Mycobacterium kubicae: I2456_19790
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Entry
I2456_19790 CDS
T07774
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mku
Mycobacterium kubicae
Pathway
mku00020
Citrate cycle (TCA cycle)
mku00630
Glyoxylate and dicarboxylate metabolism
mku00785
Lipoic acid metabolism
mku01100
Metabolic pathways
mku01110
Biosynthesis of secondary metabolites
mku01120
Microbial metabolism in diverse environments
mku01200
Carbon metabolism
mku01210
2-Oxocarboxylic acid metabolism
Module
mku_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mku_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mku00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
I2456_19790
00630 Glyoxylate and dicarboxylate metabolism
I2456_19790
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I2456_19790
Enzymes [BR:
mku01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
I2456_19790
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
I2456_19790
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
I2456_19790
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
I2456_19790
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
DUF5724
Motif
Other DBs
NCBI-ProteinID:
QPI36690
UniProt:
A0AAX1J873
LinkDB
All DBs
Position
4236064..4239816
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AA seq
1250 aa
AA seq
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MANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPASEPATAPAAKAAPKP
APAASGDGSAQPATKPAAPPAQIPAAKPAAKAEPAKAAAANGSAAAAPKAPTPPPAEGDD
VQVLRGAAAAVVKNMSASLDVPTATSVRAIPAKLLIDNRIVINNQLKRNRGGKISFTHLL
GYALVQAVKKFPNMNRHYAEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCET
MRFAEFVSAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVG
AMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTVHEMLLADEFWDE
IFRELSIPYLPVRWSTDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDGTRFRSHP
DLEVLTHGLTLWDLDRVFKVSGFAGAEYKKLRDVLGLLRDAYCRHIGVEYTHILEPEQQQ
WLQQRIETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAA
IDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLG
ATGVYLQMFGDNDIKVSLTANPSHLEAVDPVLEGLVRAKQDLLELADSEGDGDDERPFSV
VPMMLHGDAAFAGQGVVAETLNLALLPGYRVGGTIHLIVNNQIGFTTAPEYSRSSEYCTD
VAKMVGAPIFHVNGDDPEACEWVARLAVDFRQKFKKDVIIDMLCYRRRGHNEGDDPSMTN
PAMYDVVDVKRGVRKSYTEALIGRGDISIKEAEDALRDYQGQLERVFNEVRDLEKHGVQP
SESVEADQIVPAGLATAVDKQLLARIGDAFLSLPEGFTAHPRVQPVLEKRREMAYEGKID
WAFAELLALGSLVAEGKLVRLSGQDTRRGTFSQRHSVIIDRSTGQEFTPLQLLATNKDGS
PTGGRFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEA
KWGQLSSVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTISMPSTPSNYFHLLRRHAL
DGVQRPLIVFTPKSMLRNKAAVSDIRDFTELKFRSVLEEPTYEDGDGDRSNVTRILLTAG
KIYYELAARKAKEKRNDIAIVRIEQLAPLPRRRLQDTLDRYENAKQFFWVQEEPANQGAW
PRFGLELPELLPDKLSGIKRISRRAMSAPSSGSSKVHAVEQQEILDTAFA
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
gtggccaacataagttcaccattcgggcaaaacgaatggctggtcgaggagatgtatcgc
aagttccgcgacgacccctcgtcggtcgaccccagctggcacgagttcctggttgactac
aaccccgagccggcctccgagcccgccacagcaccggccgccaaggcggcccccaagccg
gccccagcggccagtggcgacgggtccgcgcagcccgcgaccaagccggccgcgccgccc
gcccagatacccgccgccaagccggccgcgaaggccgagcccgccaaggccgccgccgcc
aatggatcggccgccgcggccccgaaggccccgactcccccgccggccgagggagacgac
gtgcaggtgctgcgcggcgccgccgccgcggtcgtcaagaacatgtccgcgtcgctggat
gtgccgacggccaccagcgtgcgagccatcccggccaagctgctgatcgacaaccggatc
gtcatcaacaaccagctcaagcgcaaccgcggcggcaagatctccttcacccacttgctc
ggctatgcgctggtgcaggcggtcaagaagttcccgaacatgaaccgccactacgccgag
gtggacggcaagcccaccgcggtcaccccagcccacaccaacctgggcctggccatcgac
ctgcagggcaaagacggcaagcggtccctggtggtggccggcatcaagcgctgcgaaacc
atgcggttcgccgaattcgtttcagcctacgaagacatcgtccgccgggcgcgcgacgga
aagctgaccgccgaggacttctccggcgtcacgatctcgctgaccaaccccggcaccatc
ggcaccgtgcactcggtgccgcggctgatggccggccagggcgccatcatcggcgtcggc
gccatggaataccccgccgaattccagggcgccagcgaagagcgcatcgccgagctgggc
atcggcaaattgatcaccctgacatccacatatgaccaccgcatcattcagggcgcggaa
tccggtgacttcctgcgcaccgtccacgagatgctgctggccgacgagttctgggacgag
atcttccgcgagctgagcatcccgtacctgccggtgcgctggagcaccgacaacccggac
tcgatcgtcgacaagaacgcccgggtcatggagttgatcgcggcctaccgcaaccgcggt
cacctgatggccgacatcgacccgctgcgtctggacggcacccggttccgcagccacccg
gacctcgaggtgctcacccacgggctcacgctgtgggacttggaccgggtgttcaaggtc
agcggcttcgccggtgcggagtacaagaagttgcgcgacgtgctgggtttgctgcgcgac
gcctactgccgccacatcggggtggagtacacccacatcctcgagcccgaacagcagcag
tggctgcagcagcggattgagaccaagcacgtcaaaccgactgtggcccaacagaagtac
atcctgagcaagctcaacgccgccgaggcgttcgagacgttcctgcagacgaaatacgtt
gggcagaaacgcttttcactggaaggtgcggagagcgtcatcccgatgatggacgccgcg
atcgaccagtgcgccgaacacggcctggacgaagtggtgatcggcatgccgcaccgcggc
cggctcaacgtgctggccaacatcgtcggcaagccctactcgcagatcttcagcgagttc
gagggcaacctgaacccgtcgcaggcgcacggctccggcgacgtcaaataccacctgggc
gccaccggggtgtacctacagatgttcggcgacaacgacatcaaggtgtcgctgacggcc
aacccgtcgcacctggaagcggtcgacccggtgctcgaaggcctggtccgcgccaagcag
gacctgttggaactggccgacagcgagggcgacggcgacgacgaacggcccttctcggtg
gtgccgatgatgctgcacggtgacgccgcgttcgccgggcagggtgtggtggccgagacg
ctgaacctggcgctgctgcccggttaccgcgtcggcggcaccatccacctcatcgtcaac
aaccagatcggcttcaccaccgccccggaatactcgcgatccagcgaatactgcaccgac
gtggccaaaatggtcggcgcgcccatcttccacgtcaacggcgacgacccggaagcctgc
gagtgggtggcgcggctggccgtggacttccggcagaagttcaagaaggacgtcatcatc
gacatgctgtgctaccggcgccgcggtcacaacgaaggcgacgacccgtcgatgaccaac
cccgccatgtacgacgtcgtcgacgtcaagcgcggcgtgcgcaagagctacaccgaagcc
ctgatcggtcgtggcgacatctcgatcaaggaagccgaagacgcgctgcgcgactaccag
ggccagctggagcgggtgttcaacgaggtccgcgacctggaaaaacacggtgtgcagccc
agcgaatcggtggaggccgaccagatcgttcccgccgggctggccaccgcggtcgacaaa
caactgctcgcccgcatcggcgatgcgttcctgtccctccccgaaggcttcaccgcgcac
ccgcgcgtccagccggtgctggagaagcgccgcgagatggcctacgagggcaagatcgac
tgggcgttcgccgagctgctggcgctgggctcgctggtcgccgagggcaaactggtgcgg
ctatcgggtcaagacacccgccgcggcaccttctcgcaacggcattcggtgatcatcgac
cgcagcaccggccaggaattcaccccgctgcagctgctggcgaccaacaaggacggcagc
ccgaccggcggccggttcctggtctacgactcaccgctgtcggagtacgccgccgtcggt
ttcgagtacggctacaccgtgggcaacccggacgcgttggtgctgtgggaggcgcagttc
ggtgacttcgtcaacggcgcgcagtcgatcatcgacgaattcatcagctccggtgaggcc
aagtggggccagttgtcctcggtggtgttgttgttgccgcacgggcatgaaggccagggc
cccgaccacacgtcgggccgcatcgagcggttcctgcagctgtgggccgaaggatcgatg
acgatctcgatgccgtcgaccccctcgaactacttccacctgttgcgccgccacgccctc
gacggcgtgcagcgcccgctgatcgtgttcaccccgaagtcgatgctgcgcaacaaggcc
gcggtcagcgacatcagggacttcaccgagctgaagttccggtcggtgctggaggagccg
acgtatgaggacggcgacggagaccgcagcaacgtgactcggattctgctgaccgccggc
aagatctactacgagctggcggcccgcaaagccaaggagaagcgcaacgacatcgccatc
gtgcgcatcgagcagctggctccgctgccccggcgtcggctccaggacaccctggaccga
tacgagaacgccaagcagtttttctgggtgcaggaagagccggccaaccagggggcatgg
ccgcggttcggcctggagctgcccgagctgctgcccgacaagctgagcgggatcaagcgg
atctcgcggcgggcgatgtctgcgccgtcgtcgggatcgtcgaaggtgcacgccgtcgag
cagcaggagatcctcgacacggctttcgcctag
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