Macrotis lagotis (bilby): 141513213
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Entry
141513213 CDS
T11097
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X1
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
mlao Macrotis lagotis (bilby)
Pathway
mlao04330
Notch signaling pathway
mlao04722
Neurotrophin signaling pathway
mlao05010
Alzheimer disease
mlao05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mlao00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
141513213 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
141513213 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
141513213 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
141513213 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mlao01002
]
141513213 (PSEN2)
Peptidases and inhibitors [BR:
mlao01002
]
Aspartic peptidases
Family A22: presenilin family
141513213 (PSEN2)
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GFIT
Motif
Pfam:
Presenilin
DUF6541
Motif
Other DBs
NCBI-GeneID:
141513213
NCBI-ProteinID:
XP_074078930
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Position
2:132251084..132292762
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AA seq
457 aa
AA seq
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MITFMNSDSEEEVCNERTSLMSTESPPARASYHEGICTEERDKEIQEKRRGSLCNHGDAD
QCTPDSRGSSRSSSLEEDEEEEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVRFYTEK
NGQLIYTPFTEDTPSIGQRLLNSVLNTLIMISVIIVMTIFLVVLYKYRCYKFIHGWLILS
SLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLVIWNFGAVGMICIHWKGPLVLQQAYLIMI
SALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYS
SAMVWTVGMAKVDTPTKGALPKDQEQDEDSSNTSGDHSYSETYDSPRCTPLHVPSYAVEE
LEEEEERGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKK
ALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgatcacattcatgaattccgacagcgaggaggaagtctgcaatgagaggacgtccctg
atgtcaacagagagccccccagcaagggcatcctatcatgaagggatctgcacagaagaa
agggacaaggagatccaagagaaacgccgaggcagcctgtgtaaccatggcgatgctgac
cagtgtacccctgatagcaggggctcatcgagaagcagcagcctggaggaggacgaagaa
gaagaagagctgacgctcaagtatggggcaaagcacgtgatcatgctgtttgtgccagtc
actctctgcatggtggtcgtcgtggcaaccattaagtcagtccgcttctacacagagaag
aatggacagttaatctacacgccctttacagaagacacaccctctattggtcagcgcttg
ctcaactccgtgctcaacaccctcatcatgatcagtgtcatcattgtcatgaccatattc
ctggttgtgctgtacaagtatcgctgctacaagtttatccatggctggttgatcctatct
tctctgatgctgctcttcctcttcacttacatttatcttggggaagtgctcaagacttac
aatgtggcaatggattatccaactcttttcttggtcatctggaattttggggcagtggga
atgatctgtatccactggaagggccccctggtgctgcagcaggcctatctcatcatgatc
agcgccctcatggccttggtcttcatcaagtaccttccagaatggtcagcctgggtcatc
ctgggagccatctctgtgtatgatcttgtggctgtgctctgtcctaaggggcccttgagg
atgcttgtagaaactgctcaggaaagaaatgaacctatatttcctgcactcatctattca
tctgccatggtgtggactgtaggcatggccaaggtggacactccaacaaagggagccctc
cccaaggaccaggagcaagatgaagactcaagcaacacttctggggatcactcttactct
gaaacctatgactctccaaggtgcaccccactccatgtgccttcctatgcagtggaggag
ctggaggaagaggaggaaagaggagtgaagcttggcctgggagatttcattttctacagt
gttcttgtgggcaaggcagcagccacggcaagtggggactggaacacaacactagcctgc
tttgttgccattcttattgggctgtgtttgacactcttgctgctggcagtgttcaagaag
gctttgcctgccctgcccatctccatcaccttcggtctcatcttctacttctccactgac
aaccttgtgaggcctttcatggacaccctggcatctcaccagttgtacatttag
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