Macrotis lagotis (bilby): 141499941
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Entry
141499941 CDS
T11097
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao01522
Endocrine resistance
mlao04012
ErbB signaling pathway
mlao04062
Chemokine signaling pathway
mlao04148
Efferocytosis
mlao04151
PI3K-Akt signaling pathway
mlao04360
Axon guidance
mlao04370
VEGF signaling pathway
mlao04510
Focal adhesion
mlao04517
IgSF CAM signaling
mlao04518
Integrin signaling
mlao04670
Leukocyte transendothelial migration
mlao04810
Regulation of actin cytoskeleton
mlao04935
Growth hormone synthesis, secretion and action
mlao05100
Bacterial invasion of epithelial cells
mlao05135
Yersinia infection
mlao05146
Amoebiasis
mlao05163
Human cytomegalovirus infection
mlao05165
Human papillomavirus infection
mlao05170
Human immunodeficiency virus 1 infection
mlao05200
Pathways in cancer
mlao05202
Transcriptional misregulation in cancer
mlao05205
Proteoglycans in cancer
mlao05208
Chemical carcinogenesis - reactive oxygen species
mlao05222
Small cell lung cancer
mlao05417
Lipid and atherosclerosis
mlao05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
141499941 (PTK2)
04370 VEGF signaling pathway
141499941 (PTK2)
04151 PI3K-Akt signaling pathway
141499941 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
141499941 (PTK2)
04518 Integrin signaling
141499941 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
141499941 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
141499941 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
141499941 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
141499941 (PTK2)
04062 Chemokine signaling pathway
141499941 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
141499941 (PTK2)
09158 Development and regeneration
04360 Axon guidance
141499941 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
141499941 (PTK2)
05202 Transcriptional misregulation in cancer
141499941 (PTK2)
05205 Proteoglycans in cancer
141499941 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
141499941 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
141499941 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
141499941 (PTK2)
05163 Human cytomegalovirus infection
141499941 (PTK2)
05165 Human papillomavirus infection
141499941 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
141499941 (PTK2)
05100 Bacterial invasion of epithelial cells
141499941 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
141499941 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
141499941 (PTK2)
05418 Fluid shear stress and atherosclerosis
141499941 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
141499941 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlao01001
]
141499941 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
mlao01009
]
141499941 (PTK2)
Enzymes [BR:
mlao01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
141499941 (PTK2)
Protein kinases [BR:
mlao01001
]
Non-receptor tyrosine kinases
FAK family
141499941 (PTK2)
Protein phosphatases and associated proteins [BR:
mlao01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
141499941 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
141499941
NCBI-ProteinID:
XP_074058836
LinkDB
All DBs
Position
X:complement(611955417..612376037)
Genome browser
AA seq
1103 aa
AA seq
DB search
MLLELAGQQALKPAGAIYMEKSGCSPFPICWAKEYDRYLASSKTMAAAYLDPNLNHAPSS
STKTHLSTGMERSPGAMERVLKVFHYFENSSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKNDYMLEIADQVDQEIALKLGCLEIRRSYGEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLESVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFNQVQTIQYSNNDDKDRKGML
QLKISGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANNEKQGVRTHTVSVSETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIG
EGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGV
ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAA
RNVLVSSTDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG
VCMWEILMHGIKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF
TELKAQLSTILEEEKLQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGF
YPSPQHMVQANHYQVSGYPGSHGITAMAGSIYPGQASLLDQTESWNHRPQEVSMWQPNME
DSATLDMRGLGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDG
SLQGPTGNQHIYQPVGKPDHAAPPKKPPRPGAPSHLGSLASLNSPVDSYNEGVKLQPQEI
SPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVD
ETIPMLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAV
DAKNLLDVIDQARLKMLGQARPH
NT seq
3312 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggctggccaacaggccctgaaaccagcaggtgctatctatatggag
aaaagcggctgtagcccatttccaatatgttgggctaaagaatatgacagatacctagca
tctagcaaaaccatggcagctgcttatcttgacccaaacttgaatcatgccccaagttca
agtacaaagacacacctcagtactggaatggagcgttcacctggggcaatggagcgagta
ttaaaagtctttcattattttgaaaatagtagtgagccaaccacatgggccagtattatc
aggcatggagatgccactgatgtaaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgttacggatttcgactcagtcatcttcgttcagaggaagttcac
tggctacatttggatatgggtgtttccaatgtgagagaaaaatatgagctagcccaccca
ccggaggagtggaaatatgagttgagaatacgttacttgccaaaaggatttttgaaccag
tttacagaagacaagccaactttgaatttcttttatcagcaggtgaaaaacgactatatg
ttagaaatagcagatcaagtggaccaggaaattgctttgaagttgggttgccttgaaata
cggagatcgtatggggagatgaggggaaatgccctagagaagaaatctaactatgaagta
ttagaaaaggatgttggtttaaagagattttttcctaagagtttgctggaatctgtcaag
gccaaaactctcagaaaactgatacagcaaacatttcgacaatttgccaatcttaataga
gaagaaagtatcctgaaattctttgagattctctctcctgtatacagattcgataaagaa
tgcttcaaatgtgctcttgggtcaagttggatcatttccgtggagctggcaatcggccca
gaagaaggcatcagctaccttacagacaagggctccaatcctacacatcttgcagacttc
aatcaagttcagactattcagtattcaaacaatgatgacaaagacagaaaaggaatgcta
caactcaaaatatcaggagcacctgagcctctcacagtgacagccccatctttaaccatt
gctgagaatatggctgacttaatagatggatattgccgactagttaatggagccacacaa
tcttttatcattagaccccaaaaagaaggtgaacgagccttaccatccataccaaagcta
gccaacaatgagaagcaaggagtaagaacacatacagtctctgtatcagaaacagatgac
tatgctgagattatagatgaagaagatacttatacaatgccttcaaaaagctatggaata
gatgaagccagggattatgaaatacaaagagaaaggatagaacttggacgctgcattgga
gaaggccagtttggagatgtacatcaaggagtttacatgagtccagagaatccagcaatg
gcagttgcaattaaaacctgtaaaaactgtacctcagacagtgtgagagaaaaattcctt
caagaagccttaacaatgcgtcagtttgatcacccacatattgtgaagctgattggtgtt
ataacagaaaaccctgtctggataatcatggaactctgcacattaggggagctgagatca
tttttgcaagtgagaaaatacagcttggatttggcatctttgattctatatgcttaccag
cttagtacagcccttgcctacctagaaagtaaaagatttgtgcatagggacattgctgct
agaaatgtgctggtatcttcaactgactgtgtaaaattaggagattttggtttgtctcga
tatatggaagatagtacttactacaaagcttccaaaggaaaattacctattaaatggatg
gctccagagtcaatcaactttagacgttttacctcagctagtgatgtgtggatgtttggt
gtatgcatgtgggaaattttgatgcatggtataaaacctttccaaggagtgaagaacaat
gatgtaattggtcgaattgaaaatggtgaacggttgccaatgcctccaaattgtcctcct
actctctacagccttatgacaaaatgctgggcatatgatcccagcagacgacccaggttt
actgaactcaaagcacagctcagtacaatactggaggaggagaagcttcagcaagaagaa
cgaatgagaatggaatccagaaggcaggtcacagtgtcctgggattcaggaggctcagac
gaagctcctcccaagcccagccgacctggctatcctagcccaaggtccagtgaaggtttc
tatcctagtccacaacacatggtacaagccaatcattatcaggtctctggctatcctggt
tctcatggaataacagccatggctggcagcatttatcctggtcaggcatctcttttggac
caaacagagtcttggaatcatcgacctcaggaagtatcaatgtggcagcccaacatggag
gactctgccacattggacatgaggggattaggccaagtccttccagcacatcttatggaa
gagaggttgatacgacagcaacaggaaatggaggaagatcaacgatggcttgagaaggag
gagagatttttgaaaccagatgtgaggctctctcgaggcagcattgaccgagaggatgga
agtcttcagggtccgactggtaaccagcatatatatcagcccgtgggtaagccagatcat
gcagcaccaccaaagaaaccacctcgcccaggagcccccagccatttgggaagccttgcc
agcctcaatagtcctgtggatagctataatgagggagtgaagctgcagccccaagaaatc
agcccccctcctactgccaatctagatcgctccaatgacaaggtctatgagaatgtaact
ggtctggtgaaagctgtcatagaaatgtccagcaagatacagcctgcacccccagaggaa
tatgttcctatggtaaaggaagttggcttggccctacgaacattgctagcaacagtggat
gagaccattcctatgctccccgccagcactcacagagagattgagatggcccaaaagctg
ttgaattcggacttgggtgaactgatcaacaaaatgaaactggcacaacagtacgtcatg
accagcctccagcaggaatacaaaaagcagatgctaactgctgctcatgccctggctgtg
gatgccaagaacttactggatgtcattgatcaagcacgattgaaaatgctggggcaggcc
aggccacactga
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