Mycobacterium kubicae: I2456_16035
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Entry
I2456_16035 CDS
T07774
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mku
Mycobacterium kubicae
Pathway
mku00010
Glycolysis / Gluconeogenesis
mku00020
Citrate cycle (TCA cycle)
mku00620
Pyruvate metabolism
mku00785
Lipoic acid metabolism
mku01100
Metabolic pathways
mku01110
Biosynthesis of secondary metabolites
mku01120
Microbial metabolism in diverse environments
mku01200
Carbon metabolism
mku01210
2-Oxocarboxylic acid metabolism
Module
mku_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mku00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
I2456_16035 (aceE)
00020 Citrate cycle (TCA cycle)
I2456_16035 (aceE)
00620 Pyruvate metabolism
I2456_16035 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I2456_16035 (aceE)
Enzymes [BR:
mku01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
I2456_16035 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QPI36079
UniProt:
A0AAX1J3P9
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All DBs
Position
3401001..3403793
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AA seq
930 aa
AA seq
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MTTEFARNDLAKSSSNASEPDRVRVIREGVASYLPDIDPEETSEWLESFDQLLARSGPAR
ARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIM
VHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAY
LEGRLSADLLDGFRQEHSHPGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHY
LHDRGIKDTSDQHVWCFLGDGEMDEPESRGLLHIGALEGLDNLTFVINCNLQRLDGPVRG
NGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNSTPDGDYQTYKANDG
AYVRDHFFGRDPRTKALVEHMSDQEIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKT
IKGYSLGAHFQGRNATHQMKKLALEDLKAFRDSMRIPVSDAQLEEDPYLPPYYHPGADAP
EIRYMLDRRRTLGGFVPERRTKSKALKLPERKIYAAMKKGSGQQEVATTMATVRTFKEVL
RDKEVGPRIVPIIPDEARTFGMDSWFPSLKIYNRYGQLYTAVDAELMLAYKESEVGQILH
EGINEAGSVGSFIAAGTSYATHDEPMIPIYIFYSMFGFQRTGDDLWAAADQMTRGFLLGA
TAGRTTLTGEGLQHADGHSLLLAATNPAVIAYDPAYAFEIAYIIESGLARMYGENPENVY
FYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAVTEERGSRAQILASGVSMPAALKASQL
LAEDWDVAADVWSVTSWSELNRDGVAVETHRLRHPDEPARDAYVTQVLADTAGPVIAVSD
WMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALARDQEID
ASVPIKAARQYKIDDVQAARGQDEDAGSAT
NT seq
2793 nt
NT seq
+upstream
nt +downstream
nt
ttgacgaccgagttcgcgcgcaacgatctggcgaaatcatcaagcaacgcaagcgaaccc
gaccgagttcgggtgattcgtgaaggcgtcgcgtcgtatctgcccgacatcgacccggag
gaaacttcggagtggttggagtccttcgaccaactcctggcccgttccgggccggcgcgc
gcgcgatatctgatgttgcggttgctggaacgagccggcgaacaacgggtcgccatcccg
gcgttgacctccactgactacgtcaacaccattcccaccgagctggagccgtggtttccc
ggtgacgaggacgtggaacgccgctaccgcgcctggatcaggtggaacgcggccatcatg
gtgcaccgcgcgcagcggcccggcgtcggtgtcggcggccacatctcgacctacgcgtcg
tcggcggccctctacgaggtcggcttcaaccacttcttccgcggcaagtcccatcccggc
ggcggcgaccaggtgttcattcagggccacgcctcccccggcatctacgcgcgggcctac
ctcgaaggccggctcagcgccgatctgctggacggcttccgccaagagcacagccacccc
ggcggcgggttgccgtcctacccacatccgcggctgatgcccgacttctgggaattcccc
accgtgtcgatggggctgggcccgctgaacgccatctaccaagcccggttcaaccattac
ctgcacgaccggggcatcaaagacacctccgaccagcacgtgtggtgcttcctcggcgac
ggcgagatggacgagccggaaagccgcggcttgctgcacatcggcgcgctggagggcttg
gacaacctgacgttcgtcatcaactgcaacctgcagcgcctggacggcccggtgcgcggc
aacggcaagatcatccaggaactcgagtcgttcttccgcggcgccggctggaacgtcatc
aaggtggtctggggccgggaatgggatgcgctgctgcacgccgaccgcgacggcgccctg
gtgaacctgatgaactccaccccggacggtgactaccagacctacaaggccaacgacggc
gcgtatgtgcgcgaccacttcttcggccgggacccgcgcaccaaggcgctggtcgagcac
atgagcgaccaggaaatctggaacctcaaacgtggcgggcatgactaccgcaaggtttac
gccgcctaccgcgccgccgtcgaccacaagggacagccgacggtgatcctggccaagacc
atcaagggctactcactgggcgcccacttccagggccgcaacgccactcaccagatgaaa
aagcttgcgctggaagacctcaaagctttccgcgactccatgcgcatcccggtcagcgac
gcccagctggaggaagacccctatctgccgccgtattaccacccgggcgccgacgccccg
gagatccggtacatgctcgaccggcggcgcacgctgggcggcttcgttcccgaacgcagg
accaagtccaaggcactcaaattgccggaacgcaagatctacgcggcgatgaagaagggc
tccggacagcaggaagtcgccaccaccatggcgaccgtgcgcaccttcaaggaagtgttg
cgggacaaggaggttgggccgcgcatcgtgcccatcatccccgacgaggcgcgcacgttc
ggcatggactcctggttcccgtcgctgaagatctacaaccgctacggccagctctacacc
gccgtcgacgccgaattgatgttggcgtacaaggaaagtgaagtcggccagatcctgcac
gaaggcatcaacgaagcgggttcggtgggctcgttcatcgccgccggcacttcgtatgcg
acgcacgacgagccgatgattccgatctacatcttctattcgatgttcggattccagcgc
accggtgacgacctgtgggccgctgccgaccagatgacccgcgggtttctgctcggcgcc
accgccgggcgcaccacgctgaccggcgagggcctgcagcatgccgacggccattcgctg
ttgttggcggcgaccaacccggcagtgatcgcctacgacccggcgtacgccttcgagatc
gcctacatcatcgaaagcggcctggcccgcatgtacggcgagaaccccgaaaacgtgtac
ttctacatcaccgtctacaacgagccgtacgtgcagccgccggagccggagaacttcgac
cccgagggtgtgctgcgcggcatctaccgctaccacgcagtgaccgaggaacgcggcagc
agggcgcagatcctggccagcggggtgtcgatgcccgcggcgctcaaggcctcccagctg
ttggccgaggactgggatgtggccgccgacgtgtggtcggtgaccagctggagcgaactc
aaccgcgacggggtggccgtcgaaacgcatcggctgcgccatcccgacgagcccgcccgc
gacgcgtacgtcacgcaggtgctcgccgacaccgccgggccggtgatcgccgtgtcggac
tggatgcgcgccgttcccgagcagatccggccgtgggtgcccggcacgtatctgaccttg
ggcaccgacgggttcggcttctccgacacccgcccggcggcccgccgctacttcaacacc
gacgccgagtcacaagtcgtggccgtgctcgaggccctggcccgcgaccaggagatcgac
gcgtcggtgccgatcaaggcggcccgtcagtacaagatcgacgacgtccaggccgcgcgg
ggtcaagacgaggacgccggtagcgcgacctga
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