Manis javanica (Malayan pangolin): 108394624
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Entry
108394624 CDS
T06054
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01522
Endocrine resistance
mjv04012
ErbB signaling pathway
mjv04062
Chemokine signaling pathway
mjv04148
Efferocytosis
mjv04151
PI3K-Akt signaling pathway
mjv04360
Axon guidance
mjv04370
VEGF signaling pathway
mjv04510
Focal adhesion
mjv04670
Leukocyte transendothelial migration
mjv04810
Regulation of actin cytoskeleton
mjv04935
Growth hormone synthesis, secretion and action
mjv05100
Bacterial invasion of epithelial cells
mjv05135
Yersinia infection
mjv05146
Amoebiasis
mjv05163
Human cytomegalovirus infection
mjv05165
Human papillomavirus infection
mjv05170
Human immunodeficiency virus 1 infection
mjv05200
Pathways in cancer
mjv05202
Transcriptional misregulation in cancer
mjv05205
Proteoglycans in cancer
mjv05208
Chemical carcinogenesis - reactive oxygen species
mjv05222
Small cell lung cancer
mjv05417
Lipid and atherosclerosis
mjv05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
108394624 (PTK2)
04370 VEGF signaling pathway
108394624 (PTK2)
04151 PI3K-Akt signaling pathway
108394624 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
108394624 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
108394624 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108394624 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
108394624 (PTK2)
04062 Chemokine signaling pathway
108394624 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
108394624 (PTK2)
09158 Development and regeneration
04360 Axon guidance
108394624 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108394624 (PTK2)
05202 Transcriptional misregulation in cancer
108394624 (PTK2)
05205 Proteoglycans in cancer
108394624 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
108394624 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
108394624 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108394624 (PTK2)
05163 Human cytomegalovirus infection
108394624 (PTK2)
05165 Human papillomavirus infection
108394624 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
108394624 (PTK2)
05100 Bacterial invasion of epithelial cells
108394624 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
108394624 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108394624 (PTK2)
05418 Fluid shear stress and atherosclerosis
108394624 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
108394624 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108394624 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
mjv01009
]
108394624 (PTK2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108394624 (PTK2)
Protein kinases [BR:
mjv01001
]
Non-receptor tyrosine kinases
FAK family
108394624 (PTK2)
Protein phosphatases and associated proteins [BR:
mjv01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
108394624 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
108394624
NCBI-ProteinID:
XP_036879169
LinkDB
All DBs
Position
Unknown
AA seq
940 aa
AA seq
DB search
MLEIADHVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSV
KAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIG
PEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLT
IAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKLTNSEKQGVRTHAVSMSGVS
HCQHKAKRARRFLPLVLCSREAPSDEISGDETDDYAEIIDEEDTYTMPSKSYGIDEARDY
EIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM
RQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA
YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESIN
FRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLM
TKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKP
SRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGIAALAGSIYPGQASLSDQTDSWN
HRPQEMSVWQSSVEDSAALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKP
DVRLSRGSVDREDGCLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPSHLSGLASLSSPS
DSYNEGVKPWRLQPQEISPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVP
MVKEVGLALRTLLATVDETIPALPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSL
QQEYKKQMLTAAHALAVDAKNLLDVIDQARLKVLGQPRPH
NT seq
2823 nt
NT seq
+upstream
nt +downstream
nt
atgttagagatagctgatcatgtggaccaggacattgccttgaaattgggttgtctggaa
atacggcgatcatactgggagatgcggggcaacgcactggaaaagaagtccaactatgaa
gtattagaaaaagatgttggtttgaagcggttttttcctcggagtttactggattctgtc
aaggccaaaacactaagaaaattgatccaacaaacgtttagacagtttgccaaccttaat
agagaagaaagtattctgaaattctttgagatcctctctccagtatacagatttgataaa
gaatgcttcaaatgtgcccttggttcaagctggatcatctctgtggagctggcaatcggc
ccagaagaagggatcagttacctcacagacaagggctgcaatcccacacatctggccgac
ttcaatcaagtgcagaccattcaatattcaaacagtgaagacaaagacagaaaagggatg
ctacagctaaaaatagcgggggcacccgagcctctgacggtgacagcgccgtccctgacc
attgccgagaacatggctgacttgatagatggatactgccggctggtgaatggagccaca
cagtctttcatcatccgaccccagaaagaaggagaacgggctttgccatcaataccaaag
ctcaccaacagcgaaaagcaaggcgtgaggacgcacgcagtctccatgtcaggagtcagt
cactgccaacataaagccaagagagctaggcgctttctccctttggtcctctgttcccgt
gaagctccttcggatgaaattagtggggacgagacagacgattatgctgagattatagat
gaagaagatacttacaccatgccctcaaaaagctatgggatagatgaagccagggattat
gagattcaaagagaaagaatagagcttggacgatgtattggagaaggccaatttggggat
gtacatcaaggcgtttatatgagcccagagaatccagctttggcagttgcaattaaaaca
tgtaaaaactgtacttcagacagcgtgagagagaaattccttcaagaagccttaacgatg
cgtcagtttgaccaccctcatatcgtgaagctgattggagtcatcacagagaaccctgtc
tggataatcatggagctgtgcacacttggagagctgaggtcatttctgcaagtgaggaaa
tacagtttggatctagcatctctgatcctatatgcctatcagcttagtacagctcttgct
tatctagagagcaaaagattcgtgcacagggacattgctgctcggaatgttctggtgtcc
tcaaatgattgtgtgaaattaggagactttggattatcccgatatatggaagacagtact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccggagtccatcaat
tttcgacgttttacctcagctagtgacgtgtggatgtttggtgtatgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaatt
gagaatggggaaagattaccaatgcctccaaattgccctcctaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaagctcag
ctcagcacaatcctggaggaagagaaggctcagcaagaagagcggatgaggatggagtcc
agaagacaggccacagtgtcctgggactccggagggtcagacgaagcaccacccaagccc
agcagacctggttatcctagtccaaggtccagcgaaggattttatcccagcccccagcac
atggtacaaaccaatcattaccaggtctctggctaccctggctcacatgggatcgcagcc
ctggctggcagcatctacccaggtcaggcatctctttcggaccaaacagattcgtggaat
cacaggccacaggagatgtcggtgtggcaatccagtgtggaggactctgcagctctggac
cttcgtggaatggggcaagtgttgccaccccacctgatggaagagcggctgatccgacag
cagcaggagatggaagaagatcagcgctggctggagaaagaggagagatttctgaaacct
gatgtgcggctctcccgagggagtgtggacagggaggatggatgtcttcagggcccgact
ggaaaccaacacatttatcagcctgtcggcaaaccagatcctgcagccccaccaaagaag
cccccgcgccccggggcccccagccacctgagtggcctcgccagtctcagcagccccagc
gacagttacaatgagggcgtcaagccatggaggcttcagccccaggaaatcagcccccct
cccactgccaacctggaccgctccaatgacagggtgtacgagaacgtgaccggcctggta
aaagctgtcatcgaaatgtccagcaagatccagccagccccgccggaggagtacgtcccc
atggtgaaggaagtcggcttggccctgaggacgttactagccactgtggacgaaaccatt
cccgccctgccagccagcactcaccgagagattgagatggcccagaagctgttgaactcc
gacctgggtgagctcatcaacaagatgaaactggcccagcagtatgtcatgaccagcctg
cagcaggagtacaagaagcagatgctgaccgccgctcacgccctggccgtggacgccaag
aacttactggacgtcatcgaccaggcaagactgaaagtgctcgggcagccgcggccgcac
tga
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