Macrotis lagotis (bilby): 141505869
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Entry
141505869 CDS
T11097
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao04120
Ubiquitin mediated proteolysis
mlao04144
Endocytosis
mlao04330
Notch signaling pathway
mlao04668
TNF signaling pathway
mlao04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
141505869 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
141505869 (ITCH)
04668 TNF signaling pathway
141505869 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
141505869 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
141505869 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlao04131
]
141505869 (ITCH)
04121 Ubiquitin system [BR:
mlao04121
]
141505869 (ITCH)
Enzymes [BR:
mlao01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
141505869 (ITCH)
Membrane trafficking [BR:
mlao04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
141505869 (ITCH)
Ubiquitin system [BR:
mlao04121
]
Ubiquitin ligases (E3)
HECT type E3
141505869 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
141505869
NCBI-ProteinID:
XP_074068223
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Position
1:complement(357529560..357702316)
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AA seq
872 aa
AA seq
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MSGSSSRSGSVGGLTMKSQLQIIVISAKLKENKKNWFGPSPYVEVSVDGQSKKTEKCSNT
NSPKWKQSLTVIVTPISKLNFRVWSHQTLKSDVLLGSAALDIHETLKSNNMKLDEVIVTL
QLLGDKEPTEVIGDLSVCLDGLQVDPEILTNGYATCSEGSSQSDDSRTRKDARSNASGPE
NAEEPGPSENRKVNGNNSPSLTNGSFKPSRPPRPSRPPPPTPRKPASVNGSPSAPSETPV
SSTESSPSTNMSAIPEGATAGAVVPTTGTLTTPPTSRQVQPVNSASQQLNTVNQGPLPPG
WEQRVDQHGRVYYVDHVEKRTSWDRPEPLPPGWERRVDNMGRVYYVDHFTRTTTWQRPTL
ESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTSTQNKEFDPLGPLPPGWEKRTDNN
GRVYFVNHNTRITQWEDPRNQGQLNEKPLPEGWEMRFTVDGVPYFVDHNRRTTTYIDPRT
GKSALDNGPQIAYVRDFKAKVHYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQ
DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYIN
PDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWV
KENNIEECGLEMYFSVDKEILGEIKSHELKPNGSNILVTEENKEEYIRMVAEWRLSRGVE
EQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMW
FWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTC
FNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2619 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtagttcacggtcagggtctgtggggggattgaccatgaaatcacaactt
cagatcattgtcatctcagcgaaacttaaagaaaataaaaagaactggtttggaccaagt
ccttatgtggaagtctcagtagatggacagtcaaagaagacagaaaaatgcagcaatacc
aacagtcccaagtggaagcaatctcttactgtaattgtcacaccaatcagcaaattaaat
tttcgtgtatggagtcaccagacattaaaatccgatgttttactgggaagtgctgctcta
gatattcatgaaacgttaaagtcaaataatatgaaacttgatgaagtgattgtgacatta
caacttctgggtgacaaggagccaacagaagtcataggagacttgtcagtttgtcttgat
ggactccaagtagatcctgagattctaacaaatggctatgctacatgttcagaaggtagt
tcacagagtgatgattccagaaccagaaaagatgcaagatcaaatgcaagtggacctgaa
aatgctgaggaaccaggacccagtgaaaataggaaggtcaatggcaataattctccatca
ctcacaaatggaagttttaaaccttctagacctccaagaccttcacggccacctcctccc
actcctcggaaaccagcatctgtcaatggttctccatctgcaccttctgaaactcctgtg
tctagtacagagtcatcaccgtcaacaaatatgagtgctattcctgaaggagcaacagct
ggagcagtggttcccaccaccgggactttaacaactcctccaacttctagacaagttcag
ccagttaattcagcttctcagcaactcaatacagttaatcaaggtccccttccacctggt
tgggaacagagagtggaccagcacggacgagtctactatgttgatcatgttgaaaaacga
acatcatgggatagaccagaacctcttcctcctggttgggaacgtcgagttgacaacatg
ggacgtgtttattatgttgaccacttcacaagaactaccacctggcagcggccaactttg
gagtcagttcgaaactatgagcagtggcaattacaacgaagtcaactccaaggagcaatg
cagcagtttaaccagagattcatttatgggaatcaagatttgtttacttcaactcaaaat
aaagaatttgatcctcttggacctctgccaccaggttgggagaagagaacagacaacaat
ggcagagtatattttgtcaatcacaacacacgtattacacaatgggaagatcccagaaat
cagggtcagttaaatgagaagcctttacccgaaggctgggaaatgagatttacagtggat
ggggttccatattttgtggatcataataggaggacaacaacatatatagatccccgaaca
ggaaaatctgctctagacaatggaccccaaatagcctatgtcagggatttcaaggcaaaa
gttcactattttcgtttctggtgtcagcaattggctatgccacaacacatcaagattaca
gtgacaagaaaaactttgtttgaagattcatttcagcagataatgagtttcaatccccag
gatcttcgaagacgtttgtgggttatttttccaggagaagaaggtttagattatggagga
gtggcgagagaatggttctttctgttgtcacatgaagtgctgaatccaatgtattgcctg
tttgaatatgcagggaaggataactactgtttgcagataaacccagcttcttatatcaat
ccagatcatctaaaatacttccggtttattggcaggtttattgccatggcattattccat
ggaaaattcatagatacaggcttttctttaccattctataaacgtatcttgaacaaacca
gttggactcaaagatttagaatctatcgatccagaattttacaattctctcatctgggtt
aaagaaaacaatatcgaagaatgtggtttagagatgtacttctcagttgataaggaaatt
cttggtgaaattaagagtcatgaactaaaacccaatggcagtaatattctagtaacagaa
gaaaataaagaagaatacattagaatggtagctgaatggagattatctcgtggtgttgaa
gaacagacacaagctttctttgaaggtttcaatgaaattcttccccagcagtacctgcaa
tactttgatgctaaggagctagaggtacttttgtgtggaatgcaagagattgatttaaat
gattggcaaagacatgctatctaccgacattatactaggacaagcaaacaaatcatgtgg
ttttggcagtttgtgaaagaaattgacaatgagaagagaatgaggctgttgcagtttgtt
actggaacatgcaggttgccagttgggggatttgctgacctcatggggagcaatggacca
caaaagttttgcattgaaaaagttgggaaagaaaattggttacctagaagtcatacctgt
tttaaccgcttggatctaccaccctacaagagctatgaacaactgaaagaaaaattgtta
tttgctattgaggaaacagaaggatttggacaagagtaa
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