Macrotis lagotis (bilby): 141496820 Help Entry 141496820         CDS       T11097                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism mlao  Macrotis lagotis (bilby) Pathway mlao00230   Purine metabolism mlao01100   Metabolic pathways mlao01522   Endocrine resistance mlao04015   Rap1 signaling pathway mlao04020   Calcium signaling pathway mlao04022   cGMP-PKG signaling pathway mlao04024   cAMP signaling pathway mlao04062   Chemokine signaling pathway mlao04072   Phospholipase D signaling pathway mlao04081   Hormone signaling mlao04082   Neuroactive ligand signaling mlao04114   Oocyte meiosis mlao04211   Longevity regulating pathway mlao04213   Longevity regulating pathway - multiple species mlao04261   Adrenergic signaling in cardiomyocytes mlao04270   Vascular smooth muscle contraction mlao04371   Apelin signaling pathway mlao04540   Gap junction mlao04611   Platelet activation mlao04713   Circadian entrainment mlao04714   Thermogenesis mlao04723   Retrograde endocannabinoid signaling mlao04724   Glutamatergic synapse mlao04725   Cholinergic synapse mlao04727   GABAergic synapse mlao04750   Inflammatory mediator regulation of TRP channels mlao04911   Insulin secretion mlao04912   GnRH signaling pathway mlao04913   Ovarian steroidogenesis mlao04914   Progesterone-mediated oocyte maturation mlao04915   Estrogen signaling pathway mlao04916   Melanogenesis mlao04918   Thyroid hormone synthesis mlao04921   Oxytocin signaling pathway mlao04922   Glucagon signaling pathway mlao04923   Regulation of lipolysis in adipocytes mlao04925   Aldosterone synthesis and secretion mlao04926   Relaxin signaling pathway mlao04927   Cortisol synthesis and secretion mlao04928   Parathyroid hormone synthesis, secretion and action mlao04934   Cushing syndrome mlao04935   Growth hormone synthesis, secretion and action mlao04970   Salivary secretion mlao04971   Gastric acid secretion mlao04972   Pancreatic secretion mlao04976   Bile secretion mlao05032   Morphine addiction mlao05163   Human cytomegalovirus infection mlao05166   Human T-cell leukemia virus 1 infection mlao05200   Pathways in cancer mlao05207   Chemical carcinogenesis - receptor activation mlao05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mlao00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     141496820 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     141496820 (ADCY2)    04371 Apelin signaling pathway     141496820 (ADCY2)    04020 Calcium signaling pathway     141496820 (ADCY2)    04072 Phospholipase D signaling pathway     141496820 (ADCY2)    04024 cAMP signaling pathway     141496820 (ADCY2)    04022 cGMP-PKG signaling pathway     141496820 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     141496820 (ADCY2)    04081 Hormone signaling     141496820 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     141496820 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     141496820 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     141496820 (ADCY2)    04062 Chemokine signaling pathway     141496820 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     141496820 (ADCY2)    04922 Glucagon signaling pathway     141496820 (ADCY2)    04923 Regulation of lipolysis in adipocytes     141496820 (ADCY2)    04912 GnRH signaling pathway     141496820 (ADCY2)    04913 Ovarian steroidogenesis     141496820 (ADCY2)    04915 Estrogen signaling pathway     141496820 (ADCY2)    04914 Progesterone-mediated oocyte maturation     141496820 (ADCY2)    04921 Oxytocin signaling pathway     141496820 (ADCY2)    04926 Relaxin signaling pathway     141496820 (ADCY2)    04935 Growth hormone synthesis, secretion and action     141496820 (ADCY2)    04918 Thyroid hormone synthesis     141496820 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     141496820 (ADCY2)    04916 Melanogenesis     141496820 (ADCY2)    04925 Aldosterone synthesis and secretion     141496820 (ADCY2)    04927 Cortisol synthesis and secretion     141496820 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     141496820 (ADCY2)    04270 Vascular smooth muscle contraction     141496820 (ADCY2)   09154 Digestive system    04970 Salivary secretion     141496820 (ADCY2)    04971 Gastric acid secretion     141496820 (ADCY2)    04972 Pancreatic secretion     141496820 (ADCY2)    04976 Bile secretion     141496820 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     141496820 (ADCY2)    04727 GABAergic synapse     141496820 (ADCY2)    04725 Cholinergic synapse     141496820 (ADCY2)    04723 Retrograde endocannabinoid signaling     141496820 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     141496820 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     141496820 (ADCY2)    04213 Longevity regulating pathway - multiple species     141496820 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     141496820 (ADCY2)    04714 Thermogenesis     141496820 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     141496820 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     141496820 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     141496820 (ADCY2)    05163 Human cytomegalovirus infection     141496820 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     141496820 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     141496820 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     141496820 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     141496820 (ADCY2) Enzymes [BR:mlao01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      141496820 (ADCY2) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  141496820 NCBI-ProteinID:  XP_074055509 LinkDB All DBs Position X:342036845..342590163 Genome browser AA seq 1097 aa AA seqDB search MWQEAMRRRRYLLDRAEAAAGGGGGAGGCGGRLHKSRDWLYESYYCMSQQHPLIVFLLLI IMGACLALLSVFFALGLEVKEHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVI WVCLVAMGYLFMCFEGSIFPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSASHTIVL SVCLSTTTGVKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKL EFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQLENTNNFHNLYVKRHTNVSILY ADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPN HAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLA NHMEAGGVPGRVHITSVTLEHLNGAYKVEEGDGEIRDPYLKEHYVKTYFVINPKGERRSP QHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQH HFQHRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKTLEKEYR ATTLPAFKYYVTCACLIFFGIFIVQILVLPKTSILGISFGAAFLFLSFILFICFAGQLLQ CSKKASASLLWILKSSGIIANRPWPRITLTVTTTTIILTMAIFNMFFLNEAQIMFPSDFN TSNSSFPDSADHNSQNKQKYFFLPYFIYSCILGLISCSVFLRINYELKMMIMLIALVGYN IILLHTHAPILDGYSNFLIERPGIWKDLKIMGSVSLFIFFITLLVLGRQNEYYCRLDFLW KNKFNKEREEIETMENLNRVLLENVLPAHVAEHFLARNLKNEDLYHQSYDCVCVMFASIP DFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAT PSQEHTQEPERQYMHIGTMVEFAFALAAKLDVINKHSFNDFKLRVGINHGPVIAGVIGAQ KPQYDIWGNTVNVASRMDSTGVLDKIQVTEETNIVLQTLGYMCTCRGIINVKGKGELKTY FVHTEMARSLSQANVAS NT seq 3294 nt NT seq  +upstreamnt  +downstreamnt atgtggcaagaggcgatgaggaggcgccgctatctgctggaccgggcagaggctgccgcg ggcggcggcggcggggccgggggctgcggcggccggctgcacaagtcccgggactggctc tacgagtcctactactgtatgagccagcagcacccgctcatcgtcttcctgttgctaatt atcatgggcgcctgcctagccctcctctccgtcttctttgctttggggctggaagttaaa gaacatgtggcatttttaataacagttccaacagcccttgctattttcttcgcaatattt attcttgtctgcattgaatctgtatttaagaagctgcttcgtgttttctccttggtaata tgggtttgcctcgttgccatgggatatttattcatgtgttttgaaggctccatctttcct tgggaccaggtatcattttttttattcattatctttgtggtatacactatgctgcctttc aacatgagagatgccataattgccagtgtgctgacctctgcatcccacaccattgtgctg agtgtctgtctctccaccacaacaggagtaaaggagcacttggtctggcagatactagca aatgttatcattttcatatgtggaaacctggcaggagcctaccacaagcatctcatggaa ctggctctacagcagacctatcaggacacctgtaattgcattaagtccagaatcaagttg gaatttgaaaagcggcagcaggagcgtcttctgctctctttactgcctgctcacatcgcc atggaaatgaaagcagagatcattcagagattgcagggacccaaagcaggccagctggaa aatacaaacaattttcacaatctctatgtcaaacgacacaccaatgtgagcatattatat gctgacattgttggattcacccgtctggctagtgactgctctccaggagaactggtgcac atgctgaatgaactctttggaaagtttgatcaaattgccaaggaaaatgaatgcatgaga atcaaaattttaggagactgctactactgtgtgtctggcctccctatatctcttccaaat catgccaagaattgtgtgaaaatgggacttgatatgtgtgaagccataaagaaagtaaga gatgcaaccggagttgacatcaacatgcgtgtgggagtccactctgggaacgtcctctgt ggtgtaattggtttgcagaagtggcagtatgatgtctggtctcatgatgttacacttgca aatcacatggaagctggaggtgtgccaggacgtgttcacattacttcagtcaccttagag catttgaatggagcttacaaagtagaagaaggagatggagaaatcagggacccatatctg aaggaacattatgtcaaaacctattttgtgatcaaccccaagggagaaagacgaagtcct cagcacctttttaggccaaggcatacattagatggagccaagatgagagcatctgtccgc atgacccggtatttggagtcctggggagcagccaagccctttgcacatttgcatcatagg gacagcatgacaacagaaaacggcaaaatcagtaccacagatgtgccaatgggtcagcat cactttcagcaccgcacattaagaaccaaatcacagaagaaaagatttgaagaagaattg aatgaaagaatgattcaagcaattgatggaatcaatgctcaaaagcagtggctcaaatct gaagatattcaaagaatttctctacttttctataacaaaacacttgagaaagaatacaga gcaactacattacctgcattcaagtattatgtgacttgtgcttgtctcatcttctttggc atctttattgtgcagatattagtattaccaaaaacatctattcttgggatttcctttgga gctgcatttctcttcctttccttcatccttttcatctgttttgctggacagctgctgcaa tgcagcaaaaaagcatctgcctcattattatggattttgaagtcatctggaataattgca aatcgtccctggccacggatcactctcacagttaccaccactaccattatattaaccatg gccatcttcaacatgtttttcctgaatgaggcacagataatgttcccctcagatttcaac acatcaaattcaagtttcccagactctgctgaccacaattctcagaataaacaaaagtat tttttcctgccgtacttcatttacagctgcattctgggcttgatatcctgttctgttttt ctgcggataaactatgaattgaaaatgatgatcatgctgattgcacttgtgggttacaat atcatccttttacatacacatgcccctattcttgatggctacagtaactttctcattgaa agaccaggcatatggaaagacctaaagattatgggttctgtgtctctctttatatttttc atcacattactggttctggggagacagaatgaatattactgtaggttagacttcctatgg aagaacaagttcaataaagagcgtgaggaaattgaaaccatggagaacctgaatcgtgtc ctgctggaaaatgtgctccctgcccatgtggccgaacacttcttggccagaaacttgaag aatgaggacttgtatcatcagtcctatgactgtgtctgtgtcatgtttgcctctattccg gatttcaaagaattttatacagaatcagatgtcaacaaagaaggcttagagtgtctcaga ctcctgaatgagatcattgcagattttgatgatttgctgtccaaaccaaaatttagtgga gttgaaaagatcaagaccattggaagcacttatatggcagccacaggactgagtgccacc cctagccaagaacacacacaggagcctgagcgccagtacatgcacattggcaccatggtt gagtttgcttttgccctggcagctaaattggatgtaatcaacaaacattccttcaatgac ttcaagttgcgagtgggtataaaccatggtccggtaatagctggtgtaattggagctcag aaacctcagtatgatatctggggcaacacagtaaatgtggccagcaggatggatagtact ggagtcttagataaaatacaggtcactgaggagacaaacattgtcttgcagacattaggc tacatgtgcacttgcagaggaataatcaacgtgaaaggaaagggtgaactgaagacatat tttgtacatacagaaatggcaaggtccctttcccaggcaaatgtggcatcctga

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