Manis javanica (Malayan pangolin): 108409101
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Entry
108409101 CDS
T06054
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv04022
cGMP-PKG signaling pathway
mjv04024
cAMP signaling pathway
mjv04062
Chemokine signaling pathway
mjv04071
Sphingolipid signaling pathway
mjv04270
Vascular smooth muscle contraction
mjv04310
Wnt signaling pathway
mjv04360
Axon guidance
mjv04510
Focal adhesion
mjv04520
Adherens junction
mjv04530
Tight junction
mjv04611
Platelet activation
mjv04670
Leukocyte transendothelial migration
mjv04810
Regulation of actin cytoskeleton
mjv04921
Oxytocin signaling pathway
mjv05132
Salmonella infection
mjv05135
Yersinia infection
mjv05163
Human cytomegalovirus infection
mjv05200
Pathways in cancer
mjv05205
Proteoglycans in cancer
mjv05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
108409101 (ROCK2)
04071 Sphingolipid signaling pathway
108409101 (ROCK2)
04024 cAMP signaling pathway
108409101 (ROCK2)
04022 cGMP-PKG signaling pathway
108409101 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
108409101 (ROCK2)
04520 Adherens junction
108409101 (ROCK2)
04530 Tight junction
108409101 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
108409101 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108409101 (ROCK2)
04670 Leukocyte transendothelial migration
108409101 (ROCK2)
04062 Chemokine signaling pathway
108409101 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
108409101 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
108409101 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
108409101 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108409101 (ROCK2)
05205 Proteoglycans in cancer
108409101 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
108409101 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
108409101 (ROCK2)
05135 Yersinia infection
108409101 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108409101 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108409101 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mjv03036
]
108409101 (ROCK2)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
108409101 (ROCK2)
Protein kinases [BR:
mjv01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
108409101 (ROCK2)
Chromosome and associated proteins [BR:
mjv03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
108409101 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
APH
Pkinase_C
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
108409101
NCBI-ProteinID:
XP_036882445
LinkDB
All DBs
Position
Unknown
AA seq
1475 aa
AA seq
DB search
MSRPPPTGKMPGAPEAVPGDGAGSSRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WGNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLGDSPSRRDNDSMQSRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCRSVNTRLEKI
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETAKLKLEKEFINLQSILESERRDRTHGSEIINDLQGRVSGLEEDLKNGKI
LLAKVEMEKRQLQERFTDLEKEKNNMEIDMTYQLKVMQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSIFDCDLKQSQQKINELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEADDGFPVHITQSHTMESMSFTYQRSSTSLNIATKPSSSHMLLDSDSDSEEESLPNLP
ISSEPNGTESRLEGWLSLPVRNNTKKFGWVKKYVVVSSKKILFYDSEQDKEQSNPYMVLD
IDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGH
EFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDI
STAKNLLLLANSTEEQQKWVTRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQ
LAPNKPRLLDLTFKDWDWSFDDVDGGDDDDDVFDF
NT seq
4428 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccgccgacggggaaaatgcccggcgcgcccgaggccgtgccgggggac
ggggcgggctcgagccgccagaggaagctggaggcgctgatccgagaccctcgctcgccc
atcaacgtggagagcttgctggatggcttaaattccttggttcttgatttggattttcct
gctttgaggaaaaataagaatatagataatttcttaaatagatatgagaaaatagtaaaa
aaaatcagaggtctacagatgaaggcagaagactacgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtccaactggttcgacataaggcatcacagaaagtttatgcaatg
aagcttcttagtaagtttgaaatgataaaaagatcagattctgcttttttctgggaagaa
agagatattatggcctttgccaacagtccctgggtggttcagctattttgtgcctttcaa
gatgataagtatctgtacatggtaatggagtatatgcctggtggagaccttgtaaacctt
atgagtaactatgatgtacctgaaaaatgggccaaattttatactgctgaagttgttctt
gctctggatgccatacactccatgggtttaattcacagagatgtgaagcctgacaacatg
ctcttggataagcatggacatctgaaattagcagattttggcacatgtatgaagatggat
gaaacaggcatggtacattgtgatacagcagttggaacacctgattatatatcacctgag
gttctgaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgtg
ggtgttttcctttttgagatgctagtaggggatactccattttatgcagattcacttgta
ggaacatacagcaaaattatggatcacaaaaactcactatgtttccctgaagatgcagaa
atttctaaacatgcgaagaatctcatatgtgcctttttaacagatagggaggtacgactt
gggagaaatggggtagaagaaatcaaacaacatcctttctttaagaatgaccagtggaat
tggggtaacataagagagaccgcggctcctgtagtacctgaactcagcagtgacatagac
agcagcaattttgatgacattgaagatgataaaggagatgtagaaaccttcccaattcct
aaagcttttgtgggaaaccagctgccttttataggatttacctactatagagaaaatttg
ttattaggtgactctccatctcgtagagataatgattcaatgcaatcaaggaaaaatgaa
gaaagtcaagagattcagaaaaaactatacacattagaagaacacctcagcactgagata
caagccaaggaggaactagagcaaaagtgcagatctgttaatactcgcctagagaaaata
gcaaaggaactagaagaagagattaccttaaggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcacttcttcagcacaaaaatgcagaataccagcggaaagctgat
catgaagcagacaagaaacggaatttggaaaatgatgttaacagtttgaaagatcaactt
gaagatttgaaaaaaagaaaccagaactctcaaatatccactgagaaagtgaatcaactc
cagagacaactggatgaaaccaatgctctgctgcgaacagaatctgatactgcagcccgg
ttaagaaaaacccaggcagaaagttcaaaacagattcagcagctggaatcaaacaacaga
gatctgcaagataaaaattgcctgctggagactgccaagttaaaacttgaaaaggaattt
atcaatcttcagtccattctagaatctgaaagaagggaccgaacccatggatcagagata
attaatgatttacaaggtagagtatctggcctagaagaagatttaaagaatggcaaaatc
ttactagcaaaagtagagatggagaagagacagctacaggagagatttactgatttggaa
aaggaaaaaaacaacatggaaatagatatgacataccaactaaaagttatgcagcagagc
ttggaacaagaagaagctgaacacaaggctacaaaagcacggctggcagataaaaataag
atttatgaatccattgaagaagctaaatcagaagccatgaaagaaatggagaaaaagctg
ttggaggaaaggactttaaaacagaaagtggaaaacctgttgctggaagctgaaaaaaga
tgctctatatttgattgtgatctcaaacagtcccagcagaaaataaatgaactcctgaag
cagaaggatgtgctaaatgaagatgttagaaacttgacattaaaaatagagcaagaaact
cagaagcgctgccttacccaaaatgacctgaagatgcaaacacagcaagttaacacacta
aaaatgtcagaaaaacagttaaagcaagagaacaatcatctcatggaaatgaaaatgagc
ctggaaaaacagaatgctgaacttcgaaaagaacgtcaggatgcagatgggcaaatgaaa
gaactccaagatcaacttgaagcagaacagtatttctcaaccctttataaaacacaggtg
agggaacttaaagaagaatgtgaagaaaagaccaaactttgtaaagaattacagcagaag
aaacaggaattacaggatgaaagggactctttggctgctcaactagagatcaccttgacc
aaagcagattcggaacagctggctcgttcaattgctgaagaacaatattctgacttggaa
aaagagaaaatcatgaaagagctggagatcaaagagatgatggcaagacataaacaggaa
ctcactgaaaaagatgctacaattgcatctctagaagaaactaataggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaattgaaagatgcccaa
gagcagctatcaaggttgaaagatgaggagataagtgcagcagctattaaagcacaattt
gagaagcagctgttaacagagaggacactcaaaactcaagctgtgaataagttggctgag
atcatgaatcgaaaagaacctgtcaagcgtggtaatgacacagacgtgcggagaaaagag
aaagagaatagaaagctacatatggagcttaaatctgaacgtgaaaagttgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggctcaaatagctgaagagagccag
attcgaattgaactgcagatgacactggacagtaaagacagtgacattgaacagctgcgg
tcacagctccaagccttgcatatcggtctagatagttccagtataggcagtggaccaggg
gatgctgaggcagatgatgggtttccagttcatatcactcagtcacacactatggaatcc
atgtcattcacctaccaacgttcctctacttctctcaatattgccactaagccttccagt
tctcatatgcttcttgactctgattctgactcagaagaagaatctttgcctaacttacct
atttcatcggaacctaatggtacagaatcaagactagagggatggctttcattgcctgta
cgaaacaatactaagaaatttggatgggttaaaaagtatgtggttgtgagcagtaagaag
attcttttctatgacagtgaacaagataaagaacaatctaatccttacatggttttagat
atagacaagctatttcatgtccgaccagttacacagacagatgtttatagagcagatgct
aaagaaattccgaggatattccagattctgtatgccaatgaaggagaaagtaagaaggaa
caggaatttccagtggagccagtgggggaaaagtcaaattatatttgccacaagggacat
gaatttattcctactctctatcatttcccaaccaactgtgaggcttgtatgaagccattg
tggcatatgtttaaacctccccctgctttagagtgccgtcgctgccatattaaatgtcat
aaagatcatatggacaaaaaggaggagattatagcaccttgcaaagtgtattatgatatt
tcaacggcaaagaatctgttgttattagcaaattctacagaagagcagcaaaaatgggtt
actcggttggtgaaaaagataccaaaaaagcctccagctccagacccttttgcacggtca
tctcctagaacttcaatgaagatacaacaaaaccagtcaattagacggccaagtcgacag
cttgccccaaacaagccaagattacttgatttgacatttaaagactgggattggtcattt
gatgatgttgatggtggtgatgatgatgacgatgtatttgatttctga
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integrated database retrieval system
