Macrotis lagotis (bilby): 141501625
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Entry
141501625 CDS
T11097
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao04014
Ras signaling pathway
mlao04072
Phospholipase D signaling pathway
mlao04148
Efferocytosis
mlao04360
Axon guidance
mlao04517
IgSF CAM signaling
mlao04625
C-type lectin receptor signaling pathway
mlao04630
JAK-STAT signaling pathway
mlao04650
Natural killer cell mediated cytotoxicity
mlao04660
T cell receptor signaling pathway
mlao04670
Leukocyte transendothelial migration
mlao04722
Neurotrophin signaling pathway
mlao04920
Adipocytokine signaling pathway
mlao04931
Insulin resistance
mlao05168
Herpes simplex virus 1 infection
mlao05205
Proteoglycans in cancer
mlao05208
Chemical carcinogenesis - reactive oxygen species
mlao05211
Renal cell carcinoma
mlao05220
Chronic myeloid leukemia
mlao05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
141501625 (PTPN11)
04630 JAK-STAT signaling pathway
141501625 (PTPN11)
04072 Phospholipase D signaling pathway
141501625 (PTPN11)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
141501625 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
141501625 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
141501625 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
141501625 (PTPN11)
04660 T cell receptor signaling pathway
141501625 (PTPN11)
04670 Leukocyte transendothelial migration
141501625 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
141501625 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
141501625 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
141501625 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
141501625 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
141501625 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
141501625 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
141501625 (PTPN11)
05211 Renal cell carcinoma
141501625 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
141501625 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
141501625 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mlao01009
]
141501625 (PTPN11)
Enzymes [BR:
mlao01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
141501625 (PTPN11)
Protein phosphatases and associated proteins [BR:
mlao01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
141501625 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
141501625
NCBI-ProteinID:
XP_074061885
LinkDB
All DBs
Position
X:673211830..673281457
Genome browser
AA seq
603 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESTDGKSKVTHVMIRCQDLKYD
VGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRPENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGAMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPTDPGGVLDFLEEVHHKQESIPDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTCGDQSPLPPCTPTPTCPEYDYSSPPPKGQERCKDFHVKKEFGR
FAF
NT seq
1812 nt
NT seq
+upstream
nt +downstream
nt
atgacatcccggagatggtttcacccaaatatcactggagtggaggcagaaaatttactg
ctgacacgaggcgttgatggcagctttttggccaggcccagtaagagtaatccaggagac
ttcaccctttctgtgaggcggaatggtgctgtcactcacatcaagattcagaacaccggt
gactattatgatctgtatggtggagagaagtttgccacactggctgagttagtgcagtat
tacatggagcaccatgggcagctgaaagaaaagaacggcgatgtcatcgaactcaaatac
ccgctgaactgtgcagaccctacctctgagagatggtttcatgggcacctctctgggaaa
gaagcagagaaattactaactgagaaaggcaaacatggaagtttcttggtacgagaaagc
cagagccacccgggggactttgttctctccgtccgcacaggggatgataaaggcgagagt
accgatggcaaatcaaaagtgacgcacgtcatgattcgctgccaggatctgaaatatgac
gtcggtggaggggagaagtttgattctctaacagatcttgtagaacattacaagaagaac
cctatggtggaaactctgggtacagtgctacagctcaagcagcccctgaatacaactcgc
attaatgctgcagagatcgaaagccgtgtaagagaactaagcaaattagctgagaccaca
gataaagttaaacaaggtttttgggaagaatttgagactctacaacaacaagaatgcaaa
ctcctatatagtcgtaaagagggtcagcgaccagaaaataaaaacaaaaacagatataag
aacattttaccatttgatcataccagagttgttctgcatgatggggatccaaatgaacca
gtttcagattacatcaatgcaaacattatcatgcctgaatttgagaccaagtgcaacaat
tcaaaacccaaaaaaagttatattgcaactcaaggctgtctacagaacacagtgaatgac
ttttggagaatggtgttccaggagaattctcgagttattgtcatgacaacgaaagaagta
gagagaggcaagagcaaatgtgtcaagtactggcctgatgaatatgctctaaaggagtat
ggggccatgcgcgttaggaatgttaaagaaagtgctgctcatgactatacgctccgagag
cttaaactctccaaggttggacaagctctacttcaggggaacacagagagaacagtgtgg
cagtatcattttagaacctggcctgatcacggcgtgcccaccgatcctggaggagttctg
gactttttagaagaggtccatcacaagcaggagagcatccctgacgcaggcccagtggtg
gtgcattgcagtgctgggattggcaggacaggcactttcattgtgattgacatccttatt
gacattatcagagagaaaggtgtggattgtgatattgatgttcccaaaaccattcagatg
gtgagatcccaaaggtcagggatggtccagacagaagcccagtacagatttatctacatg
gctgtgcagcattatatagaaacgctacagcgcagaattgaggaggagcagaaaagtaag
agaaaagggcatgaatatacaaacattaaatattctctagcggaccagacatgtggagat
caaagtcctcttcccccctgcaccccaactccaacctgtccagaatatgactattcctcc
ccacccccaaaaggtcaagaaagatgcaaggactttcatgtgaagaaagaatttggaagg
tttgcattctga
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