Manis javanica (Malayan pangolin): 108395733 Help Entry 108395733         CDS       T06054                                  Symbol PRKCG Name (RefSeq) protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv01521   EGFR tyrosine kinase inhibitor resistance mjv04010   MAPK signaling pathway mjv04012   ErbB signaling pathway mjv04014   Ras signaling pathway mjv04015   Rap1 signaling pathway mjv04020   Calcium signaling pathway mjv04066   HIF-1 signaling pathway mjv04070   Phosphatidylinositol signaling system mjv04071   Sphingolipid signaling pathway mjv04082   Neuroactive ligand signaling mjv04150   mTOR signaling pathway mjv04270   Vascular smooth muscle contraction mjv04310   Wnt signaling pathway mjv04370   VEGF signaling pathway mjv04510   Focal adhesion mjv04540   Gap junction mjv04613   Neutrophil extracellular trap formation mjv04650   Natural killer cell mediated cytotoxicity mjv04666   Fc gamma R-mediated phagocytosis mjv04670   Leukocyte transendothelial migration mjv04713   Circadian entrainment mjv04720   Long-term potentiation mjv04723   Retrograde endocannabinoid signaling mjv04724   Glutamatergic synapse mjv04725   Cholinergic synapse mjv04726   Serotonergic synapse mjv04727   GABAergic synapse mjv04728   Dopaminergic synapse mjv04730   Long-term depression mjv04750   Inflammatory mediator regulation of TRP channels mjv04911   Insulin secretion mjv04916   Melanogenesis mjv04918   Thyroid hormone synthesis mjv04919   Thyroid hormone signaling pathway mjv04921   Oxytocin signaling pathway mjv04925   Aldosterone synthesis and secretion mjv04928   Parathyroid hormone synthesis, secretion and action mjv04929   GnRH secretion mjv04935   Growth hormone synthesis, secretion and action mjv04960   Aldosterone-regulated sodium reabsorption mjv04961   Endocrine and other factor-regulated calcium reabsorption mjv04970   Salivary secretion mjv04971   Gastric acid secretion mjv04972   Pancreatic secretion mjv05017   Spinocerebellar ataxia mjv05022   Pathways of neurodegeneration - multiple diseases mjv05031   Amphetamine addiction mjv05032   Morphine addiction mjv05143   African trypanosomiasis mjv05146   Amoebiasis mjv05161   Hepatitis B mjv05163   Human cytomegalovirus infection mjv05170   Human immunodeficiency virus 1 infection mjv05171   Coronavirus disease - COVID-19 mjv05200   Pathways in cancer mjv05205   Proteoglycans in cancer mjv05206   MicroRNAs in cancer mjv05207   Chemical carcinogenesis - receptor activation mjv05214   Glioma mjv05223   Non-small cell lung cancer mjv05225   Hepatocellular carcinoma mjv05231   Choline metabolism in cancer mjv05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mjv00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     108395733 (PRKCG)    04012 ErbB signaling pathway     108395733 (PRKCG)    04014 Ras signaling pathway     108395733 (PRKCG)    04015 Rap1 signaling pathway     108395733 (PRKCG)    04310 Wnt signaling pathway     108395733 (PRKCG)    04370 VEGF signaling pathway     108395733 (PRKCG)    04066 HIF-1 signaling pathway     108395733 (PRKCG)    04020 Calcium signaling pathway     108395733 (PRKCG)    04070 Phosphatidylinositol signaling system     108395733 (PRKCG)    04071 Sphingolipid signaling pathway     108395733 (PRKCG)    04150 mTOR signaling pathway     108395733 (PRKCG)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     108395733 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     108395733 (PRKCG)    04540 Gap junction     108395733 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     108395733 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     108395733 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     108395733 (PRKCG)    04670 Leukocyte transendothelial migration     108395733 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     108395733 (PRKCG)    04929 GnRH secretion     108395733 (PRKCG)    04921 Oxytocin signaling pathway     108395733 (PRKCG)    04935 Growth hormone synthesis, secretion and action     108395733 (PRKCG)    04918 Thyroid hormone synthesis     108395733 (PRKCG)    04919 Thyroid hormone signaling pathway     108395733 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     108395733 (PRKCG)    04916 Melanogenesis     108395733 (PRKCG)    04925 Aldosterone synthesis and secretion     108395733 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     108395733 (PRKCG)   09154 Digestive system    04970 Salivary secretion     108395733 (PRKCG)    04971 Gastric acid secretion     108395733 (PRKCG)    04972 Pancreatic secretion     108395733 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     108395733 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     108395733 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     108395733 (PRKCG)    04727 GABAergic synapse     108395733 (PRKCG)    04725 Cholinergic synapse     108395733 (PRKCG)    04728 Dopaminergic synapse     108395733 (PRKCG)    04726 Serotonergic synapse     108395733 (PRKCG)    04720 Long-term potentiation     108395733 (PRKCG)    04730 Long-term depression     108395733 (PRKCG)    04723 Retrograde endocannabinoid signaling     108395733 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     108395733 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     108395733 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108395733 (PRKCG)    05206 MicroRNAs in cancer     108395733 (PRKCG)    05205 Proteoglycans in cancer     108395733 (PRKCG)    05207 Chemical carcinogenesis - receptor activation     108395733 (PRKCG)    05231 Choline metabolism in cancer     108395733 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     108395733 (PRKCG)    05214 Glioma     108395733 (PRKCG)    05223 Non-small cell lung cancer     108395733 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     108395733 (PRKCG)    05161 Hepatitis B     108395733 (PRKCG)    05171 Coronavirus disease - COVID-19     108395733 (PRKCG)    05163 Human cytomegalovirus infection     108395733 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     108395733 (PRKCG)    05143 African trypanosomiasis     108395733 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     108395733 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     108395733 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     108395733 (PRKCG)    05032 Morphine addiction     108395733 (PRKCG)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     108395733 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     108395733 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mjv01001]     108395733 (PRKCG) Enzymes [BR:mjv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      108395733 (PRKCG) Protein kinases [BR:mjv01001]  Serine/threonine kinases: AGC group   PKC family [OT]    108395733 (PRKCG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  108395733 NCBI-ProteinID:  XP_017513716 LinkDB All DBs Position Unknown AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTVDEIHVTVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFTLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWFKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRTGPSHSPSPSPSPSPTDSKRCFFGVSSGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKEHVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GPDGEPAIRAHGFFRWMDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPISPTPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggctggcctgggccccggtggaggcgattcagaagggggaccccgacccctgttttgc agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgcc cgcttcttcaagcagcctaccttctgcagccactgcaccgacttcatctgggggattgga aaacagggcctgcaatgtcaagtctgcagttttgtggttcatcgacgatgccacgagttt gtgaccttcgagtgtccaggtgctgggaaaggtccccagacagacgacccccggaacaag cacaagttccgcctgcacagctacagcagccccaccttctgcgaccactgcggctccctc ctttacgggctggtgcaccagggcatgaagtgctcctgctgcgagatgaacgtgcaccgg cgctgtgtgcgcagcgtgccctctctgtgtggcgtggaccacaccgagcgccgcgggcgc ttgcagctggaaatccgggcgcccaccgtggacgagattcacgttacggttggcgaggcc cgtaacctcattccaatggaccccaatggtctgtctgatccctatgtgaaactgaagctc atcccagaccctcggaacctgaccaaacagaagacccggacagtgaaagccacgctaaac cctgtgtggaatgagacctttgtgttcaccctgaagcccggggacgtggagcgccggctc agcgtggaggtgtgggactgggaccggacatcccgcaatgacttcatgggggccatgtcc ttcggggtctcggagctgctcaaggcgcctgtggacggctggttcaagttactgaaccag gaggagggtgaatattacaatgtgccagtggctgatgctgacaactgcagtctcctccaa aagtttgaggcctgtaactaccccctggaactgtatgagcgggtgcggacgggcccctct cactctcccagtccctctccgtcccccagccccaccgactccaagcgctgcttcttcggg gtgagctctgggcgtctgcacatctccgacttcagcttcctcatggtcctgggcaaaggc agctttgggaaggtcatgctggccgagcgcaggggctctgatgagctatacgccatcaag atcctgaagaaagacgtgattgtccaggacgatgatgtggactgcaccctggtggagaag cgtgtgctggcattggggggccgaggccccgggggccggcctcactttctcactcagcta cactccaccttccagaccccggaccgtctgtattttgtgatggagtacgtcaccgggggc gacttgatgtaccacattcagcagctgggcaagtttaaggagccccatgcagcgttctac gcagcggaaatagccatcggcctcttcttccttcacaatcaaggcattatctaccgggac ctgaaactggacaacgtgatgctggacgctgaagggcacatcaaaatcaccgacttcggc atgtgtaaagagcacgtcttccccgggaccacgacccgtaccttctgtgggacgccagac tacatagctcccgagatcattgcctaccagccctatgggaagtctgttgattggtggtcc tttggggttctgctgtatgagatgctggcaggacagcccccctttgatggagaggacgag gaggagctgttccaggccatcatggaacaaactgtcacctaccccaagtcgctttcccgg gaagccgtggccatctgcaaggggttcctaaccaagcaccctgccaagcgccttggctca gggccagatggggaacccgccatccgtgctcacggctttttccgttggatggactgggag cggctggaacgactggagatcgcgcctccgttcagaccccgcccgtgtggccgcagcggc gagaacttcgacaagttcttcacgcgggcggcgccagcgctgacacccccggaccgcctg gttctggccagcatcgaccaggcggacttccagggcttcacctacgtaaacccggatttc gtgcacccggacgcccgcagccccattagccccacgcccgtgcccgtcatgtaa

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