Mycobacterium sp. KMS: Mkms_4047
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Entry
Mkms_4047 CDS
T00442
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mkm
Mycobacterium sp. KMS
Pathway
mkm00020
Citrate cycle (TCA cycle)
mkm00630
Glyoxylate and dicarboxylate metabolism
mkm00785
Lipoic acid metabolism
mkm01100
Metabolic pathways
mkm01110
Biosynthesis of secondary metabolites
mkm01120
Microbial metabolism in diverse environments
mkm01200
Carbon metabolism
mkm01210
2-Oxocarboxylic acid metabolism
Module
mkm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mkm_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mkm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Mkms_4047
00630 Glyoxylate and dicarboxylate metabolism
Mkms_4047
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mkms_4047
Enzymes [BR:
mkm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Mkms_4047
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Mkms_4047
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Mkms_4047
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Mkms_4047
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ABL93239
UniProt:
A1UK81
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All DBs
Position
4271732..4275541
Genome browser
AA seq
1269 aa
AA seq
DB search
MSSSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYNPEPTTDSSASENGQQTRTA
APKAPPEPAPAPAPKTPDSKTPDSKSQAPKQDSKPQESKPQAKAKPAESKSSTKPADAKS
EKSGKSGTNGAAKPAAQPADDSDQNQVLRGAAAAVAKNMSASLDVPTATSVRAIPAKLMI
DNRVVINNHLKRTRGGKISFTHLIGYAIVAAVKKFPNMNRHFAEVDGKPNAVTPAHTNLG
LAIDLQGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTN
PGTIGTVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRII
QGAESGDFLRTVHQLLLSDDFFDEIFRELGIPYEPVRWRTDNPDSIEDKNARVIELIAAY
RNRGHLMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREFKVNGFAGAERKKLRDVLA
VLRDAYCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQ
TKYVGQKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQI
FSEFEGNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLV
RAKQDLLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQ
IGFTTSPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDL
LCYRRRGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQ
LEQVFNEVRELEKHEIEPSESVEADQQIPAKLATAVDKSLLARIGDAHLAVPEGFTVHPR
VKPVLEKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRK
TGKEFTPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGD
FINGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTI
ALPSTPANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTY
TDGDGDRNKVTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYP
NVEEKFWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQ
EILDEAFAP
NT seq
3810 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagttcaccttcaccattcggccagaacgaatggttggtcgaggagatgtatcgc
aagttccgcgaggatccctcgtcggtagaccccagttggcacgagttcctcgtcgactac
aacccggaaccgaccaccgactccagcgcgagcgagaacggtcagcagacgcgcaccgcg
gcgcccaaggccccgccggagccggcgcccgccccggcgccgaagacgccggactcgaag
acgccggactcgaagtcgcaggcccccaagcaggattcgaagcctcaggagtccaagccg
caggcgaaagccaagcccgccgaatcgaagtcgtcgaccaagccggccgacgccaaatcc
gagaaatccggcaagtcgggcaccaacggcgccgccaaacccgccgcccagcctgccgac
gacagcgatcagaaccaggtgctgcgcggcgcggccgcggccgtcgccaagaacatgtcg
gcgtctctggacgtgcccaccgcgaccagcgtgcgcgccatcccggcgaagctgatgatc
gacaaccgcgtcgtcatcaacaaccacctcaagcgcacccgcggcggcaagatcagcttc
acccacctgatcggctatgcgatcgtggcggcggtcaagaagttcccgaacatgaaccgt
cacttcgccgaggtcgacggcaagcccaacgcggtcaccccggcgcacacgaacctgggc
ctggcgatcgacctgcagggcaaggacggtaaccggcaactggtggtcgcggccatcaag
aaggccgacaccatgcggttcggccagttcatcgccgcgtacgaggacatcgtgcggcgc
gcgcgcgacggcaagctcaccgccgaggacttctccggtgtgacgatctcgctgaccaac
ccggggaccatcggcaccgtgcactcggtgccgcggctgatgcgcggtcagggcgcgatc
atcggcgtcggcgcgatggagtacccggcggagttccagggggccagcgaggaacgcatc
gccgacctcggcatcggcaaactcatcacgctgacgtcgacctatgaccaccgcatcatc
cagggcgcggaatccggtgacttcctgcggaccgtgcaccagctgctgctgtccgacgac
ttcttcgacgagatcttccgcgaactcggcatcccgtacgagccggtgcgctggcgcacc
gacaaccccgattcgatcgaagacaagaacgcccgcgtcatcgaactgatcgcggcctac
cgcaaccgcggccacctgatggccgacatcgacccgctccggttggacagcaaccgcttc
cgcagccaccccgacctcgacgtgctcacccacgggctgacgctgtgggatctggaccgc
gagttcaaggtcaacggattcgccggtgctgagcgcaagaagctgcgcgacgtgctcgcc
gtgctgcgcgacgcctactgccgccacatcggcgtcgagtacacccacatcctcgaaccc
gaacagcagcagtggctgcaggagcgcatcgagggcaaacacgagaagcccaccgtcgcg
cagcagaagtacatcctgagccggctcaacgccgccgaggccttcgaaaccttcctgcag
accaaatacgttgggcagaaacggttctcgctcgagggcgcggagaccgtcatcccggcg
atggacgcggtgatcgaccagtgcgccgagcatgcgctcgacgaggtcgtcatcggtatg
ccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccctacagccagatc
ttcagcgagttcgagggcaacctcaacccgtcgcaggcgcacggctccggcgacgtgaag
taccacctcggctccagcggcacctacctgcagatgttcggcgacaacgacatcacggtg
tcgctgacggccaaccccagccacctcgaggccgtcgacccggtgatggagggcctggtc
cgcgccaaacaggatctgctcgacaagggcgacaccgaggacggatacaccgtcgtcccg
ctgatgctgcacggcgacgccgcattcgccggacagggtgtggtggccgagacgctgaac
ctggcgctgctgcggggctaccgcaccggcggcaccatccacctgatcgtcaacaaccag
atcggcttcaccacgtcgccggcggccgcgaagtcgtcggagtactgcaccgacgtggcg
aagatgatcggtgcgccgatcttccacgtcaacggcgacgatcccgaggccgcggtgtgg
gtgtccaggctggccgtcgacttccggcagaagttcaagaaggacgtcgtcatcgacctg
ctgtgctaccgccgccgcgggcacaacgagggtgacgacccgtcgatgacccagccgtcg
atgtacgacgtgatcgacaccaaacgcggggtccgcaagagctacaccgaagcactgatc
ggccgcggcgacatctccatgaaagaggccgaggacgccctgcgcgactaccagggtcag
ctggagcaggtcttcaacgaggtccgcgagctggagaagcacgagatcgagcccagcgaa
tcagtggaagccgaccagcagatcccggccaaactcgccaccgcggtggacaaatcgctg
ctggcccgcatcggcgacgcccacctggcggtgccggagggtttcaccgtgcacccccgc
gtcaagccggtgctcgagaagcgtcgcgagatggcctacgagggcaaggtcgactgggcg
ttcgccgaactgctggccctgggcaccatgatctccgagggcaaactggtccggctcagc
ggtcaggacacccgccgcggcacgttcacccagcggcactcggtggtgatcgaccgcaag
accggcaaggagttcacgccgctgcagctgctggcgaccgactccgacggcaacccgacc
ggcggcaagttcctggtgtacgactcgccgctgtcggagttcgccgcggtgggcttcgag
tacgggtactccgtcggcaacccggacgcaatggtgttgtgggaggcgcagttcggcgac
ttcatcaacggcgcccagtcgatcatcgacgagttcatcagttcgggtgaggccaagtgg
ggtcagctctccgacgtcgtgctgctgctgccgcacggccacgagggtcagggccccgac
cacacctcgggccgcatcgaacggttcctgcagctgtgggccgaagggtcgatgacgatc
gcgctgccgtcgaccccggcgaactatttccacctgctgcgcaggcacagcctcgacggg
atccagcggccgctgatcgtcttcacgccgaagtcgatgctgcgcaacaaggccgcggtg
tccgacatccgcgacttcaccgagcagaagttccgctcggtgctcgaggagccgacctac
accgacggcgacggcgaccgcaacaaggtcacgcggatcctgctcaccagcggcaagatc
tactacgagctggtggcgcgcaagaacaaggagagccgcgacgacgtggcgatcgtgcgc
atcgaacagctcgcaccgctgcccaaacggcggctggccgagacgctggacaagtacccg
aacgtcgaggagaagttctgggtgcaggaggagccggccaaccagggtgcatggcccacg
ttcgggctgacgttgcccgagatgctgccggaccacttcaccggcatcaagcggatctcg
cgacgcgcgatgtcggcgccgtcgtcgggttcgtcgaaggtgcacgccgtcgaacagcag
gagatcctcgacgaggccttcgccccgtag
DBGET
integrated database retrieval system
