagaccttagtccaggcc
aatgacagctttgtgcgggcaaccattcatgactacaagctggttctcaaccggagcctt
cccatctccgagggccgtgccctgcagctgacagtgctggtcaacgactcggacttccag
ggcccaggggagggtgtcctcctcctccatttcaatgtgtccgtgctgccagtcagcctg
agcctgcccagtgcctactcattcactgtgagcaggcgggcccaccgctttgcccagatt
gggaaagtctgtgtggagcactgccaggagttcagcggcattcacgtgcagtacaagctg
cagccttccagcaccaactgcagtgccctggggatggtcacctcagccgaggacaccatg
gggaccctgtttgtgaatgacacagaggccctgcggcggctcgagtgtgtccaactccag
tacatggtggtggctgctgaccggccgactcgcaagcaagcccaggccctgctgctggtc
actgtggaggggatgtacacagctgaggagccaggctgccccttgtcctgcgcagtcagc
aagaggcggcccgagtgtgaggagtgtggtggcctgggctccctgacgggcaggtgcgag
tggagacagggagatggcaaagggatcagcaggaacttctccacctgctctcccagcatc
aagacctgccctgatggccactgtgacgctgtggaaagccgagatgctaatgtctgcccc
caggactgcctccggggcggcagcatcattggagggcacgagccaggagaacgccggggg
attaaagctggccatgggatctgcaactgcttcccggaggagaggaagtgcttctgtgag
ccagaagacagccaggacccactgtgtgacgagctctgccgcacggtgatcgcggccgcc
gtgctcttctccttcgtggtctccatgctgctctccaccttctgcatccaccgctaccac
aagaatgcccacaagccgcccattgcctctgccgagatgaccttccgccggccagcccag
gccttcccggtcagctactcctcgtcaggcacccgccggccctcgctagactccatggag
aaccaggtgtctgtggattccttcaagatcccggaggatccaaagtgggaattccctcgt
aagaacctggttcttggaaaaactctgggagaaggtgaatttggaaaagtggtcaaggca
acggccttccggctgaaaggcaaagcagggtacaccaccgtggccgtgaagatgctgaaa
gagaacgcctccccaagcgagctgcgggaccttctgtcagagttcaacctcctgaagcag
gttaaccacccgcatgtcatcaagctttacggggcctgtagccaggatgggccgctactg
ctcattgtggagtatgccaagtatggctccctgcggggcttcctccgagagagccgcaag
gcagggcccggctatgtcggcagtgctggcagccgcaactccagctatttggacaaccct
gaggaacgggccctgaccatgggcgacctcatctcctttgcctggcaaatctcccggggg
atgcggtacctggcggagatgaagcttgtccatcgggacttggcagccagaaatgtcctg
gtggccgaggggcggaagatgaaaatttcagattttggcctatcccgagatgtttatgaa
gaggattcctatgtgaagaggagcaaggggaggattccagtcaaatggatggcaattgag
tccctcttcgaccatatttacaccacccaaagcgatgtgtggtccttcggtgtcctactg
tgggagattgtgactctgggaggtaacccctaccctgggattcctccggagcggctcttc
aaccttctgaagacaggctaccggatggagaggcccgacaactgcagcgaggaaatgtat
gatctgatgctgcagtgttggaagcaggaaccggacaagaggccagtgtttgccgacatc
agcaaagacctggagaagatgatggttaagaacagagactacttggacctggctgcgtct
acaccatctgactccctgctttatgatgatggcctctcagaggaggaaacacccctggtg
gactgtaataatgctcccctccctcgagccctcccctccacgtggattgaaaacaaactc
tatggcatgtcagacccgaactggcctgaagagagtcctgtaccactcacgagagccgat
ggcactaacactgggtgtccaagatatgcaaatgatagtgtatatgctaactggatggtt
tcaccctcagcggcacaattaatggacgcatttgatagttaa
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