Manis javanica (Malayan pangolin): 108407415
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Entry
108407415 CDS
T06054
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04064
NF-kappa B signaling pathway
mjv04380
Osteoclast differentiation
mjv04650
Natural killer cell mediated cytotoxicity
mjv04658
Th1 and Th2 cell differentiation
mjv04659
Th17 cell differentiation
mjv04660
T cell receptor signaling pathway
mjv05135
Yersinia infection
mjv05166
Human T-cell leukemia virus 1 infection
mjv05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mjv05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
108407415 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
108407415 (LCK)
04660 T cell receptor signaling pathway
108407415 (LCK)
04658 Th1 and Th2 cell differentiation
108407415 (LCK)
04659 Th17 cell differentiation
108407415 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
108407415 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108407415 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
108407415 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
108407415 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
108407415 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108407415 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mjv03036
]
108407415 (LCK)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108407415 (LCK)
Protein kinases [BR:
mjv01001
]
Non-receptor tyrosine kinases
SRC family
108407415 (LCK)
Chromosome and associated proteins [BR:
mjv03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
108407415 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH2_1
SH3_16
Motif
Other DBs
NCBI-GeneID:
108407415
NCBI-ProteinID:
XP_036866621
LinkDB
All DBs
Position
Unknown
AA seq
509 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDSKAMLPIRNGSEVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQIGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRRDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDKGGFYISPRITFPGLHELVRHYTNAPDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTTPGVKLTINKLLDMAAQIAEGMAFIEEQNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAKEGAKFPIKWTAPEAINYGIFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt
gagaactgccattaccccatagtcccgctggatagcaaggccatgctgcccatccggaat
ggctctgaggttcgagatccactggtcacttatgagggctccaatcccccagcctcccca
ctgcaagacaacctggttattgccttgcatagctatgagccctctcacgatggagacctg
ggcttcgagaagggtgaacagctccgcatcctggaacagatcggcgagtggtggaaggca
cagtccctgaccactggtcaggaaggtttcatccctttcaacttcgtcgcgaaagccaac
agcctggagcctgaaccctggttcttcaagaacctcagccgcagggacgctgagcggcag
ctcctggcgcccgggaacacgcacggctccttcctgatccgggagagcgagagcacggcg
ggttcattttccctgtcggtccgggacttcgaccagaaccagggagaggtggtgaaacat
tacaagatccgtaacctggacaaaggcggcttctacatctccccgcgcatcacttttccc
ggcctgcacgagctggtccgccattacaccaatgctccggatgggttgtgcacgcggttg
agtcgcccctgccagacgcagaagccccagaagccatggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggccggccagttcggggaggtgtgg
atggggtactacaacgggcacacgaaggtggcagtgaagagcctgaaacagggcagcatg
tcccccgacgccttcctggcagaggccaacctcatgaagcagctgcaacaccagcggctg
gtccggctgtacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag
aacgggagcctggtggatttcctcaagactaccccaggcgtcaagctgaccatcaacaaa
ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcagaattat
atccatcgtgacctgagggctgctaacatcctagtgtctgacaccctgagctgcaagatc
gcagactttggcctagcacgcctcattgaggacaatgagtacacagccaaggagggggcc
aagtttcccattaagtggacggcaccagaagccattaactacgggatcttcaccatcaag
tcagacgtatggtcttttgggatcctgctgacagagattgtcacccacggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg
cgccctgacaactgtccagaagaactgtaccacctcatgatgctgtgctggaaggagcgc
ccagaggacaggcccacctttgactacctgcgcagcgtgctggaggactttttcacggcc
acagagggccagtaccagccccagccctga
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integrated database retrieval system
