KEGG   Mycobacterium kubicae: I2456_15250
Entry
I2456_15250       CDS       T07774                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
mku  Mycobacterium kubicae
Pathway
mku00270  Cysteine and methionine metabolism
mku00450  Selenocompound metabolism
mku00670  One carbon pool by folate
mku01100  Metabolic pathways
mku01110  Biosynthesis of secondary metabolites
mku01230  Biosynthesis of amino acids
mku04980  Cobalamin transport and metabolism
mku04981  Folate transport and metabolism
Module
mku_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:mku00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    I2456_15250 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    I2456_15250 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    I2456_15250 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    I2456_15250 (metH)
   04980 Cobalamin transport and metabolism
    I2456_15250 (metH)
Enzymes [BR:mku01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     I2456_15250 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding MOV-10_beta-barrel
Other DBs
NCBI-ProteinID: QPI35944
UniProt: A0AAX1J3A9
LinkDB
Position
complement(3243212..3246811)
AA seq 1199 aa
MTSANKPHYDTDLLDVLSQRVVVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVL
ETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADRIRDLSERGTAIARRVADELASPDRK
RYVLGSMGPGTKLPTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLG
SRRAMKQAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSE
HLRYLSRHARIPVSVMPNAGLPVLGAKGAEYPLQPDELAEALATFISEFGLSLVGGCCGT
TPAHIREVAAAVASFNDGTKQRGERQVSFEPSVSSLYTAVPFEQESSVLVIGERTNANGS
KGFREAMIAEDYQKCLDIAKDQTRDGAHMLDLCVDYVGRDGAADMKALASRLATSSTLPI
MLDSTETPVLLAGLEHLGGRCAVNSVNYEDGDGPESRFHKTMELVAEHGAAVVALTIDEE
GQARTAEKKVQIAERLIDDITGNWGVDESSILIDTLTFTIATGQEESRRDGIETIEAIRQ
LKQRHPQVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPD
EQRQVALDLIYDRRRPEDEYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIV
DGERNGLDADLDEAMTQKPPLAIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAV
AYLEPHMEKAEDDAGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATIL
EVAEDKSADVVGMSGLLVKSTVVMKENLEEMNARGVAEKFPVVLGGAALTRSYVENDLAE
VYEGEVHYARDAFEGLKLMDTIMSAKRGEGPDPDSPEAVAARKKEAERKARHERSKRIAA
QRKAAEEPVQVPERSDVAADIEVPTPPFWGSRIVKGLAMAEYTGLLDERALFLGQWGLRG
QRGGEGPSYEELVETEGRPRLRYWLDRLSTDGILAHAAVVYGYYPAVSEGDDVVVLASPE
PDAQERYRFTFPRQQRGRFLCIADFIRSRKLATERGQVDVLPFQLVTMGRPIADFANELF
AANAYRDYLEVHGIGVQLTEALAEYWHKRIREELKFSGDRAVAADDPESVEDYFKLEYRG
ARFAFGYGACPNLEDRAKMMELLDPGRIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3600 nt   +upstreamnt  +downstreamnt
gtgacttccgctaacaagccccactacgacaccgatctgctcgacgttttgtcgcagcga
gtagtggtgggcgacggcgcgatgggcacccagttgcaggccgcggacctcactctcgat
gacttccgcggcctcgagggctgcaacgagatcctcaacgaaacccgccctgacgtgctg
gaaaccatccaccgcaactatttcgaggccggcgcggacgccgtcgagaccaacacgttc
ggctgcaacctgtccaacctcggcgactacgacatcgccgaccggatcagggacctctcc
gagcgcggcaccgccatcgcgcgccgggtcgccgacgagctggccagccccgaccgtaag
cgctatgtgttgggctcgatgggtccgggcaccaagctgcccaccctcgggcacaccgag
tacgcggtgatccgcgacgcctacaccgaggccgccctcggcatgctcgacggcggcgcc
gacgccatcctcgtcgagacctgccaggacctgctacaactcaaggccgcggtcctgggc
tcgcggcgggcgatgaagcaggccggccgccacatcccggtgttcgcccacgtcaccgtg
gaaaccaccggcaccatgctgctgggcagtgaaatcggtgcggcgttgaccgccgttgag
ccgctcggcgtcgacatgatcggcctcaactgcgcgaccggccccgccgagatgagcgag
cacctgcgctacctgtctcggcacgcccgcatcccggtgtcggtgatgcccaacgccgga
ctgccggtgctgggcgccaagggcgcggagtatccgctgcagcccgacgaacttgccgag
gcgctggccaccttcatctccgagttcgggctgtcactggtcggcggctgctgtggcacc
acccccgcccacatccgcgaggtcgccgccgccgtcgcctccttcaacgacggcaccaaa
cagcgcggcgagcggcaggtcagcttcgagccgtcggtgtcctcgctgtacaccgccgtt
ccgttcgagcaggaatcttcggtgctggtcatcggcgagcgcacgaacgccaacggctcc
aagggattccgtgaggcgatgatcgccgaggactaccagaagtgcctcgacatcgccaag
gaccagacccgcgacggcgcccacatgctcgacctgtgcgtcgactacgtgggccgcgac
ggcgccgccgacatgaaagcgctggccagccggctggcgacgtcgtcgacactgccgatc
atgctggactcgaccgaaacccccgtgctgctagccggattggagcacctgggtggccgc
tgcgcggtcaactcggtgaactacgaggacggcgacggcccggaatcgcggttccacaag
accatggaactggtcgccgagcacggtgccgcggtggtcgcgctgaccatcgacgaagag
gggcaggcccgcaccgccgagaagaaggtgcagatcgccgaacggctgatcgacgacatc
accggcaactggggcgtcgacgaatcctccatcctcatcgacactttgacgttcaccatc
gccaccggccaggaagagtcacgtcgcgacggcatcgaaacgatcgaagccatccggcaa
ctcaagcagcgccatcctcaggtgcaaaccacgctcgggttgtccaacatctcgttcggc
ttgaatcccgctgcgcgccaagtgctcaactcggtgtttctgcacgaatgccaggaagcg
ggactggactccgcgatcgtgcacgcgtcgaagatcctgccgatgaaccggattcccgac
gagcagcgacaggtcgccctggatctgatctatgaccgccgccgccccgaggacgagtac
gacccgctgcaggagctcatgcggctgttcgagggcgtctcggcggcctcgtcgaaggaa
tcgcgcgccgccgaactggccaaactgccgctgttcgaacggcttgcgcaacgcattgtc
gacggcgaacgcaacggcctggacgccgacctcgacgaggcgatgacacagaagcccccg
ctggcgatcatcaacgagaacctgctggccggcatgaaaaccgttggcgaactgttcggt
tcgggtcagatgcagctgcccttcgtgttgcagtccgccgaggtgatgaaagccgcggtc
gcctacctggaaccgcacatggagaaggcggaggacgacgccggcaaggggcgcatcgtg
ctggccaccgtcaagggcgacgtccatgacatcggcaagaacctcgtcgacatcatcttg
agcaacaacggctacgaggtggtcaacatcggcatcaagcagccgatcgccaccatcctg
gaagtcgccgaagacaaaagcgccgacgtggtgggcatgtcgggtctgctggtgaaatcc
accgtggtgatgaaagaaaacctcgaggagatgaacgctcggggcgtcgccgagaagttt
ccggtcgtgctcggcggtgcggcgttgacccgcagctacgtcgagaacgacctggccgag
gtctacgagggcgaagtgcattatgcgcgcgacgctttcgagggcttgaagctgatggac
accatcatgagcgccaagcgcggtgagggtccggatcccgacagcccggaggccgtcgcc
gcccgcaagaaagaagccgaacgcaaggcgcgccacgagcggtccaaacgcattgctgcc
caacgcaaagccgccgaagagccggtccaggtgccggaacgttccgacgtcgccgccgat
atcgaggtaccgacgccgccgttctggggctcgcggatcgtcaagggtctggcgatggcc
gaatacaccggcctgctcgacgagcgcgccttgttcctggggcagtggggattacgcggg
cagcgtggcggagaggggccgtcgtacgaggagctggtggagaccgaaggccggccgcgg
ctgcggtactggctggaccggttgtccaccgacggcatcctggcgcacgcggcagtggtg
tacggctactacccggcggtgtccgagggcgacgacgtggtggtcctggccagccccgaa
cccgacgcgcaggagcgctaccggttcactttcccgcgccagcagcgcggccggttcttg
tgcatcgccgacttcattcggtcacgcaagctggcgaccgaacgcgggcaggtcgacgtg
ctgcccttccagttggtgacgatgggccggcccatcgccgacttcgccaacgagttgttc
gcggcgaacgcataccgcgattacctcgaagtgcacggcatcggcgtgcagctgaccgaa
gcgctggccgagtactggcacaaacgcatccgcgaagagctcaagttctccggcgatcgg
gcggtggccgccgacgacccggaatccgtcgaagactacttcaagctggagtaccgcggt
gcccgcttcgccttcggttacggcgcctgccccaacctggaggaccgggcgaagatgatg
gagctgctcgaccccggccgcatcggcgtgaccctgtccgaggaactgcagttgcatccc
gagcaatccaccgacgcgttcgtgctgcaccaccccgaggccaagtacttcaacgtgtag

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